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Volumn 44, Issue 4, 1998, Pages 688-691

Ganaxolone, a selective, high-affinity steroid modulator of the γ- aminobutyric acid-A receptor, exacerbates seizures in animal models of absence

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; GANAXOLONE; PENTETRAZOLE;

EID: 0031722019     PISSN: 03645134     EISSN: None     Source Type: Journal    
DOI: 10.1002/ana.410440417     Document Type: Article
Times cited : (41)

References (21)
  • 1
    • 0030472538 scopus 로고    scopus 로고
    • Neuroactive steroids protect against pilocarpine- and kainic acid-induced limbic seizures and status epilepticus in mice
    • Kokate TG, Cohen AL, Karp E, Rogawski MA. Neuroactive steroids protect against pilocarpine- and kainic acid-induced limbic seizures and status epilepticus in mice. Neuropharmacology 1996;35:1049-1056
    • (1996) Neuropharmacology , vol.35 , pp. 1049-1056
    • Kokate, T.G.1    Cohen, A.L.2    Karp, E.3    Rogawski, M.A.4
  • 2
    • 0026509649 scopus 로고
    • A receptor. Mechanism of action and physiological significance
    • A receptor. Mechanism of action and physiological significance. Prog Neurobiol 1992;38:370-395
    • (1992) Prog Neurobiol , vol.38 , pp. 370-395
    • Majewska, M.D.1
  • 5
    • 0028801074 scopus 로고
    • A receptor complex: The pharmacological properties and therapeutic potential of epalons
    • A receptor complex: the pharmacological properties and therapeutic potential of epalons. Crit Rev Neurobiol 1995;9:207-277
    • (1995) Crit Rev Neurobiol , vol.9 , pp. 207-277
    • Gee, K.W.1    McCauley, L.2    Lan, N.C.3
  • 6
    • 0028896579 scopus 로고
    • Basic mechanism of generalized absence seizures
    • Snead OC. Basic mechanism of generalized absence seizures. Ann Neurol 1995;37:146-157
    • (1995) Ann Neurol , vol.37 , pp. 146-157
    • Snead, O.C.1
  • 7
    • 0018870618 scopus 로고
    • Antagonism of γ-hydroxybutyric acid-induced frequency shifts in the cortical EEG of rats by dipropylacetate
    • Bearden LJ, Snead OC, Healey CT, Pegram GV. Antagonism of γ-hydroxybutyric acid-induced frequency shifts in the cortical EEG of rats by dipropylacetate. Electroencephalogr Clin Neurophysiol 1980;49:181-183
    • (1980) Electroencephalogr Clin Neurophysiol , vol.49 , pp. 181-183
    • Bearden, L.J.1    Snead, O.C.2    Healey, C.T.3    Pegram, G.V.4
  • 8
    • 0026099272 scopus 로고
    • The γ-hydroxyburyrate model of absence seizures: Correlation of regional brain levels of γ-hydroxybutyric acid and γ-butyrolactone with spike wave discharges
    • Snead OC. The γ-hydroxyburyrate model of absence seizures: correlation of regional brain levels of γ-hydroxybutyric acid and γ-butyrolactone with spike wave discharges. Neuropharmacology 1991;30:161-167
    • (1991) Neuropharmacology , vol.30 , pp. 161-167
    • Snead, O.C.1
  • 9
    • 0024459399 scopus 로고
    • Suppressive effects of intranigral injection of muscimol in three models of generalized non-convulsive epilepsy induced by chemical agents
    • Depaulis A, Snead OC, Marescaux C, Vergnes M. Suppressive effects of intranigral injection of muscimol in three models of generalized non-convulsive epilepsy induced by chemical agents. Brain Res 1989;498:64-72
    • (1989) Brain Res , vol.498 , pp. 64-72
    • Depaulis, A.1    Snead, O.C.2    Marescaux, C.3    Vergnes, M.4
  • 10
    • 0023272497 scopus 로고
    • Concepts of absence epilepsies: Discrete syndromes or biologic continuum?
    • Berkovic SF, Andermann F, Andermann E, Gloor P. Concepts of absence epilepsies: discrete syndromes or biologic continuum? Neurology 1987;37:993-1000
    • (1987) Neurology , vol.37 , pp. 993-1000
    • Berkovic, S.F.1    Andermann, F.2    Andermann, E.3    Gloor, P.4
  • 11
    • 0023911219 scopus 로고
    • Generalized epilepsy: Some of its cellular mechanisms differ from those of focal epilepsy
    • Gloor P, Fariello RG. Generalized epilepsy: some of its cellular mechanisms differ from those of focal epilepsy. Trends Neurosci 1988;11:63-68
    • (1988) Trends Neurosci , vol.11 , pp. 63-68
    • Gloor, P.1    Fariello, R.G.2
  • 12
    • 0023780307 scopus 로고
    • γ-Hydroxybutyrate model of generalized absence seizures: Further characterization and comparison with other absence models
    • Snead OC. γ-Hydroxybutyrate model of generalized absence seizures: further characterization and comparison with other absence models. Epilepsia 1988;29:361-368
    • (1988) Epilepsia , vol.29 , pp. 361-368
    • Snead, O.C.1
  • 13
    • 0026612477 scopus 로고
    • B-mediated mechanisms in experimental absence seizures
    • B-mediated mechanisms in experimental absence seizures. Eur J Pharmacol 1992;213:343-349
    • (1992) Eur J Pharmacol , vol.213 , pp. 343-349
    • Snead, O.C.1
  • 14
    • 0029873022 scopus 로고    scopus 로고
    • B and γ-hydroxybutyric acid receptor antagonists
    • B and γ-hydroxybutyric acid receptor antagonists. Pharmacol Biochem Behav 1996;53:73-79
    • (1996) Pharmacol Biochem Behav , vol.53 , pp. 73-79
    • Snead, O.C.1
  • 16
    • 0026611215 scopus 로고
    • B receptor activation in absence seizures of lethargic (lh/lh) mice
    • B receptor activation in absence seizures of lethargic (lh/lh) mice. Science 1992;257:398-401
    • (1992) Science , vol.257 , pp. 398-401
    • Hosford, D.A.1    Clark, S.2    Cao, Z.3
  • 17
    • 0025762396 scopus 로고
    • Evidence for a critical role of GABAergic transmission within the thalamus in the genesis and control of absence seizures in the rat
    • Liu Z, Vergnes M, Depaulis A, Marescaux C. Evidence for a critical role of GABAergic transmission within the thalamus in the genesis and control of absence seizures in the rat. Brain Res 1991;545:1-7
    • (1991) Brain Res , vol.545 , pp. 1-7
    • Liu, Z.1    Vergnes, M.2    Depaulis, A.3    Marescaux, C.4
  • 18
    • 0028174189 scopus 로고
    • B-mediated inhibition in thalamic relay neurons through effects in nucleus reticularis
    • B-mediated inhibition in thalamic relay neurons through effects in nucleus reticularis. J Physiol 1994;71:2576-2581
    • (1994) J Physiol , vol.71 , pp. 2576-2581
    • Huguenard, J.R.1    Prince, D.A.2
  • 19
    • 15644382010 scopus 로고    scopus 로고
    • The neuroactive steroid, alphaxalone, facilitates absence-like seizures induced by γ-hydroxybutyric acid [GHB] in rats
    • Abstract
    • Banerjee PK, Snead OC. The neuroactive steroid, alphaxalone, facilitates absence-like seizures induced by γ-hydroxybutyric acid [GHB] in rats. Epilepsia 1997;28(Suppl 8):113 (Abstract)
    • (1997) Epilepsia , vol.28 , Issue.8 SUPPL. , pp. 113
    • Banerjee, P.K.1    Snead, O.C.2
  • 20
    • 0031000788 scopus 로고    scopus 로고
    • Utility of the lethargic (lh/lh) mouse model of absence seizures in predicting the effects of lamotrigine, vigabatrin, tiagabine, gabapentin, and topiramate against human absence seizures
    • Hosford DA, Wang Y. Utility of the lethargic (lh/lh) mouse model of absence seizures in predicting the effects of lamotrigine, vigabatrin, tiagabine, gabapentin, and topiramate against human absence seizures. Epilepsia 1997;38:408-414
    • (1997) Epilepsia , vol.38 , pp. 408-414
    • Hosford, D.A.1    Wang, Y.2
  • 21
    • 0022378555 scopus 로고
    • Exacerbation of seizures in children by carbamazepine
    • Snead OC, Hosey LC. Exacerbation of seizures in children by carbamazepine. N Engl J Med 1985;313:916-921
    • (1985) N Engl J Med , vol.313 , pp. 916-921
    • Snead, O.C.1    Hosey, L.C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.