Enantioselectivity of pregnanolone-induced γ-aminobutyric acid(A) receptor modulation and anesthesia

Journal of Pharmacology and Experimental Therapeutics

Volumn 293, Issue 3, 2000, Pages 1009-1116

  Covey, Douglas F ^a   Nathan, Devi ^a   Kalkbrenner, Melissa ^a   Nilsson, Kent R ^a   Hu, Yuefei ^a   Zorumski, Charles F ^a   Evers, Alex S ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3ALPHA HYDROXY 5ALPHA PREGNAN 20 ONE; 4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; ANESTHETIC AGENT; ELTANOLONE; PICROTOXIN; TERT BUTYLBICYCLOPHOSPHOROTHIOATE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN MEMBRANE; CONTROLLED STUDY; DRUG BINDING SITE; DRUG MECHANISM; ENANTIOMER; GABAERGIC SYSTEM; HIPPOCAMPUS; MOUSE; NEUROMODULATION; NONHUMAN; PRIORITY JOURNAL; RAT; RIGHTING REFLEX; STRUCTURE ACTIVITY RELATION;

ANESTHETICS; ANIMALS; BICYCLO COMPOUNDS, HETEROCYCLIC; BINDING SITES; DOSE-RESPONSE RELATIONSHIP, DRUG; GABA MODULATORS; LARVA; MICE; MICE, INBRED BALB C; PREGNANOLONE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GABA-A; SPECIES SPECIFICITY; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0034048526     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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