HORMONES AND GENDER | Steroid Hormones and Sex Differences in Seizure Susceptibility

Encyclopedia of Basic Epilepsy Research

Volumn , Issue , 2009, Pages 526-533

  Reddy, D S ^a  

^a TEXAS A AND M HEALTH SCIENCE CENTER   (United States)

Author keywords

Allopregnanolone; Catamenial epilepsy; Deoxycorticosterone; GABA A receptor; Gender; Neurosteroid; Progesterone; Seizures; Testosterone

Indexed keywords

EID: 85006565850     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-012373961-2.00157-0     Document Type: Chapter

References (15)

1. G.G. Buterbaugh (1989) Estradiol replacement facilitates the acquisition of seizures kindled from the anterior neocortex in female rats. Epilepsy Research 4 207-215.
2. J. Christensen, M.J. Kjeldsen, H. Anderson, M.L. Friis and P. Sidenius (2005) Gender differences in epilepsy 46 956-960.
3. B.M. Cooke, G. Tabibnia and S.M. Breedlove (1999) A brain sexual dimorphism controlled by adult circulating androgens. Proceedings of the National Academy of Sciences of the United States of America 96 7538-7540.
4. W.A. Hauser (1997) Incidence and prevalence. J. Engel, Jr.,T.A. Pedley (Eds) Epilepsy: A Comprehensive Textbook Philadelphia: Lippincott-Raven Publishers 47-57.
5. A.G. Herzog (1991) Reproductive endocrine considerations and hormonal therapy for men with epilepsy. Epilepsia 32(Suppl. 6), S34-S37.
6. A.G. Herzog, C.L. Harden, J. Liporace, et al. (2004) Frequency of catamenial seizure exacerbation in women with localization-related epilepsy. Annals of Neurology 56 431-434.
7. J.L. Maguire, B.M. Stell, M. Rafizadeh and I. Mody (2005) Ovarian cycle-linked changes in GABA A receptors mediating tonic inhibition alter seizure susceptibility and anxiety. Nature Neuroscience 8 797-804.
8. T. Ravizza, L.K. Friedman, S.L. Moshe and J. Veliskova (2003) Sex differences in gabaergic system in rat substantia nigra pars reticulate. International Journal of Developmental Neuroscience 21 245-254.
9. D.S. Reddy (2003) Pharmacology of endogenous neuroactive steroids. Critical Reviews in Neurobiology 15 197-234.
10. D.S. Reddy (2004) Role of neurosteroids in catamenial epilepsy. Epilepsy Research 62 99-118.
11. D.S. Reddy (2006) Physiological role of adrenal deoxycorticosterone-derived neuroactive steroids in stress-sensitive conditions. Neuroscience 138 911-920.
12. D.S. Reddy (2007) Mass spectrometric assay and physiological–pharmacological activity of androgenic neurosteroids. Neurochemistry International 52(4–5), 541-553.
13. D.S. Reddy, D.A. Castenada, B.W. O’Malley and M.A. Rogawski (2004) Antiseizure activity of progesterone and neurosteroids in progesterone receptor knockout mice. Journal of Pharmacology and Experimental Therapeutics 310 230-239.
14. S.S. Smith, H. Shen, Q.H. Gong and X. Zhou (2007) Neurosteroid regulation of GABA A receptors: Focus on the α4 and δ subunits. Pharmacology and Therapeutics 116(1), 58-76.
15. J. Veliskova and S.L. Moshe (2001) Sexual dimorphism and developmental regulation of substantia nigra function. Annals of Neurology 50 596-601.