Multiple structural features of steroids mediate subtype-selective effects on human α4β3δ GABAA receptors

Biochemical Pharmacology

Volumn 68, Issue 5, 2004, Pages 819-831

  Pillai, Gopalan V ^a   Smith, Alison J ^a   Hunt, Peter A ^a   Simpson, Peter B ^a  

^a NEUROSCIENCE RESEARCH CENTRE   (United Kingdom)

Author keywords

bis (1,3 diethylthiobarbituric acid) trimethine oxonol; CC2 dimyristoyl phosphatidylethanolamine; CC2 DMPE; DiSBAC2 (3); Neurosteriods; PC; PCA; Potentiometric assay; principal component; principal components analysis; VIPR; voltage ion probe reader

Indexed keywords

17,20BETA DIHYDROXYPREGN 4 EN 3 ONE; 17ALPHA,20ALPHA DIHYDROXYPROGESTERONE; 3ALPHA HYDROXY 5ALPHA PREGNAN 20 ONE; 3ALPHA,17ALPHA DIHYDROXYPREGNAN 20 ONE; 3ALPHA,21 DIHYDROXY 5ALPHA PREGNAN 20 ONE; 3ALPHA,5BETA TETRAHYDROCORTODOXONE; 4 AMINOBUTYRIC ACID RECEPTOR STIMULATING AGENT; 4 PREGNEN 20 ALPHA OL 3 ONE; 4 PREGNENE 17ALPHA,20ALPHA DIOL 3 ON 20 ACETATE; 5 PREGNENE 3BETA,17ALPHA,20BETA TRIOL; 5ALPHA DIHYDROCORTICOSTERONE; 5ALPHA PREGNANE 3,11,20 TRIONE; 5ALPHA PREGNANE 3,20 DIONE; 5ALPHA PREGNANE 3ALPHA,20ALPHA DIOL; 5ALPHA PREGNANE 3BETA OL 20 ONE; 5ALPHA PREGNANE 3BETA,11BETA,17ALPHA,21 TETROL 20 ONE; 5ALPHA PREGNANE 3BETA,21 DIOL 20 ONE; 5BETA PREGNANE 11BETA,17ALPHA,21 TRIOL 3,20 DIONE; 5BETA PREGNANE 3ALPHA,11BETA,17ALPHA,20BETA TETROL; 5BETA PREGNANE 3ALPHA,12ALPHA DIOL 20 ONE DIACETATE; 5BETA PREGNANE 3ALPHA,17ALPHA DIOL 11,20 DIONE; 5BETA PREGNANE 3ALPHA,17ALPHA,20BETA TRIOL; 5BETA PREGNANE 3ALPHA,20ALPHA DIOL DIACETATE; 5BETA PREGNANE 3ALPHA,20BETA DIOL; ELTANOLONE; PREDNISOLONE; PREDNISOLONE ACETATE; PREDNISONE; PREGNANETRIOL; STEROID; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL LINE; CONTROLLED STUDY; DRUG EFFICACY; DRUG POTENCY; FLUORESCENCE RESONANCE ENERGY TRANSFER; GENETIC TRANSFECTION; MOLECULAR MODEL; MOUSE; NONHUMAN; POTENTIOMETRY; PRINCIPAL COMPONENT ANALYSIS; PRIORITY JOURNAL;

ANIMALS; CELLS, CULTURED; HUMANS; KINETICS; MICE; MOLECULAR CONFORMATION; PROTEIN SUBUNITS; RECEPTORS, GABA-A; STEROIDS; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSFECTION;

EID: 3843146088     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2004.05.013     Document Type: Article

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