α1 and α6 subunits specify distinct desensitization, deactivation and neurosteroid modulation of GABAA receptors containing the δ subunit

Neuropharmacology

Volumn 43, Issue 4, 2002, Pages 492-502

  Bianchi, M T ^a   Haas, K F ^a   Macdonald, Robert L ^b,c  

^a UNIVERSITY OF MICHIGAN   (United States)

^b VANDERBILT UNIVERSITY   (United States)

^c VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Concentration jump; Deactivation; Desensitization; Neurosteroid; subunit

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; ISOPROTEIN; MEMBRANE PROTEIN; NEUROSTEROID; RECEPTOR SUBUNIT; 4 AMINOBUTYRIC ACID RECEPTOR BLOCKING AGENT; AGENTS INTERACTING WITH TRANSMITTER, HORMONE OR DRUG RECEPTORS; ALPHA1 SUBUNIT, GABA A RECEPTOR; ALPHA1 SUBUNIT, GABA-A RECEPTOR; ALPHA6 SUBUNIT, GABA A RECEPTOR; ALPHA6 SUBUNIT, GABA-A RECEPTOR; DEOXYCORTICOSTERONE; DRUG DERIVATIVE; GABRD PROTEIN, HUMAN; HYBRID PROTEIN; RECOMBINANT PROTEIN; TETRAHYDRODEOXYCORTICOSTERONE;

AMINO TERMINAL SEQUENCE; AMPLITUDE MODULATION; ARTICLE; CARBOXY TERMINAL SEQUENCE; CHIMERA; CONTROLLED STUDY; CORRELATION ANALYSIS; DESENSITIZATION; ELECTRIC POTENTIAL; EMBRYO; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; AMINO ACID SEQUENCE; ANIMAL; CELL MEMBRANE POTENTIAL; CHEMISTRY; DRUG ANTAGONISM; ELECTROPHYSIOLOGY; ELECTROSTIMULATION; ISOMERISM; METABOLISM; MOLECULAR GENETICS; PATCH CLAMP; PHYSIOLOGY; RAT;

AMINO ACID SEQUENCE; ANIMALS; DESOXYCORTICOSTERONE; ELECTRIC STIMULATION; ELECTROPHYSIOLOGY; GABA ANTAGONISTS; GAMMA-AMINOBUTYRIC ACID; ISOMERISM; MEMBRANE POTENTIALS; MOLECULAR SEQUENCE DATA; NEUROTRANSMITTER AGENTS; PATCH-CLAMP TECHNIQUES; RATS; RECEPTORS, GABA-A; RECOMBINANT FUSION PROTEINS; RECOMBINANT PROTEINS;

EID: 0036707591     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0028-3908(02)00163-6     Document Type: Article

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