Differential anesthetic activity of ketamine and the GABAergic neurosteroid allopregnanolone in mice lacking progesterone receptor A and B subtypes

Methods and Findings in Experimental and Clinical Pharmacology

Volumn 29, Issue 10, 2007, Pages 659-664

  Reddy, Doodipala S ^a   Zeng, Y C ^a,b  

^a NORTH CAROLINA STATE UNIVERSITY   (United States)

^b MPI RESEARCH   (United States)

Author keywords

Allopregnanolone; Anesthesia; Neurosteroid; Progesterone receptor

Indexed keywords

3ALPHA HYDROXY 5ALPHA PREGNAN 20 ONE; 4 AMINOBUTYRIC ACID; KETAMINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; NEUROSTEROID; PROGESTERONE RECEPTOR A; PROGESTERONE RECEPTOR B;

ANESTHESIA; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG MECHANISM; DRUG POTENCY; DRUG RESPONSE; FEMALE; GENOTYPE; IMMUNOHISTOCHEMISTRY; MALE; MOUSE; NONHUMAN; SEDATION;

ANALGESICS; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GABA AGONISTS; GENOTYPE; IMMUNOCHEMISTRY; INJECTIONS, INTRAPERITONEAL; INJECTIONS, SUBCUTANEOUS; KETAMINE; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PREGNANOLONE; PROTEIN ISOFORMS; REACTION TIME; RECEPTORS, N-METHYL-D-ASPARTATE; RECEPTORS, PROGESTERONE; SEX FACTORS; STEREOISOMERISM;

EID: 39149107740     PISSN: 03790355     EISSN: None     Source Type: Journal    
DOI: 10.1358/mf.2007.29.10.1147766     Document Type: Article

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