-
1
-
-
61849157257
-
Alzheimer's disease
-
Burns A, Iliffe S. Alzheimer's disease. BMJ 2009; 338: b158.
-
(2009)
BMJ
, vol.338
-
-
Burns, A.1
Iliffe, S.2
-
2
-
-
84879305031
-
Epidemiology of Alzheimer Disease
-
doi: 10. 1101/cshperspect. a006239
-
Mayeux R, Stern Y. Epidemiology of Alzheimer Disease. Cold Spring Harb Perspect Med 2012; 2(8): doi: 10. 1101/cshperspect. a006239.
-
(2012)
Cold Spring Harb Perspect Med
, vol.2
, Issue.8
-
-
Mayeux, R.1
Stern, Y.2
-
4
-
-
0042508791
-
Neuropathologic changes in Alzheimer's disease
-
Wenk GL. Neuropathologic changes in Alzheimer's disease. J Clin Psychiatry 2003; 64: 7-10.
-
(2003)
J Clin Psychiatry
, vol.64
, pp. 7-10
-
-
Wenk, G.L.1
-
5
-
-
34648846362
-
Death receptor takes centre stage
-
Whalley K. Death receptor takes centre stage. Nat Rev Neurosci 2007; 8: 740-1.
-
(2007)
Nat Rev Neurosci
, vol.8
, pp. 740-741
-
-
Whalley, K.1
-
6
-
-
77950866465
-
Epigenetic regulation in the pathophysiology of Alzheimer's disease
-
Chouliaras L, Rutten BP, Kenis G, et al. Epigenetic regulation in the pathophysiology of Alzheimer's disease. Prog Neurobiol 2010; 90: 498-510.
-
(2010)
Prog Neurobiol
, vol.90
, pp. 498-510
-
-
Chouliaras, L.1
Rutten, B.P.2
Kenis, G.3
-
7
-
-
79958769568
-
Epigenetic mechanisms in Alzheimer's disease
-
Mastroeni D, Grover A, Delvaux E, Whiteside C, Coleman PD, Rogers J. Epigenetic mechanisms in Alzheimer's disease. Neurobiol Aging 2011; 32: 1161-80.
-
(2011)
Neurobiol Aging
, vol.32
, pp. 1161-1180
-
-
Mastroeni, D.1
Grover, A.2
Delvaux, E.3
Whiteside, C.4
Coleman, P.D.5
Rogers, J.6
-
8
-
-
0346786306
-
The emerging role of epigenetics in cellular and organismal aging
-
Bandyopadhyay D, Medrano EE. The emerging role of epigenetics in cellular and organismal aging. Exp Gerontol 2003; 38: 1299-307.
-
(2003)
Exp Gerontol
, vol.38
, pp. 1299-1307
-
-
Bandyopadhyay, D.1
Medrano, E.E.2
-
9
-
-
34447625911
-
Epigenetics and aging: The targets and the marks
-
Fraga MF, Esteller M. Epigenetics and aging: the targets and the marks. Trends Genet 2007; 23: 413-18.
-
(2007)
Trends Genet
, vol.23
, pp. 413-418
-
-
Fraga, M.F.1
Esteller, M.2
-
10
-
-
0344196937
-
Aging, cancer and nutrition: The DNA methylation connection
-
Liu L, Wylie RC, Andrews LG, Tollefsbol TO. Aging, cancer and nutrition: the DNA methylation connection. Mech Ageing Dev 2003; 124: 989-98.
-
(2003)
Mech Ageing Dev
, vol.124
, pp. 989-998
-
-
Liu, L.1
Wylie, R.C.2
Andrews, L.G.3
Tollefsbol, T.O.4
-
11
-
-
34247473478
-
The epigenetic basis of twin discordance in age-related diseases
-
Poulsen P, Esteller M, Vaag A, Fraga MF. The epigenetic basis of twin discordance in age-related diseases. Pediatr Res 2007; 61: 38R-42R.
-
(2007)
Pediatr Res
, vol.61
-
-
Poulsen, P.1
Esteller, M.2
Vaag, A.3
Fraga, M.F.4
-
12
-
-
0020638422
-
DNA methylation decreases in aging but not in immortal cells
-
Wilson VL, Jones PA. DNA methylation decreases in aging but not in immortal cells. Science 1983; 220: 1055-57.
-
(1983)
Science
, vol.220
, pp. 1055-1057
-
-
Wilson, V.L.1
Jones, P.A.2
-
13
-
-
38449106861
-
Reactivation of epigenetically silenced genes by DNA methyltransferase inhibitors: Basic concepts and clinical applications
-
Mund C, Brueckner B, Lyko F. Reactivation of epigenetically silenced genes by DNA methyltransferase inhibitors: basic concepts and clinical applications. Epigenetics 2006; 1: 7-13.
-
(2006)
Epigenetics
, vol.1
, pp. 7-13
-
-
Mund, C.1
Brueckner, B.2
Lyko, F.3
-
14
-
-
42449155119
-
The GNAS locus and pseudohypoparathyroidism
-
Bastepe M. The GNAS locus and pseudohypoparathyroidism. Adv Exp Med Biol 2008; 626: 27-40.
-
(2008)
Adv Exp Med Biol
, vol.626
, pp. 27-40
-
-
Bastepe, M.1
-
15
-
-
10044221016
-
Colorectal cancers in a new mouse model of familial adenomatous polyposis: Influence of genetic and environmental modifiers
-
Colnot S, Niwa-Kawakita M, Hamard G, et al. Colorectal cancers in a new mouse model of familial adenomatous polyposis: influence of genetic and environmental modifiers. Lab Invest 2004; 84: 1619-30.
-
(2004)
Lab Invest
, vol.84
, pp. 1619-1630
-
-
Colnot, S.1
Niwa-Kawakita, M.2
Hamard, G.3
-
16
-
-
0036392129
-
Epigenetic versus genetic alterations in the inactivation of E-cadherin
-
Strathdee G. Epigenetic versus genetic alterations in the inactivation of E-cadherin. Semin Cancer Biol 2002; 12: 373-9.
-
(2002)
Semin Cancer Biol
, vol.12
, pp. 373-379
-
-
Strathdee, G.1
-
17
-
-
0027376236
-
Pitfalls in the molecular genetic diagnosis of Leber hereditary optic neuropathy (LHON)
-
Johns DR, Neufeld MJ. Pitfalls in the molecular genetic diagnosis of Leber hereditary optic neuropathy (LHON). Am J Hum Genet 1993; 53: 916-20.
-
(1993)
Am J Hum Genet
, vol.53
, pp. 916-920
-
-
Johns, D.R.1
Neufeld, M.J.2
-
18
-
-
34447104563
-
Mutator pathways unleashed by epigenetic silencing in human cancer
-
Jacinto FV, Esteller M. Mutator pathways unleashed by epigenetic silencing in human cancer. Mutagenesis 2007; 22: 247-53.
-
(2007)
Mutagenesis
, vol.22
, pp. 247-253
-
-
Jacinto, F.V.1
Esteller, M.2
-
19
-
-
61549106928
-
Epigenetics and dermatological disease
-
Millington GW. Epigenetics and dermatological disease. Pharmacogenomics 2008; 9: 1835-50.
-
(2008)
Pharmacogenomics
, vol.9
, pp. 1835-1850
-
-
Millington, G.W.1
-
20
-
-
77957730965
-
Genome-wide association studies in Alzheimer's disease
-
Bertram L, Tanzi RE. Genome-wide association studies in Alzheimer's disease. Hum Mol Genet 2009; 18: R137-45.
-
(2009)
Hum Mol Genet
, vol.18
-
-
Bertram, L.1
Tanzi, R.E.2
-
21
-
-
78651266932
-
Autosomal-dominant Alzheimer's disease: A review and proposal for the prevention of Alzheimer's disease
-
Bateman RJ, Aisen PS, De Strooper B, et al. Autosomal-dominant Alzheimer's disease: a review and proposal for the prevention of Alzheimer's disease. Alzheimers Res Ther 2011; 3: 1.
-
(2011)
Alzheimers Res Ther
, vol.3
, pp. 1
-
-
Bateman, R.J.1
Aisen, P.S.2
De Strooper, B.3
-
22
-
-
26944475934
-
Molecular diagnosis of autosomal dominant early onset alzheimer's disease: An update
-
Raux G, Guyant-Maréchal L, Martin C, et al. Molecular diagnosis of autosomal dominant early onset alzheimer's disease: an update. J Med Genet 2005; 42: 793-95.
-
(2005)
J Med Genet
, vol.42
, pp. 793-795
-
-
Raux, G.1
Guyant-Maréchal, L.2
Martin, C.3
-
23
-
-
13944276825
-
Twenty years of the Alzheimer's disease amyloid hypothesis: A genetic perspective
-
Tanzi RE, Bertram L. Twenty years of the Alzheimer's disease amyloid hypothesis: a genetic perspective. Cell 2005; 120: 545-55.
-
(2005)
Cell
, vol.120
, pp. 545-555
-
-
Tanzi, R.E.1
Bertram, L.2
-
24
-
-
77957927865
-
The genetics of Alzheimer disease: Back to the future
-
Bertram L, Lill CM, Tanzi RE. The genetics of Alzheimer disease: back to the future. Neuron 2010; 68: 270-81.
-
(2010)
Neuron
, vol.68
, pp. 270-281
-
-
Bertram, L.1
Lill, C.M.2
Tanzi, R.E.3
-
25
-
-
33749177143
-
A hundred years of Alzheimer's disease research
-
Hardy J. A hundred years of Alzheimer's disease research. Neuron 2006; 52: 3-13.
-
(2006)
Neuron
, vol.52
, pp. 3-13
-
-
Hardy, J.1
-
26
-
-
77954122221
-
Genome-wide association studies: The key to unlocking neurodegeneration?
-
Gandhi S, Wood NW. Genome-wide association studies: the key to unlocking neurodegeneration? Nat Neurosci 2010; 13: 789-94.
-
(2010)
Nat Neurosci
, vol.13
, pp. 789-794
-
-
Gandhi, S.1
Wood, N.W.2
-
27
-
-
70349558522
-
Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease
-
Harold D, Abraham R, Hollingworth P, et al. Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease. Nat Genet 2009; 41: 1088-93.
-
(2009)
Nat Genet
, vol.41
, pp. 1088-1093
-
-
Harold, D.1
Abraham, R.2
Hollingworth, P.3
-
28
-
-
78549264026
-
Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease
-
Lambert JC, Heath S, Even G, et al. Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease. Nat Genet 2009; 41: 1094-99.
-
(2009)
Nat Genet
, vol.41
, pp. 1094-1099
-
-
Lambert, J.C.1
Heath, S.2
Even, G.3
-
29
-
-
77952307991
-
Genome-wide analysis of genetic loci associated with Alzheimer disease
-
Seshadri S, Fitzpatrick AL, Ikram MA, et al. Genome-wide analysis of genetic loci associated with Alzheimer disease. JAMA 2010; 303: 1832-40.
-
(2010)
JAMA
, vol.303
, pp. 1832-1840
-
-
Seshadri, S.1
Fitzpatrick, A.L.2
Ikram, M.A.3
-
30
-
-
79955484414
-
Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease
-
Hollingworth P, Harold D, Sims R, et al. Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease. Nat Genet 2011; 43: 429-35.
-
(2011)
Nat Genet
, vol.43
, pp. 429-435
-
-
Hollingworth, P.1
Harold, D.2
Sims, R.3
-
31
-
-
79955464911
-
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset alzheimer's disease
-
Naj AC, Jun G, Beecham GW, et al. Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset alzheimer's disease. Nat Genet 2011; 43: 436-41.
-
(2011)
Nat Genet
, vol.43
, pp. 436-441
-
-
Naj, A.C.1
Jun, G.2
Beecham, G.W.3
-
32
-
-
0037315878
-
A critical analysis of new molecular targets and strategies for drug developments in Alzheimer's disease
-
Lahiri DK, Farlow MR, Sambamurti K, Greig NH, Giacobini E, Schneider LS. A critical analysis of new molecular targets and strategies for drug developments in Alzheimer's disease. Curr Drug Targets 2003; 4: 97-112.
-
(2003)
Curr Drug Targets
, vol.4
, pp. 97-112
-
-
Lahiri, D.K.1
Farlow, M.R.2
Sambamurti, K.3
Greig, N.H.4
Giacobini, E.5
Schneider, L.S.6
-
34
-
-
58149506264
-
Depression in the prodromal phase of Alzheimer disease and the reverse causal hypothesis
-
Modrego PJ. Depression in the prodromal phase of Alzheimer disease and the reverse causal hypothesis. Arch Gen Psychiatry 2009; 66: 107.
-
(2009)
Arch Gen Psychiatry
, vol.66
, pp. 107
-
-
Modrego, P.J.1
-
35
-
-
4043179916
-
Depression in patients with mild cognitive impairment increases the risk of developing dementia of Alzheimer type: A prospective cohort study
-
Modrego PJ, Ferrandez J. Depression in patients with mild cognitive impairment increases the risk of developing dementia of Alzheimer type: a prospective cohort study. Arch Neurol 2004; 61: 1290-93.
-
(2004)
Arch Neurol
, vol.61
, pp. 1290-1293
-
-
Modrego, P.J.1
Ferrandez, J.2
-
36
-
-
0032787320
-
Traumatic brain injury in young, amyloid-beta peptide overexpressing transgenic mice induces marked ipsilateral hippocampal atrophy and diminished Abeta deposition during aging
-
Nakagawa Y, Nakamura M, McIntosh TK, et al. Traumatic brain injury in young, amyloid-beta peptide overexpressing transgenic mice induces marked ipsilateral hippocampal atrophy and diminished Abeta deposition during aging. J Comp Neurol 1999; 411: 390-8.
-
(1999)
J Comp Neurol
, vol.411
, pp. 390-398
-
-
Nakagawa, Y.1
Nakamura, M.2
McIntosh, T.K.3
-
37
-
-
0034068261
-
Brain trauma in aged transgenic mice induces regression of established abeta deposits
-
Nakagawa, Y., Reed, L., Nakamura, M, et al. Brain trauma in aged transgenic mice induces regression of established abeta deposits. Exp Neurol 2000; 163: 244-52.
-
(2000)
Exp Neurol
, vol.163
, pp. 244-252
-
-
Nakagawa, Y.1
Reed, L.2
Nakamura, M.3
-
38
-
-
33749528834
-
Chronic psychological distress and risk of Alzheimer's disease in old age
-
Wilson RS, Arnold SE, Schneider JA, Kelly JF, Tang Y, Bennett DA. Chronic psychological distress and risk of Alzheimer's disease in old age. Neuroepidemiology 2006; 27: 143-53.
-
(2006)
Neuroepidemiology
, vol.27
, pp. 143-153
-
-
Wilson, R.S.1
Arnold, S.E.2
Schneider, J.A.3
Kelly, J.F.4
Tang, Y.5
Bennett, D.A.6
-
39
-
-
38149024924
-
Alzheimer's disease (AD)-like pathology in aged monkeys after infantile exposure to environmental metal lead (Pb): Evidence for a developmental origin and environmental link for AD
-
Wu J, Basha, MR, Brock B, et al. Alzheimer's disease (AD)-like pathology in aged monkeys after infantile exposure to environmental metal lead (Pb): evidence for a developmental origin and environmental link for AD. J. Neurosci 2008; 28: 3-9.
-
(2008)
J Neurosci
, vol.28
, pp. 3-9
-
-
Wu, J.1
Basha, M.R.2
Brock, B.3
-
40
-
-
68849119553
-
Physical activity, diet, and risk of Alzheimer disease
-
Scarmeas N, Luchsinger JA, Schupf N, et al. Physical activity, diet, and risk of Alzheimer disease. JAMA 2009; 302: 627-37.
-
(2009)
JAMA
, vol.302
, pp. 627-637
-
-
Scarmeas, N.1
Luchsinger, J.A.2
Schupf, N.3
-
41
-
-
84859001154
-
Association between mid-life marital status and cognitive function in later life: Population based cohort study
-
Hakansson K, Rovio S, Helkala EL, et al. Association between mid-life marital status and cognitive function in later life: population based cohort study. BMJ 2009; 339: b2462.
-
(2009)
BMJ
, vol.339
-
-
Hakansson, K.1
Rovio, S.2
Helkala, E.L.3
-
42
-
-
49049122193
-
Alzheimer's disease and vascular dementia in developing countries: Prevalence, management, and risk factors
-
Kalaria RN, Maestre GE, Arizaga R, et al. Alzheimer's disease and vascular dementia in developing countries: prevalence, management, and risk factors. Lancet Neurol 2008; 7: 812-26.
-
(2008)
Lancet Neurol
, vol.7
, pp. 812-826
-
-
Kalaria, R.N.1
Maestre, G.E.2
Arizaga, R.3
-
44
-
-
54249166128
-
Gene-environment interactions in schizophrenia: Review of epidemiological findings and future directions
-
van Os J, Rutten BP, Poulton R. Gene-environment interactions in schizophrenia: review of epidemiological findings and future directions. Schizophr Bull 2008; 34: 1066-82.
-
(2008)
Schizophr Bull
, vol.34
, pp. 1066-1082
-
-
van Os, J.1
Rutten, B.P.2
Poulton, R.3
-
45
-
-
69949099211
-
Gene-environment-wide interaction studies in psychiatry
-
van Os J, Rutten BP. Gene-environment-wide interaction studies in psychiatry. Am J Psychiatry 2009; 166: 964-6.
-
(2009)
Am J Psychiatry
, vol.166
, pp. 964-966
-
-
van Os, J.1
Rutten, B.P.2
-
46
-
-
2442684094
-
Cholesterol and APOE genotype interact to influence Alzheimer disease progression
-
Evans RM, Hui S, Perkins A, Lahiri DK, Poirier J, Farlow MR. Cholesterol and APOE genotype interact to influence Alzheimer disease progression. Neurology 2004; 62: 1869-71.
-
(2004)
Neurology
, vol.62
, pp. 1869-1871
-
-
Evans, R.M.1
Hui, S.2
Perkins, A.3
Lahiri, D.K.4
Poirier, J.5
Farlow, M.R.6
-
47
-
-
33645808672
-
Apolipoprotein E4: A causative factor and therapeutic target in neuropathology, including Alzheimer's disease
-
Mahley RW, Weisgraber KH, Huang Y. Apolipoprotein E4: a causative factor and therapeutic target in neuropathology, including Alzheimer's disease. Proc Natl Acad Sci USA 2006; 103: 5644-51.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 5644-5651
-
-
Mahley, R.W.1
Weisgraber, K.H.2
Huang, Y.3
-
48
-
-
0030893280
-
The role of heredity in lateonset alzheimer disease and vascular dementia. A twin study
-
Bergem AL, Engedal K, Kringlen E. The role of heredity in lateonset alzheimer disease and vascular dementia. A twin study. Arch Gen Psychiatry 1997; 54: 264-70.
-
(1997)
Arch Gen Psychiatry
, vol.54
, pp. 264-270
-
-
Bergem, A.L.1
Engedal, K.2
Kringlen, E.3
-
49
-
-
0029113637
-
Alzheimer's disease in the National Academy of Sciences-National Research Council Registry of Aging Twin Veterans. III. Detection of cases, longitudinal results, and observations on twin concordance
-
Breitner JC, Welsh KA, Gau BA, et al. Alzheimer's disease in the National Academy of Sciences-National Research Council Registry of Aging Twin Veterans. III. Detection of cases, longitudinal results, and observations on twin concordance. Arch. Neurol 1995; 52: 763-71.
-
(1995)
Arch Neurol
, vol.52
, pp. 763-771
-
-
Breitner, J.C.1
Welsh, K.A.2
Gau, B.A.3
-
50
-
-
0030823158
-
Effects of age, sex, and ethnicity on the association between Apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium
-
Farrer LA, Cupples LA, Haines JL, et al. Effects of age, sex, and ethnicity on the association between Apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium. JAMA 1997; 278: 1349-56.
-
(1997)
JAMA
, vol.278
, pp. 1349-1356
-
-
Farrer, L.A.1
Cupples, L.A.2
Haines, J.L.3
-
51
-
-
32244435907
-
Role of genes and environments for explaining Alzheimer disease
-
Gatz M, Reynolds CA, Fratiglioni L. Role of genes and environments for explaining Alzheimer disease. Arch. Gen. Psychiatry 2006; 63: 168-74.
-
(2006)
Arch. Gen. Psychiatry
, vol.63
, pp. 168-174
-
-
Gatz, M.1
Reynolds, C.A.2
Fratiglioni, L.3
-
52
-
-
0029948979
-
Dementia in twins
-
Raiha I, Kaprio J, Koskenvuo M, Rajala T, Sourander L. Dementia in twins. Lancet 1996; 347: 1706.
-
(1996)
Lancet
, vol.347
, pp. 1706
-
-
Raiha, I.1
Kaprio, J.2
Koskenvuo, M.3
Rajala, T.4
Sourander, L.5
-
53
-
-
34848839240
-
Clinic pathological concordance and discordance in three monozygotic twin pairs with familial Alzheimer's disease
-
Brickell KL, Leverenz JB, Steinbart EJ, et al. Clinic pathological concordance and discordance in three monozygotic twin pairs with familial Alzheimer's disease. J Neurol Neurosurg Psychiatry 2007; 78: 1050-5.
-
(2007)
J Neurol Neurosurg Psychiatry
, vol.78
, pp. 1050-1055
-
-
Brickell, K.L.1
Leverenz, J.B.2
Steinbart, E.J.3
-
54
-
-
23044514669
-
Epigenetic differences arise during the lifetime of monozygotic twins
-
Fraga MF, Ballestar E, Paz MF, et al. Epigenetic differences arise during the lifetime of monozygotic twins. Proc Natl Acad Sci USA 2005; 102: 10604-9.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 10604-10609
-
-
Fraga, M.F.1
Ballestar, E.2
Paz, M.F.3
-
55
-
-
11844257540
-
Complete ascertainment of dementia in the Swedish Twin Registry: The HARMONY study
-
Gatz M, Fratiglioni L, Johansson B, et al. Complete ascertainment of dementia in the Swedish Twin Registry: the HARMONY study. Neurobiol Aging 2005; 26: 439-47.
-
(2005)
Neurobiol Aging
, vol.26
, pp. 439-447
-
-
Gatz, M.1
Fratiglioni, L.2
Johansson, B.3
-
56
-
-
33745752370
-
Epigenetics and twins: Three variations on the theme
-
Petronis A. Epigenetics and twins: three variations on the theme. Trends Genet 2006; 22: 347-50.
-
(2006)
Trends Genet
, vol.22
, pp. 347-350
-
-
Petronis, A.1
-
57
-
-
33847095134
-
Complex disease, gender and epigenetics
-
Kaminsky Z, Wang SC, Petronis A. Complex disease, gender and epigenetics. Ann Med 2006; 38: 530-44.
-
(2006)
Ann Med
, vol.38
, pp. 530-544
-
-
Kaminsky, Z.1
Wang, S.C.2
Petronis, A.3
-
58
-
-
49949108971
-
Age-specific epigenetic drift in late onset alzheimer's disease
-
Wang SC, Oelze B, Schumacher A. Age-specific epigenetic drift in late onset alzheimer's disease. PLoS ONE 2008; 3: e2698.
-
(2008)
PLoS ONE
, vol.3
-
-
Wang, S.C.1
Oelze, B.2
Schumacher, A.3
-
59
-
-
2142814375
-
Methylomics in psychiatry: Modulation of gene-environment interactions may be through DNA methylation
-
Abdolmaleky HM, Smith CL, Faraone SV, et al. Methylomics in psychiatry: modulation of gene-environment interactions may be through DNA methylation. Am J Med Genet B: Neuropsychiatr Genet 2004; 127B: 51-9.
-
(2004)
Am J Med Genet B: Neuropsychiatr Genet
, vol.127 B
, pp. 51-59
-
-
Abdolmaleky, H.M.1
Smith, C.L.2
Faraone, S.V.3
-
60
-
-
44449134663
-
Gene-environment interactions and epigenetic basis of human diseases
-
Liu L, Li Y, Tollefsbol TO. Gene-environment interactions and epigenetic basis of human diseases. Curr Issues Mol Biol 2008; 10: 25-36.
-
(2008)
Curr Issues Mol Biol
, vol.10
, pp. 25-36
-
-
Liu, L.1
Li, Y.2
Tollefsbol, T.O.3
-
61
-
-
68149183508
-
Genetic and epigenetic regulation of aging
-
Fraga MF. Genetic and epigenetic regulation of aging. Curr Opin Immunol 2009; 21: 446-53.
-
(2009)
Curr Opin Immunol
, vol.21
, pp. 446-453
-
-
Fraga, M.F.1
-
62
-
-
31944432339
-
A genome-wide analysis of CpG dinucleotides in the human genome distinguishes two distinct classes of promoters
-
Saxonov S, Berg P, Brutlag DL. A genome-wide analysis of CpG dinucleotides in the human genome distinguishes two distinct classes of promoters. Proc Natl Acad Sci USA 2006; 103: 1412-17.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 1412-1417
-
-
Saxonov, S.1
Berg, P.2
Brutlag, D.L.3
-
63
-
-
0018225693
-
The occurrence and transmission of a pattern of DNA methylation in Xenopus laevis ribosomal DNA
-
Bird AP. The occurrence and transmission of a pattern of DNA methylation in Xenopus laevis ribosomal DNA. Philos Trans R Soc Lond B Biol Sci 1978; 283: 325-7.
-
(1978)
Philos Trans R Soc Lond B Biol Sci
, vol.283
, pp. 325-327
-
-
Bird, A.P.1
-
64
-
-
0141706713
-
The eukaryotic DNMT2 genes encode a new class of cytosine-5 DNA methyltransferases
-
Tang LY, Reddy MN, Rasheva V, et al. The eukaryotic DNMT2 genes encode a new class of cytosine-5 DNA methyltransferases. J Biol Chem 2003; 278: 33613-6.
-
(2003)
J Biol Chem
, vol.278
, pp. 33613-33616
-
-
Tang, L.Y.1
Reddy, M.N.2
Rasheva, V.3
-
65
-
-
0035863850
-
Structure of human DNMT2, an enigmatic DNA methyltransferase homolog that displays denaturant-resistant binding to DNA
-
Dong A, Yoder JA, Zhang X, Zhou L, Bestor TH, Cheng X. Structure of human DNMT2, an enigmatic DNA methyltransferase homolog that displays denaturant-resistant binding to DNA. Nucleic Acids Res 2001; 29: 439-48.
-
(2001)
Nucleic Acids Res
, vol.29
, pp. 439-448
-
-
Dong, A.1
Yoder, J.A.2
Zhang, X.3
Zhou, L.4
Bestor, T.H.5
Cheng, X.6
-
66
-
-
77953728422
-
One-carbon metabolism and Alzheimer's disease: Focus on epigenetics
-
Coppedè F. One-carbon metabolism and Alzheimer's disease: focus on epigenetics. Curr Genomics 2010; 11: 246-60.
-
(2010)
Curr Genomics
, vol.11
, pp. 246-260
-
-
Coppedè, F.1
-
67
-
-
33751505540
-
DNA methylation profiling of human chromosomes 6, 20 and 22
-
Eckhardt F, Lewin J, Cortese R, et al. DNA methylation profiling of human chromosomes 6, 20 and 22. Nat Genet 2006; 38: 1378-85.
-
(2006)
Nat Genet
, vol.38
, pp. 1378-1385
-
-
Eckhardt, F.1
Lewin, J.2
Cortese, R.3
-
68
-
-
34047116826
-
Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome
-
Weber M, Hellmann I, Stadler MB, et al. Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome. Nat Genet 2007; 39: 457-66.
-
(2007)
Nat Genet
, vol.39
, pp. 457-466
-
-
Weber, M.1
Hellmann, I.2
Stadler, M.B.3
-
69
-
-
59149084538
-
The human colon cancer methylome shows similar hypo-and hypermethylation at conserved tissuespecific CpG island shores
-
Irizarry RA, Ladd-Acosta C, Wen B, et al. The human colon cancer methylome shows similar hypo-and hypermethylation at conserved tissuespecific CpG island shores. Nat Genet 2009; 41: 178-86.
-
(2009)
Nat Genet
, vol.41
, pp. 178-186
-
-
Irizarry, R.A.1
Ladd-Acosta, C.2
Wen, B.3
-
70
-
-
66149123748
-
The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain
-
Kriaucionis S, Heintz N. The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain. Science 2009; 324: 929-30.
-
(2009)
Science
, vol.324
, pp. 929-930
-
-
Kriaucionis, S.1
Heintz, N.2
-
71
-
-
66149146320
-
Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1
-
Tahiliani M, Koh KP, Shen Y, et al. Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1. Science 2009; 324: 930-5.
-
(2009)
Science
, vol.324
, pp. 930-935
-
-
Tahiliani, M.1
Koh, K.P.2
Shen, Y.3
-
72
-
-
33847055935
-
Endogenous cytosine damage products alter the site selectivity of human DNA maintenance methyltransferase DNMT1
-
Valinluck V, Sowers LC. Endogenous cytosine damage products alter the site selectivity of human DNA maintenance methyltransferase DNMT1. Cancer Res 2007; 67: 946-50.
-
(2007)
Cancer Res
, vol.67
, pp. 946-950
-
-
Valinluck, V.1
Sowers, L.C.2
-
73
-
-
4043112183
-
Oxidative damage to methyl-CpG sequences inhibits the binding of the methyl-CpG binding domain (MBD) of methyl-CpG binding protein 2 (MeCP2)
-
Valinluck V, Tsai HH, Rogstad DK, Burdzy A, Bird A, Sowers LC. Oxidative damage to methyl-CpG sequences inhibits the binding of the methyl-CpG binding domain (MBD) of methyl-CpG binding protein 2 (MeCP2). Nucleic Acids Res 2004; 32: 4100-8.
-
(2004)
Nucleic Acids Res
, vol.32
, pp. 4100-4108
-
-
Valinluck, V.1
Tsai, H.H.2
Rogstad, D.K.3
Burdzy, A.4
Bird, A.5
Sowers, L.C.6
-
74
-
-
0013857650
-
Structural modifications of histones and their possible role in the regulation of ribonucleic acid synthesis
-
Allfrey VG. Structural modifications of histones and their possible role in the regulation of ribonucleic acid synthesis. Proc Can Cancer Conf 1966; 6: 313-35.
-
(1966)
Proc Can Cancer Conf
, vol.6
, pp. 313-335
-
-
Allfrey, V.G.1
-
75
-
-
0033601073
-
Methylation-induced repression--belts, braces, and chromatin
-
Bird AP, Wolffe AP. Methylation-induced repression--belts, braces, and chromatin. Cell 1999; 99: 451-4.
-
(1999)
Cell
, vol.99
, pp. 451-454
-
-
Bird, A.P.1
Wolffe, A.P.2
-
76
-
-
0031837109
-
Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription
-
Jones PL, Veenstra GJ, Wade PA, et al. Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription. Nat Genet 1998; 19: 187-91.
-
(1998)
Nat Genet
, vol.19
, pp. 187-191
-
-
Jones, P.L.1
Veenstra, G.J.2
Wade, P.A.3
-
77
-
-
0035542974
-
Methyl CpG-binding proteins and transcriptional repression
-
Wade PA. Methyl CpG-binding proteins and transcriptional repression. Bioassays 2001; 23: 1131-7.
-
(2001)
Bioassays
, vol.23
, pp. 1131-1137
-
-
Wade, P.A.1
-
78
-
-
0035312289
-
The MeCP1 complex represses transcription through preferential binding, remodeling, and deacetylating methylated nucleosomes
-
Feng Q, Zhang Y. The MeCP1 complex represses transcription through preferential binding, remodeling, and deacetylating methylated nucleosomes. Genes Dev 2001; 15: 827-32.
-
(2001)
Genes Dev
, vol.15
, pp. 827-832
-
-
Feng, Q.1
Zhang, Y.2
-
79
-
-
55849109584
-
The epigenetics of rRNA genes: From molecular to chromosome biology
-
McStay B, Grummt I. The epigenetics of rRNA genes: from molecular to chromosome biology. Annu Rev Cell Dev Biol 2008; 24: 131-57.
-
(2008)
Annu Rev Cell Dev Biol
, vol.24
, pp. 131-157
-
-
McStay, B.1
Grummt, I.2
-
80
-
-
42949086521
-
Approaches for studying microRNA and small interfering RNA methylation in vitro and in vivo
-
Yang Z, Vilkaitis G, Yu B, Klimasauskas S, Chen X. Approaches for studying microRNA and small interfering RNA methylation in vitro and in vivo. Meth Enzymol 2007; 427: 139-54.
-
(2007)
Meth Enzymol
, vol.427
, pp. 139-154
-
-
Yang, Z.1
Vilkaitis, G.2
Yu, B.3
Klimasauskas, S.4
Chen, X.5
-
82
-
-
0037444803
-
Histone deacetylases (HDACs): Characterization of the classical HDAC family
-
de Ruijter AJ, van Gennip AH, Caron HN, Kemp S, van Kuilenburg AB. Histone deacetylases (HDACs): characterization of the classical HDAC family. Biochem J 2003; 370: 737-49.
-
(2003)
Biochem J
, vol.370
, pp. 737-749
-
-
de Ruijter, A.J.1
van Gennip, A.H.2
Caron, H.N.3
Kemp, S.4
van Kuilenburg, A.B.5
-
83
-
-
34547864236
-
Histone deacetylase inhibitors: Molecular mechanisms of action
-
Xu WS, Parmigiani RB, Marks PA. Histone deacetylase inhibitors: molecular mechanisms of action. Oncogene 2007; 26: 5541-52.
-
(2007)
Oncogene
, vol.26
, pp. 5541-5552
-
-
Xu, W.S.1
Parmigiani, R.B.2
Marks, P.A.3
-
84
-
-
38649124003
-
Epigenetic targets of HDAC inhibition in neurodegenerative and psychiatric disorders
-
Abel T, Zukin RS. Epigenetic targets of HDAC inhibition in neurodegenerative and psychiatric disorders. Curr Opin Pharmacol 2008; 8: 57-64.
-
(2008)
Curr Opin Pharmacol
, vol.8
, pp. 57-64
-
-
Abel, T.1
Zukin, R.S.2
-
85
-
-
13344259297
-
Valproic acid: How it works. Or not
-
Lagace DC, O'Brien WT, Gurvich N, Nachtigal MW, Klein PS. Valproic acid: how it works. Or not. Clin Neur Res 2004; 4: 215-25.
-
(2004)
Clin Neur Res
, vol.4
, pp. 215-225
-
-
Lagace, D.C.1
O'Brien, W.T.2
Gurvich, N.3
Nachtigal, M.W.4
Klein, P.S.5
-
86
-
-
21744444434
-
Evolving anticancer drug valproic acid: Insights into the mechanism and clinical studies
-
Blaheta RA, Michaelis M, Driever PH, Cinatl J Jr. Evolving anticancer drug valproic acid: insights into the mechanism and clinical studies. Med Res Rev 2005; 25: 383-97.
-
(2005)
Med Res Rev
, vol.25
, pp. 383-397
-
-
Blaheta, R.A.1
Michaelis, M.2
Driever, P.H.3
Cinatl Jr., J.4
-
87
-
-
18244383806
-
Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells
-
Gottlicher M, Minucci S, Zhu P, et al. Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells. EMBO J 2001; 20: 6969-78.
-
(2001)
EMBO J
, vol.20
, pp. 6969-6978
-
-
Gottlicher, M.1
Minucci, S.2
Zhu, P.3
-
88
-
-
0035965343
-
Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen
-
Phiel CJ, Zhang F, Huang EY, Guenther MG, Lazar MA, Klein PS. Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen. J Biol Chem 2001; 276: 36734-41.
-
(2001)
J Biol Chem
, vol.276
, pp. 36734-36741
-
-
Phiel, C.J.1
Zhang, F.2
Huang, E.Y.3
Guenther, M.G.4
Lazar, M.A.5
Klein, P.S.6
-
89
-
-
33745226457
-
Valproic acid induces caspase 3-mediated apoptosis in microglial cells
-
Dragunow M, Greenwood JM, Cameron RE, et al. Valproic acid induces caspase 3-mediated apoptosis in microglial cells. Neuroscience 2006; 140: 1149-56.
-
(2006)
Neuroscience
, vol.140
, pp. 1149-1156
-
-
Dragunow, M.1
Greenwood, J.M.2
Cameron, R.E.3
-
90
-
-
33845296450
-
Valproate protects dopaminergic neurons in midbrain neuron/glia cultures by stimulating the release of neurotrophic factors from astrocytes
-
Chen PS, Peng GS, Li G, et al. Valproate protects dopaminergic neurons in midbrain neuron/glia cultures by stimulating the release of neurotrophic factors from astrocytes. Mol Psychiatry 2006; 11: 1116-25.
-
(2006)
Mol Psychiatry
, vol.11
, pp. 1116-1125
-
-
Chen, P.S.1
Peng, G.S.2
Li, G.3
-
91
-
-
34248530339
-
Histone deacetylase inhibitors exhibit anti-inflammatory and neuroprotective effects in a rat permanent ischemic model of stroke: Multiple mechanisms of action
-
Kim HJ, Rowe M, Ren M, Hong JS, Chen PS, Chuang DM. Histone deacetylase inhibitors exhibit anti-inflammatory and neuroprotective effects in a rat permanent ischemic model of stroke: multiple mechanisms of action. J Pharmacol Exp Ther 2007; 321: 892-901.
-
(2007)
J Pharmacol Exp Ther
, vol.321
, pp. 892-901
-
-
Kim, H.J.1
Rowe, M.2
Ren, M.3
Hong, J.S.4
Chen, P.S.5
Chuang, D.M.6
-
92
-
-
55549129648
-
Histone deacetylase inhibitors upregulate astrocyte GDNF and BDNF gene transcription and protect dopaminergic neurons
-
Wu X, Chen PS, Dallas S, et al. Histone deacetylase inhibitors upregulate astrocyte GDNF and BDNF gene transcription and protect dopaminergic neurons. Int J Neuropsychopharmacol 2008; 11: 1123-34.
-
(2008)
Int J Neuropsychopharmacol
, vol.11
, pp. 1123-1134
-
-
Wu, X.1
Chen, P.S.2
Dallas, S.3
-
93
-
-
0042346416
-
Valproate induces replicationindependent active DNA demethylation
-
Detich N, Bovenzi V, Szyf M. Valproate induces replicationindependent active DNA demethylation. J Biol Chem 2003; 278: 27586-92.
-
(2003)
J Biol Chem
, vol.278
, pp. 27586-27592
-
-
Detich, N.1
Bovenzi, V.2
Szyf, M.3
-
94
-
-
34248370579
-
Histone hyperacetylation induces demethylation of reelin and 67-kDa glutamic acid de carboxylase promoters
-
Dong E, Guidotti A, Grayson DR, Costa E. Histone hyperacetylation induces demethylation of reelin and 67-kDa glutamic acid de carboxylase promoters. Proc Natl Acad Sci USA 2007; 104: 4676-81.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 4676-4681
-
-
Dong, E.1
Guidotti, A.2
Grayson, D.R.3
Costa, E.4
-
96
-
-
58849158388
-
How does SIRT1 affect metabolism, senescence and cancer?
-
Brooks CL, Gu W. How does SIRT1 affect metabolism, senescence and cancer? Nat Rev Cancer 2009; 9: 123-8.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 123-128
-
-
Brooks, C.L.1
Gu, W.2
-
97
-
-
0028149224
-
Maternal hyperhomocysteinemia: A risk factor for neural-tube defects?
-
Steegers-Theunissen RP, Boers GH, Trijbels FJ, et al. Maternal hyperhomocysteinemia: a risk factor for neural-tube defects? Metabolism 1994; 43: 1475-80.
-
(1994)
Metabolism
, vol.43
, pp. 1475-1480
-
-
Steegers-Theunissen, R.P.1
Boers, G.H.2
Trijbels, F.J.3
-
98
-
-
0028863219
-
Folate levels and neural tube defects. Implications for prevention
-
Daly LE, Kirke PN, Molloy A, Weir DG, Scott JM. Folate levels and neural tube defects. Implications for prevention. JAMA 1995; 274: 1698-702.
-
(1995)
JAMA
, vol.274
, pp. 1698-1702
-
-
Daly, L.E.1
Kirke, P.N.2
Molloy, A.3
Weir, D.G.4
Scott, J.M.5
-
99
-
-
0036861629
-
DNA methyltransferase inhibitors-state of the art
-
Goffin J, Eisenhauer E. DNA methyltransferase inhibitors-state of the art. Ann Oncol 2002; 13: 1699-716.
-
(2002)
Ann Oncol
, vol.13
, pp. 1699-1716
-
-
Goffin, J.1
Eisenhauer, E.2
-
100
-
-
0000929807
-
Nucleic acids components and their analogues. LI. Synthesis of 1-glycosyl derivatives of 5-azauracil and 5-azacytosine
-
Piskala A, Sorm F. Nucleic acids components and their analogues. LI. Synthesis of 1-glycosyl derivatives of 5-azauracil and 5-azacytosine. Coll Czeck Chem Commun 1964; 29: 2060-76.
-
(1964)
Coll Czeck Chem Commun
, vol.29
, pp. 2060-2076
-
-
Piskala, A.1
Sorm, F.2
-
101
-
-
0000929806
-
Synthesis of 2'-deoxy-D-ribofuranosyl-5-azacytosine
-
Pliml J, Sorm F. Synthesis of 2'-deoxy-D-ribofuranosyl-5-azacytosine. Coll Czeck Chem Commun 1964; 29: 2576-7.
-
(1964)
Coll Czeck Chem Commun
, vol.29
, pp. 2576-2577
-
-
Pliml, J.1
Sorm, F.2
-
102
-
-
0034105545
-
DNA methylation inhibitors in the treatment of leukemias, myelodysplastic syndromes and hemoglobinopathies: Clinical results and possible mechanisms of action
-
Lubbert M. DNA methylation inhibitors in the treatment of leukemias, myelodysplastic syndromes and hemoglobinopathies: clinical results and possible mechanisms of action. Curr Top Microbiol Immunol 2000; 249: 135-64.
-
(2000)
Curr Top Microbiol Immunol
, vol.249
, pp. 135-164
-
-
Lubbert, M.1
-
103
-
-
0035799382
-
Changes in DNA methylation in neoplasia: Pathophysiology and therapeutic implications
-
Santini V, Kantarjian HM, Issa JP. Changes in DNA methylation in neoplasia: pathophysiology and therapeutic implications. Ann Intern Med 2001; 134: 573-86.
-
(2001)
Ann Intern Med
, vol.134
, pp. 573-586
-
-
Santini, V.1
Kantarjian, H.M.2
Issa, J.P.3
-
104
-
-
0028151343
-
Toxicity of 5-aza-2'-deoxycytidine to mammalian cells is mediated primarily by covalent trapping of DNA methyltransferase rather than DNA demethylation
-
Juttermann R, Li E, Jaenisch R. Toxicity of 5-aza-2'-deoxycytidine to mammalian cells is mediated primarily by covalent trapping of DNA methyltransferase rather than DNA demethylation. Proc Natl Acad Sci USA 1994; 91: 11797-801.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 11797-11801
-
-
Juttermann, R.1
Li, E.2
Jaenisch, R.3
-
105
-
-
0020541275
-
Incorporation of 5-aza-2'-deoxycytidine-5β-triphosphate into DNA. Interactions with mammalian DNA polymerase alpha and DNA methylase
-
Bouchard J, Momparler RL. Incorporation of 5-aza-2'-deoxycytidine-5β-triphosphate into DNA. Interactions with mammalian DNA polymerase alpha and DNA methylase. Mol Pharmacol 1983; 24: 109-14.
-
(1983)
Mol Pharmacol
, vol.24
, pp. 109-114
-
-
Bouchard, J.1
Momparler, R.L.2
-
106
-
-
0020582853
-
On the mechanism of inhibition of DNA-cytosine methyltransferases by cytosine analogs
-
Santi DV, Garrett CE, Barr PJ. On the mechanism of inhibition of DNA-cytosine methyltransferases by cytosine analogs. Cell 1983; 33: 9-10.
-
(1983)
Cell
, vol.33
, pp. 9-10
-
-
Santi, D.V.1
Garrett, C.E.2
Barr, P.J.3
-
107
-
-
0019856151
-
High-performance liquid chromatographic analysis of chemical stability of 5-aza-2'-deoxycytidine
-
Lin KT, Momparler RL, Rivard GE. High-performance liquid chromatographic analysis of chemical stability of 5-aza-2'-deoxycytidine. J Pharm Sci 1981; 70: 1228-32.
-
(1981)
J Pharm Sci
, vol.70
, pp. 1228-1232
-
-
Lin, K.T.1
Momparler, R.L.2
Rivard, G.E.3
-
108
-
-
0021824184
-
DNA alkalilabile sites induced by incorporation of 5-aza-2'-deoxycytidine into DNA of mouse leukemia L1210 cells
-
D'Incalci M, Covey JM, Zaharko DS, Kohn KW. DNA alkalilabile sites induced by incorporation of 5-aza-2'-deoxycytidine into DNA of mouse leukemia L1210 cells. Cancer Res 1985; 45: 3197-202.
-
(1985)
Cancer Res
, vol.45
, pp. 3197-3202
-
-
D'Incalci, M.1
Covey, J.M.2
Zaharko, D.S.3
Kohn, K.W.4
-
109
-
-
0031964055
-
Inhibition of DNA methylation by 5-aza-2'-deoxycytidine suppresses the growth of human tumor cell lines
-
Bender CM, Pao MM, Jones PA. Inhibition of DNA methylation by 5-aza-2'-deoxycytidine suppresses the growth of human tumor cell lines. Cancer Res 1998; 58: 95-101.
-
(1998)
Cancer Res
, vol.58
, pp. 95-101
-
-
Bender, C.M.1
Pao, M.M.2
Jones, P.A.3
-
110
-
-
0027229492
-
Effects of 5-aza-2'-deoxycytidine on differentiation and oncogene expression in the human monoblastic leukemia cell line U-937
-
Attadia V. Effects of 5-aza-2'-deoxycytidine on differentiation and oncogene expression in the human monoblastic leukemia cell line U-937. Leukemia 1993; 7: 9-16.
-
(1993)
Leukemia
, vol.7
, pp. 9-16
-
-
Attadia, V.1
-
112
-
-
0034722899
-
Potential roles of antisense technology in cancer chemotherapy
-
Crooke ST. Potential roles of antisense technology in cancer chemotherapy. Oncogene 2000; 19: 6651-9.
-
(2000)
Oncogene
, vol.19
, pp. 6651-6659
-
-
Crooke, S.T.1
-
113
-
-
0028964323
-
Expression of antisense to DNA methyltransferase mRNA induces DNA demethylation and inhibits tumorigenesis
-
MacLeod AR, Szyf M. Expression of antisense to DNA methyltransferase mRNA induces DNA demethylation and inhibits tumorigenesis. J Biol Chem 1995; 270: 8037-43.
-
(1995)
J Biol Chem
, vol.270
, pp. 8037-8043
-
-
McLeod, A.R.1
Szyf, M.2
-
114
-
-
0031025621
-
Inhibition of tumorigenesis by a cytosine-DNA, methyltransferase, antisense oligodeoxynucleotide
-
Ramchandani S, MacLeod AR, Pinard M, von Hofe E, Szyf M. Inhibition of tumorigenesis by a cytosine-DNA, methyltransferase, antisense oligodeoxynucleotide. Proc Natl Acad Sci USA 1997; 94: 684-9.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 684-689
-
-
Ramchandani, S.1
McLeod, A.R.2
Pinard, M.3
von Hofe, E.4
Szyf, M.5
-
115
-
-
0033582470
-
Modified oligonucleotides as bona fide antagonists of proteins interacting with DNA. Hairpin antagonists of the human DNA methyltransferase
-
Bigey P, Knox JD, Croteau S, Bhattacharya SK, Théberge J, Szyf M. Modified oligonucleotides as bona fide antagonists of proteins interacting with DNA. Hairpin antagonists of the human DNA methyltransferase. J Biol Chem 1999; 274: 4594-606.
-
(1999)
J Biol Chem
, vol.274
, pp. 4594-4606
-
-
Bigey, P.1
Knox, J.D.2
Croteau, S.3
Bhattacharya, S.K.4
Théberge, J.5
Szyf, M.6
-
116
-
-
0035089787
-
Sequenceselective DNA binding drugs mithramycin A and chromomycin A3 are potent inhibitors of neuronal apoptosis induced by oxidative stress and DNA damage in cortical neurons
-
Chatterjee S, Zaman K, Ryu H, Conforto A, Ratan RR. Sequenceselective DNA binding drugs mithramycin A and chromomycin A3 are potent inhibitors of neuronal apoptosis induced by oxidative stress and DNA damage in cortical neurons. Ann Neurol 2001; 49: 345-354.
-
(2001)
Ann Neurol
, vol.49
, pp. 345-354
-
-
Chatterjee, S.1
Zaman, K.2
Ryu, H.3
Conforto, A.4
Ratan, R.R.5
-
117
-
-
68749083300
-
The complex relationship between folate/homocysteine metabolism and risk of Down syndrome
-
Coppedè F. The complex relationship between folate/homocysteine metabolism and risk of Down syndrome. Mutat. Res 2009; 682: 54-70.
-
(2009)
Mutat. Res
, vol.682
, pp. 54-70
-
-
Coppedè, F.1
-
118
-
-
0037075257
-
Plasma homocysteine as a risk factor for dementia and Alzheimer's disease
-
Seshadri S, Beiser A, Selhub J, et al. Plasma homocysteine as a risk factor for dementia and Alzheimer's disease. N Engl J Med 2002; 346: 476-83.
-
(2002)
N Engl J Med
, vol.346
, pp. 476-483
-
-
Seshadri, S.1
Beiser, A.2
Selhub, J.3
-
119
-
-
0038387939
-
Homocysteine and Alzheimer's disease
-
Morris MS. Homocysteine and Alzheimer's disease. Lancet Neurol 2003; 2: 425-8.
-
(2003)
Lancet Neurol
, vol.2
, pp. 425-428
-
-
Morris, M.S.1
-
120
-
-
0036523032
-
Folic acid deficiency and homocysteine impair DNA repair in hippocampal neurons and sensitize them to amyloid toxicity in experimental models of Alzheimer's disease
-
Kruman II, Kumaravel TS, Lohani A, et al. Folic acid deficiency and homocysteine impair DNA repair in hippocampal neurons and sensitize them to amyloid toxicity in experimental models of Alzheimer's disease. J Neurosci 2002; 22: 1752-62.
-
(2002)
J Neurosci
, vol.22
, pp. 1752-1762
-
-
Kruman, I.I.1
Kumaravel, T.S.2
Lohani, A.3
-
121
-
-
0037121817
-
Folate quenches oxidative damage in brains of apolipoprotein E-deficient mice: Augmentation by vitamin E
-
Shea TB, Rogers E. Folate quenches oxidative damage in brains of apolipoprotein E-deficient mice: augmentation by vitamin E. Brain Res Mol Brain Res 2002; 108: 1-6.
-
(2002)
Brain Res Mol Brain Res
, vol.108
, pp. 1-6
-
-
Shea, T.B.1
Rogers, E.2
-
122
-
-
0036019532
-
A1298C methylenetetrahydrofolate reductase mutation and coronary artery disease: Relationships with C677T polymorphism and homocysteine/folate metabolism
-
Friso S, Girelli D, Trabetti E, et al. A1298C methylenetetrahydrofolate reductase mutation and coronary artery disease: relationships with C677T polymorphism and homocysteine/folate metabolism. Clin Exp Med 2002; 2: 7-12.
-
(2002)
Clin Exp Med
, vol.2
, pp. 7-12
-
-
Friso, S.1
Girelli, D.2
Trabetti, E.3
-
123
-
-
33846324781
-
Sadenosyl methionine: A connection between nutritional and genetic risk factors for neurodegeneration in Alzheimer's disease
-
Tchantchou F, Graves M, Ortiz D, Chan A, Rogers E, Shea TB. Sadenosyl methionine: a connection between nutritional and genetic risk factors for neurodegeneration in Alzheimer's disease. J Nutr Health Aging 2006; 10: 541-4.
-
(2006)
J Nutr Health Aging
, vol.10
, pp. 541-544
-
-
Tchantchou, F.1
Graves, M.2
Ortiz, D.3
Chan, A.4
Rogers, E.5
Shea, T.B.6
-
124
-
-
20244361897
-
A pilot study of vitamins to lower plasma homocysteine levels in Alzheimer disease
-
Aisen PS, Egelko S, Andrews H, et al. A pilot study of vitamins to lower plasma homocysteine levels in Alzheimer disease. Am J Geriatr Psychiatry 2003; 11: 246-9.
-
(2003)
Am J Geriatr Psychiatry
, vol.11
, pp. 246-249
-
-
Aisen, P.S.1
Egelko, S.2
Andrews, H.3
-
125
-
-
54049106963
-
High-dose B vitamin supplementation and cognitive decline in Alzheimer disease: A randomized controlled trial
-
Aisen PS, Schneider LS, Sano M, et al. High-dose B vitamin supplementation and cognitive decline in Alzheimer disease: a randomized controlled trial. JAMA 2008; 300: 1774-83.
-
(2008)
JAMA
, vol.300
, pp. 1774-1783
-
-
Aisen, P.S.1
Schneider, L.S.2
Sano, M.3
-
126
-
-
58149191631
-
Efficacy of a vitamin/nutriceutical formulation for early-stage Alzheimer's disease: A 1-year, open-label pilot study with an 16-month caregiver extension
-
Chan A, Paskavitz J, Remington R, Rasmussen S, Shea TB. Efficacy of a vitamin/nutriceutical formulation for early-stage Alzheimer's disease: a 1-year, open-label pilot study with an 16-month caregiver extension. Am J Alzheimers Dis Other Demen 2008; 23: 571-85.
-
(2008)
Am J Alzheimers Dis Other Demen
, vol.23
, pp. 571-585
-
-
Chan, A.1
Paskavitz, J.2
Remington, R.3
Rasmussen, S.4
Shea, T.B.5
-
127
-
-
0025219026
-
Genomic organization of the human amyloid beta-protein precursor gene
-
Yoshikai S, Sasaki H, Doh-ura K, Furuya H, Sakaki Y. Genomic organization of the human amyloid beta-protein precursor gene. Gene 1990; 87: 257-63.
-
(1990)
Gene
, vol.87
, pp. 257-263
-
-
Yoshikai, S.1
Sasaki, H.2
Doh-ura, K.3
Furuya, H.4
Sakaki, Y.5
-
128
-
-
0028169984
-
The upstream promoter of the beta-amyloid precursor protein gene (APP) shows differential patterns of methylation in human brain
-
Rogaev EI, Lukiw WJ, Lavrushina O, Rogaeva EA, St George-Hyslop PH. The upstream promoter of the beta-amyloid precursor protein gene (APP) shows differential patterns of methylation in human brain. Genomics 1994; 22: 340-7.
-
(1994)
Genomics
, vol.22
, pp. 340-347
-
-
Rogaev, E.I.1
Lukiw, W.J.2
Lavrushina, O.3
Rogaeva, E.A.4
St. George-Hyslop, P.H.5
-
129
-
-
0029440466
-
Hypomethylation of the amyloid precursor protein gene in the brain of an Alzheimer's disease patient
-
West RL, Lee JM, Maroun LE. Hypomethylation of the amyloid precursor protein gene in the brain of an Alzheimer's disease patient. J Mol Neurosci 1995; 6: 141-6.
-
(1995)
J Mol Neurosci
, vol.6
, pp. 141-146
-
-
West, R.L.1
Lee, J.M.2
Maroun, L.E.3
-
130
-
-
0033052929
-
Reduction with age in methylcytosine in the promoter region-224 approximately-101 of the amyloid precursor protein gene in autopsy human cortex
-
Tohgi H, Utsugisawa K, Nagane Y, Yoshimura M, Genda Y, Ukitsu M. Reduction with age in methylcytosine in the promoter region-224 approximately-101 of the amyloid precursor protein gene in autopsy human cortex. Brain Res Mol Brain Res 1999; 70: 288-92.
-
(1999)
Brain Res Mol Brain Res
, vol.70
, pp. 288-292
-
-
Tohgi, H.1
Utsugisawa, K.2
Nagane, Y.3
Yoshimura, M.4
Genda, Y.5
Ukitsu, M.6
-
132
-
-
0027458127
-
Are somatic cells inherently deficient in methylation metabolism? A proposed mechanism for DNA methylation loss, senescence and aging
-
Cooney CA. Are somatic cells inherently deficient in methylation metabolism? A proposed mechanism for DNA methylation loss, senescence and aging. Growth Dev Aging 1993; 57: 261-73.
-
(1993)
Growth Dev Aging
, vol.57
, pp. 261-273
-
-
Cooney, C.A.1
-
133
-
-
3542991430
-
Differential chromosome sensitivity to 5-azacytidine in Alzheimer's disease
-
Payao SL, Smith MD, Bertolucci PH. Differential chromosome sensitivity to 5-azacytidine in Alzheimer's disease. Gerontology 1998; 44: 267-71.
-
(1998)
Gerontology
, vol.44
, pp. 267-271
-
-
Payao, S.L.1
Smith, M.D.2
Bertolucci, P.H.3
-
134
-
-
29644441522
-
Role of 14-3-3gamma in FE65-dependent gene transactivation mediated by the amyloid beta-protein precursor cytoplasmic fragment
-
Sumioka A, Nagaishi S, Yoshida T, Lin A, Miura M, Suzuki T. Role of 14-3-3gamma in FE65-dependent gene transactivation mediated by the amyloid beta-protein precursor cytoplasmic fragment. J Biol Chem 2005; 280: 42364-74.
-
(2005)
J Biol Chem
, vol.280
, pp. 42364-42374
-
-
Sumioka, A.1
Nagaishi, S.2
Yoshida, T.3
Lin, A.4
Miura, M.5
Suzuki, T.6
-
135
-
-
0035816661
-
A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60
-
Cao X, Sudhof TC. A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60. Science 2001; 293: 115-20.
-
(2001)
Science
, vol.293
, pp. 115-120
-
-
Cao, X.1
Sudhof, T.C.2
-
136
-
-
5444275067
-
The APP intracellular domain forms nuclear multiprotein complexes and regulates the transcription of its own precursor
-
von Rotz RC, Kohli BM, Bosset J, et al. The APP intracellular domain forms nuclear multiprotein complexes and regulates the transcription of its own precursor. J Cell Sci 2004; 117: 4435-48.
-
(2004)
J Cell Sci
, vol.117
, pp. 4435-4448
-
-
von Rotz, R.C.1
Kohli, B.M.2
Bosset, J.3
-
137
-
-
21444436589
-
Transcription regulation by the adaptor protein Fe65 and the nucleosome assembly factor SET
-
Telese F, Bruni P, Donizetti A, et al. Transcription regulation by the adaptor protein Fe65 and the nucleosome assembly factor SET. EMBO Rep 2005; 6: 77-82.
-
(2005)
EMBO Rep
, vol.6
, pp. 77-82
-
-
Telese, F.1
Bruni, P.2
Donizetti, A.3
-
138
-
-
45749151774
-
A putative role of the amyloid precursor protein intracellular domain (AICD) in transcription
-
Slomnicki LP, Lesniak W. A putative role of the amyloid precursor protein intracellular domain (AICD) in transcription. Acta Neurobiol Exp (Wars) 2008; 68: 219-28.
-
(2008)
Acta Neurobiol Exp (Wars)
, vol.68
, pp. 219-228
-
-
Slomnicki, L.P.1
Lesniak, W.2
-
139
-
-
40549088942
-
The FE65 proteins and Alzheimer's disease
-
McLoughlin DM, Miller CC. The FE65 proteins and Alzheimer's disease. J Neurosci Res 2008; 86: 744-54.
-
(2008)
J Neurosci Res
, vol.86
, pp. 744-754
-
-
McLoughlin, D.M.1
Miller, C.C.2
-
140
-
-
36349036676
-
Fe65 stimulates proteolytic liberation of the beta-amyloid precursor protein intracellular domain
-
Wiley JC, Smith EA, Hudson MP, Ladiges WC, Bothwell M. Fe65 stimulates proteolytic liberation of the beta-amyloid precursor protein intracellular domain. J Biol Chem 2007; 282: 33313-25.
-
(2007)
J Biol Chem
, vol.282
, pp. 33313-33325
-
-
Wiley, J.C.1
Smith, E.A.2
Hudson, M.P.3
Ladiges, W.C.4
Bothwell, M.5
-
141
-
-
9144234107
-
Inhibition of histone deacetylation enhances the neurotoxicity induced by the C-terminal fragments of amyloid precursor protein
-
Kim HS, Kim EM, Kim NJ, et al. Inhibition of histone deacetylation enhances the neurotoxicity induced by the C-terminal fragments of amyloid precursor protein. J Neurosci Res 2004; 75: 117-24.
-
(2004)
J Neurosci Res
, vol.75
, pp. 117-124
-
-
Kim, H.S.1
Kim, E.M.2
Kim, N.J.3
-
142
-
-
0034682736
-
Involvement of the TIP60 histone acetylase complex in DNA repair and apoptosis
-
Ikura T, Ogryzko VV, Grigoriev M, et al. Involvement of the TIP60 histone acetylase complex in DNA repair and apoptosis. Cell 2000; 102: 463-73.
-
(2000)
Cell
, vol.102
, pp. 463-473
-
-
Ikura, T.1
Ogryzko, V.V.2
Grigoriev, M.3
-
144
-
-
0031665061
-
Prevalence of Alzheimer's disease and other dementias in rural India: The Indo-US study
-
Chandra V, Ganguli M, Pandav R, Johnston J, Belle S, DeKosky ST. Prevalence of Alzheimer's disease and other dementias in rural India: the Indo-US study. Neurology 1998; 51: 1000-8.
-
(1998)
Neurology
, vol.51
, pp. 1000-1008
-
-
Chandra, V.1
Ganguli, M.2
Pandav, R.3
Johnston, J.4
Belle, S.5
DeKosky, S.T.6
-
145
-
-
0035949786
-
Incidence of Alzheimer's disease in a rural community in India: The Indo-US study
-
Chandra V, Pandav R, Dodge HH et al. Incidence of Alzheimer's disease in a rural community in India: the Indo-US study. Neurology 2001; 57: 985-9.
-
(2001)
Neurology
, vol.57
, pp. 985-989
-
-
Chandra, V.1
Pandav, R.2
Dodge, H.H.3
-
146
-
-
0035503597
-
The curry spice curcumin reduces oxidative damage and amyloid pathology in an Alzheimer transgenic mouse
-
Lim GP, Chu T, Yang F, Beech W, Frautschy SA, Cole GM. The curry spice curcumin reduces oxidative damage and amyloid pathology in an Alzheimer transgenic mouse. J Neurosci 2001; 21: 8370-7.
-
(2001)
J Neurosci
, vol.21
, pp. 8370-8377
-
-
Lim, G.P.1
Chu, T.2
Yang, F.3
Beech, W.4
Frautschy, S.A.5
Cole, G.M.6
-
147
-
-
1542364225
-
Curcumin has potent anti-amyloidogenic effects for Alzheimer's Î2-amyloid fibrils in vitro
-
Ono K, Hasegawa K, Naiki H, Yamada M. Curcumin has potent anti-amyloidogenic effects for Alzheimer's Î2-amyloid fibrils in vitro. J Neurosci Res 2004; 75: 742-50.
-
(2004)
J Neurosci Res
, vol.75
, pp. 742-750
-
-
Ono, K.1
Hasegawa, K.2
Naiki, H.3
Yamada, M.4
-
148
-
-
20044370990
-
Curcumin inhibits formation of amyloid beta oligomers and fibrils, binds plaques, and reduces amyloid in vivo
-
Yang F, Lim GP, Begum AN, et al. Curcumin inhibits formation of amyloid beta oligomers and fibrils, binds plaques, and reduces amyloid in vivo. J Biol Chem 2005; 280: 5892-901.
-
(2005)
J Biol Chem
, vol.280
, pp. 5892-5901
-
-
Yang, F.1
Lim, G.P.2
Begum, A.N.3
-
149
-
-
67650705731
-
Amelioration of cognitive deficits and neurodegeneration by curcumin in rat model of sporadic dementia of Alzheimer's type (SDAT)
-
Ishrat T, Hoda MN, Khan MB, et al. Amelioration of cognitive deficits and neurodegeneration by curcumin in rat model of sporadic dementia of Alzheimer's type (SDAT). Eur Neuropsychopharmacol 2009; 19: 636-47.
-
(2009)
Eur Neuropsychopharmacol
, vol.19
, pp. 636-647
-
-
Ishrat, T.1
Hoda, M.N.2
Khan, M.B.3
-
150
-
-
65249115921
-
Fe65 is required for Tip60-directed histone H4 acetylation at DNA strand breaks
-
Stante M, Minopoli G, Passaro F, Raia M, Vecchio LD, Russo T. Fe65 is required for Tip60-directed histone H4 acetylation at DNA strand breaks. Proc Natl Acad Sci USA 2009; 106: 5093-8.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 5093-5098
-
-
Stante, M.1
Minopoli, G.2
Passaro, F.3
Raia, M.4
Vecchio, L.D.5
Russo, T.6
-
151
-
-
58149267462
-
Nicotinamide restores cognition in Alzheimer's disease transgenic mice via a mechanism involving sirtuin inhibition and selective reduction of Thr231-phosphotau
-
Green KN, Steffan JS, Martinez-Coria H, et al. Nicotinamide restores cognition in Alzheimer's disease transgenic mice via a mechanism involving sirtuin inhibition and selective reduction of Thr231-phosphotau. J Neurosci 2008; 28: 11500-10.
-
(2008)
J Neurosci
, vol.28
, pp. 11500-11510
-
-
Green, K.N.1
Steffan, J.S.2
Martinez-Coria, H.3
-
152
-
-
67349220155
-
Phenylbutyrate ameliorates cognitive deficit and reduces tau pathology in an Alzheimer's disease mouse model
-
Ricobaraza A, Cuadrado-Tejedor M, Pérez-Mediavilla A, Frechilla D, Del Río J, García-Osta A. Phenylbutyrate ameliorates cognitive deficit and reduces tau pathology in an Alzheimer's disease mouse model. Neuropsychopharmacology 2009; 34: 1721-32.
-
(2009)
Neuropsychopharmacology
, vol.34
, pp. 1721-1732
-
-
Ricobaraza, A.1
Cuadrado-Tejedor, M.2
Pérez-Mediavilla, A.3
Frechilla, D.4
Del Río, J.5
García-Osta, A.6
-
153
-
-
80051984937
-
Sodium butyrate improves memory function in an Alzheimer's disease mouse model when administered at an advanced stage of disease progression
-
Govindarajan N, Agis-Balboa RC, Walter J, Sananbenesi F, Fischer A. Sodium butyrate improves memory function in an Alzheimer's disease mouse model when administered at an advanced stage of disease progression. J Alzheimers Dis 2011; 26: 187-97.
-
(2011)
J Alzheimers Dis
, vol.26
, pp. 187-197
-
-
Govindarajan, N.1
Agis-Balboa, R.C.2
Walter, J.3
Sananbenesi, F.4
Fischer, A.5
-
154
-
-
67649310030
-
Dysregulation of histone acetylation in the APP/PS1 mouse model of Alzheimer's disease
-
Francis YI, Fà M, Ashraf H, et al. Dysregulation of histone acetylation in the APP/PS1 mouse model of Alzheimer's disease. J Alzheimers Dis 2009; 18: 131-9.
-
(2009)
J Alzheimers Dis
, vol.18
, pp. 131-139
-
-
Francis, Y.I.1
Fà, M.2
Ashraf, H.3
-
155
-
-
34248523169
-
Recovery of learning and memory is associated with chromatin remodelling
-
Fischer A, Sananbenesi F, Wang X, Dobbin M, Tsai LH. Recovery of learning and memory is associated with chromatin remodelling. Nature 2007; 447: 178-82.
-
(2007)
Nature
, vol.447
, pp. 178-182
-
-
Fischer, A.1
Sananbenesi, F.2
Wang, X.3
Dobbin, M.4
Tsai, L.H.5
-
156
-
-
34248549732
-
Behavioural neuroscience: Down memory lane
-
Sweatt JD. Behavioural neuroscience: Down memory lane. Nature 2007; 447: 151-2.
-
(2007)
Nature
, vol.447
, pp. 151-152
-
-
Sweatt, J.D.1
-
157
-
-
65549123471
-
HDAC2 negatively regulates memory formation and synaptic plasticity
-
Guan JS, Haggarty SJ, Giacometti E, et al. HDAC2 negatively regulates memory formation and synaptic plasticity. Nature 2009; 459: 55-60.
-
(2009)
Nature
, vol.459
, pp. 55-60
-
-
Guan, J.S.1
Haggarty, S.J.2
Giacometti, E.3
-
158
-
-
75649094081
-
Pharmacology of epigenetics in brain disorders
-
Narayan P, Dragunow M. Pharmacology of epigenetics in brain disorders. Br J Pharmacol 2010; 159: 285-303.
-
(2010)
Br J Pharmacol
, vol.159
, pp. 285-303
-
-
Narayan, P.1
Dragunow, M.2
-
160
-
-
0029145509
-
Valproate in the treatment of behavioral agitation in elderly patients with dementia
-
Lott AD, McElroy SL, Keys MA. Valproate in the treatment of behavioral agitation in elderly patients with dementia. J Neuropsychiatry Clin Neurosci 1995; 7: 314-9.
-
(1995)
J Neuropsychiatry Clin Neurosci
, vol.7
, pp. 314-319
-
-
Lott, A.D.1
McElroy, S.L.2
Keys, M.A.3
-
161
-
-
0031445786
-
A pilot study on the use of divalproex sodium in the treatment of behavioral agitation in elderly patients with dementia: Assessment with the BEHAVE-AD and CGI rating scales
-
Kasckow JW, McElroy SL, Cameron RL, Mahler LL, Fudala SJ. A pilot study on the use of divalproex sodium in the treatment of behavioral agitation in elderly patients with dementia: assessment with the BEHAVE-AD and CGI rating scales. Curr Ther Res Clin Exp 1997; 58: 981-9.
-
(1997)
Curr Ther Res Clin Exp
, vol.58
, pp. 981-989
-
-
Kasckow, J.W.1
McElroy, S.L.2
Cameron, R.L.3
Mahler, L.L.4
Fudala, S.J.5
-
162
-
-
0030853759
-
Treatment of dementia with behavioral disturbance using divalproex or a combination of divalproex and a neuroleptic
-
Narayan M, Nelson JC. Treatment of dementia with behavioral disturbance using divalproex or a combination of divalproex and a neuroleptic. J Clin Psychiatry 1997; 58: 351-4.
-
(1997)
J Clin Psychiatry
, vol.58
, pp. 351-354
-
-
Narayan, M.1
Nelson, J.C.2
-
163
-
-
0030779517
-
An open trial of valproate for agitation in geriatric neuropsychiatric disorders
-
Porsteinsson AP, Tariot PN, Erb R, Gaile S. An open trial of valproate for agitation in geriatric neuropsychiatric disorders. Am J Geriatr Psychiatry 1997; 5: 344-51.
-
(1997)
Am J Geriatr Psychiatry
, vol.5
, pp. 344-351
-
-
Porsteinsson, A.P.1
Tariot, P.N.2
Erb, R.3
Gaile, S.4
-
164
-
-
0035172216
-
Placebo-controlled study of divalproex sodium for agitation in dementia
-
Porsteinsson AP, Tariot PN, Erb R, et al. Placebo-controlled study of divalproex sodium for agitation in dementia. Am J Geriatr Psychiatry 2001; 9: 58-66.
-
(2001)
Am J Geriatr Psychiatry
, vol.9
, pp. 58-66
-
-
Porsteinsson, A.P.1
Tariot, P.N.2
Erb, R.3
-
165
-
-
0038679746
-
Valproate therapy for agitation in dementia: Openlabel extension of a doubleblind trial
-
Porsteinsson AP, Tariot PN, Jakimovich LJ, et al. Valproate therapy for agitation in dementia: openlabel extension of a doubleblind trial. Am J Geriatr Psychiatry 2003; 11: 434-40.
-
(2003)
Am J Geriatr Psychiatry
, vol.11
, pp. 434-440
-
-
Porsteinsson, A.P.1
Tariot, P.N.2
Jakimovich, L.J.3
-
166
-
-
0031916507
-
Valproic acid treatment of agitation in dementia
-
Herrmann N. Valproic acid treatment of agitation in dementia. Can J Psychiatry 1998; 43: 69-72.
-
(1998)
Can J Psychiatry
, vol.43
, pp. 69-72
-
-
Herrmann, N.1
-
167
-
-
0031974036
-
The efficacy and tolerability of divalproex sodium in elderly demented patients with behavioral disturbances
-
Kunik ME, Puryear L, Orengo CA, Molinari V, Workman RH Jr. The efficacy and tolerability of divalproex sodium in elderly demented patients with behavioral disturbances. Int J Geriatr Psychiatry 1998; 13: 29-34.
-
(1998)
Int J Geriatr Psychiatry
, vol.13
, pp. 29-34
-
-
Kunik, M.E.1
Puryear, L.2
Orengo, C.A.3
Molinari, V.4
Workman Jr., R.H.5
-
168
-
-
0035010076
-
Safety and tolerability of divalproex sodium in the treatment of signs and symptoms of mania in elderly patients with dementia: Results of a double-blind, placebo-controlled trial
-
Tariot PN, Schneider LS, Mintzer JE, et al. Safety and tolerability of divalproex sodium in the treatment of signs and symptoms of mania in elderly patients with dementia: results of a double-blind, placebo-controlled trial. Curr Ther Res Clin Exp 2001; 62: 51-67.
-
(2001)
Curr Ther Res Clin Exp
, vol.62
, pp. 51-67
-
-
Tariot, P.N.1
Schneider, L.S.2
Mintzer, J.E.3
-
169
-
-
33644877231
-
Divalproex sodium in nursing home residents with possible or probable Alzheimer disease complicated by agitation: A randomized, controlled trial
-
Tariot PN, Raman R, Jakimovich L, et al. Divalproex sodium in nursing home residents with possible or probable Alzheimer disease complicated by agitation: a randomized, controlled trial. Am J Geriatr Psychiatry 2005; 13: 942-9.
-
(2005)
Am J Geriatr Psychiatry
, vol.13
, pp. 942-949
-
-
Tariot, P.N.1
Raman, R.2
Jakimovich, L.3
-
170
-
-
0036085791
-
Sodium valproate in the treatment of aggressive behavior in patients with dementia-a randomized placebo controlled clinical trial
-
Sival RC, Haffmans PM, Jansen PA, Duursma SA, Eikelenboom P. Sodium valproate in the treatment of aggressive behavior in patients with dementia-a randomized placebo controlled clinical trial. Int J Geriatr Psychiatry 2002; 17: 579-85.
-
(2002)
Int J Geriatr Psychiatry
, vol.17
, pp. 579-585
-
-
Sival, R.C.1
Haffmans, P.M.2
Jansen, P.A.3
Duursma, S.A.4
Eikelenboom, P.5
-
171
-
-
35948976890
-
Report on an open-label prospective study of divalproex sodium for the behavioral and psychological symptoms of dementia as monotherapy and in combination with second generation antipsychotic medication
-
Forester B, Vanelli M, Hyde J, et al. Report on an open-label prospective study of divalproex sodium for the behavioral and psychological symptoms of dementia as monotherapy and in combination with second generation antipsychotic medication. Am J Geriatr Pharmacother 2007; 5: 209-17.
-
(2007)
Am J Geriatr Pharmacother
, vol.5
, pp. 209-217
-
-
Forester, B.1
Vanelli, M.2
Hyde, J.3
-
172
-
-
0032716797
-
The methylation status of cytosines in a tau gene promoter region alters with age to downregulate transcriptional activity in human cerebral cortex
-
Tohgi H, Utsugisawa K, Nagane Y, Yoshimura M, Ukitsu M, Genda Y. The methylation status of cytosines in a tau gene promoter region alters with age to downregulate transcriptional activity in human cerebral cortex. Neurosci Lett 1999; 275: 89-92.
-
(1999)
Neurosci Lett
, vol.275
, pp. 89-92
-
-
Tohgi, H.1
Utsugisawa, K.2
Nagane, Y.3
Yoshimura, M.4
Ukitsu, M.5
Genda, Y.6
-
174
-
-
78650179659
-
Epigenetic changes in Alzheimer's disease: Decrements in DNA methylation
-
Mastroeni D, Grover A, Delvaux E, Whiteside C, Coleman PD, Rogers J. Epigenetic changes in Alzheimer's disease: Decrements in DNA methylation. Neurobiol Aging 2010; 31: 2025-37.
-
(2010)
Neurobiol Aging
, vol.31
, pp. 2025-2037
-
-
Mastroeni, D.1
Grover, A.2
Delvaux, E.3
Whiteside, C.4
Coleman, P.D.5
Rogers, J.6
-
175
-
-
49349110718
-
Tau hyperphosphorylation correlates with reduced methylation of protein phosphatase 2A
-
Zhou XW, Gustafsson JA, Tanila H, et al. Tau hyperphosphorylation correlates with reduced methylation of protein phosphatase 2A. Neurobiol Dis 2008; 31: 386.
-
(2008)
Neurobiol Dis
, vol.31
, pp. 386
-
-
Zhou, X.W.1
Gustafsson, J.A.2
Tanila, H.3
-
176
-
-
34848871269
-
Methotrexate decreases PP2A methylation and increases tau phosphorylation in neuron
-
Yoon SY, Choi HI, Choi JE, Sul CA, Choi JM, Kim DH. Methotrexate decreases PP2A methylation and increases tau phosphorylation in neuron. Biochem Biophys Res Commun 2007; 363: 811-6.
-
(2007)
Biochem Biophys Res Commun
, vol.363
, pp. 811-816
-
-
Yoon, S.Y.1
Choi, H.I.2
Choi, J.E.3
Sul, C.A.4
Choi, J.M.5
Kim, D.H.6
-
177
-
-
51649119364
-
Homocysteine induces tau phosphorylation by inactivating protein phosphatase 2A in rat hippocampus
-
Zhang CE, Tian Q, Wei W, et al. Homocysteine induces tau phosphorylation by inactivating protein phosphatase 2A in rat hippocampus. Neurobiol Aging 2008; 29: 1654-65.
-
(2008)
Neurobiol Aging
, vol.29
, pp. 1654-1665
-
-
Zhang, C.E.1
Tian, Q.2
Wei, W.3
-
178
-
-
33646876851
-
The cell cycle as a therapeutic target for Alzheimer's disease
-
Neve RL, Mcphie DL. The cell cycle as a therapeutic target for Alzheimer's disease. Pharmacol Ther 2006; 111: 99-113.
-
(2006)
Pharmacol Ther
, vol.111
, pp. 99-113
-
-
Neve, R.L.1
McPhie, D.L.2
-
179
-
-
58149174210
-
Methylation of P16, P21, P27, RB1 and P53 genes in odontogenic keratocysts
-
Moreira PR, Guimarães MM, Guimarães AL, et al. Methylation of P16, P21, P27, RB1 and P53 genes in odontogenic keratocysts. J Oral Pathol Med 2009; 38: 99-103.
-
(2009)
J Oral Pathol Med
, vol.38
, pp. 99-103
-
-
Moreira, P.R.1
Guimarães, M.M.2
Guimarães, A.L.3
-
180
-
-
34848895533
-
Cell cycle-dependent transcription of cyclin B2 is influenced by DNA methylation but is independent of methylation in the CDE and CHR elements
-
Tschöp K, Engeland K. Cell cycle-dependent transcription of cyclin B2 is influenced by DNA methylation but is independent of methylation in the CDE and CHR elements. FEBS J 2007; 274: 5235-49.
-
(2007)
FEBS J
, vol.274
, pp. 5235-5249
-
-
Tschöp, K.1
Engeland, K.2
-
181
-
-
0031771497
-
The human ARF cell cycle regulatory gene promoter is a CpG island which can be silenced by DNA methylation and down-regulated by wild-type p53
-
Robertson KD, Jones PA. The human ARF cell cycle regulatory gene promoter is a CpG island which can be silenced by DNA methylation and down-regulated by wild-type p53. Mol Cell Biol 1998; 18: 6457-73.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 6457-6473
-
-
Robertson, K.D.1
Jones, P.A.2
-
182
-
-
21444459770
-
Loss of caspase-1 gene expression in human gastric carcinomas and cell lines
-
Jee CD, Lee HS, Bae SI, et al. Loss of caspase-1 gene expression in human gastric carcinomas and cell lines. Int J Oncol 2005; 26: 1265-71.
-
(2005)
Int J Oncol
, vol.26
, pp. 1265-1271
-
-
Jee, C.D.1
Lee, H.S.2
Bae, S.I.3
-
183
-
-
51949094991
-
Role of myofibroblasts in innate chemoresistance of pancreatic carcinoma--epigenetic downregulation of caspases
-
Müerköster SS, Werbing V, Koch D, et al. Role of myofibroblasts in innate chemoresistance of pancreatic carcinoma--epigenetic downregulation of caspases. Int J Cancer 2008; 123: 1751-60.
-
(2008)
Int J Cancer
, vol.123
, pp. 1751-1760
-
-
Müerköster, S.S.1
Werbing, V.2
Koch, D.3
-
184
-
-
34249672387
-
Variations in DNA methylation patterns during the cell cycle of HeLa cells
-
Brown SE, Fraga MF, Weaver IC, Berdasco M, Szyf M. Variations in DNA methylation patterns during the cell cycle of HeLa cells. Epigenetics 2007; 2: 54-65.
-
(2007)
Epigenetics
, vol.2
, pp. 54-65
-
-
Brown, S.E.1
Fraga, M.F.2
Weaver, I.C.3
Berdasco, M.4
Szyf, M.5
-
185
-
-
0036892748
-
Multiple aspects of homocysteine neurotoxicity: Glutamate excitotoxicity, kinase hyperactivation and DNA damage
-
Ho PI, Ortiz D, Rogers E, Shea TB. Multiple aspects of homocysteine neurotoxicity: glutamate excitotoxicity, kinase hyperactivation and DNA damage. J Neurosci Res 2002; 70: 694-702.
-
(2002)
J Neurosci Res
, vol.70
, pp. 694-702
-
-
Ho, P.I.1
Ortiz, D.2
Rogers, E.3
Shea, T.B.4
-
186
-
-
33749685522
-
Vitamin B12, folic acid, and the nervous system
-
Reynolds E. Vitamin B12, folic acid, and the nervous system. Lancet Neurol 2006; 5: 949-60.
-
(2006)
Lancet Neurol
, vol.5
, pp. 949-960
-
-
Reynolds, E.1
-
187
-
-
0037047434
-
The gamma secretase-generated carboxyl-terminal domain of the amyloid precursor protein induces apoptosis via Tip60 in H4 cells
-
Kinoshita A, Whelan CM, Berezovska O, Hyman BT. The gamma secretase-generated carboxyl-terminal domain of the amyloid precursor protein induces apoptosis via Tip60 in H4 cells. J Biol Chem 2002; 277: 28530-6.
-
(2002)
J Biol Chem
, vol.277
, pp. 28530-28536
-
-
Kinoshita, A.1
Whelan, C.M.2
Berezovska, O.3
Hyman, B.T.4
-
188
-
-
49449115492
-
Epigenetic regulation of gene expression in the inflammatory response and relevance to common diseases
-
Wilson AG. Epigenetic regulation of gene expression in the inflammatory response and relevance to common diseases. J Periodontol 2008; 79: 1514-9.
-
(2008)
J Periodontol
, vol.79
, pp. 1514-1519
-
-
Wilson, A.G.1
-
189
-
-
49449106856
-
Methylation status of a single CpG site in the IL6 promoter is related to IL6 messenger RNA levels and rheumatoid arthritis
-
Nile CJ, Read RC, Akil M, Duff GW, Wilson AG. Methylation status of a single CpG site in the IL6 promoter is related to IL6 messenger RNA levels and rheumatoid arthritis. Arthritis Rheum 2008; 58: 2686-93.
-
(2008)
Arthritis Rheum
, vol.58
, pp. 2686-2693
-
-
Nile, C.J.1
Read, R.C.2
Akil, M.3
Duff, G.W.4
Wilson, A.G.5
-
190
-
-
34247118445
-
Epigenetic regulation of clusterin/apolipoprotein J expression in retinal pigment epithelial cells
-
Suuronen T, Nuutinen T, Ryhänen T, Kaarniranta K, Salminen A. Epigenetic regulation of clusterin/apolipoprotein J expression in retinal pigment epithelial cells. Biochem Biophys Res Commun 2007; 357: 397-401.
-
(2007)
Biochem Biophys Res Commun
, vol.357
, pp. 397-401
-
-
Suuronen, T.1
Nuutinen, T.2
Ryhänen, T.3
Kaarniranta, K.4
Salminen, A.5
-
191
-
-
0036718272
-
Beta-secretase protein and activity are increased in the neocortex in Alzheimer disease
-
Fukumoto H, Cheung BS, Hyman BT, Irizarry MC. Beta-secretase protein and activity are increased in the neocortex in Alzheimer disease. Arch Neurol 2002; 59: 1381-9.
-
(2002)
Arch Neurol
, vol.59
, pp. 1381-1389
-
-
Fukumoto, H.1
Cheung, B.S.2
Hyman, B.T.3
Irizarry, M.C.4
-
192
-
-
0036260892
-
Increased expression of the amyloid precursor beta-secretase in Alzheimer's disease
-
Holsinger RM, McLean CA, Beyreuther K, Masters CL, Evin G. Increased expression of the amyloid precursor beta-secretase in Alzheimer's disease. Ann Neurol 2002; 51: 783-6.
-
(2002)
Ann Neurol
, vol.51
, pp. 783-786
-
-
Holsinger, R.M.1
McLean, C.A.2
Beyreuther, K.3
Masters, C.L.4
Evin, G.5
-
193
-
-
0037236622
-
Elevated beta-secretase expression and enzymatic activity detected in sporadic Alzheimer disease
-
Yang LB, Lindholm K, Yan R, et al. Elevated beta-secretase expression and enzymatic activity detected in sporadic Alzheimer disease. Nat Med 2003; 9: 3-4.
-
(2003)
Nat Med
, vol.9
, pp. 3-4
-
-
Yang, L.B.1
Lindholm, K.2
Yan, R.3
-
194
-
-
59049087888
-
MicroRNA-298 and microRNA-328 regulate expression of mouse beta-amyloid precursor protein-converting enzyme 1
-
Boissonneault V, Plante I, Rivest S, Provost P. MicroRNA-298 and microRNA-328 regulate expression of mouse beta-amyloid precursor protein-converting enzyme 1. J Biol Chem 2009; 284: 1971-81.
-
(2009)
J Biol Chem
, vol.284
, pp. 1971-1981
-
-
Boissonneault, V.1
Plante, I.2
Rivest, S.3
Provost, P.4
-
195
-
-
38749095507
-
The expression of microRNA miR-107 decreases early in Alzheimer's disease and may accelerate disease progression through regulation of beta-site amyloid precursor protein-cleaving enzyme 1
-
Wang WX, Rajeev BW, Stromberg AJ, et al. The expression of microRNA miR-107 decreases early in Alzheimer's disease and may accelerate disease progression through regulation of beta-site amyloid precursor protein-cleaving enzyme 1. J Neurosci 2008; 28: 1213-23.
-
(2008)
J Neurosci
, vol.28
, pp. 1213-1223
-
-
Wang, W.X.1
Rajeev, B.W.2
Stromberg, A.J.3
-
196
-
-
46749083733
-
Expression of a noncoding RNA is elevated in Alzheimer's disease and drives rapid feed-forward regulation of beta-secretase
-
Faghihi MA, Modarresi F, Khalil AM, et al. Expression of a noncoding RNA is elevated in Alzheimer's disease and drives rapid feed-forward regulation of beta-secretase. Nat Med 2008; 14: 723-30.
-
(2008)
Nat Med
, vol.14
, pp. 723-730
-
-
Faghihi, M.A.1
Modarresi, F.2
Khalil, A.M.3
-
198
-
-
61349110680
-
MicroRNA regulation of Alzheimer's amyloid precursor protein expression
-
Hebert SS, Horre K, Nicolai L, et al. MicroRNA regulation of Alzheimer's amyloid precursor protein expression. Neurobiol Dis 2009; 33: 422-8.
-
(2009)
Neurobiol Dis
, vol.33
, pp. 422-428
-
-
Hebert, S.S.1
Horre, K.2
Nicolai, L.3
-
199
-
-
44049108170
-
Loss of microRNA cluster miR-29a/b-1 in sporadic Alzheimer's disease correlates with increased BACE1/beta-secretase expression
-
Hebert SS, Horre K, Nicolai L, et al. Loss of microRNA cluster miR-29a/b-1 in sporadic Alzheimer's disease correlates with increased BACE1/beta-secretase expression. Proc Natl Acad Sci USA 2008; 105: 6415-20.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 6415-6420
-
-
Hebert, S.S.1
Horre, K.2
Nicolai, L.3
-
200
-
-
33847203593
-
Micro-RNA speciation in fetal, adult and Alzheimer's disease hippocampus
-
Lukiw WJ. Micro-RNA speciation in fetal, adult and Alzheimer's disease hippocampus. Neuroreport 2007; 18: 297-300.
-
(2007)
Neuroreport
, vol.18
, pp. 297-300
-
-
Lukiw, W.J.1
-
201
-
-
65749093295
-
Micro-RNA abundance and stability in human brain: Specific alterations in Alzheimer's disease temporal lobe neocortex
-
Sethi P, Lukiw WJ. Micro-RNA abundance and stability in human brain: specific alterations in Alzheimer's disease temporal lobe neocortex. Neurosci Lett 2009; 459: 100-4.
-
(2009)
Neurosci Lett
, vol.459
, pp. 100-104
-
-
Sethi, P.1
Lukiw, W.J.2
-
202
-
-
47849124269
-
Identification of miRNA changes in Alzheimer's disease brain and CSF yields putative biomarkers and insights into disease pathways
-
Cogswell JP, Ward J, Taylor IA, et al. Identification of miRNA changes in Alzheimer's disease brain and CSF yields putative biomarkers and insights into disease pathways. J Alzheimers Dis 2008; 14: 27-41.
-
(2008)
J Alzheimers Dis
, vol.14
, pp. 27-41
-
-
Cogswell, J.P.1
Ward, J.2
Taylor, I.A.3
-
204
-
-
70450217879
-
Human DNA methylomes at base resolution show widespread epigenomic differences
-
Lister R, Pelizzola M, Dowen RH, et al. Human DNA methylomes at base resolution show widespread epigenomic differences. Nature 2009; 462: 315-22.
-
(2009)
Nature
, vol.462
, pp. 315-322
-
-
Lister, R.1
Pelizzola, M.2
Dowen, R.H.3
-
205
-
-
77649267695
-
Dynamic changes in the human methylome during differentiation
-
Laurent L, Wong E, Li G, et al. Dynamic changes in the human methylome during differentiation. Genome Res 2010; 20: 320-31.
-
(2010)
Genome Res
, vol.20
, pp. 320-331
-
-
Laurent, L.1
Wong, E.2
Li, G.3
-
206
-
-
34047116826
-
Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome
-
Weber M, Hellmann I, Stadler MB, et al. Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome. Nat Genet 2007; 39: 457-66.
-
(2007)
Nat Genet
, vol.39
, pp. 457-466
-
-
Weber, M.1
Hellmann, I.2
Stadler, M.B.3
-
207
-
-
33947315736
-
Cancer epigenomics: DNA methylomes and histonemodification maps
-
Esteller M. Cancer epigenomics: DNA methylomes and histonemodification maps. Nat Rev Genet 2007; 8: 286-98.
-
(2007)
Nat Rev Genet
, vol.8
, pp. 286-298
-
-
Esteller, M.1
-
208
-
-
42649089780
-
The methylome: Approaches for global DNA methylation profiling
-
Beck S, Rakyan VK. The methylome: approaches for global DNA methylation profiling. Trends Genet 2008; 24: 231-7.
-
(2008)
Trends Genet
, vol.24
, pp. 231-237
-
-
Beck, S.1
Rakyan, V.K.2
-
209
-
-
0026052179
-
A genomic scanning method for higher organisms using restriction sites as landmarks
-
Hatada I, Hayashizaki Y, Hirotsune S, Komatsubara H, Mukai T. A genomic scanning method for higher organisms using restriction sites as landmarks. Proc Natl Acad Sci USA 1991; 88: 9523-27.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 9523-9527
-
-
Hatada, I.1
Hayashizaki, Y.2
Hirotsune, S.3
Komatsubara, H.4
Mukai, T.5
-
210
-
-
70449112966
-
Basic concepts of microarrays and potential applications in clinical microbiology
-
Miller MB, Tang YW. Basic concepts of microarrays and potential applications in clinical microbiology. Clin Microbiol Rev 2009; 22: 611-33.
-
(2009)
Clin Microbiol Rev
, vol.22
, pp. 611-633
-
-
Miller, M.B.1
Tang, Y.W.2
-
212
-
-
0014936031
-
Reaction of sodium bisulfite with uracil, cytosine, and their derivatives
-
Hayatsu H, Wataya Y, Kai K, Iida S. Reaction of sodium bisulfite with uracil, cytosine, and their derivatives. Biochemistry 1970; 9: 2858-65.
-
(1970)
Biochemistry
, vol.9
, pp. 2858-2865
-
-
Hayatsu, H.1
Wataya, Y.2
Kai, K.3
Iida, S.4
-
213
-
-
37749031255
-
Next-generation sequencing transforms today's biology
-
Schuster SC. Next-generation sequencing transforms today's biology. Nat Methods 2008; 5: 16-8.
-
(2008)
Nat Methods
, vol.5
, pp. 16-18
-
-
Schuster, S.C.1
-
216
-
-
77952085655
-
Profiling DNA methylomes from microarray to genome-scale sequencing
-
Huang YW, Huang TH, Wang LS. Profiling DNA methylomes from microarray to genome-scale sequencing. Technol Cancer Res Treat 2010; 9: 139-47.
-
(2010)
Technol Cancer Res Treat
, vol.9
, pp. 139-147
-
-
Huang, Y.W.1
Huang, T.H.2
Wang, L.S.3
-
217
-
-
70349312354
-
ChIP-seq: Advantages and challenges of a maturing technology
-
Park PJ. ChIP-seq: advantages and challenges of a maturing technology. Nat Rev Genet 2009; 10: 669-80.
-
(2009)
Nat Rev Genet
, vol.10
, pp. 669-680
-
-
Park, P.J.1
-
218
-
-
72849144434
-
Sequencing technologies-the next generation
-
Metzker ML. Sequencing technologies-the next generation Nat Rev Genet 2010; 11: 31-46.
-
(2010)
Nat Rev Genet
, vol.11
, pp. 31-46
-
-
Metzker, M.L.1
-
219
-
-
68949213578
-
Insights from genomic profiling of transcription factors
-
Farnham PJ. Insights from genomic profiling of transcription factors. Nat Rev Genet 2009; 10: 605-16.
-
(2009)
Nat Rev Genet
, vol.10
, pp. 605-616
-
-
Farnham, P.J.1
-
220
-
-
60349089645
-
Nucleosome positioning and gene regulation: Advances through genomics
-
Jiang C, Pugh BF. Nucleosome positioning and gene regulation: advances through genomics. Nat Rev Genet 2009; 10: 161-72.
-
(2009)
Nat Rev Genet
, vol.10
, pp. 161-172
-
-
Jiang, C.1
Pugh, B.F.2
-
221
-
-
37249012276
-
Nucleosome destabilization in the epigenetic regulation of gene expression
-
Henikoff S. Nucleosome destabilization in the epigenetic regulation of gene expression. Nat Rev Genet 2008; 9: 15-26.
-
(2008)
Nat Rev Genet
, vol.9
, pp. 15-26
-
-
Henikoff, S.1
-
222
-
-
33847070442
-
The role of chromatin during transcription
-
Li B, Carey M, Workman JL. The role of chromatin during transcription. Cell 2007; 128: 707-19.
-
(2007)
Cell
, vol.128
, pp. 707-719
-
-
Li, B.1
Carey, M.2
Workman, J.L.3
-
223
-
-
34249299791
-
The complex language of chromatin regulation during transcription
-
Berger SL. The complex language of chromatin regulation during transcription. Nature 2007; 447: 407-12.
-
(2007)
Nature
, vol.447
, pp. 407-412
-
-
Berger, S.L.1
-
225
-
-
0034704248
-
Genome-wide location and function of DNA binding proteins
-
Ren B, Robert F, Wyrick JJ, et al. Genome-wide location and function of DNA binding proteins. Science 2000; 290: 2306-9.
-
(2000)
Science
, vol.290
, pp. 2306-2309
-
-
Ren, B.1
Robert, F.2
Wyrick, J.J.3
-
226
-
-
34250159524
-
Genome-wide mapping of in vivo protein-DNA interactions
-
Johnson DS, Mortazavi A, Myers RM, Wold B. Genome-wide mapping of in vivo protein-DNA interactions. Science 2007; 316: 1497-502.
-
(2007)
Science
, vol.316
, pp. 1497-1502
-
-
Johnson, D.S.1
Mortazavi, A.2
Myers, R.M.3
Wold, B.4
-
227
-
-
34249026300
-
High-resolution profiling of histone methylations in the human genome
-
Barski A, Cuddapah S, Cui K, et al. High-resolution profiling of histone methylations in the human genome. Cell 2007; 129: 823-37.
-
(2007)
Cell
, vol.129
, pp. 823-837
-
-
Barski, A.1
Cuddapah, S.2
Cui, K.3
-
228
-
-
34547624303
-
Genome-wide maps of chromatin state in pluripotent and lineage-committed cells
-
Mikkelsen TS, Ku M, Jaffe DB, et al. Genome-wide maps of chromatin state in pluripotent and lineage-committed cells. Nature 2007; 448: 553-60.
-
(2007)
Nature
, vol.448
, pp. 553-560
-
-
Mikkelsen, T.S.1
Ku, M.2
Jaffe, D.B.3
-
229
-
-
46249112085
-
Combinatorial patterns of histone acetylations and methylations in the human genome
-
Wang Z, Zang C, Rosenfeld JA, et al. Combinatorial patterns of histone acetylations and methylations in the human genome. Nat Genet 2008; 40: 897-903.
-
(2008)
Nat Genet
, vol.40
, pp. 897-903
-
-
Wang, Z.1
Zang, C.2
Rosenfeld, J.A.3
-
230
-
-
2942518343
-
Mapping global histone acetylation patterns to gene expression
-
Kurdistani SK, Tavazoie S, Grunstein M. Mapping global histone acetylation patterns to gene expression. Cell 2004; 117: 721-33.
-
(2004)
Cell
, vol.117
, pp. 721-733
-
-
Kurdistani, S.K.1
Tavazoie, S.2
Grunstein, M.3
-
231
-
-
26444508841
-
Single-nucleosome mapping of histone modifications in S. cerevisiae
-
Liu CL, Kaplan T, Kim M, et al. Single-nucleosome mapping of histone modifications in S. cerevisiae. PLoS Biol 2005; 3: e328.
-
(2005)
PLoS Biol
, vol.3
-
-
Liu, C.L.1
Kaplan, T.2
Kim, M.3
-
232
-
-
39449088572
-
Genome-wide approaches to studying chromatin modifications
-
Schones DE, Zhao K. Genome-wide approaches to studying chromatin modifications. Nat Rev Genet 2008; 9: 179-91.
-
(2008)
Nat Rev Genet
, vol.9
, pp. 179-191
-
-
Schones, D.E.1
Zhao, K.2
-
233
-
-
38049179307
-
Core candidate neurochemical and imaging biomarkers of Alzheimer's disease
-
Hampel H, Burger K, Teipel SJ, Bokde AL, Zetterberg H, Blennow K. Core candidate neurochemical and imaging biomarkers of Alzheimer's disease. Alzheimers Dement 2008; 4: 38-48.
-
(2008)
Alzheimers Dement
, vol.4
, pp. 38-48
-
-
Hampel, H.1
Burger, K.2
Teipel, S.J.3
Bokde, A.L.4
Zetterberg, H.5
Blennow, K.6
-
234
-
-
70049108710
-
Computational anatomy with the SPM software
-
Ashburner J. Computational anatomy with the SPM software. Magn Reson Imaging 2009; 27: 1163-74.
-
(2009)
Magn Reson Imaging
, vol.27
, pp. 1163-1174
-
-
Ashburner, J.1
-
235
-
-
77955551854
-
The efficacy of a voxel-based morphometry on the analysis of imaging in schizophrenia, temporal lobe epilepsy, and Alzheimer's disease/mild cognitive impairment: A review
-
Kakeda S, Korogi Y. The efficacy of a voxel-based morphometry on the analysis of imaging in schizophrenia, temporal lobe epilepsy, and Alzheimer's disease/mild cognitive impairment: a review. Neuroradiology 2010; 52: 711-21.
-
(2010)
Neuroradiology
, vol.52
, pp. 711-721
-
-
Kakeda, S.1
Korogi, Y.2
-
237
-
-
34447636593
-
3D maps from multiple MRI illustrate changing atrophy patterns as subjects progress from mild cognitive impairment to Alzheimer's disease
-
Whitwell JL, Przybelski SA, Weigand SD, et al. 3D maps from multiple MRI illustrate changing atrophy patterns as subjects progress from mild cognitive impairment to Alzheimer's disease. Brain 2007; 130(Pt 7): 1777-86.
-
(2007)
Brain
, vol.130
, Issue.PART 7
, pp. 1777-1786
-
-
Whitwell, J.L.1
Przybelski, S.A.2
Weigand, S.D.3
-
238
-
-
45849094758
-
Longitudinal neuroanatomical changes determined by deformationbased morphometry in a mouse model of Alzheimer's disease
-
Lau JC, Lerch JP, Sled JG, Henkelman RM, Evans AC, Bedell BJ. Longitudinal neuroanatomical changes determined by deformationbased morphometry in a mouse model of Alzheimer's disease. Neuroimage 2008; 42: 19-27.
-
(2008)
Neuroimage
, vol.42
, pp. 19-27
-
-
Lau, J.C.1
Lerch, J.P.2
Sled, J.G.3
Henkelman, R.M.4
Evans, A.C.5
Bedell, B.J.6
-
239
-
-
23844442499
-
Longitudinal volumetric MRI change and rate of cognitive decline
-
Mungas D, Harvey D, Reed BR, et al. Longitudinal volumetric MRI change and rate of cognitive decline. Neurology 2005; 65: 565-71.
-
(2005)
Neurology
, vol.65
, pp. 565-571
-
-
Mungas, D.1
Harvey, D.2
Reed, B.R.3
-
240
-
-
84883845660
-
Tensor-based morphometry with mappings parameterized by stationary velocity fields in Alzheimer's disease neuroimaging initiative
-
Bossa MN, Zacur E, Olmos S. Tensor-based morphometry with mappings parameterized by stationary velocity fields in Alzheimer's disease neuroimaging initiative. Med Image Comput Comput Assist Interv 2009; 12(Pt 2): 240-7.
-
(2009)
Med Image Comput Comput Assist Interv
, vol.12
, Issue.PART 2
, pp. 240-247
-
-
Bossa, M.N.1
Zacur, E.2
Olmos, S.3
-
241
-
-
77954515677
-
Diagnostic utility of novel MRI-based biomarkers for Alzheimer's disease: Diffusion tensor imaging and deformation-based morphometry
-
Friese U, Meindl T, Herpertz SC, Reiser MF, Hampel H, Teipel SJ. Diagnostic utility of novel MRI-based biomarkers for Alzheimer's disease: diffusion tensor imaging and deformation-based morphometry. J Alzheimers Dis 2010; 20: 477-90.
-
(2010)
J Alzheimers Dis
, vol.20
, pp. 477-490
-
-
Friese, U.1
Meindl, T.2
Herpertz, S.C.3
Reiser, M.F.4
Hampel, H.5
Teipel, S.J.6
-
242
-
-
79956226416
-
Algorithms, atrophy and Alzheimer's disease: Cautionary tales for clinical trials
-
Fox NC, Ridgway GR, Schott JM. Algorithms, atrophy and Alzheimer's disease: cautionary tales for clinical trials. Neuroimage 2011; 57: 15-8.
-
(2011)
Neuroimage
, vol.57
, pp. 15-18
-
-
Fox, N.C.1
Ridgway, G.R.2
Schott, J.M.3
-
243
-
-
77956084058
-
Multicentre variability of MRIbased medial temporal lobe volumetry in Alzheimer's disease
-
Teipel SJ, Ewers M, Wolf S, et al. Multicentre variability of MRIbased medial temporal lobe volumetry in Alzheimer's disease. Psychiatry Res 2010; 182: 244-50.
-
(2010)
Psychiatry Res
, vol.182
, pp. 244-250
-
-
Teipel, S.J.1
Ewers, M.2
Wolf, S.3
-
244
-
-
81355150870
-
Atrophy and dysfunction of parahippocampal white matter in mild Alzheimer's disease
-
Wang C, Stebbins GT, Medina DA, et al. Atrophy and dysfunction of parahippocampal white matter in mild Alzheimer's disease. Neurobiol Aging 2012; 33: 43-52.
-
(2012)
Neurobiol Aging
, vol.33
, pp. 43-52
-
-
Wang, C.1
Stebbins, G.T.2
Medina, D.A.3
-
245
-
-
75149143609
-
Grey and white matter changes at different stages of Alzheimer's disease
-
Serra L, Cercignani M, Lenzi D, et al. Grey and white matter changes at different stages of Alzheimer's disease. J Alzheimers Dis 2010; 19: 147-59.
-
(2010)
J Alzheimers Dis
, vol.19
, pp. 147-159
-
-
Serra, L.1
Cercignani, M.2
Lenzi, D.3
-
246
-
-
0036869232
-
Diffusion-tensor MRI: Theory, experimental design and data analysis-a technical review
-
Basser PJ, Jones DK. Diffusion-tensor MRI: theory, experimental design and data analysis-a technical review. NMR Biomed 2002; 15: 456-67.
-
(2002)
NMR Biomed
, vol.15
, pp. 456-467
-
-
Basser, P.J.1
Jones, D.K.2
-
247
-
-
34447566915
-
Diffusion tensor MRI to investigate dementias: A brief review
-
Bozzali M, Cherubini A. Diffusion tensor MRI to investigate dementias: a brief review. Magn Reson Imaging 2007; 25: 969-77.
-
(2007)
Magn Reson Imaging
, vol.25
, pp. 969-977
-
-
Bozzali, M.1
Cherubini, A.2
-
248
-
-
37849020439
-
Diffusion tensor imaging in mild cognitive impairment and Alzheimer's disease: A review
-
Chua TC, Wen W, Slavin MJ, Sachdev PS. Diffusion tensor imaging in mild cognitive impairment and Alzheimer's disease: a review. Curr Opin Neurol 2008; 21: 83-92.
-
(2008)
Curr Opin Neurol
, vol.21
, pp. 83-92
-
-
Chua, T.C.1
Wen, W.2
Slavin, M.J.3
Sachdev, P.S.4
-
249
-
-
65249104526
-
Update on diffusion tensor imaging in Alzheimer's disease
-
Hess CP. Update on diffusion tensor imaging in Alzheimer's disease. Magn Reson Imaging Clin N Am 2009; 17: 215-24.
-
(2009)
Magn Reson Imaging Clin N Am
, vol.17
, pp. 215-224
-
-
Hess, C.P.1
-
250
-
-
35349015772
-
Diffusion-tensor MR imaging and tractography: Exploring brain microstructure and connectivity
-
Nucifora PG, Verma R, Lee SK, Melhem ER. Diffusion-tensor MR imaging and tractography: exploring brain microstructure and connectivity. Radiology 2007; 245: 367-84.
-
(2007)
Radiology
, vol.245
, pp. 367-384
-
-
Nucifora, P.G.1
Verma, R.2
Lee, S.K.3
Melhem, E.R.4
-
251
-
-
70249141259
-
Optic nerve and optic radiation neurodegeneration in patients with glaucoma: In vivo analysis with 3-T diffusion-tensor MR imaging
-
Garaci FG, Bolacchi F, Cerulli A, et al. Optic nerve and optic radiation neurodegeneration in patients with glaucoma: in vivo analysis with 3-T diffusion-tensor MR imaging. Radiology 2009; 252: 496-501.
-
(2009)
Radiology
, vol.252
, pp. 496-501
-
-
Garaci, F.G.1
Bolacchi, F.2
Cerulli, A.3
-
252
-
-
84859108582
-
Long-term cognitive and behavioral therapies, combined with augmentative communication, are related to uncinate fasciculus integrity in autism
-
Pardini M, Elia M, Garaci FG, et al. Long-term cognitive and behavioral therapies, combined with augmentative communication, are related to uncinate fasciculus integrity in autism. J Autism Dev Disord 2012; 42: 585-92.
-
(2012)
J Autism Dev Disord
, vol.42
, pp. 585-592
-
-
Pardini, M.1
Elia, M.2
Garaci, F.G.3
-
253
-
-
70350127199
-
White matter reduced streamline coherence in young men with autism and mental retardation
-
Pardini M, Garaci FG, Bonzano L, et al. White matter reduced streamline coherence in young men with autism and mental retardation. Eur J Neurol 2009; 16: 1185-90.
-
(2009)
Eur J Neurol
, vol.16
, pp. 1185-1190
-
-
Pardini, M.1
Garaci, F.G.2
Bonzano, L.3
-
255
-
-
49649099578
-
Studying connections in the living human brain with diffusion MRI
-
Jones DK. Studying connections in the living human brain with diffusion MRI. Cortex 2008; 44: 936-52.
-
(2008)
Cortex
, vol.44
, pp. 936-952
-
-
Jones, D.K.1
-
256
-
-
79958844599
-
Technical note: DTI measurements of fractional anisotropy and mean diffusivity at 1. 5 T: Comparison of two radiofrequency head coils with different functional designs and sensitivities
-
Giannelli M, Belmonte G, Toschi N, et al. Technical note: DTI measurements of fractional anisotropy and mean diffusivity at 1. 5 T: comparison of two radiofrequency head coils with different functional designs and sensitivities. Med Phys 2011; 38: 3205-11.
-
(2011)
Med Phys
, vol.38
, pp. 3205-3211
-
-
Giannelli, M.1
Belmonte, G.2
Toschi, N.3
-
257
-
-
33646488698
-
White matter changes in mild cognitive impairment and AD: A diffusion tensor imaging study
-
Medina D, Detoledo-Morrell L, Urresta F, et al. White matter changes in mild cognitive impairment and AD: A diffusion tensor imaging study. Neurobiol Aging 2006; 27: 663-72.
-
(2006)
Neurobiol Aging
, vol.27
, pp. 663-672
-
-
Medina, D.1
Detoledo-Morrell, L.2
Urresta, F.3
-
258
-
-
79960147521
-
Diffusion tensor imaging and Tract-Based Spatial Statistics in Alzheimer's disease and mild cognitive impairment
-
Liu Y, Spulber G, Lehtimaki KK, et al. Diffusion tensor imaging and Tract-Based Spatial Statistics in Alzheimer's disease and mild cognitive impairment. Neurobiol Aging 2011; 32: 1558-71.
-
(2011)
Neurobiol Aging
, vol.32
, pp. 1558-1571
-
-
Liu, Y.1
Spulber, G.2
Lehtimaki, K.K.3
-
260
-
-
70349664005
-
White matter hyperintensities and cognitive dysfunction in Alzheimer disease
-
Heo JH, Lee ST, Kon C, Park HJ, Shim JY, Kim M. White matter hyperintensities and cognitive dysfunction in Alzheimer disease. J Geriatr Psychiatry Neurol 2009; 22: 207-12.
-
(2009)
J Geriatr Psychiatry Neurol
, vol.22
, pp. 207-212
-
-
Heo, J.H.1
Lee, S.T.2
Kon, C.3
Park, H.J.4
Shim, J.Y.5
Kim, M.6
-
261
-
-
82755193710
-
Staging Alzheimer's disease progression with multimodality neuroimaging
-
Ewers M, Frisoni GB, Teipel SJ, et al. Staging Alzheimer's disease progression with multimodality neuroimaging. Prog Neurobiol 2011; 95: 535-46.
-
(2011)
Prog Neurobiol
, vol.95
, pp. 535-546
-
-
Ewers, M.1
Frisoni, G.B.2
Teipel, S.J.3
-
262
-
-
68049105379
-
Diffusion tensor imaging of the posterior cingulate is a useful biomarker of mild cognitive impairment
-
Chua TC, Wen W, Chen X, et al. Diffusion tensor imaging of the posterior cingulate is a useful biomarker of mild cognitive impairment. Am J Geriatr Psychiatry 2009; 17: 602-13.
-
(2009)
Am J Geriatr Psychiatry
, vol.17
, pp. 602-613
-
-
Chua, T.C.1
Wen, W.2
Chen, X.3
-
263
-
-
0037174781
-
Selective reduction of diffusion anisotropy in white matter of Alzheimer disease brains measured by 3. 0 Tesla magnetic resonance imaging
-
Takahashi S, Yonezawa H, Takahashi J, Kudo M, Inoue T, Tohgi H. Selective reduction of diffusion anisotropy in white matter of Alzheimer disease brains measured by 3. 0 Tesla magnetic resonance imaging. Neurosci Lett 2002; 332: 45-8.
-
(2002)
Neurosci Lett
, vol.332
, pp. 45-48
-
-
Takahashi, S.1
Yonezawa, H.2
Takahashi, J.3
Kudo, M.4
Inoue, T.5
Tohgi, H.6
-
264
-
-
33846112012
-
Diffusion tensor imaging of cingulum fibers in mild cognitive impairment and Alzheimer disease
-
Zhang Y, Schuff N, Jahng GH, et al. Diffusion tensor imaging of cingulum fibers in mild cognitive impairment and Alzheimer disease. Neurology 2007; 68: 13-9.
-
(2007)
Neurology
, vol.68
, pp. 13-19
-
-
Zhang, Y.1
Schuff, N.2
Jahng, G.H.3
-
265
-
-
77955310026
-
White matter integrity in mild cognitive impairment: A tract-based spatial statistics study
-
Zhuang L, Wen W, Zhu W, et al. White matter integrity in mild cognitive impairment: a tract-based spatial statistics study. Neuroimage 2010; 53: 16-25.
-
(2010)
Neuroimage
, vol.53
, pp. 16-25
-
-
Zhuang, L.1
Wen, W.2
Zhu, W.3
-
266
-
-
79952253376
-
A meta-analysis of diffusion tensor imaging in mild cognitive impairment and Alzheimer's disease
-
Sexton CE, Kalu UG, Filippini N, Mackay CE, Ebmeier KP. A meta-analysis of diffusion tensor imaging in mild cognitive impairment and Alzheimer's disease. Neurobiol Aging 2011; 32: 2322e5-18.
-
(2011)
Neurobiol Aging
, vol.32
-
-
Sexton, C.E.1
Kalu, U.G.2
Filippini, N.3
Mackay, C.E.4
Ebmeier, K.P.5
-
267
-
-
79952070775
-
DTI measures in crossingfibre areas: Increased diffusion anisotropy reveals early white matter alteration in MCI and mild Alzheimer's disease
-
Douaud G, Jbabdi S, Behrens TE, et al. DTI measures in crossingfibre areas: increased diffusion anisotropy reveals early white matter alteration in MCI and mild Alzheimer's disease. Neuroimage 2011; 55: 880-90.
-
(2011)
Neuroimage
, vol.55
, pp. 880-890
-
-
Douaud, G.1
Jbabdi, S.2
Behrens, T.E.3
-
268
-
-
30344463825
-
Orthogonal tensor invariants and the analysis of diffusion tensor magnetic resonance images
-
Ennis DB, Kindlmann G. Orthogonal tensor invariants and the analysis of diffusion tensor magnetic resonance images. Magn Reson Med 2006; 55: 136-46.
-
(2006)
Magn Reson Med
, vol.55
, pp. 136-146
-
-
Ennis, D.B.1
Kindlmann, G.2
-
269
-
-
60149083951
-
Decreased white matter integrity in late-myelinating fiber pathways in Alzheimer's disease supports retrogenesis
-
Stricker NH, Schweinsburg BC, Delano-Wood L, et al. Decreased white matter integrity in late-myelinating fiber pathways in Alzheimer's disease supports retrogenesis. Neuroimage 2009; 45: 10-6.
-
(2009)
Neuroimage
, vol.45
, pp. 10-16
-
-
Stricker, N.H.1
Schweinsburg, B.C.2
Delano-Wood, L.3
-
270
-
-
33947173843
-
Multivariate network analysis of fiber tract integrity in Alzheimer's disease
-
Teipel SJ, Stahl R, Dietrich O, et al. Multivariate network analysis of fiber tract integrity in Alzheimer's disease. Neuroimage 2007; 34: 985-95.
-
(2007)
Neuroimage
, vol.34
, pp. 985-995
-
-
Teipel, S.J.1
Stahl, R.2
Dietrich, O.3
-
271
-
-
34447647287
-
Morphological substrate of face matching in healthy ageing and mild cognitive impairment: A combined MRI-fMRI study
-
Teipel SJ, Bokde AL, Born C, et al. Morphological substrate of face matching in healthy ageing and mild cognitive impairment: a combined MRI-fMRI study. Brain 2007; 130(Pt 7): 1745-58.
-
(2007)
Brain
, vol.130
, Issue.PART 7
, pp. 1745-1758
-
-
Teipel, S.J.1
Bokde, A.L.2
Born, C.3
-
272
-
-
79958777483
-
The search for neuroimaging biomarkers of Alzheimer's disease with advanced MRI techniques
-
Li TQ, Wahlund LO. The search for neuroimaging biomarkers of Alzheimer's disease with advanced MRI techniques. Acta Radiol 2011; 52: 211-22.
-
(2011)
Acta Radiol
, vol.52
, pp. 211-222
-
-
Li, T.Q.1
Wahlund, L.O.2
-
273
-
-
61449238161
-
Hippocampal volumes, proton magnetic resonance spectroscopy metabolites, and cerebrovascular disease in mild cognitive impairment subtypes
-
Kantarci K, Petersen RC, Przybelski SA, et al. Hippocampal volumes, proton magnetic resonance spectroscopy metabolites, and cerebrovascular disease in mild cognitive impairment subtypes. Arch Neurol 2008; 65: 1621-8.
-
(2008)
Arch Neurol
, vol.65
, pp. 1621-1628
-
-
Kantarci, K.1
Petersen, R.C.2
Przybelski, S.A.3
-
274
-
-
33749504441
-
Evaluation of treatment effects in Alzheimer's and other neurodegenerative diseases by MRI and MRS
-
Mueller SG, Schuff N, Weiner MW. Evaluation of treatment effects in Alzheimer's and other neurodegenerative diseases by MRI and MRS. NMR Biomed 2006; 19: 655-68.
-
(2006)
NMR Biomed
, vol.19
, pp. 655-668
-
-
Mueller, S.G.1
Schuff, N.2
Weiner, M.W.3
-
275
-
-
0034680078
-
Patterns of brain activation in people at risk for Alzheimer's disease
-
Bookheimer SY, Strojwas MH, Cohen MS, et al. Patterns of brain activation in people at risk for Alzheimer's disease. N Engl J Med 2000; 343: 450-6.
-
(2000)
N Engl J Med
, vol.343
, pp. 450-456
-
-
Bookheimer, S.Y.1
Strojwas, M.H.2
Cohen, M.S.3
-
276
-
-
43849094939
-
Altered medial temporal lobe responses during visuospatial encoding in healthy APOE*4 carriers
-
Borghesani PR, Johnson LC, Shelton AL, et al. Altered medial temporal lobe responses during visuospatial encoding in healthy APOE*4 carriers. Neurobiol Aging 2008; 29: 981-91.
-
(2008)
Neurobiol Aging
, vol.29
, pp. 981-991
-
-
Borghesani, P.R.1
Johnson, L.C.2
Shelton, A.L.3
-
277
-
-
66349129276
-
Distinct patterns of brain activity in young carriers of the APOE-epsilon 4 allele
-
Filippini N, MacIntosh BJ, Hough MG, et al. Distinct patterns of brain activity in young carriers of the APOE-epsilon 4 allele. Proc Natl Acad Sci USA 2009; 106: 7209-14.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 7209-7214
-
-
Filippini, N.1
McIntosh, B.J.2
Hough, M.G.3
-
278
-
-
16844374815
-
Memory encoding in Alzheimer's disease: An fMRI study of explicit and implicit memory
-
Golby A, Silverberg G, Race E, et al. Memory encoding in Alzheimer's disease: an fMRI study of explicit and implicit memory. Brain 2005; 128(Pt 4): 773-87.
-
(2005)
Brain
, vol.128
, Issue.PART 4
, pp. 773-787
-
-
Golby, A.1
Silverberg, G.2
Race, E.3
-
279
-
-
0035675646
-
Hippocampal activations during repetitive learning and recall of geometric patterns
-
Gron G, Bittner D, Schmitz B, Wunderlich AP, Tomczak R, Riepe MW. Hippocampal activations during repetitive learning and recall of geometric patterns. Learn Mem 2001; 8: 336-45.
-
(2001)
Learn Mem
, vol.8
, pp. 336-345
-
-
Gron, G.1
Bittner, D.2
Schmitz, B.3
Wunderlich, A.P.4
Tomczak, R.5
Riepe, M.W.6
-
280
-
-
35148881227
-
Increased fMRI responses during encoding in mild cognitive impairment
-
Hamalainen A, Pihlajamaki M, Tanila H, et al. Increased fMRI responses during encoding in mild cognitive impairment. Neurobiol Aging 2007; 28: 1889-903.
-
(2007)
Neurobiol Aging
, vol.28
, pp. 1889-1903
-
-
Hamalainen, A.1
Pihlajamaki, M.2
Tanila, H.3
-
281
-
-
34247556163
-
Functional MRI studies of associative encoding in normal aging, mild cognitive impairment, and Alzheimer's disease
-
Sperling R. Functional MRI studies of associative encoding in normal aging, mild cognitive impairment, and Alzheimer's disease. Ann N Y Acad Sci 2007; 1097: 146-55.
-
(2007)
Ann N Y Acad Sci
, vol.1097
, pp. 146-155
-
-
Sperling, R.1
-
282
-
-
77952496309
-
Functional alterations in memory networks in early Alzheimer's disease
-
Sperling RA, Dickerson BC, Pihlajamaki M, et al. Functional alterations in memory networks in early Alzheimer's disease. Neuromolecular Med 2010; 12: 27-43.
-
(2010)
Neuromolecular Med
, vol.12
, pp. 27-43
-
-
Sperling, R.A.1
Dickerson, B.C.2
Pihlajamaki, M.3
-
283
-
-
33749522545
-
Alterations in memory networks in mild cognitive impairment and Alzheimer's disease: An independent component analysis
-
Celone KA, Calhoun VD, Dickerson BC, et al. Alterations in memory networks in mild cognitive impairment and Alzheimer's disease: an independent component analysis. J Neurosci 2006; 26: 10222-31.
-
(2006)
J Neurosci
, vol.26
, pp. 10222-10231
-
-
Celone, K.A.1
Calhoun, V.D.2
Dickerson, B.C.3
-
284
-
-
33748353456
-
Activation of brain regions vulnerable to Alzheimer's disease: The effect of mild cognitive impairment
-
Johnson SC, Schmitz TW, Moritz CH, Meyerand ME, Rowley HA, Alexander AL, et al. Activation of brain regions vulnerable to Alzheimer's disease: the effect of mild cognitive impairment. Neurobiol Aging 2006; 27: 1604-12.
-
(2006)
Neurobiol Aging
, vol.27
, pp. 1604-1612
-
-
Johnson, S.C.1
Schmitz, T.W.2
Moritz, C.H.3
Meyerand, M.E.4
Rowley, H.A.5
Alexander, A.L.6
-
285
-
-
34548683940
-
Cortical deactivation in mild cognitive impairment: High-field-strength functional MR imaging
-
Petrella JR, Wang L, Krishnan S, et al. Cortical deactivation in mild cognitive impairment: high-field-strength functional MR imaging. Radiology 2007; 245: 224-35.
-
(2007)
Radiology
, vol.245
, pp. 224-235
-
-
Petrella, J.R.1
Wang, L.2
Krishnan, S.3
-
286
-
-
34548534069
-
Unrest at rest: Default activity and spontaneous network correlations
-
Buckner RL, Vincent JL. Unrest at rest: default activity and spontaneous network correlations. Neuroimage 2007; 37: 1091-6.
-
(2007)
Neuroimage
, vol.37
, pp. 1091-1096
-
-
Buckner, R.L.1
Vincent, J.L.2
-
287
-
-
79960195244
-
Age and amyloid-related alterations in default network habituation to stimulus repetition
-
Feb 17
-
Vannini P, Hedden T, Becker JA, et al. Age and amyloid-related alterations in default network habituation to stimulus repetition. Neurobiol Aging 2011 Feb 17.
-
(2011)
Neurobiol Aging
-
-
Vannini, P.1
Hedden, T.2
Becker, J.A.3
-
288
-
-
67651054970
-
Resting-state BOLD networks versus task-associated functional MRI for distinguishing Alzheimer's disease risk groups
-
Fleisher AS, Sherzai A, Taylor C, Langbaum JB, Chen K, Buxton RB. Resting-state BOLD networks versus task-associated functional MRI for distinguishing Alzheimer's disease risk groups. Neuroimage 2009; 47: 1678-90.
-
(2009)
Neuroimage
, vol.47
, pp. 1678-1690
-
-
Fleisher, A.S.1
Sherzai, A.2
Taylor, C.3
Langbaum, J.B.4
Chen, K.5
Buxton, R.B.6
-
289
-
-
78751649250
-
Failure of repetition suppression and memory encoding in aging and Alzheimer's disease
-
Pihlajamaki M, O'Keefe K, O'Brien J, Blacker D, Sperling RA. Failure of repetition suppression and memory encoding in aging and Alzheimer's disease. Brain Imaging Behav 2011; 5: 36-44.
-
(2011)
Brain Imaging Behav
, vol.5
, pp. 36-44
-
-
Pihlajamaki, M.1
O'Keefe, K.2
O'Brien, J.3
Blacker, D.4
Sperling, R.A.5
-
290
-
-
77949449525
-
Evidence of altered posteromedial cortical FMRI activity in subjects at risk for Alzheimer disease
-
Pihlajamaki M, O' Keefe K, Bertram L, et al. Evidence of altered posteromedial cortical FMRI activity in subjects at risk for Alzheimer disease. Alzheimer Dis Assoc Disord 2010; 24: 28-36.
-
(2010)
Alzheimer Dis Assoc Disord
, vol.24
, pp. 28-36
-
-
Pihlajamaki, M.1
O' Keefe, K.2
Bertram, L.3
-
291
-
-
47249145329
-
Impaired medial temporal repetition suppression is related to failure of parietal deactivation in Alzheimer disease
-
Pihlajamaki M, DePeau KM, Blacker D, Sperling RA. Impaired medial temporal repetition suppression is related to failure of parietal deactivation in Alzheimer disease. Am J Geriatr Psychiatry 2008; 16: 283-92.
-
(2008)
Am J Geriatr Psychiatry
, vol.16
, pp. 283-292
-
-
Pihlajamaki, M.1
DePeau, K.M.2
Blacker, D.3
Sperling, R.A.4
-
292
-
-
1842427969
-
Default-mode network activity distinguishes Alzheimer's disease from healthy aging: Evidence from functional MRI
-
Greicius MD, Srivastava G, Reiss AL, Menon V. Default-mode network activity distinguishes Alzheimer's disease from healthy aging: evidence from functional MRI. Proc Natl Acad Sci USA 2004; 101: 4637-42.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 4637-4642
-
-
Greicius, M.D.1
Srivastava, G.2
Reiss, A.L.3
Menon, V.4
-
293
-
-
57749172272
-
Resting-state functional connectivity reflects structural connectivity in the default mode network
-
Greicius MD, Supekar K, Menon V, Dougherty RF. Resting-state functional connectivity reflects structural connectivity in the default mode network. Cereb Cortex 2009; 19: 72-8.
-
(2009)
Cereb Cortex
, vol.19
, pp. 72-78
-
-
Greicius, M.D.1
Supekar, K.2
Menon, V.3
Dougherty, R.F.4
-
294
-
-
36749045805
-
Selective changes of restingstate networks in individuals at risk for Alzheimer's disease
-
Sorg C, Riedl V, Muhlau M, et al. Selective changes of restingstate networks in individuals at risk for Alzheimer's disease. Proc Natl Acad Sci USA 2007; 104: 18760-5.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 18760-18765
-
-
Sorg, C.1
Riedl, V.2
Muhlau, M.3
-
295
-
-
35148890661
-
Altered functional connectivity in early Alzheimer's disease: A resting-state fMRI study
-
Wang K, Liang M, Wang L, et al. Altered functional connectivity in early Alzheimer's disease: a resting-state fMRI study. Hum Brain Mapp 2007; 28: 967-78.
-
(2007)
Hum Brain Mapp
, vol.28
, pp. 967-978
-
-
Wang, K.1
Liang, M.2
Wang, L.3
-
296
-
-
41149157850
-
A new integrative model of cerebral activation, deactivation and default mode function in Alzheimer's disease
-
Wermke M, Sorg C, Wohlschlager AM, Drzezga A. A new integrative model of cerebral activation, deactivation and default mode function in Alzheimer's disease. Eur J Nucl Med Mol Imaging 2008; 35(Suppl 1): S12-24.
-
(2008)
Eur J Nucl Med Mol Imaging
, vol.35
, Issue.SUPPL. 1
-
-
Wermke, M.1
Sorg, C.2
Wohlschlager, A.M.3
Drzezga, A.4
-
297
-
-
79951589032
-
Default mode network connectivity in stable vs progressive mild cognitive impairment
-
Petrella JR, Sheldon FC, Prince SE, Calhoun VD, Doraiswamy PM. Default mode network connectivity in stable vs progressive mild cognitive impairment. Neurology 2011; 76: 511-7.
-
(2011)
Neurology
, vol.76
, pp. 511-517
-
-
Petrella, J.R.1
Sheldon, F.C.2
Prince, S.E.3
Calhoun, V.D.4
Doraiswamy, P.M.5
-
298
-
-
14244263525
-
Fractional Gaussian noise, functional MRI and Alzheimer's disease
-
Maxim V, Sendur L, Fadili J, et al. Fractional Gaussian noise, functional MRI and Alzheimer's disease. Neuroimage 2005; 25: 141-58.
-
(2005)
Neuroimage
, vol.25
, pp. 141-158
-
-
Maxim, V.1
Sendur, L.2
Fadili, J.3
-
299
-
-
80054863744
-
Inter-individual differences in fMRI entropy measurements in old age
-
Sokunbi MO, Staff RT, Waiter GD, et al. Inter-individual differences in fMRI entropy measurements in old age. IEEE Trans Biomed Eng 2011; 58: 3206-14.
-
(2011)
IEEE Trans Biomed Eng
, vol.58
, pp. 3206-3214
-
-
Sokunbi, M.O.1
Staff, R.T.2
Waiter, G.D.3
-
300
-
-
13844280982
-
Disturbed fluctuations of resting state EEG synchronization in Alzheimer's disease
-
Stam CJ, Montez T, Jones BF, et al. Disturbed fluctuations of resting state EEG synchronization in Alzheimer's disease. Clin Neurophysiol 2005; 116: 708-15.
-
(2005)
Clin Neurophysiol
, vol.116
, pp. 708-715
-
-
Stam, C.J.1
Montez, T.2
Jones, B.F.3
-
301
-
-
80051663721
-
Functional network disruption in the degenerative dementias
-
Pievani M, de HW, Wu T, Seeley WW, Frisoni GB. Functional network disruption in the degenerative dementias. Lancet Neurol 2011; 10: 829-43.
-
(2011)
Lancet Neurol
, vol.10
, pp. 829-843
-
-
Pievani, M.1
de, H.W.2
Wu, T.3
Seeley, W.W.4
Frisoni, G.B.5
-
302
-
-
67649321879
-
Cholinergic stimulation enhances neural activity associated with encoding but reduces neural activity associated with retrieval in humans
-
Kukolja J, Thiel CM, Fink GR. Cholinergic stimulation enhances neural activity associated with encoding but reduces neural activity associated with retrieval in humans. J Neurosci 2009; 29: 8119-28.
-
(2009)
J Neurosci
, vol.29
, pp. 8119-8128
-
-
Kukolja, J.1
Thiel, C.M.2
Fink, G.R.3
-
303
-
-
30344460006
-
Cholinergic challenge in Alzheimer patients and mild cognitive impairment differentially affects hippocampal activation--a pharmacological fMRI study
-
Goekoop R, Scheltens P, Barkhof F, Rombouts SA. Cholinergic challenge in Alzheimer patients and mild cognitive impairment differentially affects hippocampal activation--a pharmacological fMRI study. Brain 2006; 129(Pt 1): 141-57.
-
(2006)
Brain
, vol.129
, Issue.PART 1
, pp. 141-157
-
-
Goekoop, R.1
Scheltens, P.2
Barkhof, F.3
Rombouts, S.A.4
-
304
-
-
0036901184
-
Alterations in brain activation during cholinergic enhancement with rivastigmine in Alzheimer's disease
-
Rombouts SA, Barkhof F, Van Meel CS, Scheltens P. Alterations in brain activation during cholinergic enhancement with rivastigmine in Alzheimer's disease. J Neurol Neurosurg Psychiatry 2002; 73: 665-71.
-
(2002)
J Neurol Neurosurg Psychiatry
, vol.73
, pp. 665-671
-
-
Rombouts, S.A.1
Barkhof, F.2
Van Meel, C.S.3
Scheltens, P.4
-
305
-
-
3142547230
-
Cholinergic enhancement of frontal lobe activity in mild cognitive impairment
-
Saykin AJ, Wishart HA, Rabin LA, et al. Cholinergic enhancement of frontal lobe activity in mild cognitive impairment. Brain 2004; 127(Pt 7): 1574-83.
-
(2004)
Brain
, vol.127
, Issue.PART 7
, pp. 1574-1583
-
-
Saykin, A.J.1
Wishart, H.A.2
Rabin, L.A.3
-
306
-
-
34447566919
-
Regional brain activity after prolonged cholinergic enhancement in early Alzheimer's disease
-
Shanks MF, McGeown WJ, Forbes-McKay KE, Waiter GD, Ries M, Venneri A. Regional brain activity after prolonged cholinergic enhancement in early Alzheimer's disease. Magn Reson Imaging 2007; 25: 848-59.
-
(2007)
Magn Reson Imaging
, vol.25
, pp. 848-859
-
-
Shanks, M.F.1
McGeown, W.J.2
Forbes-McKay, K.E.3
Waiter, G.D.4
Ries, M.5
Venneri, A.6
-
307
-
-
80955137860
-
Potential of functional MRI as a biomarker in early Alzheimer's disease
-
Sperling R. Potential of functional MRI as a biomarker in early Alzheimer's disease. Neurobiol Aging 2011; 32(Suppl 1): S37-43.
-
(2011)
Neurobiol Aging
, vol.32
, Issue.SUPPL. 1
-
-
Sperling, R.1
-
308
-
-
13944258543
-
PET imaging in the assessment of normal and impaired cognitive function
-
Silverman DH, Alavi A. PET imaging in the assessment of normal and impaired cognitive function. Radiol Clin North Am 2005; 43: 67-77, x.
-
(2005)
Radiol Clin North Am
, vol.43
-
-
Silverman, D.H.1
Alavi, A.2
-
309
-
-
4444281876
-
Magnetic resonance and PET studies in the early diagnosis of Alzheimer's disease
-
Mosconi L, De SS, Rusinek H, Convit A, de Leon MJ. Magnetic resonance and PET studies in the early diagnosis of Alzheimer's disease. Expert Rev Neurother 2004; 4: 831-49.
-
(2004)
Expert Rev Neurother
, vol.4
, pp. 831-849
-
-
Mosconi, L.1
De, S.S.2
Rusinek, H.3
Convit, A.4
de Leon, M.J.5
-
310
-
-
77953536045
-
Surface featureguided mapping of cerebral metabolic changes in cognitively normal and mildly impaired elderly
-
Apostolova LG, Thompson PM, Rogers SA, et al. Surface featureguided mapping of cerebral metabolic changes in cognitively normal and mildly impaired elderly. Mol Imaging Biol 2010; 12(2): 218-24.
-
(2010)
Mol Imaging Biol
, vol.12
, Issue.2
, pp. 218-224
-
-
Apostolova, L.G.1
Thompson, P.M.2
Rogers, S.A.3
-
311
-
-
10744232413
-
Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound-B
-
Klunk WE, Engler H, Nordberg A, et al. Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound-B. Ann Neurol 2004; 55: 306-19.
-
(2004)
Ann Neurol
, vol.55
, pp. 306-319
-
-
Klunk, W.E.1
Engler, H.2
Nordberg, A.3
-
313
-
-
33747048954
-
[11C]PIB in a nondemented population: Potential antecedent marker of Alzheimer disease
-
Mintun MA, Larossa GN, Sheline YI, et al. [11C]PIB in a nondemented population: potential antecedent marker of Alzheimer disease. Neurology 2006; 67: 446-52.
-
(2006)
Neurology
, vol.67
, pp. 446-452
-
-
Mintun, M.A.1
Larossa, G.N.2
Sheline, Y.I.3
-
315
-
-
77955846423
-
Plaque and tangle imaging and cognition in normal aging and Alzheimer's disease
-
Braskie MN, Klunder AD, Hayashi KM, et al. Plaque and tangle imaging and cognition in normal aging and Alzheimer's disease. Neurobiol Aging 2010; 31: 1669-78.
-
(2010)
Neurobiol Aging
, vol.31
, pp. 1669-1678
-
-
Braskie, M.N.1
Klunder, A.D.2
Hayashi, K.M.3
-
316
-
-
70349971921
-
FDDNP binding using MR derived cortical surface maps
-
Protas HD, Huang SC, Kepe V, et al. FDDNP binding using MR derived cortical surface maps. Neuroimage 2010; 49: 240-8.
-
(2010)
Neuroimage
, vol.49
, pp. 240-248
-
-
Protas, H.D.1
Huang, S.C.2
Kepe, V.3
-
317
-
-
55949117032
-
Frequent amyloid deposition without significant cognitive impairment among the elderly
-
Aizenstein HJ, Nebes RD, Saxton JA, et al. Frequent amyloid deposition without significant cognitive impairment among the elderly. Arch Neurol 2008; 65: 1509-17.
-
(2008)
Arch Neurol
, vol.65
, pp. 1509-1517
-
-
Aizenstein, H.J.1
Nebes, R.D.2
Saxton, J.A.3
-
318
-
-
78049427912
-
Progression of cerebral amyloid load is associated with the apolipoprotein E epsilon4 genotype in Alzheimer's disease
-
Grimmer T, Tholen S, Yousefi BH, et al. Progression of cerebral amyloid load is associated with the apolipoprotein E epsilon4 genotype in Alzheimer's disease. Biol Psychiatry 2010; 68: 879-84.
-
(2010)
Biol Psychiatry
, vol.68
, pp. 879-884
-
-
Grimmer, T.1
Tholen, S.2
Yousefi, B.H.3
-
319
-
-
33749506795
-
Two-year follow-up of amyloid deposition in patients with Alzheimer's disease
-
Engler H, Forsberg A, Almkvist O, et al. Two-year follow-up of amyloid deposition in patients with Alzheimer's disease. Brain 2006; 129(Pt 11): 2856-66.
-
(2006)
Brain
, vol.129
, Issue.PART 11
, pp. 2856-2866
-
-
Engler, H.1
Forsberg, A.2
Almkvist, O.3
-
320
-
-
77957072855
-
Target-specific PET probes for neurodegenerative disorders related to dementia
-
Kadir A, Nordberg A. Target-specific PET probes for neurodegenerative disorders related to dementia. J Nucl Med 2010; 51: 1418-30.
-
(2010)
J Nucl Med
, vol.51
, pp. 1418-1430
-
-
Kadir, A.1
Nordberg, A.2
-
321
-
-
33845707784
-
PET of brain amyloid and tau in mild cognitive impairment
-
Small GW, Kepe V, Ercoli LM, et al. PET of brain amyloid and tau in mild cognitive impairment. N Engl J Med 2006; 355: 2652-63.
-
(2006)
N Engl J Med
, vol.355
, pp. 2652-2663
-
-
Small, G.W.1
Kepe, V.2
Ercoli, L.M.3
-
322
-
-
0035035603
-
Analysis of partial volume effects in diffusion-tensor MRI
-
Alexander AL, Hasan KM, Lazar M, Tsuruda JS, Parker DL. Analysis of partial volume effects in diffusion-tensor MRI. Magn Reson Med 2001; 45: 770-80.
-
(2001)
Magn Reson Med
, vol.45
, pp. 770-780
-
-
Alexander, A.L.1
Hasan, K.M.2
Lazar, M.3
Tsuruda, J.S.4
Parker, D.L.5
-
323
-
-
44649165640
-
Diffusion spectrum magnetic resonance imaging (DSI) tractography of crossing fibers
-
Wedeen VJ, Wang RP, Schmahmann JD, et al. Diffusion spectrum magnetic resonance imaging (DSI) tractography of crossing fibers. Neuroimage 2008; 41: 1267-77.
-
(2008)
Neuroimage
, vol.41
, pp. 1267-1277
-
-
Wedeen, V.J.1
Wang, R.P.2
Schmahmann, J.D.3
-
324
-
-
79960619279
-
White matter characterization with diffusional kurtosis imaging
-
Fieremans E, Jensen JH, Helpern JA. White matter characterization with diffusional kurtosis imaging. Neuroimage 2011; 58: 177-88.
-
(2011)
Neuroimage
, vol.58
, pp. 177-188
-
-
Fieremans, E.1
Jensen, J.H.2
Helpern, J.A.3
-
325
-
-
61849164596
-
Advanced MR diffusion characterization of neural tissue using directional diffusion kurtosis analysis
-
Hui ES, Cheung MM, Qi L, Wu EX. Advanced MR diffusion characterization of neural tissue using directional diffusion kurtosis analysis. Conf Proc IEEE Eng Med Biol Soc 2008; 2008: 3941-4.
-
(2008)
Conf Proc IEEE Eng Med Biol Soc
, vol.2008
, pp. 3941-3944
-
-
Hui, E.S.1
Cheung, M.M.2
Qi, L.3
Wu, E.X.4
-
326
-
-
77955660153
-
MRI quantification of non-Gaussian water diffusion by kurtosis analysis
-
Jensen JH, Helpern JA. MRI quantification of non-Gaussian water diffusion by kurtosis analysis. NMR Biomed 2010; 23: 698-710.
-
(2010)
NMR Biomed
, vol.23
, pp. 698-710
-
-
Jensen, J.H.1
Helpern, J.A.2
-
327
-
-
26444574077
-
Multiple-fiber reconstruction algorithms for diffusion MRI
-
Alexander DC. Multiple-fiber reconstruction algorithms for diffusion MRI. Ann N Y Acad Sci 2005; 1064: 113-33.
-
(2005)
Ann N Y Acad Sci
, vol.1064
, pp. 113-133
-
-
Alexander, D.C.1
-
328
-
-
44949264013
-
AxCaliber: A method for measuring axon diameter distribution from diffusion MRI
-
Assaf Y, Blumenfeld-Katzir T, Yovel Y, Basser PJ. AxCaliber: a method for measuring axon diameter distribution from diffusion MRI. Magn Reson Med 2008; 59: 1347-54.
-
(2008)
Magn Reson Med
, vol.59
, pp. 1347-1354
-
-
Assaf, Y.1
Blumenfeld-Katzir, T.2
Yovel, Y.3
Basser, P.J.4
-
329
-
-
22044439126
-
Composite hindered and restricted model of diffusion (CHARMED) MR imaging of the human brain
-
Assaf Y, Basser PJ. Composite hindered and restricted model of diffusion (CHARMED) MR imaging of the human brain. Neuroimage 2005; 27: 48-58.
-
(2005)
Neuroimage
, vol.27
, pp. 48-58
-
-
Assaf, Y.1
Basser, P.J.2
-
330
-
-
77954959460
-
Orientationally invariant indices of axon diameter and density from diffusion MRI
-
Alexander DC, Hubbard PL, Hall MG, et al. Orientationally invariant indices of axon diameter and density from diffusion MRI. Neuroimage 2010; 52: 1374-89.
-
(2010)
Neuroimage
, vol.52
, pp. 1374-1389
-
-
Alexander, D.C.1
Hubbard, P.L.2
Hall, M.G.3
-
331
-
-
79952806370
-
Anisotropic anomalous diffusion assessed in the human brain by scalar invariant indices
-
De-Santis S., Gabrielli A, Bozzali M, Maraviglia B, Macaluso E, Capuani S. Anisotropic anomalous diffusion assessed in the human brain by scalar invariant indices. Magn Reson Med 2011; 65: 1043-52.
-
(2011)
Magn Reson Med
, vol.65
, pp. 1043-1052
-
-
De-Santis, S.1
Gabrielli, A.2
Bozzali, M.3
Maraviglia, B.4
Macaluso, E.5
Capuani, S.6
-
332
-
-
82455188087
-
Non-Gaussian diffusion imaging: A brief practical review
-
De-Santis S., Gabrielli A, Palombo M, Maraviglia B, Capuani S. Non-Gaussian diffusion imaging: a brief practical review. Magn Reson Imaging 2011; 29: 1410-6.
-
(2011)
Magn Reson Imaging
, vol.29
, pp. 1410-1416
-
-
De-Santis, S.1
Gabrielli, A.2
Palombo, M.3
Maraviglia, B.4
Capuani, S.5
-
334
-
-
84862629909
-
Diffusion kurtosis imaging discriminates patients with white matter lesions from healthy subjects
-
Iraji A, Davoodi-Bojd E, Soltanazian-Zadeh H, Hossein-Zadeh G, Jiang Q. Diffusion kurtosis imaging discriminates patients with white matter lesions from healthy subjects. Conf Proc IEEE Eng Med Biol Soc 2011; 2011: 2796-9.
-
(2011)
Conf Proc IEEE Eng Med Biol Soc
, vol.2011
, pp. 2796-2799
-
-
Iraji, A.1
Davoodi-Bojd, E.2
Soltanazian-Zadeh, H.3
Hossein-Zadeh, G.4
Jiang, Q.5
-
335
-
-
57049092242
-
Age-related non-Gaussian diffusion patterns in the prefrontal brain
-
Falangola MF, Jensen JH, Babb JS, et al. Age-related non-Gaussian diffusion patterns in the prefrontal brain. J Magn Reson Imaging 2008; 28: 1345-50.
-
(2008)
J Magn Reson Imaging
, vol.28
, pp. 1345-1350
-
-
Falangola, M.F.1
Jensen, J.H.2
Babb, J.S.3
-
336
-
-
80053081988
-
Parkinson disease: Diagnostic utility of diffusion kurtosis imaging
-
Wang JJ, Lin WY, Lu CS, et al. Parkinson disease: diagnostic utility of diffusion kurtosis imaging. Radiology 2011; 261: 210-7.
-
(2011)
Radiology
, vol.261
, pp. 210-217
-
-
Wang, J.J.1
Lin, W.Y.2
Lu, C.S.3
-
337
-
-
33751111992
-
Biological parametric mapping: A statistical toolbox for multimodality brain image analysis
-
Casanova R, Srikanth R, Baer A, et al. Biological parametric mapping: A statistical toolbox for multimodality brain image analysis. Neuroimage 2007; 34: 137-43.
-
(2007)
Neuroimage
, vol.34
, pp. 137-143
-
-
Casanova, R.1
Srikanth, R.2
Baer, A.3
-
338
-
-
34547399211
-
Integrating VBM into the General Linear Model with voxelwise anatomical covariates
-
Oakes TR, Fox AS, Johnstone T, Chung MK, Kalin N, Davidson RJ. Integrating VBM into the General Linear Model with voxelwise anatomical covariates. Neuroimage 2007; 34: 500-8.
-
(2007)
Neuroimage
, vol.34
, pp. 500-508
-
-
Oakes, T.R.1
Fox, A.S.2
Johnstone, T.3
Chung, M.K.4
Kalin, N.5
Davidson, R.J.6
-
339
-
-
79958769041
-
Biological parametric mapping with robust and non-parametric statistics
-
Yang X, Beason-Held L, Resnick SM, Landman BA. Biological parametric mapping with robust and non-parametric statistics. Neuroimage 2011; 57: 423-30.
-
(2011)
Neuroimage
, vol.57
, pp. 423-430
-
-
Yang, X.1
Beason-Held, L.2
Resnick, S.M.3
Landman, B.A.4
-
340
-
-
65549097795
-
A review of group ICA for fMRI data and ICA for joint inference of imaging, genetic, and ERP data
-
Calhoun VD, Liu J, Adali T. A review of group ICA for fMRI data and ICA for joint inference of imaging, genetic, and ERP data. Neuroimage 2009; 45(1 Suppl): S163-72.
-
(2009)
Neuroimage
, vol.45
, Issue.1 SUPPL.
-
-
Calhoun, V.D.1
Liu, J.2
Adali, T.3
-
341
-
-
78650630759
-
Individual prediction of cognitive decline in mild cognitive impairment using support vector machine-based analysis of diffusion tensor imaging data
-
Haller S, Nguyen D, Rodriguez C, et al. Individual prediction of cognitive decline in mild cognitive impairment using support vector machine-based analysis of diffusion tensor imaging data. J Alzheimers Dis 2010; 22: 315-27.
-
(2010)
J Alzheimers Dis
, vol.22
, pp. 315-327
-
-
Haller, S.1
Nguyen, D.2
Rodriguez, C.3
-
342
-
-
58549083944
-
Support vector machine-based classification of Alzheimer's disease from whole-brain anatomical MRI
-
Magnin B, Mesrob L, Kinkingnehun S, et al. Support vector machine-based classification of Alzheimer's disease from whole-brain anatomical MRI. Neuroradiology 2009; 51: 73-83.
-
(2009)
Neuroradiology
, vol.51
, pp. 73-83
-
-
Magnin, B.1
Mesrob, L.2
Kinkingnehun, S.3
-
343
-
-
80052364811
-
Computer aided diagnosis system for alzheimer disease using brain diffusion tensor imaging features selected by Pearson's correlation
-
Grana M, Termenon M, Savio A, et al. Computer aided diagnosis system for alzheimer disease using brain diffusion tensor imaging features selected by Pearson's correlation. Neurosci Lett 2011; 502: 225-9.
-
(2011)
Neurosci Lett
, vol.502
, pp. 225-229
-
-
Grana, M.1
Termenon, M.2
Savio, A.3
-
344
-
-
84857000430
-
Using Support Vector Machine to identify imaging biomarkers of neurological and psychiatric disease: A critical review
-
Orru G, Pettersson-Yeo W, Marquand AF, Sartori G, Mechelli A. Using Support Vector Machine to identify imaging biomarkers of neurological and psychiatric disease: a critical review. Neurosci Biobehav Rev 2012; 36: 1140-52.
-
(2012)
Neurosci Biobehav Rev
, vol.36
, pp. 1140-1152
-
-
Orru, G.1
Pettersson-Yeo, W.2
Marquand, A.F.3
Sartori, G.4
Mechelli, A.5
-
345
-
-
38749113910
-
Spatial patterns of brain atrophy in MCI patients, identified via high-dimensional pattern classification, predict subsequent cognitive decline
-
Fan Y, Batmanghelich N, Clark CM, Davatzikos C. Spatial patterns of brain atrophy in MCI patients, identified via high-dimensional pattern classification, predict subsequent cognitive decline. Neuroimage 2008; 39: 1731-43.
-
(2008)
Neuroimage
, vol.39
, pp. 1731-1743
-
-
Fan, Y.1
Batmanghelich, N.2
Clark, C.M.3
Davatzikos, C.4
-
346
-
-
79551576499
-
Predictive markers for AD in a multi-modality framework: An analysis of MCI progression in the ADNI population
-
Hinrichs C, Singh V, Xu G, Johnson SC. Predictive markers for AD in a multi-modality framework: an analysis of MCI progression in the ADNI population. Neuroimage 2011; 55: 574-89.
-
(2011)
Neuroimage
, vol.55
, pp. 574-589
-
-
Hinrichs, C.1
Singh, V.2
Xu, G.3
Johnson, S.C.4
-
347
-
-
79952073234
-
Multimodal classification of Alzheimer's disease and mild cognitive impairment
-
Zhang D, Wang Y, Zhou L, Yuan H, Shen D. Multimodal classification of Alzheimer's disease and mild cognitive impairment. Neuroimage 2011; 55: 856-67.
-
(2011)
Neuroimage
, vol.55
, pp. 856-867
-
-
Zhang, D.1
Wang, Y.2
Zhou, L.3
Yuan, H.4
Shen, D.5
-
348
-
-
38749113910
-
Spatial patterns of brain atrophy in MCI patients, identified via high-dimensional pattern classification, predict subsequent cognitive decline
-
Fan Y, Batmanghelich N, Clark CM, Davatzikos C. Spatial patterns of brain atrophy in MCI patients, identified via high-dimensional pattern classification, predict subsequent cognitive decline. Neuroimage 2008; 39: 1731-43.
-
(2008)
Neuroimage
, vol.39
, pp. 1731-1743
-
-
Fan, Y.1
Batmanghelich, N.2
Clark, C.M.3
Davatzikos, C.4
-
349
-
-
77949654006
-
Characterization of atrophic changes in the cerebral cortex using fractal dimensional analysis
-
King RD, George AT, Jeon T, et al. Characterization of atrophic changes in the cerebral cortex using fractal dimensional analysis. Brain Imaging Behav 2009; 3: 154-66.
-
(2009)
Brain Imaging Behav
, vol.3
, pp. 154-166
-
-
King, R.D.1
George, A.T.2
Jeon, T.3
-
350
-
-
77956060131
-
Fractal dimension analysis of the cortical ribbon in mild Alzheimer's disease
-
King RD, Brown B, Hwang M, Jeon T, George AT. Fractal dimension analysis of the cortical ribbon in mild Alzheimer's disease. Neuroimage 2010; 53: 471-9.
-
(2010)
Neuroimage
, vol.53
, pp. 471-479
-
-
King, R.D.1
Brown, B.2
Hwang, M.3
Jeon, T.4
George, A.T.5
-
351
-
-
33747773681
-
Multifractal analysis of deep white matter microstructural changes on MRI in relation to early-stage atherosclerosis
-
Takahashi T, Murata T, Narita K, et al. Multifractal analysis of deep white matter microstructural changes on MRI in relation to early-stage atherosclerosis. Neuroimage 2006; 32: 1158-66.
-
(2006)
Neuroimage
, vol.32
, pp. 1158-1166
-
-
Takahashi, T.1
Murata, T.2
Narita, K.3
-
352
-
-
4744364012
-
Quantitative evaluation of age-related white matter microstructural changes on MRI by multifractal analysis
-
Takahashi T, Murata T, Omori M, et al. Quantitative evaluation of age-related white matter microstructural changes on MRI by multifractal analysis. J Neurol Sci 2004; 225: 33-7.
-
(2004)
J Neurol Sci
, vol.225
, pp. 33-37
-
-
Takahashi, T.1
Murata, T.2
Omori, M.3
-
353
-
-
0038823525
-
The endophenotype concept in psychiatry: Etymology and strategic intentions
-
Gottesman II, Gould TD. The endophenotype concept in psychiatry: etymology and strategic intentions. Am J Psychiatry 2003; 160: 636-45.
-
(2003)
Am J Psychiatry
, vol.160
, pp. 636-645
-
-
Gottesman, I.I.1
Gould, T.D.2
-
354
-
-
65249132270
-
Rapid neocortical dynamics: Cellular and network mechanisms
-
Haider B, McCormick DA. Rapid neocortical dynamics: cellular and network mechanisms. Neuron 2009; 62: 171-89.
-
(2009)
Neuron
, vol.62
, pp. 171-189
-
-
Haider, B.1
McCormick, D.A.2
-
356
-
-
78149422984
-
From maps to mechanisms through neuroimaging of schizophrenia
-
Meyer-Lindenberg A. From maps to mechanisms through neuroimaging of schizophrenia. Nature 2010; 468: 194-202.
-
(2010)
Nature
, vol.468
, pp. 194-202
-
-
Meyer-Lindenberg, A.1
-
358
-
-
77956213924
-
Imaging genetics: Progressing by leaps and bounds
-
Pezawas L, Meyer-Lindenberg A. Imaging genetics: progressing by leaps and bounds. Neuroimage 2010; 53: 801-3.
-
(2010)
Neuroimage
, vol.53
, pp. 801-803
-
-
Pezawas, L.1
Meyer-Lindenberg, A.2
-
359
-
-
77954625486
-
Imaging genetics-days of future past
-
Bigos KL, Weinberger DR. Imaging genetics-days of future past. Neuroimage 2010; 53: 804-9.
-
(2010)
Neuroimage
, vol.53
, pp. 804-809
-
-
Bigos, K.L.1
Weinberger, D.R.2
-
361
-
-
84860284612
-
Brain connectivity in psychiatric imaging genetics
-
Tost H, Bilek E, Meyer-Lindenberg A. Brain connectivity in psychiatric imaging genetics. Neuroimage 2012; 62(4): 2250-60.
-
(2012)
Neuroimage
, vol.62
, Issue.4
, pp. 2250-2260
-
-
Tost, H.1
Bilek, E.2
Meyer-Lindenberg, A.3
-
362
-
-
67249117049
-
Potential etiologic and functional implications of genome-wide association loci for human diseases and traits
-
Hindorff LA, Sethupathy P, Junkins HA, et al. Potential etiologic and functional implications of genome-wide association loci for human diseases and traits. Proc Natl Acad Sci USA 2009; 106: 9362-67.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 9362-9367
-
-
Hindorff, L.A.1
Sethupathy, P.2
Junkins, H.A.3
-
363
-
-
40949127393
-
How to interpret a genome-wide association study
-
Pearson TA, Manolio TA. How to interpret a genome-wide association study. JAMA 2008; 299: 1335-44.
-
(2008)
JAMA
, vol.299
, pp. 1335-1344
-
-
Pearson, T.A.1
Manolio, T.A.2
-
364
-
-
74949122483
-
A new role for endophenotypes in the GWAS era: Functional characterization of risk variants
-
Hall MH, Smoller JW. A new role for endophenotypes in the GWAS era: functional characterization of risk variants. Harv Rev Psychiatry 2010; 18: 67-74.
-
(2010)
Harv Rev Psychiatry
, vol.18
, pp. 67-74
-
-
Hall, M.H.1
Smoller, J.W.2
-
365
-
-
77952104240
-
Genome-wide analysis reveals novel genes influencing temporal lobe structure with relevance to neurodegeneration in Alzheimer's disease
-
Stein JL, Hua X, Morra JH, et al. Genome-wide analysis reveals novel genes influencing temporal lobe structure with relevance to neurodegeneration in Alzheimer's disease. Neuroimage 2010; 51: 542-54.
-
(2010)
Neuroimage
, vol.51
, pp. 542-554
-
-
Stein, J.L.1
Hua, X.2
Morra, J.H.3
-
366
-
-
58149345887
-
Practical aspects of imputation-driven meta-analysis of genome-wide association studies
-
de Bakker PI, Ferreira MA, Jia X, Neale BM, Raychaudhuri S, Voight BF. Practical aspects of imputation-driven meta-analysis of genome-wide association studies. Hum Mol Genet 2008; 17: R122-8.
-
(2008)
Hum Mol Genet
, vol.17
-
-
de Bakker, P.I.1
Ferreira, M.A.2
Jia, X.3
Neale, B.M.4
Raychaudhuri, S.5
Voight, B.F.6
-
367
-
-
42349112088
-
Genome-wide association studies for complex traits: Consensus, uncertainty and challenges
-
McCarthy MI, Abecasis GR, Cardon LR. Genome-wide association studies for complex traits: consensus, uncertainty and challenges. Nat Rev Genet 2008; 9: 356-69.
-
(2008)
Nat Rev Genet
, vol.9
, pp. 356-369
-
-
McCarthy, M.I.1
Abecasis, G.R.2
Cardon, L.R.3
-
368
-
-
65249183403
-
Meta-analysis in genome-wide association studies
-
Zeggini E, Ioannidis JP. Meta-analysis in genome-wide association studies. Pharmacogenomics 2009; 10: 191-201.
-
(2009)
Pharmacogenomics
, vol.10
, pp. 191-201
-
-
Zeggini, E.1
Ioannidis, J.P.2
-
370
-
-
77954724831
-
Advances and perspectives from genetic research: Development of biological markers in Alzheimer's disease
-
Zetzsche T, Rujescu D, Hardy J, Hampel H. Advances and perspectives from genetic research: development of biological markers in Alzheimer's disease. Expert Rev Mol Diagn 2010; 10: 667-90.
-
(2010)
Expert Rev Mol Diagn
, vol.10
, pp. 667-690
-
-
Zetzsche, T.1
Rujescu, D.2
Hardy, J.3
Hampel, H.4
-
371
-
-
77953625064
-
Genetic variation and neuroimaging measures in Alzheimer disease
-
Biffi A, Anderson CD, Desikan RS. Genetic variation and neuroimaging measures in Alzheimer disease. Arch Neurol 2010; 67: 677-85.
-
(2010)
Arch Neurol
, vol.67
, pp. 677-685
-
-
Biffi, A.1
Anderson, C.D.2
Desikan, R.S.3
-
372
-
-
79958226299
-
Clinical practice. Mild cognitive impairment
-
Petersen RC. Clinical practice. Mild cognitive impairment. N Engl J Med 2011; 364: 2227-34.
-
(2011)
N Engl J Med
, vol.364
, pp. 2227-2234
-
-
Petersen, R.C.1
-
373
-
-
77954021537
-
Alzheimer's Disease Neuroimaging Initiative biomarkers as quantitative phenotypes: Genetics core aims, progress, and plans
-
Saykin AJ, Shen L, Foroud TM, et al. Alzheimer's Disease Neuroimaging Initiative biomarkers as quantitative phenotypes: Genetics core aims, progress, and plans. Alzheimers Dement 2010; 6: 265-73.
-
(2010)
Alzheimers Dement
, vol.6
, pp. 265-273
-
-
Saykin, A.J.1
Shen, L.2
Foroud, T.M.3
-
374
-
-
77149159754
-
Cortical binding of Pittsburgh compound B, an endophenotype for genetic studies of Alzheimer's disease
-
Hinrichs AL, Mintun MA, Head D. Cortical binding of Pittsburgh compound B, an endophenotype for genetic studies of Alzheimer's disease. Biol Psychiatry 2010; 67: 581-3.
-
(2010)
Biol Psychiatry
, vol.67
, pp. 581-583
-
-
Hinrichs, A.L.1
Mintun, M.A.2
Head, D.3
-
375
-
-
73549092137
-
Pittsburgh compound B imaging and prediction of progression from cognitive normality to symptomatic Alzheimer disease
-
Morris JC, Roe CM, Grant E, et al. Pittsburgh compound B imaging and prediction of progression from cognitive normality to symptomatic Alzheimer disease. Arch Neurol 2009; 66: 1469-75.
-
(2009)
Arch Neurol
, vol.66
, pp. 1469-1475
-
-
Morris, J.C.1
Roe, C.M.2
Grant, E.3
-
376
-
-
77954680712
-
A diffusion tensor MRI study of patients with MCI and AD with a 2-year clinical follow-up
-
Scola E, Bozzali M, Agosta F. A diffusion tensor MRI study of patients with MCI and AD with a 2-year clinical follow-up. J Neurol Neurosurg Psychiatry 2010; 81: 798-805.
-
(2010)
J Neurol Neurosurg Psychiatry
, vol.81
, pp. 798-805
-
-
Scola, E.1
Bozzali, M.2
Agosta, F.3
-
378
-
-
84876107858
-
Epigenetic down regulation of nerve growth factor during alcohol withdrawal
-
Heberlein A, Muschler M, Frieling H, et al. Epigenetic down regulation of nerve growth factor during alcohol withdrawal. Addict Biol 2013; 18(3): 508-10.
-
(2013)
Addict Biol
, vol.18
, Issue.3
, pp. 508-510
-
-
Heberlein, A.1
Muschler, M.2
Frieling, H.3
-
379
-
-
77957353569
-
A longitudinal study of epigenetic variation in twins
-
Wong CC, Caspi A, Williams B, et al. A longitudinal study of epigenetic variation in twins. Epigenetics 2010; 5: 516-26.
-
(2010)
Epigenetics
, vol.5
, pp. 516-526
-
-
Wong, C.C.1
Caspi, A.2
Williams, B.3
-
380
-
-
79955782889
-
Stress-related methylation of the catechol-O-methyltransferase Val 158 allele predicts human prefrontal cognition and activity
-
Ursini G, Bollati V, Fazio L, et al. Stress-related methylation of the catechol-O-methyltransferase Val 158 allele predicts human prefrontal cognition and activity. J Neurosci 2011; 31: 6692-8.
-
(2011)
J Neurosci
, vol.31
, pp. 6692-6698
-
-
Ursini, G.1
Bollati, V.2
Fazio, L.3
-
381
-
-
49249103817
-
Molecular mechanisms of stress-induced prefrontal cortical impairment: Implications for mental illness
-
Hains AB, Arnsten AF. Molecular mechanisms of stress-induced prefrontal cortical impairment: implications for mental illness. Learn Mem 2008; 15: 551-64.
-
(2008)
Learn Mem
, vol.15
, pp. 551-564
-
-
Hains, A.B.1
Arnsten, A.F.2
-
382
-
-
77953104962
-
Distribution of catechol-O-methyltransferase (COMT) proteins and enzymatic activities in wild-type and soluble COMT deficient mice
-
Myöhänen TT, Schendzielorz N, Männistö PT. Distribution of catechol-O-methyltransferase (COMT) proteins and enzymatic activities in wild-type and soluble COMT deficient mice. J Neurochem 2010; 113: 1632-43.
-
(2010)
J Neurochem
, vol.113
, pp. 1632-1643
-
-
Myöhänen, T.T.1
Schendzielorz, N.2
Männistö, P.T.3
-
383
-
-
0035810850
-
Effect of COMT Val108/158 Met genotype on frontal lobe function and risk for schizophrenia
-
Egan MF, Goldberg TE, Kolachana BS, et al. Effect of COMT Val108/158 Met genotype on frontal lobe function and risk for schizophrenia. Proc Natl Acad Sci USA 2001; 98: 6917-22.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 6917-6922
-
-
Egan, M.F.1
Goldberg, T.E.2
Kolachana, B.S.3
-
384
-
-
6344265879
-
Functional analysis of genetic variation in catechol-Omethyltransferase (COMT): Effects on mRNA, protein, and enzyme activity in postmortem human brain
-
Chen J, Lipska BK, Halim N, et al. Functional analysis of genetic variation in catechol-Omethyltransferase (COMT): effects on mRNA, protein, and enzyme activity in postmortem human brain. Am J Hum Genet 2004; 75: 807-21.
-
(2004)
Am J Hum Genet
, vol.75
, pp. 807-821
-
-
Chen, J.1
Lipska, B.K.2
Halim, N.3
-
385
-
-
52049116298
-
Genetic dissection of the role of catechol-O-methyltransferase in cognition and stress reactivity in mice
-
Papaleo F, Crawley JN, Song J, et al. Genetic dissection of the role of catechol-O-methyltransferase in cognition and stress reactivity in mice. J Neurosci 2008; 28: 8709-23.
-
(2008)
J Neurosci
, vol.28
, pp. 8709-8723
-
-
Papaleo, F.1
Crawley, J.N.2
Song, J.3
-
386
-
-
84862859049
-
Methylation and the human brain: Towards a new discipline of imaging epigenetics
-
Wiers CE. Methylation and the human brain: towards a new discipline of imaging epigenetics Eur Arch Psychiatry Clin Neurosci 2012; 262: 271-3.
-
(2012)
Eur Arch Psychiatry Clin Neurosci
, vol.262
, pp. 271-273
-
-
Wiers, C.E.1
-
387
-
-
37349066507
-
Imaging genetics of brain longevity and mental wellness: The next frontier?
-
Petrella JR, Mattay VS, Doraiswamy PM. Imaging genetics of brain longevity and mental wellness: the next frontier? Radiology 2008; 246: 20-32.
-
(2008)
Radiology
, vol.246
, pp. 20-32
-
-
Petrella, J.R.1
Mattay, V.S.2
Doraiswamy, P.M.3
-
388
-
-
77951854270
-
Genetic sensitivity to the environment: The case of the serotonin transporter gene and its implications for studying complex diseases and traits
-
Caspi A, Hariri AR, Holmes A, Uher R, Moffitt TE. Genetic sensitivity to the environment: the case of the serotonin transporter gene and its implications for studying complex diseases and traits. Am J Psychiatry 2010; 167: 509-27.
-
(2010)
Am J Psychiatry
, vol.167
, pp. 509-527
-
-
Caspi, A.1
Hariri, A.R.2
Holmes, A.3
Uher, R.4
Moffitt, T.E.5
-
389
-
-
67651033618
-
The neurobiology of individual differences in complex behavioral traits
-
Hariri AR. The neurobiology of individual differences in complex behavioral traits. Annu Rev Neurosci 2009; 32: 225-47.
-
(2009)
Annu Rev Neurosci
, vol.32
, pp. 225-247
-
-
Hariri, A.R.1
-
390
-
-
80051952765
-
Understanding risk for psychopathology through imaging gene-environment interactions
-
Hyde LW, Bogdan R, Hariri AR. Understanding risk for psychopathology through imaging gene-environment interactions. Trends Cogn Sci 2011; 15: 417-27.
-
(2011)
Trends Cogn Sci
, vol.15
, pp. 417-427
-
-
Hyde, L.W.1
Bogdan, R.2
Hariri, A.R.3
-
392
-
-
76749090671
-
Epigenetics and the biological definition of gene x environment interactions
-
Meaney MJ. Epigenetics and the biological definition of gene x environment interactions. Child Dev 2010; 81: 41-79.
-
(2010)
Child Dev
, vol.81
, pp. 41-79
-
-
Meaney, M.J.1
-
393
-
-
79958766982
-
Toward an integrated genetic and epigenetic approach to Alzheimer's disease
-
Mill J. Toward an integrated genetic and epigenetic approach to Alzheimer's disease. Neurobiol Aging 2011; 32: 1188-91.
-
(2011)
Neurobiol Aging
, vol.32
, pp. 1188-1191
-
-
Mill, J.1
-
394
-
-
78650429158
-
Epigenetic studies of psychosis: Current findings, methodological approaches, and implications for postmortem research
-
Pidsley R., Mill J. Epigenetic studies of psychosis: current findings, methodological approaches, and implications for postmortem research. Biol Psychiatry 2011; 69: 146-56.
-
(2011)
Biol Psychiatry
, vol.69
, pp. 146-156
-
-
Pidsley, R.1
Mill, J.2
-
395
-
-
38549122239
-
International genome project launched
-
Check-Hayden E. International genome project launched. Nature 2008; 541: 378-9.
-
(2008)
Nature
, vol.541
, pp. 378-379
-
-
Check-Hayden, E.1
-
396
-
-
38549161042
-
A plan to capture human diversity in 1000 genomes
-
Kaiser J. A plan to capture human diversity in 1000 genomes. Science 2008; 319: 395.
-
(2008)
Science
, vol.319
, pp. 395
-
-
Kaiser, J.1
-
398
-
-
3242663659
-
An integrated epigenetic and genetic approach to common human disease
-
Bjornsson HT, Fallin MD, Feinberg AP. An integrated epigenetic and genetic approach to common human disease. Trends Genet 2004; 20: 350-8.
-
(2004)
Trends Genet
, vol.20
, pp. 350-358
-
-
Bjornsson, H.T.1
Fallin, M.D.2
Feinberg, A.P.3
-
399
-
-
33645737308
-
A single nucleotide polymorphism chip-based method for combined genetic and epigenetic profiling: Validation in decitabine therapy and tumor/normal comparisons
-
Yuan E, Haghighi F, White S, et al. A single nucleotide polymorphism chip-based method for combined genetic and epigenetic profiling: validation in decitabine therapy and tumor/normal comparisons. Cancer Res 2006; 66: 3443-51.
-
(2006)
Cancer Res
, vol.66
, pp. 3443-3451
-
-
Yuan, E.1
Haghighi, F.2
White, S.3
-
401
-
-
34247278900
-
The 2006 Henry N. Wagner Lecture: Of mice and men (and positrons)--advances in PET imaging technology
-
Cherry SR. The 2006 Henry N. Wagner Lecture: Of mice and men (and positrons)--advances in PET imaging technology. J Nucl Med 2006; 47: 1735-45.
-
(2006)
J Nucl Med
, vol.47
, pp. 1735-1745
-
-
Cherry, S.R.1
|