The methylation status of cytosines in a τ gene promoter region alters with age to downregulate transcriptional activity in human cerebral cortex

Neuroscience Letters

Volumn 275, Issue 2, 1999, Pages 89-92

  Tohgi, Hideo ^a   Utsugisawa, Kimiaki ^a   Nagane, Yuriko ^a   Yoshimura, Masahiro ^b   Ukitsu, Miyuki ^a   Genda, Yasuko ^a  

^a IWATE MEDICAL UNIVERSITY   (Japan)

^b Kyoto Municipal University   (Japan)

Author keywords

; Aging; DNA methylation; Neurofibrillary tangle; Promoter

Indexed keywords

TAU PROTEIN;

ADULT; AGED; AGING; ARTICLE; BRAIN CORTEX; CONTROLLED STUDY; DNA METHYLATION; HUMAN; HUMAN CELL; NEUROFIBRILLARY TANGLE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; TRANSCRIPTION REGULATION;

ADULT; AGED; AGED, 80 AND OVER; AGING; AUTOPSY; BASE SEQUENCE; CEREBRAL CORTEX; CYTOSINE; DNA METHYLATION; DOWN-REGULATION; HUMANS; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; POLYMERASE CHAIN REACTION; PROMOTER REGIONS (GENETICS); SEQUENCE ANALYSIS, DNA; TAU PROTEINS; TRANSCRIPTION, GENETIC;

EID: 0032716797     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(99)00731-4     Document Type: Article

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