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Volumn 19, Issue 2, 1998, Pages 187-191

Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; HISTONE DEACETYLASE;

EID: 0031837109     PISSN: 10614036     EISSN: None     Source Type: Journal    
DOI: 10.1038/561     Document Type: Article
Times cited : (2312)

References (30)
  • 1
    • 0025006860 scopus 로고
    • High levels of de novo methylation and altered chromatin structure at CpG islands in cell lines
    • Antequera, F., Boyes, J. & Bird, A. High levels of de novo methylation and altered chromatin structure at CpG islands in cell lines. Cell 62, 503-514 (1990).
    • (1990) Cell , vol.62 , pp. 503-514
    • Antequera, F.1    Boyes, J.2    Bird, A.3
  • 2
    • 0022545498 scopus 로고
    • DNA methylation affects the formation of active chromatin
    • Keshet, I., Lieman-Hurwitz, J. & Cedar, H. DNA methylation affects the formation of active chromatin. Cell 44, 535-543 (1986).
    • (1986) Cell , vol.44 , pp. 535-543
    • Keshet, I.1    Lieman-Hurwitz, J.2    Cedar, H.3
  • 3
    • 0030840954 scopus 로고    scopus 로고
    • Cytosine methylation and the ecology of intragenomic parasites
    • Yoder, J.A., Walsh, C.P. & Bestor, T.H. Cytosine methylation and the ecology of intragenomic parasites. Trends Genet. 13, 335-340 (1997).
    • (1997) Trends Genet. , vol.13 , pp. 335-340
    • Yoder, J.A.1    Walsh, C.P.2    Bestor, T.H.3
  • 4
    • 0028940587 scopus 로고
    • Gene number, noise reduction and biological complexity
    • Bird, A. Gene number, noise reduction and biological complexity. Trends Genet. 11, 94-100 (1995).
    • (1995) Trends Genet. , vol.11 , pp. 94-100
    • Bird, A.1
  • 5
    • 0027378582 scopus 로고
    • Role of DNA methylation in genomic imprinting
    • Li, E., Beard, C. & Jaenisch, R. Role of DNA methylation in genomic imprinting. Nature 366, 362-365 (1993).
    • (1993) Nature , vol.366 , pp. 362-365
    • Li, E.1    Beard, C.2    Jaenisch, R.3
  • 6
    • 0031416750 scopus 로고    scopus 로고
    • Genetic and epigenetic aspects of DNA methylation on genome expression, evolution, mutation and carcinogenesis
    • Zingg, J.M. & Jones, P.A. Genetic and epigenetic aspects of DNA methylation on genome expression, evolution, mutation and carcinogenesis. Carcinogenesis 18, 869-882 (1997).
    • (1997) Carcinogenesis , vol.18 , pp. 869-882
    • Zingg, J.M.1    Jones, P.A.2
  • 7
    • 0030909592 scopus 로고    scopus 로고
    • Altered DNA methylation and genome instability: A new pathway to cancer?
    • Jones, P.A. & Gonzalgo, M.L Altered DNA methylation and genome instability: a new pathway to cancer? Proc. Natl. Acad. Sci. USA 94, 2103-2105 (1997).
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 2103-2105
    • Jones, P.A.1    Gonzalgo, M.L.2
  • 8
    • 0028875205 scopus 로고
    • Methylation of the 5′ CpG island of the p16/CDKN2 tumor suppressor gene in normal and transformed human tissues correlates with gene silencing
    • Gonzalez-Zulueta, M. et al. Methylation of the 5′ CpG island of the p16/CDKN2 tumor suppressor gene in normal and transformed human tissues correlates with gene silencing. Cancer Res. 55, 4531-4535 (1995).
    • (1995) Cancer Res. , vol.55 , pp. 4531-4535
    • Gonzalez-Zulueta, M.1
  • 10
    • 0029011539 scopus 로고
    • 5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers
    • Merlo, A. et al. 5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers. Nature Med. 1, 686-692 (1995).
    • (1995) Nature Med. , vol.1 , pp. 686-692
    • Merlo, A.1
  • 11
    • 0344630574 scopus 로고
    • Chromatin structure is required to block transcription of the methylated herpes simplex virus thymidine kinase gene
    • Buschhausen, G., Wittig, B., Graessmann, M. & Graessman, A. Chromatin structure is required to block transcription of the methylated herpes simplex virus thymidine kinase gene. Proc. Natl. Acad. Sci. USA 84, 1177-1181 (1987).
    • (1987) Proc. Natl. Acad. Sci. USA , vol.84 , pp. 1177-1181
    • Buschhausen, G.1    Wittig, B.2    Graessmann, M.3    Graessman, A.4
  • 12
    • 0031104930 scopus 로고    scopus 로고
    • DNA methylation directs a timedependent repression of transcription initiation
    • Kass, S.U., Landsberger, N. & Wolffe, A.P. DNA methylation directs a timedependent repression of transcription initiation. Curr. Biol. 7, 157-165 (1997).
    • (1997) Curr. Biol. , vol.7 , pp. 157-165
    • Kass, S.U.1    Landsberger, N.2    Wolffe, A.P.3
  • 13
    • 0031003938 scopus 로고    scopus 로고
    • MeCP2 is a transcriptional represser with abundant binding sites in genomic chromatin
    • Nan, X., Campoy, J. & Bird, A. MeCP2 is a transcriptional represser with abundant binding sites in genomic chromatin. Cell 88, 1-11 (1997).
    • (1997) Cell , vol.88 , pp. 1-11
    • Nan, X.1    Campoy, J.2    Bird, A.3
  • 14
    • 0029655782 scopus 로고    scopus 로고
    • DNA methylation specifies chromosomal localization of MeCP2
    • Nan, X. Tate, P., Li, E. & Bird, A.P. DNA methylation specifies chromosomal localization of MeCP2. Mol. Cell. Biol. 16, 414-421 (1996).
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 414-421
    • Nan, X.1    Tate, P.2    Li, E.3    Bird, A.P.4
  • 15
    • 0028905563 scopus 로고
    • Mad-Max transcriptional repression is mediated by ternary complex formation with mammalian homologs of yeast represser Sin3
    • Ayer, D.E., Lawrence, Q.A. & Eisenman, R.N. Mad-Max transcriptional repression is mediated by ternary complex formation with mammalian homologs of yeast represser Sin3. Cell 80, 767-776 (1995).
    • (1995) Cell , vol.80 , pp. 767-776
    • Ayer, D.E.1    Lawrence, Q.A.2    Eisenman, R.N.3
  • 16
    • 0030959244 scopus 로고    scopus 로고
    • Role of NCoR and histone deacetylase in Sin3-mediated transcriptional and oncogenic repression
    • Alland, L. et al. Role of NCoR and histone deacetylase in Sin3-mediated transcriptional and oncogenic repression. Nature 387, 49-55 (1997).
    • (1997) Nature , vol.387 , pp. 49-55
    • Alland, L.1
  • 17
    • 17744413444 scopus 로고    scopus 로고
    • N-CoR, mSIN3, and histone deacetylase in a complex required for repression by nuclear receptors and Mad
    • Heinzel, T. et al. N-CoR, mSIN3, and histone deacetylase in a complex required for repression by nuclear receptors and Mad. Nature 387, 43-48 (1997).
    • (1997) Nature , vol.387 , pp. 43-48
    • Heinzel, T.1
  • 18
    • 0030969516 scopus 로고    scopus 로고
    • Histone deacetylase associated with the mSin3 corepressor mediate Mad transcriptional repression
    • Laherty, CD. et al. Histone deacetylase associated with the mSin3 corepressor mediate Mad transcriptional repression. Cell 89, 349-356 (1997).
    • (1997) Cell , vol.89 , pp. 349-356
    • Laherty, C.D.1
  • 19
    • 0343924289 scopus 로고    scopus 로고
    • Repression by Ume6 involves recruitment of a complex containing Sin3 corepressor and Rpd3 histone deacetylase to target promoters
    • Kadosh, D. & Struhl, K. Repression by Ume6 involves recruitment of a complex containing Sin3 corepressor and Rpd3 histone deacetylase to target promoters. Cell 89, 365-571 (1997).
    • (1997) Cell , vol.89 , pp. 365-571
    • Kadosh, D.1    Struhl, K.2
  • 20
    • 0032518799 scopus 로고    scopus 로고
    • Distinct requirements for chromatin assembly in transcriptional repression by thyroid hormone receptor and histone deacetylase
    • Wong, J., Patterton, D., Imhof, A., Shi, Y.-B. & Wolffe, A.P. Distinct requirements for chromatin assembly in transcriptional repression by thyroid hormone receptor and histone deacetylase. EMBO J. 17, 520-534 (1998).
    • (1998) EMBO J. , vol.17 , pp. 520-534
    • Wong, J.1    Patterton, D.2    Imhof, A.3    Shi, Y.-B.4    Wolffe, A.P.5
  • 21
    • 0027495467 scopus 로고
    • Dissection of the methyl-CpG binding domain from the chromosal protein MeCP2
    • Nan, X., Meehan, R.R. & Bird, A.P. Dissection of the methyl-CpG binding domain from the chromosal protein MeCP2. Nucleic Acids Res. 21, 4886-4892 (1993).
    • (1993) Nucleic Acids Res. , vol.21 , pp. 4886-4892
    • Nan, X.1    Meehan, R.R.2    Bird, A.P.3
  • 22
    • 0028800296 scopus 로고
    • The role of chromatin and Xenopus heat shock transcription factor (XHSF1) in the regulation of the Xenopus hsp70 promoter in vivo
    • Landsberger, N. & Wolffe, A.P. The role of chromatin and Xenopus heat shock transcription factor (XHSF1) in the regulation of the Xenopus hsp70 promoter in vivo. Mol. Cell. Biol. 15, 6013-6024 (1995).
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 6013-6024
    • Landsberger, N.1    Wolffe, A.P.2
  • 23
    • 0030739851 scopus 로고    scopus 로고
    • Remodeling of regulatory nucleoprotein complexes on the Xenopus hsp70 promoter during meiotic maturation of the Xenopus oocyte
    • Landsberger, N. & Wolffe, A.P. Remodeling of regulatory nucleoprotein complexes on the Xenopus hsp70 promoter during meiotic maturation of the Xenopus oocyte. EMBO J. 16, 4361-1373 (1997).
    • (1997) EMBO J. , vol.16 , pp. 4361-11373
    • Landsberger, N.1    Wolffe, A.P.2
  • 24
    • 0028106737 scopus 로고
    • Dependence of transcriptional repression on CpG methylation density
    • Hsieh, C.-L. Dependence of transcriptional repression on CpG methylation density. Mol. Cell. Biol. 14, 5487-5494 (1994).
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 5487-5494
    • Hsieh, C.-L.1
  • 25
    • 0027361810 scopus 로고
    • Inactive chromatin spreads from a focus of methylation
    • Kass, S.U., Goddard, J.P. & Adams, R.L.P. Inactive chromatin spreads from a focus of methylation. Mol. Cell. Biol. 13, 7372-7379 (1993).
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 7372-7379
    • Kass, S.U.1    Goddard, J.P.2    Adams, R.L.P.3
  • 26
    • 0026439115 scopus 로고
    • A targeting sequence directs DNA methyltransferase to sites of DNA replication in mammalian nuclei
    • Leonhardt, H., Page, A.W., Weier, H.-U. & Bester, T.H. A targeting sequence directs DNA methyltransferase to sites of DNA replication in mammalian nuclei. Cell 71, 865-673 (1992).
    • (1992) Cell , vol.71 , pp. 865-1673
    • Leonhardt, H.1    Page, A.W.2    Weier, H.-U.3    Bester, T.H.4
  • 27
    • 0020804287 scopus 로고
    • Methylation of replicating and post replicated mouse L-cell DNA
    • Gruenbaum, Y., Szyf, M., Cedar, H. & Razin, A. Methylation of replicating and post replicated mouse L-cell DNA. Proc. Natl. Acad. Sci. USA 80, 4919-4921 (1983).
    • (1983) Proc. Natl. Acad. Sci. USA , vol.80 , pp. 4919-4921
    • Gruenbaum, Y.1    Szyf, M.2    Cedar, H.3    Razin, A.4
  • 28
    • 0032484897 scopus 로고    scopus 로고
    • The cancer-chromatin connection
    • De Pinho, R. The cancer-chromatin connection. Nature 391, 533-536 (1998).
    • (1998) Nature , vol.391 , pp. 533-536
    • De Pinho, R.1
  • 29
    • 0029744342 scopus 로고
    • Nucleosome assembly on methylated CGG triplet repeats in the Fragile X Mental Retardation gene 1 promoter
    • Godde, J.S., Kass, S.U., Hirst, M.C. & Wolffe, A.P. Nucleosome assembly on methylated CGG triplet repeats in the Fragile X Mental Retardation gene 1 promoter. J. Biol. Chem. 271, 24325-24328 (1990).
    • (1990) J. Biol. Chem. , vol.271 , pp. 24325-24328
    • Godde, J.S.1    Kass, S.U.2    Hirst, M.C.3    Wolffe, A.P.4
  • 30
    • 0031588962 scopus 로고    scopus 로고
    • DNA methylation remodels chromatin structure in vitro
    • Davey, C., Pennings, S. & Allan, J. DNA methylation remodels chromatin structure in vitro. J. Mol. Biol. 267, 276-298 (1997).
    • (1997) J. Mol. Biol. , vol.267 , pp. 276-298
    • Davey, C.1    Pennings, S.2    Allan, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.