Sequence-selective DNA binding drugs mithramycin A and chromomycin A3 are potent inhibitors of neuronal apoptosis induced by oxidative stress and DNA damage in cortical neurons

Annals of Neurology

Volumn 49, Issue 3, 2001, Pages 345-354

  Chatterjee, Sukalyan ^a   Zaman, Khalequz ^b   Ryu, Hoon ^a   Conforto, Adriana ^b   Ratan, Rajiv R ^a,c  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^c HARVARD INSTITUTES OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CAMPTOTHECIN; CHROMOMYCIN A3; CYCLOHEXIMIDE; CYSTEINE; DACTINOMYCIN; DNA; GLUTATHIONE; MITHRAMYCIN; PHOSPHORUS 32; SULFUR 35;

ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; DNA BINDING; DNA DAMAGE; GENE EXPRESSION; NERVE CELL NECROSIS; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN SYNTHESIS INHIBITION; RAT;

ANIMALS; APOPTOSIS; BASE SEQUENCE; BRAIN; CELL CULTURE TECHNIQUES; CHROMOMYCIN A3; DNA DAMAGE; ELECTROPHORESIS; MICROSCOPY, PHASE-CONTRAST; NEURODEGENERATIVE DISEASES; NEURONS; OXIDATIVE STRESS; PLICAMYCIN; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0035089787     PISSN: 03645134     EISSN: None     Source Type: Journal    
DOI: 10.1002/ana.71     Document Type: Article

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