Rapid Neocortical Dynamics: Cellular and Network Mechanisms

Neuron

Volumn 62, Issue 2, 2009, Pages 171-189

  Haider, Bilal ^a   McCormick, David A ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BEHAVIOR; BRAIN NERVE CELL; EXCITATORY POSTSYNAPTIC POTENTIAL; HUMAN; INHIBITORY POSTSYNAPTIC POTENTIAL; NEOCORTEX; NERVE CELL MEMBRANE CONDUCTANCE; NERVE CELL MEMBRANE POTENTIAL; NERVE CELL MEMBRANE STEADY POTENTIAL; NERVE CELL NETWORK; NEUROMODULATION; NONHUMAN; PRIORITY JOURNAL; REVIEW; SENSORIMOTOR INTEGRATION; SLEEP WAKING CYCLE; SYNAPTIC TRANSMISSION; WORKING MEMORY;

ANIMALS; HUMANS; MEMBRANE POTENTIALS; MODELS, NEUROLOGICAL; NEOCORTEX; NERVE NET; NEURONS; NONLINEAR DYNAMICS; SYNAPTIC POTENTIALS;

EID: 65249132270     PISSN: 08966273     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuron.2009.04.008     Document Type: Review

References (248)

1. Abeles M., Bergman H., Gat I., Meilijson I., Seidemann E., Tishby N., and Vaadia E. Cortical activity flips among quasi-stationary states. Proc. Natl. Acad. Sci. USA 92 (1995) 8616-8620
2. Adamantidis A.R., Zhang F., Aravanis A.M., Deisseroth K., and de Lecea L. Neural substrates of awakening probed with optogenetic control of hypocretin neurons. Nature 450 (2007) 420-424
3. Aghajanian G.K. Modeling "psychosis" in vitro by inducing disordered neuronal network activity in cortical brain slices. Psychopharmacology (Berl) (2009) 10.1007/s00213-009-1484-9 in press. Published online February 25, 2009
4. Albright T.D., and Stoner G.R. Contextual influences on visual processing. Annu. Rev. Neurosci. 25 (2002) 339-379
5. Alvarez V.A., and Sabatini B.L. Anatomical and physiological plasticity of dendritic spines. Annu. Rev. Neurosci. 30 (2007) 79-97
6. Anderson J.S., Lampl I., Gillespie D.C., and Ferster D. The contribution of noise to contrast invariance of orientation tuning in cat visual cortex. Science 290 (2000) 1968-1972
7. Ardid S., Wang X.J., and Compte A. An integrated microcircuit model of attentional processing in the neocortex. J. Neurosci. 27 (2007) 8486-8495
8. Arieli A., Sterkin A., Grinvald A., and Aertsen A. Dynamics of ongoing activity: explanation of the large variability in evoked cortical responses. Science 273 (1996) 1868-1871
9. Ayaz A., and Chance F.S. Gain modulation of neuronal responses by subtractive and divisive mechanisms of inhibition. J. Neurophysiol. 101 (2009) 958-968
10. Azouz R. Dynamic spatiotemporal synaptic integration in cortical neurons: neuronal gain, revisited. J. Neurophysiol. 94 (2005) 2785-2796
11. Azouz R., and Gray C.M. Cellular mechanisms contributing to response variability of cortical neurons in vivo. J. Neurosci. 19 (1999) 2209-2223
12. Azouz R., and Gray C.M. Adaptive coincidence detection and dynamic gain control in visual cortical neurons in vivo. Neuron 37 (2003) 513-523
13. Azouz R., and Gray C.M. Stimulus-selective spiking is driven by the relative timing of synchronous excitation and disinhibition in cat striate neurons in vivo. Eur. J. Neurosci. 28 (2008) 1286-1300
14. Azouz R., Gray C.M., Nowak L.G., and McCormick D.A. Physiological properties of inhibitory interneurons in cat striate cortex. Cereb. Cortex 7 (1997) 534-545
15. Barraclough D.J., Conroy M.L., and Lee D. Prefrontal cortex and decision making in a mixed-strategy game. Nat. Neurosci. 7 (2004) 404-410
16. Bean B.P. The action potential in mammalian central neurons. Nat. Rev. Neurosci. 8 (2007) 451-465
17. Beloozerova I.N., Sirota M.G., and Swadlow H.A. Activity of different classes of neurons of the motor cortex during locomotion. J. Neurosci. 23 (2003) 1087-1097
18. Bernander O., Douglas R.J., Martin K.A., and Koch C. Synaptic background activity influences spatiotemporal integration in single pyramidal cells. Proc. Natl. Acad. Sci. USA 88 (1991) 11569-11573
19. Bezdudnaya T., Cano M., Bereshpolova Y., Stoelzel C.R., Alonso J.M., and Swadlow H.A. Thalamic burst mode and inattention in the awake LGNd. Neuron 49 (2006) 421-432
20. Binzegger T., Douglas R.J., and Martin K.A. A quantitative map of the circuit of cat primary visual cortex. J. Neurosci. 24 (2004) 8441-8453
21. Blackwell K.T., Czubayko U., and Plenz D. Quantitative estimate of synaptic inputs to striatal neurons during up and down states in vitro. J. Neurosci. 23 (2003) 9123-9132
22. Borg-Graham L.J., Monier C., and Fregnac Y. Visual input evokes transient and strong shunting inhibition in visual cortical neurons. Nature 393 (1998) 369-373
23. Boyden E.S., Zhang F., Bamberg E., Nagel G., and Deisseroth K. Millisecond-timescale, genetically targeted optical control of neural activity. Nat. Neurosci. 8 (2005) 1263-1268
24. Brecht M., Fee M.S., Garaschuk O., Helmchen F., Margrie T.W., Svoboda K., and Osten P. Novel approaches to monitor and manipulate single neurons in vivo. J. Neurosci. 24 (2004) 9223-9227
25. Brecht M., Schneider M., Sakmann B., and Margrie T.W. Whisker movements evoked by stimulation of single pyramidal cells in rat motor cortex. Nature 427 (2004) 704-710
26. Buzsaki G. Large-scale recording of neuronal ensembles. Nat. Neurosci. 7 (2004) 446-451
27. Buzsaki G., and Chrobak J.J. Temporal structure in spatially organized neuronal ensembles: a role for interneuronal networks. Curr. Opin. Neurobiol. 5 (1995) 504-510
28. Buzsaki G., and Draguhn A. Neuronal oscillations in cortical networks. Science 304 (2004) 1926-1929
29. Canolty R.T., Edwards E., Dalal S.S., Soltani M., Nagarajan S.S., Kirsch H.E., Berger M.S., Barbaro N.M., and Knight R.T. High gamma power is phase-locked to theta oscillations in human neocortex. Science 313 (2006) 1626-1628
30. Caporale N., and Dan Y. Spike timing-dependent plasticity: a Hebbian learning rule. Annu. Rev. Neurosci. 31 (2008) 25-46
31. Carandini M., and Ferster D. Membrane potential and firing rate in cat primary visual cortex. J. Neurosci. 20 (2000) 470-484
32. Cardin J.A., Palmer L.A., and Contreras D. Stimulus feature selectivity in excitatory and inhibitory neurons in primary visual cortex. J. Neurosci. 27 (2007) 10333-10344
33. Cardin J.A., Palmer L.A., and Contreras D. Cellular mechanisms underlying stimulus-dependent gain modulation in primary visual cortex neurons in vivo. Neuron 59 (2008) 150-160
34. Cardin J.A., Carlen M., Meletis K., Knoblich U., Zhang F., Deisseroth K., Tsai L.-H., and Moore C.I. Activation of fast spiking interneurons induces gamma oscillations and shapes sensory transmission. Nature (2009) in press
35. Chance F.S., Abbott L.F., and Reyes A.D. Gain modulation from background synaptic input. Neuron 35 (2002) 773-782
36. Chen D., and Fetz E.E. Characteristic membrane potential trajectories in primate sensorimotor cortex neurons recorded in vivo. J. Neurophysiol. 94 (2005) 2713-2725
37. Churchland M.M., Afshar A., and Shenoy K.V. A central source of movement variability. Neuron 52 (2006) 1085-1096
38. Churchland M.M., Yu B.M., Ryu S.I., Santhanam G., and Shenoy K.V. Neural variability in premotor cortex provides a signature of motor preparation. J. Neurosci. 26 (2006) 3697-3712
39. Cohen M.R., and Newsome W.T. Context-dependent changes in functional circuitry in visual area MT. Neuron 60 (2008) 162-173
40. Compte A., Constantinidis C., Tegner J., Raghavachari S., Chafee M.V., Goldman-Rakic P.S., and Wang X.J. Temporally irregular mnemonic persistent activity in prefrontal neurons of monkeys during a delayed response task. J. Neurophysiol. 90 (2003) 3441-3454
41. Compte A., Sanchez-Vives M.V., McCormick D.A., and Wang X.J. Cellular and network mechanisms of slow oscillatory activity (<1 Hz) and wave propagations in a cortical network model. J. Neurophysiol. 89 (2003) 2707-2725
42. Connors B.W., and Gutnick M.J. Intrinsic firing patterns of diverse neocortical neurons. Trends Neurosci. 13 (1990) 99-104
43. Connors B.W., and Long M.A. Electrical synapses in the mammalian brain. Annu. Rev. Neurosci. 27 (2004) 393-418
44. Contreras D., and Steriade M. Cellular basis of EEG slow rhythms: a study of dynamic corticothalamic relationships. J. Neurosci. 15 (1995) 604-622
45. Contreras D., and Palmer L. Response to contrast of electrophysiologically defined cell classes in primary visual cortex. J. Neurosci. 23 (2003) 6936-6945
46. Cossart R., Aronov D., and Yuste R. Attractor dynamics of network UP states in the neocortex. Nature 423 (2003) 283-288
47. Cowan R.L., and Wilson C.J. Spontaneous firing patterns and axonal projections of single corticostriatal neurons in the rat medial agranular cortex. J. Neurophysiol. 71 (1994) 17-32
48. Crochet S., and Petersen C.C. Correlating whisker behavior with membrane potential in barrel cortex of awake mice. Nat. Neurosci. 9 (2006) 608-610
49. Crochet S., Chauvette S., Boucetta S., and Timofeev I. Modulation of synaptic transmission in neocortex by network activities. Eur. J. Neurosci. 21 (2005) 1030-1044
50. Cruikshank S.J., Lewis T.J., and Connors B.W. Synaptic basis for intense thalamocortical activation of feedforward inhibitory cells in neocortex. Nat. Neurosci. 10 (2007) 462-468
51. Csicsvari J., Hirase H., Czurko A., Mamiya A., and Buzsaki G. Oscillatory coupling of hippocampal pyramidal cells and interneurons in the behaving Rat. J. Neurosci. 19 (1999) 274-287
52. Csicsvari J., Jamieson B., Wise K.D., and Buzsaki G. Mechanisms of gamma oscillations in the hippocampus of the behaving rat. Neuron 37 (2003) 311-322
53. Dan Y., and Poo M.M. Spike timing-dependent plasticity: from synapse to perception. Physiol. Rev. 86 (2006) 1033-1048
54. de Kock C.P., Bruno R.M., Spors H., and Sakmann B. Layer- and cell-type-specific suprathreshold stimulus representation in rat primary somatosensory cortex. J. Physiol. 581 (2007) 139-154
55. DeFelipe J., Alonso-Nanclares L., and Arellano J.I. Microstructure of the neocortex: comparative aspects. J. Neurocytol. 31 (2002) 299-316
56. Desimone R., and Duncan J. Neural mechanisms of selective visual attention. Annu. Rev. Neurosci. 18 (1995) 193-222
57. Destexhe A., Contreras D., and Steriade M. Spatiotemporal analysis of local field potentials and unit discharges in cat cerebral cortex during natural wake and sleep states. J. Neurosci. 19 (1999) 4595-4608
58. Destexhe A., Rudolph M., Fellous J.M., and Sejnowski T.J. Fluctuating synaptic conductances recreate in vivo-like activity in neocortical neurons. Neuroscience 107 (2001) 13-24
59. Destexhe A., Rudolph M., and Pare D. The high-conductance state of neocortical neurons in vivo. Nat. Rev. Neurosci. 4 (2003) 739-751
60. Destexhe A., Hughes S.W., Rudolph M., and Crunelli V. Are corticothalamic 'up' states fragments of wakefulness?. Trends Neurosci. 30 (2007) 334-342
61. DeWeese M.R., and Zador A.M. Non-Gaussian membrane potential dynamics imply sparse, synchronous activity in auditory cortex. J. Neurosci. 26 (2006) 12206-12218
62. Disney A.A., Aoki C., and Hawken M.J. Gain modulation by nicotine in macaque v1. Neuron 56 (2007) 701-713
63. Douglas R.J., and Martin K.A. Mapping the matrix: the ways of neocortex. Neuron 56 (2007) 226-238
64. Douglas R.J., and Martin K.A. Recurrent neuronal circuits in the neocortex. Curr. Biol. 17 (2007) R496-R500
65. Douglass A.D., Kraves S., Deisseroth K., Schier A.F., and Engert F. Escape behavior elicited by single, channelrhodopsin-2-evoked spikes in zebrafish somatosensory neurons. Curr. Biol. 18 (2008) 1133-1137
66. El Boustani S., Pospischil M., Rudolph-Lilith M., and Destexhe A. Activated cortical states: experiments, analyses and models. J. Physiol. (Paris) 101 (2007) 99-109
67. Feldmeyer D., Egger V., Lubke J., and Sakmann B. Reliable synaptic connections between pairs of excitatory layer 4 neurones within a single 'barrel' of developing rat somatosensory cortex. J. Physiol. 521 (1999) 169-190
68. Ferezou I., Bolea S., and Petersen C.C. Visualizing the cortical representation of whisker touch: voltage-sensitive dye imaging in freely moving mice. Neuron 50 (2006) 617-629
69. Ferezou I., Haiss F., Gentet L.J., Aronoff R., Weber B., and Petersen C.C. Spatiotemporal dynamics of cortical sensorimotor integration in behaving mice. Neuron 56 (2007) 907-923
70. Fox M.D., Snyder A.Z., Vincent J.L., and Raichle M.E. Intrinsic fluctuations within cortical systems account for intertrial variability in human behavior. Neuron 56 (2007) 171-184
71. Fries P., Reynolds J.H., Rorie A.E., and Desimone R. Modulation of oscillatory neuronal synchronization by selective visual attention. Science 291 (2001) 1560-1563
72. Fries P., Nikolic D., and Singer W. The gamma cycle. Trends Neurosci. 30 (2007) 309-316
73. Fuentealba P., Begum R., Capogna M., Jinno S., Marton L.F., Csicsvari J., Thomson A., Somogyi P., and Klausberger T. Ivy cells: a population of nitric-oxide-producing, slow-spiking GABAergic neurons and their involvement in hippocampal network activity. Neuron 57 (2008) 917-929
74. Fujisawa S., Amarasingham A., Harrison M.T., and Buzsaki G. Behavior-dependent short-term assembly dynamics in the medial prefrontal cortex. Nat. Neurosci. 11 (2008) 823-833
75. Gabernet L., Jadhav S.P., Feldman D.E., Carandini M., and Scanziani M. Somatosensory integration controlled by dynamic thalamocortical feed-forward inhibition. Neuron 48 (2005) 315-327
76. Galarreta M., and Hestrin S. Frequency-dependent synaptic depression and the balance of excitation and inhibition in the neocortex. Nat. Neurosci. 1 (1998) 587-594
77. Garaschuk O., Milos R.I., and Konnerth A. Targeted bulk-loading of fluorescent indicators for two-photon brain imaging in vivo. Nat. Protocols 1 (2006) 380-386
78. Genovesio A., Brasted P.J., Mitz A.R., and Wise S.P. Prefrontal cortex activity related to abstract response strategies. Neuron 47 (2005) 307-320
79. Gil Z., Connors B.W., and Amitai Y. Differential regulation of neocortical synapses by neuromodulators and activity. Neuron 19 (1997) 679-686
80. Gilbert C.D., and Sigman M. Brain states: top-down influences in sensory processing. Neuron 54 (2007) 677-696
81. Gradinaru V., Thompson K.R., Zhang F., Mogri M., Kay K., Schneider M.B., and Deisseroth K. Targeting and readout strategies for fast optical neural control in vitro and in vivo. J. Neurosci. 27 (2007) 14231-14238
82. Greenberg D.S., Houweling A.R., and Kerr J.N. Population imaging of ongoing neuronal activity in the visual cortex of awake rats. Nat. Neurosci. 11 (2008) 749-751
83. Grinvald A., and Hildesheim R. VSDI: a new era in functional imaging of cortical dynamics. Nat. Rev. Neurosci. 5 (2004) 874-885
84. Gur M., Beylin A., and Snodderly D.M. Response variability of neurons in primary visual cortex (V1) of alert monkeys. J. Neurosci. 17 (1997) 2914-2920
85. Hahn T.T., Sakmann B., and Mehta M.R. Differential responses of hippocampal subfields to cortical up-down states. Proc. Natl. Acad. Sci. USA 104 (2007) 5169-5174
86. Hahnloser R.H., Douglas R.J., and Hepp K. Attentional recruitment of inter-areal recurrent networks for selective gain control. Neural Comput. 14 (2002) 1669-1689
87. Haider B., Duque A., Hasenstaub A.R., and McCormick D.A. Neocortical network activity in vivo is generated through a dynamic balance of excitation and inhibition. J. Neurosci. 26 (2006) 4535-4545
88. Haider B., Duque A., Hasenstaub A.R., Yu Y., and McCormick D.A. Enhancement of visual responsiveness by spontaneous local network activity in vivo. J. Neurophysiol. 97 (2007) 4186-4202
89. Harris K.D. Neural signatures of cell assembly organization. Nat. Rev. Neurosci. 6 (2005) 399-407
90. Hasenstaub A., Shu Y., Haider B., Kraushaar U., Duque A., and McCormick D.A. Inhibitory postsynaptic potentials carry synchronized frequency information in active cortical networks. Neuron 47 (2005) 423-435
91. Hasenstaub A., Sachdev R.N., and McCormick D.A. State changes rapidly modulate cortical neuronal responsiveness. J. Neurosci. 27 (2007) 9607-9622
92. Hebb D.O. The Organization of Behavior: A Neuropsychological Theory (1949), Wiley, New York
93. Helmchen F., Imoto K., and Sakmann B. Ca2+ buffering and action potential-evoked Ca2+ signaling in dendrites of pyramidal neurons. Biophys. J. 70 (1996) 1069-1081
94. Henze D.A., and Buzsaki G. Action potential threshold of hippocampal pyramidal cells in vivo is increased by recent spiking activity. Neuroscience 105 (2001) 121-130
95. Higley M.J., and Contreras D. Balanced excitation and inhibition determine spike timing during frequency adaptation. J. Neurosci. 26 (2006) 448-457
96. Hirsch J.A., Martinez L.M., Pillai C., Alonso J.M., Wang Q., and Sommer F.T. Functionally distinct inhibitory neurons at the first stage of visual cortical processing. Nat. Neurosci. 6 (2003) 1300-1308
97. Ho N., and Destexhe A. Synaptic background activity enhances the responsiveness of neocortical pyramidal neurons. J. Neurophysiol. 84 (2000) 1488-1496
98. Holcman D., and Tsodyks M. The emergence of Up and Down states in cortical networks. PLoS Comput. Biol. 2 (2006) e23
99. Holt G.R., and Koch C. Shunting inhibition does not have a divisive effect on firing rates. Neural Comput. 9 (1997) 1001-1013
100. Homma R., Baker B.J., Jin L., Garaschuk O., Konnerth A., Cohen L.B., Bleau C.X., Canepari M., Djurisic M., and Zecevic D. Wide-field and two-photon imaging of brain activity with voltage- and calcium-sensitive dyes. Methods Mol. Biol. 489 (2009) 43-79
101. Houweling A.R., and Brecht M. Behavioural report of single neuron stimulation in somatosensory cortex. Nature 451 (2008) 65-68
102. Huber D., Petreanu L., Ghitani N., Ranade S., Hromadka T., Mainen Z., and Svoboda K. Sparse optical microstimulation in barrel cortex drives learned behaviour in freely moving mice. Nature 451 (2008) 61-64
103. Johnson H.A., and Buonomano D.V. Development and plasticity of spontaneous activity and Up states in cortical organotypic slices. J. Neurosci. 27 (2007) 5915-5925
104. Jones M.S., MacDonald K.D., Choi B., Dudek F.E., and Barth D.S. Intracellular correlates of fast (>200 Hz) electrical oscillations in rat somatosensory cortex. J. Neurophysiol. 84 (2000) 1505-1518
105. Kapfer C., Glickfeld L.L., Atallah B.V., and Scanziani M. Supralinear increase of recurrent inhibition during sparse activity in the somatosensory cortex. Nat. Neurosci. 10 (2007) 743-753
106. Kawaguchi Y. Selective cholinergic modulation of cortical GABAergic cell subtypes. J. Neurophysiol. 78 (1997) 1743-1747
107. Kenet T., Bibitchkov D., Tsodyks M., Grinvald A., and Arieli A. Spontaneously emerging cortical representations of visual attributes. Nature 425 (2003) 954-956
108. Kerchner G.A., and Nicoll R.A. Silent synapses and the emergence of a postsynaptic mechanism for LTP. Nat. Rev. Neurosci. 9 (2008) 813-825
109. Kerr J.N., Greenberg D., and Helmchen F. Imaging input and output of neocortical networks in vivo. Proc. Natl. Acad. Sci. USA 102 (2005) 14063-14068
110. Kerr J.N., de Kock C.P., Greenberg D.S., Bruno R.M., Sakmann B., and Helmchen F. Spatial organization of neuronal population responses in layer 2/3 of rat barrel cortex. J. Neurosci. 27 (2007) 13316-13328
111. Klausberger T., Magill P.J., Marton L.F., Roberts J.D., Cobden P.M., Buzsaki G., and Somogyi P. Brain-state- and cell-type-specific firing of hippocampal interneurons in vivo. Nature 421 (2003) 844-848
112. Kole M.H., Ilschner S.U., Kampa B.M., Williams S.R., Ruben P.C., and Stuart G.J. Action potential generation requires a high sodium channel density in the axon initial segment. Nat. Neurosci. 11 (2008) 178-186
113. Kuhn A., Aertsen A., and Rotter S. Neuronal integration of synaptic input in the fluctuation-driven regime. J. Neurosci. 24 (2004) 2345-2356
114. Lampl I., Reichova I., and Ferster D. Synchronous membrane potential fluctuations in neurons of the cat visual cortex. Neuron 22 (1999) 361-374
115. Larkman A.U. Dendritic morphology of pyramidal neurones of the visual cortex of the rat: III. Spine distributions. J. Comp. Neurol. 306 (1991) 332-343
116. Larkum M.E., Senn W., and Luscher H.R. Top-down dendritic input increases the gain of layer 5 pyramidal neurons. Cereb. Cortex 14 (2004) 1059-1070
117. Le Be J.V., Silberberg G., Wang Y., and Markram H. Morphological, electrophysiological, and synaptic properties of corticocallosal pyramidal cells in the neonatal rat neocortex. Cereb. Cortex 17 (2007) 2204-2213
118. Lee J., and Maunsell J.H. A normalization model of attentional modulation of single unit responses. PLoS ONE 4 (2009) e4651
119. Lee A.K., Manns I.D., Sakmann B., and Brecht M. Whole-cell recordings in freely moving rats. Neuron 51 (2006) 399-407
120. Leger J.F., Stern E.A., Aertsen A., and Heck D. Synaptic integration in rat frontal cortex shaped by network activity. J. Neurophysiol. 93 (2005) 281-293
121. Livingstone M.S., and Hubel D.H. Effects of sleep and arousal on the processing of visual information in the cat. Nature 291 (1981) 554-561
122. Llinas R.R. The intrinsic electrophysiological properties of mammalian neurons: insights into central nervous system function. Science 242 (1988) 1654-1664
123. Logothetis N.K. Single units and conscious vision. Philos. Trans. R. Soc. Lond. B Biol. Sci. 353 (1998) 1801-1818
124. London M., and Hausser M. Dendritic computation. Annu. Rev. Neurosci. 28 (2005) 503-532
125. Lorente de No R. Cerebral Cortex: Architecture, intracortical connections, motor projections. In: Fulton J.F. (Ed). Physiology of the Nervous System (1938), Oxford University Press, New York
126. Luck S.J., Chelazzi L., Hillyard S.A., and Desimone R. Neural mechanisms of spatial selective attention in areas V1, V2, and V4 of macaque visual cortex. J. Neurophysiol. 77 (1997) 24-42
127. Luczak A., Bartho P., Marguet S.L., Buzsaki G., and Harris K.D. Sequential structure of neocortical spontaneous activity in vivo. Proc. Natl. Acad. Sci. USA 104 (2007) 347-352
128. Luna R., Hernandez A., Brody C.D., and Romo R. Neural codes for perceptual discrimination in primary somatosensory cortex. Nat. Neurosci. 8 (2005) 1210-1219
129. Luo L., Callaway E.M., and Svoboda K. Genetic dissection of neural circuits. Neuron 57 (2008) 634-660
130. Magee J.C. Dendritic integration of excitatory synaptic input. Nat. Rev. Neurosci. 1 (2000) 181-190
131. Magee J.C., and Johnston D. Plasticity of dendritic function. Curr. Opin. Neurobiol. 15 (2005) 334-342
132. Mainen Z.F., and Sejnowski T.J. Reliability of spike timing in neocortical neurons. Science 268 (1995) 1503-1506
133. Major G., and Tank D. Persistent neural activity: prevalence and mechanisms. Curr. Opin. Neurobiol. 14 (2004) 675-684
134. Major G., Polsky A., Denk W., Schiller J., and Tank D.W. Spatio-temporally graded NMDA spike/plateau potentials in basal dendrites of neocortical pyramidal neurons. J. Neurophysiol. 99 (2008) 2584-2601
135. Malenka R.C., and Bear M.F. LTP and LTD: an embarrassment of riches. Neuron 44 (2004) 5-21
136. Marino J., Schummers J., Lyon D.C., Schwabe L., Beck O., Wiesing P., Obermayer K., and Sur M. Invariant computations in local cortical networks with balanced excitation and inhibition. Nat. Neurosci. 8 (2005) 194-201
137. Markram H., Lubke J., Frotscher M., Roth A., and Sakmann B. Physiology and anatomy of synaptic connections between thick tufted pyramidal neurones in the developing rat neocortex. J. Physiol. 500 (1997) 409-440
138. Markram H., Toledo-Rodriguez M., Wang Y., Gupta A., Silberberg G., and Wu C. Interneurons of the neocortical inhibitory system. Nat. Rev. Neurosci. 5 (2004) 793-807
139. Martinez-Trujillo J.C., and Treue S. Feature-based attention increases the selectivity of population responses in primate visual cortex. Curr. Biol. 14 (2004) 744-751
140. Maunsell J.H., and Treue S. Feature-based attention in visual cortex. Trends Neurosci. 29 (2006) 317-322
141. McAdams C.J., and Maunsell J.H. Effects of attention on orientation-tuning functions of single neurons in macaque cortical area V4. J. Neurosci. 19 (1999) 431-441
142. McAdams C.J., and Reid R.C. Attention modulates the responses of simple cells in monkey primary visual cortex. J. Neurosci. 25 (2005) 11023-11033
143. McCormick D.A. Neurotransmitter actions in the thalamus and cerebral cortex and their role in neuromodulation of thalamocortical activity. Prog. Neurobiol. 39 (1992) 337-388
144. McCormick D.A., and Contreras D. On the cellular and network bases of epileptic seizures. Annu. Rev. Physiol. 63 (2001) 815-846
145. McCormick D.A., Connors B.W., Lighthall J.W., and Prince D.A. Comparative electrophysiology of pyramidal and sparsely spiny stellate neurons of the neocortex. J. Neurophysiol. 54 (1985) 782-806
146. McCormick D.A., Shu Y., and Yu Y. Neurophysiology: Hodgkin and Huxley model-still standing?. Nature 445 (2007) E1-E2
147. McGuire B.A., Gilbert C.D., Rivlin P.K., and Wiesel T.N. Targets of horizontal connections in macaque primary visual cortex. J. Comp. Neurol. 305 (1991) 370-392
148. Metherate R., and Ashe J.H. Ionic flux contributions to neocortical slow waves and nucleus basalis-mediated activation: whole-cell recordings in vivo. J. Neurosci. 13 (1993) 5312-5323
149. Miller E.K., and Cohen J.D. An integrative theory of prefrontal cortex function. Annu. Rev. Neurosci. 24 (2001) 167-202
150. Miller K.D., and Troyer T.W. Neural noise can explain expansive, power-law nonlinearities in neural response functions. J. Neurophysiol. 87 (2002) 653-659
151. Milojkovic B.A., Radojicic M.S., and Antic S.D. A strict correlation between dendritic and somatic plateau depolarizations in the rat prefrontal cortex pyramidal neurons. J. Neurosci. 25 (2005) 3940-3951
152. Mitchell J.F., Sundberg K.A., and Reynolds J.H. Differential attention-dependent response modulation across cell classes in macaque visual area V4. Neuron 55 (2007) 131-141
153. Miura K., Tsubo Y., Okada M., and Fukai T. Balanced excitatory and inhibitory inputs to cortical neurons decouple firing irregularity from rate modulations. J. Neurosci. 27 (2007) 13802-13812
154. Murayama M., Perez-Garci E., Nevian T., Bock T., Senn W., and Larkum M.E. Dendritic encoding of sensory stimuli controlled by deep cortical interneurons. Nature 457 (2009) 1137-1141
155. Murphy B.K., and Miller K.D. Multiplicative gain changes are induced by excitation or inhibition alone. J. Neurosci. 23 (2003) 10040-10051
156. Murphy B.K., and Miller K.D. Balanced amplification: a new mechanism of selective amplification of neural activity patterns. Neuron 61 (2009) 635-648
157. Nagel G., Szellas T., Huhn W., Kateriya S., Adeishvili N., Berthold P., Olliq D., Hegemann P., and Bamberg E. Channelrhodopsin-2, a directly light-gated cation-selective membrane channel. Proc. Natl. Acad. Sci. USA 100 (2003) 13940-13945
158. Narayanan N.S., and Laubach M. Top-down control of motor cortex ensembles by dorsomedial prefrontal cortex. Neuron 52 (2006) 921-931
159. Neher E., and Sakmann B. Single-channel currents recorded from membrane of denervated frog muscle fibres. Nature 260 (1976) 799-802
160. Nelson S.B., Sugino K., and Hempel C.M. The problem of neuronal cell types: a physiological genomics approach. Trends Neurosci. 29 (2006) 339-345
161. Nevian T., Larkum M.E., Polsky A., and Schiller J. Properties of basal dendrites of layer 5 pyramidal neurons: a direct patch-clamp recording study. Nat. Neurosci. 10 (2007) 206-214
162. Nowak L.G., Sanchez-Vives M.V., and McCormick D.A. Influence of low and high frequency inputs on spike timing in visual cortical neurons. Cereb. Cortex 7 (1997) 487-501
163. Nowak L.G., Azouz R., Sanchez-Vives M.V., Gray C.M., and McCormick D.A. Electrophysiological classes of cat primary visual cortical neurons in vivo as revealed by quantitative analyses. J. Neurophysiol. 89 (2003) 1541-1566
164. Nowak L.G., Sanchez-Vives M.V., and McCormick D.A. Lack of orientation and direction selectivity in a subgroup of fast-spiking inhibitory interneurons: Cellular and synaptic mechanisms and comparison with other electrophysiological cell types. Cereb. Cortex 18 (2007) 1058-1078
165. Ohki K., Chung S., Ch'ng Y.H., Kara P., and Reid R.C. Functional imaging with cellular resolution reveals precise micro-architecture in visual cortex. Nature 433 (2005) 597-603
166. Okun M., and Lampl I. Instantaneous correlation of excitation and inhibition during ongoing and sensory-evoked activities. Nat. Neurosci. 11 (2008) 535-537
167. Olshausen B.A., and Field D.J. Sparse coding of sensory inputs. Curr. Opin. Neurobiol. 14 (2004) 481-487
168. Pare D., Shink E., Gaudreau H., Destexhe A., and Lang E.J. Impact of spontaneous synaptic activity on the resting properties of cat neocortical pyramidal neurons In vivo. J. Neurophysiol. 79 (1998) 1450-1460
169. Parga N., and Abbott L.F. Network model of spontaneous activity exhibiting synchronous transitions between up and down States. Front Neurosci 1 (2007) 57-66
170. Penttonen M., Kamondi A., Acsady L., and Buzsaki G. Gamma frequency oscillation in the hippocampus of the rat: intracellular analysis in vivo. Eur. J. Neurosci. 10 (1998) 718-728
171. Pesaran B., Pezaris J.S., Sahani M., Mitra P.P., and Andersen R.A. Temporal structure in neuronal activity during working memory in macaque parietal cortex. Nat. Neurosci. 5 (2002) 805-811
172. Pesaran B., Nelson M.J., and Andersen R.A. Free choice activates a decision circuit between frontal and parietal cortex. Nature 453 (2008) 406-409
173. Peters A. Chandelier Cells. In: Peters A., and Jones E.G. (Eds). Cerebral Cortex. Cellular Components of the Cerebral Cortex (1984), Plenum Press, New York 361-379
174. Petersen C.C., Hahn T.T., Mehta M., Grinvald A., and Sakmann B. Interaction of sensory responses with spontaneous depolarization in layer 2/3 barrel cortex. Proc. Natl. Acad. Sci. USA 100 (2003) 13638-13643
175. Petreanu L., Huber D., Sobczyk A., and Svoboda K. Channelrhodopsin-2-assisted circuit mapping of long-range callosal projections. Nat. Neurosci. 10 (2007) 663-668
176. Petreanu L., Mao T., Sternson S.M., and Svoboda K. The subcellular organization of neocortical excitatory connections. Nature 457 (2009) 1142-1145
177. Piwkowska Z., Pospischil M., Brette R., Sliwa J., Rudolph-Lilith M., Bal T., and Destexhe A. Characterizing synaptic conductance fluctuations in cortical neurons and their influence on spike generation. J. Neurosci. Methods 169 (2008) 302-322
178. Pouille F., and Scanziani M. Enforcement of temporal fidelity in pyramidal cells by somatic feed-forward inhibition. Science 293 (2001) 1159-1163
179. Poulet J.F., and Petersen C.C. Internal brain state regulates membrane potential synchrony in barrel cortex of behaving mice. Nature 454 (2008) 881-885
180. Prescott S.A., and De Koninck Y. Gain control of firing rate by shunting inhibition: roles of synaptic noise and dendritic saturation. Proc. Natl. Acad. Sci. USA 100 (2003) 2076-2081
181. Priebe N.J., and Ferster D. Inhibition, spike threshold, and stimulus selectivity in primary visual cortex. Neuron 57 (2008) 482-497
182. Priebe N.J., Mechler F., Carandini M., and Ferster D. The contribution of spike threshold to the dichotomy of cortical simple and complex cells. Nat. Neurosci. 7 (2004) 1113-1122
183. Reig R., Gallego R., Nowak L.G., and Sanchez-Vives M.V. Impact of cortical network activity on short-term synaptic depression. Cereb. Cortex 16 (2006) 688-695
184. Reynolds J.H., and Chelazzi L. Attentional modulation of visual processing. Annu. Rev. Neurosci. 27 (2004) 611-647
185. Reynolds J.H., and Heeger D.J. The normalization model of attention. Neuron 61 (2009) 168-185
186. Reynolds J.H., Pasternak T., and Desimone R. Attention increases sensitivity of V4 neurons. Neuron 26 (2000) 703-714
187. Rudolph M., and Destexhe A. A fast-conducting, stochastic integrative mode for neocortical neurons in vivo. J. Neurosci. 23 (2003) 2466-2476
188. Rudolph M., Pelletier J.G., Pare D., and Destexhe A. Characterization of synaptic conductances and integrative properties during electrically induced EEG-activated states in neocortical neurons in vivo. J. Neurophysiol. 94 (2005) 2805-2821
189. Rudolph M., Pospischil M., Timofeev I., and Destexhe A. Inhibition determines membrane potential dynamics and controls action potential generation in awake and sleeping cat cortex. J. Neurosci. 27 (2007) 5280-5290
190. Rutishauser U., and Douglas R.J. State-dependent computation using coupled recurrent networks. Neural Comput. (2008) 10.1162/neco.2008.03-08-734 in press. Published online February 11, 2009
191. Sachdev R.N., Ebner F.F., and Wilson C.J. Effect of subthreshold up and down states on the whisker-evoked response in somatosensory cortex. J. Neurophysiol. 92 (2004) 3511-3521
192. Sakmann B. Patch pipettes are more useful than initially thought: simultaneous pre- and postsynaptic recording from mammalian CNS synapses in vitro and in vivo. Pflugers Arch. 453 (2006) 249-259
193. Salinas E., and Abbott L.F. A model of multiplicative neural responses in parietal cortex. Proc. Natl. Acad. Sci. USA 93 (1996) 11956-11961
194. Salinas E., and Sejnowski T.J. Correlated neuronal activity and the flow of neural information. Nat. Rev. Neurosci. 2 (2001) 539-550
195. Sanchez-Vives M.V., and McCormick D.A. Cellular and network mechanisms of rhythmic recurrent activity in neocortex. Nat. Neurosci. 3 (2000) 1027-1034
196. Sanchez-Vives M.V., Nowak L.G., and McCormick D.A. Membrane mechanisms underlying contrast adaptation in cat area 17 in vivo. J. Neurosci. 20 (2000) 4267-4285
197. Sato T.R., Gray N.W., Mainen Z.F., and Svoboda K. The functional microarchitecture of the mouse barrel cortex. PLoS Biol. 5 (2007) e189
198. Sawatari A., and Callaway E.M. Diversity and cell type specificity of local excitatory connections to neurons in layer 3B of monkey primary visual cortex. Neuron 25 (2000) 459-471
199. Shadlen M.N., and Newsome W.T. The variable discharge of cortical neurons: implications for connectivity, computation, and information coding. J. Neurosci. 18 (1998) 3870-3896
200. Shepherd G.M., and Svoboda K. Laminar and columnar organization of ascending excitatory projections to layer 2/3 pyramidal neurons in rat barrel cortex. J. Neurosci. 25 (2005) 5670-5679
201. Shoham S., O'Connor D.H., and Segev R. How silent is the brain: is there a "dark matter" problem in neuroscience?. J. Comp. Physiol. A Neuroethol. Sens. Neural. Behav. Physiol. 192 (2006) 777-784
202. Shu Y., Hasenstaub A., Badoual M., Bal T., and McCormick D.A. Barrages of synaptic activity control the gain and sensitivity of cortical neurons. J. Neurosci. 23 (2003) 10388-10401
203. Shu Y., Hasenstaub A., and McCormick D.A. Turning on and off recurrent balanced cortical activity. Nature 423 (2003) 288-293
204. Shu Y., Hasenstaub A., Duque A., Yu Y., and McCormick D.A. Modulation of intracortical synaptic potentials by presynaptic somatic membrane potential. Nature 441 (2006) 761-765
205. Shu Y., Duque A., Yu Y., Haider B., and McCormick D.A. Properties of action-potential initiation in neocortical pyramidal cells: evidence from whole cell axon recordings. J. Neurophysiol. 97 (2007) 746-760
206. Silberberg G., and Markram H. Disynaptic inhibition between neocortical pyramidal cells mediated by Martinotti cells. Neuron 53 (2007) 735-746
207. Singer W., and Gray C.M. Visual feature integration and the temporal correlation hypothesis. Annu. Rev. Neurosci. 18 (1995) 555-586
208. Sirota A., Montgomery S., Fujisawa S., Isomura Y., Zugaro M., and Buzsaki G. Entrainment of neocortical neurons and gamma oscillations by the hippocampal theta rhythm. Neuron 60 (2008) 683-697
209. Sjostrom P.J., Rancz E.A., Roth A., and Hausser M. Dendritic excitability and synaptic plasticity. Physiol. Rev. 88 (2008) 769-840
210. Softky W.R., and Koch C. The highly irregular firing of cortical cells is inconsistent with temporal integration of random EPSPs. J. Neurosci. 13 (1993) 334-350
211. Sohya K., Kameyama K., Yanagawa Y., Obata K., and Tsumoto T. GABAergic neurons are less selective to stimulus orientation than excitatory neurons in layer II/III of visual cortex, as revealed by in vivo functional Ca2+ imaging in transgenic mice. J. Neurosci. 27 (2007) 2145-2149
212. Song S., Sjostrom P.J., Reigl M., Nelson S., and Chklovskii D.B. Highly nonrandom features of synaptic connectivity in local cortical circuits. PLoS Biol. 3 (2005) e68
213. Steriade M., Nunez A., and Amzica F. Intracellular analysis of relations between the slow (< 1 Hz) neocortical oscillation and other sleep rhythms of the electroencephalogram. J. Neurosci. 13 (1993) 3266-3283
214. Steriade M., Nunez A., and Amzica F. A novel slow (< 1 Hz) oscillation of neocortical neurons in vivo: depolarizing and hyperpolarizing components. J. Neurosci. 13 (1993) 3252-3265
215. Steriade M., Timofeev I., and Grenier F. Natural waking and sleep states: a view from inside neocortical neurons. J. Neurophysiol. 85 (2001) 1969-1985
216. Stern E.A., Kincaid A.E., and Wilson C.J. Spontaneous subthreshold membrane potential fluctuations and action potential variability of rat corticostriatal and striatal neurons in vivo. J. Neurophysiol. 77 (1997) 1697-1715
217. Stuart G., Schiller J., and Sakmann B. Action potential initiation and propagation in rat neocortical pyramidal neurons. J. Physiol. 505 (1997) 617-632
218. Sundberg K.A., Mitchell J.F., and Reynolds J.H. Spatial attention modulates center-surround interactions in macaque visual area v4. Neuron 61 (2009) 952-963
219. Svoboda K., and Yasuda R. Principles of two-photon excitation microscopy and its applications to neuroscience. Neuron 50 (2006) 823-839
220. Swadlow H.A. Thalamocortical control of feed-forward inhibition in awake somatosensory 'barrel' cortex. Philos. Trans. R. Soc. Lond. B Biol. Sci. 357 (2002) 1717-1727
221. Swadlow H.A., Beloozerova I.N., and Sirota M.G. Sharp, local synchrony among putative feed-forward inhibitory interneurons of rabbit somatosensory cortex. J. Neurophysiol. 79 (1998) 567-582
222. Tahvildari B., Alonso A.A., and Bourque C.W. Ionic basis of ON and OFF persistent activity in layer III lateral entorhinal cortical principal neurons. J. Neurophysiol. 99 (2008) 2006-2011
223. Thomson A.M., Bannister A.P., Mercer A., and Morris O.T. Target and temporal pattern selection at neocortical synapses. Philos. Trans. R. Soc. Lond. B Biol. Sci. 357 (2002) 1781-1791
224. Thurley K., Senn W., and Luscher H.R. Dopamine increases the gain of the input-output response of rat prefrontal pyramidal neurons. J. Neurophysiol. 99 (2008) 2985-2997
225. Tiesinga P., Fellous J.M., and Sejnowski T.J. Regulation of spike timing in visual cortical circuits. Nat. Rev. Neurosci. 9 (2008) 97-107
226. Timofeev I., Grenier F., Bazhenov M., Sejnowski T.J., and Steriade M. Origin of slow cortical oscillations in deafferented cortical slabs. Cereb. Cortex 10 (2000) 1185-1199
227. Timofeev I., Grenier F., and Steriade M. Disfacilitation and active inhibition in the neocortex during the natural sleep-wake cycle: an intracellular study. Proc. Natl. Acad. Sci. USA 98 (2001) 1924-1929
228. Treue S., and Martinez Trujillo J.C. Feature-based attention influences motion processing gain in macaque visual cortex. Nature 399 (1999) 575-579
229. Tsujimoto S., Genovesio A., and Wise S.P. Transient neuronal correlations underlying goal selection and maintenance in prefrontal cortex. Cereb. Cortex 18 (2008) 2748-2761
230. van Vreeswijk C., and Sompolinsky H. Chaos in neuronal networks with balanced excitatory and inhibitory activity. Science 274 (1996) 1724-1726
231. Varela J.A., Song S., Turrigiano G.G., and Nelson S.B. Differential depression at excitatory and inhibitory synapses in visual cortex. J. Neurosci. 19 (1999) 4293-4304
232. Vogels T.P., and Abbott L.F. Gating multiple signlas through detailed balance of excitation and inhibition in spiking networks. Nat. Neurosci. 12 (2009) 483-491
233. Vogels T.P., Rajan K., and Abbott L.F. Neural network dynamics. Annu. Rev. Neurosci. 28 (2005) 357-376
234. Volgushev M., Chauvette S., Mukovski M., and Timofeev I. Precise long-range synchronization of activity and silence in neocortical neurons during slow-wave oscillations. J. Neurosci. 26 (2006) 5665-5672
235. Wang X.J. Decision making in recurrent neuronal circuits. Neuron 60 (2008) 215-234
236. Waters J., and Helmchen F. Background synaptic activity is sparse in neocortex. J. Neurosci. 26 (2006) 8267-8277
237. Wehr M., and Zador A.M. Balanced inhibition underlies tuning and sharpens spike timing in auditory cortex. Nature 426 (2003) 442-446
238. Wilent W.B., and Contreras D. Dynamics of excitation and inhibition underlying stimulus selectivity in rat somatosensory cortex. Nat. Neurosci. 8 (2005) 1364-1370
239. Williams S.R. Spatial compartmentalization and functional impact of conductance in pyramidal neurons. Nat. Neurosci. 7 (2004) 961-967
240. Williford T., and Maunsell J.H. Effects of spatial attention on contrast response functions in macaque area V4. J. Neurophysiol. 96 (2006) 40-54
241. Wilson C.J., and Kawaguchi Y. The origins of two-state spontaneous membrane potential fluctuations of neostriatal spiny neurons. J. Neurosci. 16 (1996) 2397-2410
242. Womelsdorf T., Schoffelen J.M., Oostenveld R., Singer W., Desimone R., Engel A.K., and Fries P. Modulation of neuronal interactions through neuronal synchronization. Science 316 (2007) 1609-1612
243. Wong K.F., Huk A.C., Shadlen M.N., and Wang X.J. Neural circuit dynamics underlying accumulation of time-varying evidence during perceptual decision making. Front. Comput. Neurosci. 1 (2007) 6
244. Worgotter F., Suder K., Zhao Y., Kerscher N., Eysel U.T., and Funke K. State-dependent receptive-field restructuring in the visual cortex. Nature 396 (1998) 165-168
245. Yoshimura Y., Dantzker J.L., and Callaway E.M. Excitatory cortical neurons form fine-scale functional networks. Nature 433 (2005) 868-873
246. Yu Y., Shu Y., and McCormick D.A. Cortical action potential backpropagation explains spike threshold variability and rapid-onset kinetics. J. Neurosci. 28 (2008) 7260-7272
247. Zemelman B.V., Lee G.A., and Miesenbock G. Selective photostimulation of genetically chARGed neurons. Neuron 33 (2002) 15-22
248. Zhang F., Aravanis A.M., Adamantidis A., de Lecea L., and Deisseroth K. Circuit-breakers: optical technologies for probing neural signals and systems. Nat. Rev. Neurosci. 8 (2007) 577-581