The γ secretase-generated carboxyl-terminal domain of the amyloid precursor protein induces apoptosis via Tip60 in H4 cells

Journal of Biological Chemistry

Volumn 277, Issue 32, 2002, Pages 28530-28536

  Kinoshita, Ayae ^a   Whelan, Christa M ^a   Berezovska, Oksana ^a   Hyman, Bradley T ^a,b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b Dept Neurol Massachusetts Gen H   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOXYLATION; CELL MEMBRANES; CELLS; DISEASE CONTROL; ENERGY TRANSFER; ENZYMES; FLUORESCENCE; NEUROLOGY;

AMYLOID PRECURSOR PROTEINS (APP); CELL DEATH; CONFOCAL MICROSCOPY; NEURODEGENERATION;

PROTEINS;

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; GAMMA SECRETASE; HISTONE ACETYLTRANSFERASE; HISTONE ACETYLTRANSFERASE TIP60; PROTEIN FE65; UNCLASSIFIED DRUG; ACYLTRANSFERASE; ASPARTIC PROTEINASE; BACE1 PROTEIN, HUMAN; HTATIP PROTEIN, HUMAN; LACTATE DEHYDROGENASE; PROTEINASE; SECRETASE;

APOPTOSIS; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL DEATH; CELL STRAIN; CONFOCAL MICROSCOPY; CONTROLLED STUDY; ENZYME ACTIVITY; FLUORESCENCE RESONANCE ENERGY TRANSFER; HUMAN; HUMAN CELL; NICK END LABELING; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; ALZHEIMER DISEASE; ANIMAL; CELL CULTURE; CELL NUCLEUS; CHEMISTRY; DIMERIZATION; ENERGY TRANSFER; GENE VECTOR; GENETIC TRANSFECTION; IMMUNOHISTOCHEMISTRY; METABOLISM; PROTEIN BINDING; PROTEIN TERTIARY STRUCTURE; RABBIT; SPECTROFLUOROMETRY; TIME;

ACETYLTRANSFERASES; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; APOPTOSIS; ASPARTIC ENDOPEPTIDASES; CELL NUCLEUS; DIMERIZATION; ENDOPEPTIDASES; ENERGY TRANSFER; GENETIC VECTORS; HISTONE ACETYLTRANSFERASES; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; L-LACTATE DEHYDROGENASE; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RABBITS; SPECTROMETRY, FLUORESCENCE; TIME FACTORS; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0037047434     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M203372200     Document Type: Article

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