Loss of microRNA cluster miR-29a/b-1 in sporadic Alzheimer's disease correlates with increased BACE1/β-secretase expression

Proceedings of the National Academy of Sciences of the United States of America

Volumn 105, Issue 17, 2008, Pages 6415-6420

  Hébert, Sébastien S ^a,b   Horré, Katrien ^a,b   Nicolaï, Laura ^a,b   Papadopoulou, Aikaterini S ^a,b   Mandemakers, Wim ^a,b   Silahtaroglu, Asli N ^c   Kauppinen, Sakari ^c,d   Delacourte, André ^e   De Strooper, Bart ^a,b  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^c UNIVERSITY OF COPENHAGEN   (Denmark)

^d Santaris Pharma AS   (Denmark)

^e INSERM   (France)

Author keywords

Amyloid; Neurodegeneration; Noncoding RNA

Indexed keywords

AMYLOID PRECURSOR PROTEIN; BETA SECRETASE; BETA SECRETASE 1; MICRORNA; AMYLOID BETA PROTEIN; ASPARTIC PROTEINASE; BACE1 PROTEIN, HUMAN; SECRETASE;

3' UNTRANSLATED REGION; ALZHEIMER DISEASE; ARTICLE; BRAIN DEVELOPMENT; BRAIN NERVE CELL; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME REGULATION; HUMAN; HUMAN CELL; IN VITRO STUDY; PRIORITY JOURNAL; PROTEIN EXPRESSION; ANIMAL; BRAIN; CELL LINE; ENZYMOLOGY; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MOUSE; PATHOLOGY; UPREGULATION;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ASPARTIC ENDOPEPTIDASES; BRAIN; CELL LINE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HUMANS; MICE; MICRORNAS; UP-REGULATION;

EID: 44049108170     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0710263105     Document Type: Article

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