-
1
-
-
3042857903
-
Alzheimer's disease
-
Cummings JL. Alzheimer's disease. N. Engl. J. Med. 351(1), 56-67 (2004).
-
(2004)
N. Engl. J. Med.
, vol.351
, Issue.1
, pp. 56-67
-
-
Cummings, J.L.1
-
2
-
-
33748536734
-
LR11/SorLA expression is reduced in sporadic Alzheimer disease but not in familial Alzheimer disease
-
Dodson SE, Gearing M, Lippa CF, Montine TJ, Levey AI, Lah JJ. LR11/SorLA expression is reduced in sporadic Alzheimer disease but not in familial Alzheimer disease. J. Neuropathol. Exp. Neurol. 65(9), 866-872 (2006).
-
(2006)
J. Neuropathol. Exp. Neurol.
, vol.65
, Issue.9
, pp. 866-872
-
-
Dodson, S.E.1
Gearing, M.2
Lippa, C.F.3
Montine, T.J.4
Levey, A.I.5
Lah, J.J.6
-
3
-
-
77953448164
-
Genetics of Alzheimer's disease: Recent advances
-
Avramopoulos D. Genetics of Alzheimer's disease: recent advances. Genome Med. 1(3), 34 (2009).
-
(2009)
Genome Med
, vol.1
, Issue.3
, pp. 34
-
-
Avramopoulos, D.1
-
4
-
-
0029946212
-
Analysis of the episodic memory deficit in early Alzheimer's disease: Evidence from the doors and people test
-
Greene JD, Baddeley AD, Hodges JR. Analysis of the episodic memory deficit in early Alzheimer's disease: evidence from the doors and people test. Neuropsychologia 34(6), 537-551 (1996).
-
(1996)
Neuropsychologia
, vol.34
, Issue.6
, pp. 537-551
-
-
Greene, J.D.1
Baddeley, A.D.2
Hodges, J.R.3
-
5
-
-
0027312981
-
Neuropsychological patterns and language deficits in 20 consecutive cases of autopsy-confirmed Alzheimer's disease
-
Price BH, Gurvit H, Weintraub S, Geula C, Leimkuhler E, Mesulam M. Neuropsychological patterns and language deficits in 20 consecutive cases of autopsy-confirmed Alzheimer's disease. Arch. Neurol. 50, 931-937 (1993).
-
(1993)
Arch. Neurol.
, vol.50
, pp. 931-937
-
-
Price, B.H.1
Gurvit, H.2
Weintraub, S.3
Geula, C.4
Leimkuhler, E.5
Mesulam, M.6
-
6
-
-
0031697956
-
Clock drawing test in very mild Alzheimer's disease
-
Esteban-Santillan C, Praditsuwan R, Ueda H, Geldmacher DS. Clock drawing test in very mild Alzheimer's disease. J. Am. Geriatr. Soc. 46(10), 1266-1269 (1998).
-
(1998)
J. Am. Geriatr. Soc.
, vol.46
, Issue.10
, pp. 1266-1269
-
-
Esteban-Santillan, C.1
Praditsuwan, R.2
Ueda, H.3
Geldmacher, D.S.4
-
7
-
-
0033832022
-
Introduction to behavioural and psychological symptoms of dementia (BPSD
-
Finkel S. Introduction to behavioural and psychological symptoms of dementia (BPSD). Int. J. Geriatr. Psychiatry 15(Suppl. 1), S2-S4 (2000).
-
(2000)
Int. J. Geriatr. Psychiatry
, vol.15
, Issue.SUPPL. 1
-
-
Finkel, S.1
-
8
-
-
0025142124
-
Psychiatric symptoms and nursing home placement of patients with Alzheimer's disease
-
Steele C, Rovner B, Chase GA, Folstein M. Psychiatric symptoms and nursing home placement of patients with Alzheimer's disease. Am. J. Psychiatry 147(8), 1049-1051 (1990).
-
(1990)
Am. J. Psychiatry
, vol.147
, Issue.8
, pp. 1049-1051
-
-
Steele, C.1
Rovner, B.2
Chase, G.A.3
Folstein, M.4
-
9
-
-
0000293742
-
Über eine eigenartige Erkrankung der Himrinde
-
Alzheimer A. Über eine eigenartige Erkrankung der Himrinde. Allg. Z Psychiat. Med. 64, 146-148 (1907).
-
(1907)
Allg. Z Psychiat. Med.
, vol.64
, pp. 146-148
-
-
Alzheimer, A.1
-
10
-
-
0023109592
-
Amyloid b protein gene: CDNA, mRNA distribution, and genetic linkage near the Alzheimer locus
-
Tanzi RE, Gusella JF, Watkins PC et al. Amyloid b protein gene: cDNA, mRNA distribution, and genetic linkage near the Alzheimer locus. Science 235(4791), 880-884 (1987).
-
(1987)
Science
, vol.235
, Issue.4791
, pp. 880-884
-
-
Tanzi, R.E.1
Gusella, J.F.2
Watkins, P.C.3
-
11
-
-
0031633953
-
Mechanisms of neurofibrillary degeneration and the formation of neurofibrillary tangles
-
Iqbal K, Alonso AC, Gong CX et al. Mechanisms of neurofibrillary degeneration and the formation of neurofibrillary tangles. J. Neural. Transm. Suppl. 53, 169-180 (1998).
-
(1998)
J. Neural. Transm. Suppl.
, vol.53
, pp. 169-180
-
-
Iqbal, K.1
Alonso, A.C.2
Gong, C.X.3
-
12
-
-
67649805281
-
Amyloid precursor protein transgenic mouse models and Alzheimer's disease: Understanding the paradigms, limitations, and contributions
-
Kokjohn TA, Roher AE. Amyloid precursor protein transgenic mouse models and Alzheimer's disease: understanding the paradigms, limitations, and contributions. Alzheimers Dement. 5(4), 340-347 (2009).
-
(2009)
Alzheimers Dement
, vol.5
, Issue.4
, pp. 340-347
-
-
Kokjohn, T.A.1
Roher, A.E.2
-
13
-
-
0042888866
-
Mouse models of Alzheimer's disease: The long and filamentous road
-
Phinney AL, Horne P, Yang J, Janus C, Bergeron C, Westaway D. Mouse models of Alzheimer's disease: the long and filamentous road. Neurol. Res. 25(6), 590-600 (2003).
-
(2003)
Neurol. Res.
, vol.25
, Issue.6
, pp. 590-600
-
-
Phinney, A.L.1
Horne, P.2
Yang, J.3
Janus, C.4
Bergeron, C.5
Westaway, D.6
-
14
-
-
53749102630
-
Therapeutic strategies for Alzheimer's disease
-
Barten DM, Albright CF. Therapeutic strategies for Alzheimer's disease. Mol. Neurobiol. 37(2-3), 171-186 (2008).
-
(2008)
Mol. Neurobiol.
, vol.37
, Issue.2-3
, pp. 171-186
-
-
Barten, D.M.1
Albright, C.F.2
-
15
-
-
46749128245
-
Elderly patients with dementia-related symptoms of severe agitation and aggression: Consensus statement on treatment options, clinical trials methodology, and policy
-
Salzman C, Jeste DV, Meyer R, et al. Elderly patients with dementia-related symptoms of severe agitation and aggression: consensus statement on treatment options, clinical trials methodology, and policy. J. Clin. Psychiatry 69(6), 889-898 (2008).
-
(2008)
J. Clin. Psychiatry
, vol.69
, Issue.6
, pp. 889-898
-
-
Salzman, C.1
Jeste, D.V.2
Meyer, R.3
-
16
-
-
40749160944
-
Disease-modifying therapies in Alzheimer's disease
-
Salloway S, Mintzer J, Weiner MF, Cummings JL. Disease-modifying therapies in Alzheimer's disease. Alzheimers Dement. 4(2), 65-79 (2008).
-
(2008)
Alzheimers Dement
, vol.4
, Issue.2
, pp. 65-79
-
-
Salloway, S.1
Mintzer, J.2
Weiner, M.F.3
Cummings, J.L.4
-
17
-
-
77957730965
-
Genome-wide association studies in Alzheimer's disease
-
Bertram L, Tanzi RE. Genome-wide association studies in Alzheimer's disease. Hum. Mol. Genet. 18(R2), R137-R145 (2009).
-
(2009)
Hum. Mol. Genet.
, vol.18
, Issue.R2
-
-
Bertram, L.1
Tanzi, R.E.2
-
18
-
-
0026088977
-
Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease
-
Goate A, Chartier-Harlin MC, Mullan M et al. Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease. Nature 349, 704-706 (1991). (Pubitemid 21912142)
-
(1991)
Nature
, vol.349
, Issue.6311
, pp. 704-706
-
-
Goate, A.1
Chartier-Harlin, M.-C.2
Mullan, M.3
Brown, J.4
Crawford, F.5
Fldani, L.6
Giuffra, L.7
Haynes, A.8
Irving, N.9
James, L.10
Mant, R.11
Newton, P.12
Rooke, K.13
Roques, P.14
Talbot, C.15
Pericak-Vance, M.16
Roses, A.17
Williamson, R.18
Rossor, M.19
Owen, M.20
Hardy, J.21
more..
-
19
-
-
0029004341
-
Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease
-
Sherrington R, Rogaev EI, Liang Y et al. Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease. Nature 375, 754-760 (1995).
-
(1995)
Nature
, vol.375
, pp. 754-760
-
-
Sherrington, R.1
Rogaev, E.I.2
Liang, Y.3
-
20
-
-
0029150716
-
A familial Alzheimer's disease locus on chromosome 1
-
Levy-Lahad E, Wijsman EM, Nemens E et al. A familial Alzheimer's disease locus on chromosome 1. Science 269 970-973 (1995).
-
(1995)
Science
, vol.269
, pp. 970-973
-
-
Levy-Lahad, E.1
Wijsman, E.M.2
Nemens, E.3
-
21
-
-
13944276825
-
Twenty years of the Alzheimer's disease amyloid hypothesis: A genetic perspective
-
Tanzi RE, Bertram L. Twenty years of the Alzheimer's disease amyloid hypothesis: a genetic perspective. Cell 120(4), 545-555 (2005).
-
(2005)
Cell
, vol.120
, Issue.4
, pp. 545-555
-
-
Tanzi, R.E.1
Bertram, L.2
-
22
-
-
26944475934
-
Molecular diagnosis of autosomal dominant early onset Alzheimer's disease: An update
-
Raux G, Guyant-Maréchal L, Martin C et al. Molecular diagnosis of autosomal dominant early onset Alzheimer's disease: an update. J. Med. Genet. 42(10), 793-795 (2005).
-
(2005)
J. Med. Genet.
, vol.42
, Issue.10
, pp. 793-795
-
-
Raux, G.1
Guyant-Maréchal, L.2
Martin, C.3
-
23
-
-
27744509435
-
Molecular genetics of Alzheimer's disease and aging
-
Cacabelos R, Fernandez-Novoa L, Lombardi V, Kubota Y, Takeda M. Molecular genetics of Alzheimer's disease and aging. Methods Find. Exp. Clin. Pharmacol. 27(Suppl. A), 1-573 (2005).
-
(2005)
Methods Find. Exp. Clin. Pharmacol.
, vol.27
, Issue.SUPPL. A
, pp. 1-573
-
-
Cacabelos, R.1
Fernandez-Novoa, L.2
Lombardi, V.3
Kubota, Y.4
Takeda, M.5
-
24
-
-
41149125591
-
Pharmacogenomics and therapeutic prospects in dementia
-
Cacabelos R. Pharmacogenomics and therapeutic prospects in dementia. Eur. Arch. Psychiatry Clin. Neurosci. 258(Suppl. 1), 28-47 (2008).
-
(2008)
Eur. Arch. Psychiatry Clin. Neurosci.
, vol.258
, Issue.SUPPL. 1
, pp. 28-47
-
-
Cacabelos, R.1
-
25
-
-
18844479720
-
Heritability for Alzheimer's disease: The study of dementia in Swedish twins
-
Gatz M, Pedersen NL, Berg S et al. Heritability for Alzheimer's disease: the study of dementia in Swedish twins. J. Gerontol. A Biol. Sci. Med. Sci. 52(2), M117-M125 (1997).
-
(1997)
J. Gerontol. A Biol. Sci. Med. Sci.
, vol.52
, Issue.2
-
-
Gatz, M.1
Pedersen, N.L.2
Berg, S.3
-
26
-
-
11844257540
-
Complete ascertainment of dementia in the Swedish Twin Registry: The HARMONY study
-
Gatz M, Fratiglioni L, Johansson B et al. Complete ascertainment of dementia in the Swedish Twin Registry: the HARMONY study. Neurobiol. Aging 26(4), 439-447 (2005).
-
(2005)
Neurobiol. Aging
, vol.26
, Issue.4
, pp. 439-447
-
-
Gatz, M.1
Fratiglioni, L.2
Johansson, B.3
-
27
-
-
0030892582
-
Alzheimer's disease in twins
-
Räihä I, Kaprio J, Koskenvuo M, Rajala T, Sourander L. Alzheimer's disease in twins. Biomed. Pharmacother. 51(3), 101-104 (1997).
-
(1997)
Biomed. Pharmacother.
, vol.51
, Issue.3
, pp. 101-104
-
-
Räihä, I.1
Kaprio, J.2
Koskenvuo, M.3
Rajala, T.4
Sourander, L.5
-
28
-
-
0031957815
-
Complete genomic screen in late-onset familial Alzheimer's disease
-
Pericak-Vance MA, Bass ML, Yamaoka LH et al. Complete genomic screen in late-onset familial Alzheimer's disease. Neurobiol. Aging 19(1 Suppl.), S39-S42 (1998).
-
(1998)
Neurobiol. Aging
, vol.19
, Issue.1 SUPPL.
-
-
Pericak-Vance, M.A.1
Bass, M.L.2
Yamaoka, L.H.3
-
29
-
-
0032899712
-
A full genome scan for late onset Alzheimer's disease
-
Kehoe P, Wavrant-De Vrieze F, Crook R et al. A full genome scan for late onset Alzheimer's disease. Hum. Mol. Genet. 8(2), 237-245 (1999).
-
(1999)
Hum. Mol. Genet.
, vol.8
, Issue.2
, pp. 237-245
-
-
Kehoe, P.1
Wavrant-De Vrieze, F.2
Crook, R.3
-
30
-
-
70349558522
-
Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease
-
Harold D, Abraham R, Hollingworth P et al. Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease. Nat. Genet. 41(10), 1088-1093 (2009).
-
(2009)
Nat. Genet.
, vol.41
, Issue.10
, pp. 1088-1093
-
-
Harold, D.1
Abraham, R.2
Hollingworth, P.3
-
31
-
-
0025735884
-
Linkage studies in familial Alzheimer disease: Evidence for chromosome 19 linkage
-
Pericak-Vance MA, Bebout JL, Gaskell PCJ et al. Linkage studies in familial Alzheimer disease: evidence for chromosome 19 linkage. Am. J. Hum. Genet. 48(6), 1034-1050 (1991).
-
(1991)
Am. J. Hum. Genet.
, vol.48
, Issue.6
, pp. 1034-1050
-
-
Pericak-Vance, M.A.1
Bebout, J.L.2
Gaskell, P.C.J.3
-
32
-
-
0027194791
-
Gene dose of apolipoprotein e type 4 allele and the risk of Alzheimer's disease in late onset families
-
Corder EH, Saunders AM, Strittmatter WJ et al. Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families. Science 261(5123), 921-923 (1993).
-
(1993)
Science
, vol.261
, Issue.5123
, pp. 921-923
-
-
Corder, E.H.1
Saunders, A.M.2
Strittmatter, W.J.3
-
33
-
-
0027327267
-
Association of apolipoprotein E allele ε4 with late-onset familial and sporadic Alzheimer's disease
-
Saunders AM, Strittmatter WJ, Schmechel D et al. Association of apolipoprotein E allele e 4 with late-onset familial and sporadic Alzheimer's disease. Neurology 43(8), 1467-1472 (1993). (Pubitemid 23230526)
-
(1993)
Neurology
, vol.43
, Issue.8
, pp. 1467-1472
-
-
Saunders, A.M.1
Strittmatter, W.J.2
Schmechel, D.3
St. George-Hyslop, P.H.4
Pericak-Vance, M.A.5
Joo, S.H.6
Rosi, B.L.7
Gusella, J.F.8
Crapper-MacLachlan, D.R.9
Alberts, M.J.10
Hulette, C.11
Crain, B.12
Goldgaber, D.13
Roses, A.D.14
-
34
-
-
0027407565
-
Apolipoprotein E: High-avidity binding to b-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease
-
Strittmatter WJ, Saunders AM, Schmechel D et al. Apolipoprotein E: high-avidity binding to b-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease. Proc. Natl Acad. Sci. USA 90, 1977-1981 (1993).
-
(1993)
Proc. Natl Acad. Sci. USA
, vol.90
, pp. 1977-1981
-
-
Strittmatter, W.J.1
Saunders, A.M.2
Schmechel, D.3
-
35
-
-
0032461761
-
Apolipoprotein e and Alzheimer's disease. The tip of the susceptibility iceberg
-
Roses AD. Apolipoprotein E and Alzheimer's disease. The tip of the susceptibility iceberg. Ann. NY Acad. Sci. 855, 738-743 (1998).
-
(1998)
Ann. NY Acad. Sci.
, vol.855
, pp. 738-743
-
-
Roses, A.D.1
-
36
-
-
68249134074
-
The role of apolipoprotein e in Alzheimer's disease
-
Kim J, Basak JM, Holtzman DM. The role of apolipoprotein E in Alzheimer's disease. Neuron 63(3), 287-303 (2009).
-
(2009)
Neuron
, vol.63
, Issue.3
, pp. 287-303
-
-
Kim, J.1
Basak, J.M.2
Holtzman, D.M.3
-
37
-
-
0031054674
-
Brain infarction and the clinical expression of Alzheimer disease. The Nun Study
-
Snowdon DA, Greiner LH, Mortimer JA, Riley KP, Greiner PA, Markesbery WR. Brain infarction and the clinical expression of Alzheimer disease. The Nun Study. JAMA 277(10), 813-817 (1997).
-
(1997)
JAMA
, vol.277
, Issue.10
, pp. 813-817
-
-
Snowdon, D.A.1
Greiner, L.H.2
Mortimer, J.A.3
Riley, K.P.4
Greiner, P.A.5
Markesbery, W.R.6
-
38
-
-
13244274911
-
Analysis of data from the US National Alzheimer's Coordinating Center
-
Honig LS, Kukull W, Mayeux R. Atherosclerosis and AD: analysis of data from the US National Alzheimer's Coordinating Center. Neurology 64(3), 494-500 (2005). (Pubitemid 40189869)
-
(2005)
Neurology
, vol.64
, Issue.3
, pp. 494-500
-
-
Honig, L.S.1
Kukull, W.2
Mayeux, R.3
-
39
-
-
0035897938
-
Midlife vascular risk factors and Alzheimer's disease in later life: Longitudinal, population based study
-
Kivipelto M, Helkala E-L, Laakso MP et al. Midlife vascular risk factors and Alzheimer's disease in later life: longitudinal, population based study. BMJ 322(7300), 1447-1451 (2001).
-
(2001)
BMJ
, vol.322
, Issue.7300
, pp. 1447-1451
-
-
Kivipelto, M.1
Helkala, E.-L.2
Laakso, M.P.3
-
40
-
-
26444463825
-
Obesity and vascular risk factors at midlife and the risk of dementia and Alzheimer disease
-
DOI 10.1001/archneur.62.10.1556
-
Kivipelto M, Ngandu T, Fratiglioni L et al. Obesity and vascular risk factors at midlife and the risk of dementia and Alzheimer disease. Arch. Neurol. 62(10), 1556-1560 (2005). (Pubitemid 41434560)
-
(2005)
Archives of Neurology
, vol.62
, Issue.10
, pp. 1556-1560
-
-
Kivipelto, M.1
Ngandu, T.2
Fratiglioni, L.3
Viitanen, M.4
Kareholt, I.5
Winblad, B.6
Helkala, E.-L.7
Tuomilehto, J.8
Soininen, H.9
Nissinen, A.10
-
42
-
-
33646595017
-
Vascular disease and risk factors, rate of progression, and survival in Alzheimer's disease
-
Bhargava D, Weiner MF, Hynan LS, Diaz-Arrastia R, Lipton AM. Vascular disease and risk factors, rate of progression, and survival in Alzheimer's disease. J. Geriatr. Psychiatry Neurol. 19(2), 78-82 (2006).
-
(2006)
J. Geriatr. Psychiatry Neurol.
, vol.19
, Issue.2
, pp. 78-82
-
-
Bhargava, D.1
Weiner, M.F.2
Hynan, L.S.3
Diaz-Arrastia, R.4
Lipton, A.M.5
-
43
-
-
33847791727
-
Is inhibition of the renin-angiotensin system a new treatment option for Alzheimer's disease?
-
Kehoe PG, Wilcock GK. Is inhibition of the renin-angiotensin system a new treatment option for Alzheimer's disease? Lancet Neurol. 6(4), 373-378 (2007).
-
(2007)
Lancet Neurol
, vol.6
, Issue.4
, pp. 373-378
-
-
Kehoe, P.G.1
Wilcock, G.K.2
-
44
-
-
57349100336
-
Angiotensin-converting enzyme as a potential target for treatment of Alzheimer's disease: Inhibition or activation?
-
Zou K, Michikawa M. Angiotensin-converting enzyme as a potential target for treatment of Alzheimer's disease: inhibition or activation? Rev. Neurosci. 19(4-5), 203-212 (2008).
-
(2008)
Rev. Neurosci.
, vol.19
, Issue.4-5
, pp. 203-212
-
-
Zou, K.1
Michikawa, M.2
-
45
-
-
67149139988
-
The role of vascular factors in late-onset sporadic Alzheimer's disease. Genetic and molecular aspects
-
Rocchi A, Orsucci D, Tognoni G, Ceravolo R, Siciliano G. The role of vascular factors in late-onset sporadic Alzheimer's disease. Genetic and molecular aspects. Curr. Alzheimer Res. 6(3), 224-237 (2009).
-
(2009)
Curr. Alzheimer Res.
, vol.6
, Issue.3
, pp. 224-237
-
-
Rocchi, A.1
Orsucci, D.2
Tognoni, G.3
Ceravolo, R.4
Siciliano, G.5
-
46
-
-
33845892752
-
Systematic meta-analyses of Alzheimer disease genetic association studies: The AlzGene database
-
Bertram L, McQueen MB, Mullin K, Blacker D, Tanzi RE. Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database. Nat. Genet. 39, 17-23 (2007).
-
(2007)
Nat. Genet.
, vol.39
, pp. 17-23
-
-
Bertram, L.1
McQueen, M.B.2
Mullin, K.3
Blacker, D.4
Tanzi, R.E.5
-
47
-
-
66249141948
-
Alzheimer's disease genetics: Current status and future perspectives
-
Bertram L. Alzheimer's disease genetics: current status and future perspectives. Int. Rev. Neurobiol. 84, 167-184 (2009).
-
(2009)
Int. Rev. Neurobiol.
, vol.84
, pp. 167-184
-
-
Bertram, L.1
-
48
-
-
34249745769
-
GAB2 alleles modify Alzheimer's risk in APOE e4 carriers
-
Reiman EM, Webster JA, Myers AJ et al. GAB2 alleles modify Alzheimer's risk in APOE e4 carriers. Neuron 54(5), 713-720 (2007).
-
(2007)
Neuron
, vol.54
, Issue.5
, pp. 713-720
-
-
Reiman, E.M.1
Webster, J.A.2
Myers, A.J.3
-
49
-
-
38349038412
-
Candidate single-nucleotide polymorphisms from a genomewide association study of Alzheimer disease
-
Li H, Wetten S, Li L et al. Candidate single-nucleotide polymorphisms from a genomewide association study of Alzheimer disease. Arch. Neurol. 65(1), 45-53 (2008).
-
(2008)
Arch. Neurol.
, vol.65
, Issue.1
, pp. 45-53
-
-
Li, H.1
Wetten, S.2
Li, L.3
-
50
-
-
55049142500
-
Genome-wide association analysis reveals putative Alzheimer's disease susceptibility loci in addition to APOE
-
Bertram L, Lange C, Mullin K et al. Genome-wide association analysis reveals putative Alzheimer's disease susceptibility loci in addition to APOE. Am. J. Hum. Genet. 83, 623-632 (2008).
-
(2008)
Am. J. Hum. Genet.
, vol.83
, pp. 623-632
-
-
Bertram, L.1
Lange, C.2
Mullin, K.3
-
51
-
-
58049200536
-
Genome-wide association study implicates a chromosome 12 risk locus for late-onset Alzheimer disease
-
Beecham GW, Martin ER, Li YJ et al. Genome-wide association study implicates a chromosome 12 risk locus for late-onset Alzheimer disease. Am. J. Hum. Genet. 84, 35-43 (2009).
-
(2009)
Am. J. Hum. Genet.
, vol.84
, pp. 35-43
-
-
Beecham, G.W.1
Martin, E.R.2
Li, Y.J.3
-
52
-
-
59149084048
-
Genetic variation in PCDH11X is associated with susceptibility to late-onset Alzheimer's disease
-
Carrasquillo MM, Zou F, Pankratz VS et al. Genetic variation in PCDH11X is associated with susceptibility to late-onset Alzheimer's disease. Nat. Genet. 41(2), 192-198 (2009).
-
(2009)
Nat. Genet.
, vol.41
, Issue.2
, pp. 192-198
-
-
Carrasquillo, M.M.1
Zou, F.2
Pankratz, V.S.3
-
53
-
-
78549264026
-
Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease
-
Lambert J-C, Heath S, Even G et al. Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease. Nat. Genet. 41(10), 1094-1099 (2009).
-
(2009)
Nat. Genet.
, vol.41
, Issue.10
, pp. 1094-1099
-
-
Lambert, J.-C.1
Heath, S.2
Even, G.3
-
54
-
-
77953388335
-
Genetics of Alzheimer disease in the pre- and post-GWAS era
-
Ertekin-Taner N. Genetics of Alzheimer disease in the pre- and post-GWAS era. Alzheimers Res. Ther. 2(1), 3 (2010).
-
(2010)
Alzheimers Res. Ther.
, vol.2
, Issue.1
, pp. 3
-
-
Ertekin-Taner, N.1
-
55
-
-
34447559923
-
Evidence for novel susceptibility genes for late-onset Alzheimer's disease from a genome-wide association study of putative functional variants
-
Grupe A, Abraham R, Li Y et al. Evidence for novel susceptibility genes for late-onset Alzheimer's disease from a genome-wide association study of putative functional variants. Hum. Mol. Genet. 16, 865-873 (2007).
-
(2007)
Hum. Mol. Genet.
, vol.16
, pp. 865-873
-
-
Grupe, A.1
Abraham, R.2
Li, Y.3
-
56
-
-
34047272692
-
A high-density whole-genome association study reveals that APOE is the major susceptibility gene for sporadic late-onset Alzheimer's disease
-
Coon KD, Myers AJ, Craig DW et al. A high-density whole-genome association study reveals that APOE is the major susceptibility gene for sporadic late-onset Alzheimer's disease. J. Clin. Psychiatry 68, 613-618 (2007).
-
(2007)
J. Clin. Psychiatry
, vol.68
, pp. 613-618
-
-
Coon, K.D.1
Myers, A.J.2
Craig, D.W.3
-
57
-
-
58849104938
-
Genome screen of late-onset Alzheimer's extended pedigrees identifies TRPC4AP by haplotype analysis
-
Poduslo SE, Huang R, Huang J, Smith S. Genome screen of late-onset Alzheimer's extended pedigrees identifies TRPC4AP by haplotype analysis. Am. J. Med. Genet. B Neuropsychiatr. Genet. 150B, 50-55 (2009).
-
(2009)
Am. J. Med. Genet. B Neuropsychiatr. Genet.
, vol.150 B
, pp. 50-55
-
-
Poduslo, S.E.1
Huang, R.2
Huang, J.3
Smith, S.4
-
58
-
-
68049148052
-
A genome-wide association study for late-onset Alzheimer's disease using DNA pooling
-
Abraham R, Moskvina V, Sims R et al. A genome-wide association study for late-onset Alzheimer's disease using DNA pooling. BMC Med. Genomics 1, 44 (2008).
-
(2008)
BMC Med. Genomics
, vol.1
, pp. 44
-
-
Abraham, R.1
Moskvina, V.2
Sims, R.3
-
59
-
-
77953912200
-
Examination of the current top candidate genes for AD in a genome-wide association study
-
Feulner TM, Laws SM, Friedrich P et al. Examination of the current top candidate genes for AD in a genome-wide association study. Mol. Psychiatry 15(7), 756-766 (2009).
-
(2009)
Mol. Psychiatry
, vol.15
, Issue.7
, pp. 756-766
-
-
Feulner, T.M.1
Laws, S.M.2
Friedrich, P.3
-
60
-
-
34250304714
-
Amyloid precursor protein and presenilin1 interact with the adaptor GRB2 and modulate ERK 1,2 signaling
-
Nizzari M, Venezia V, Repetto E et al. Amyloid precursor protein and presenilin1 interact with the adaptor GRB2 and modulate ERK 1,2 signaling. J. Biol. Chem. 282(18), 13833-13844 (2007).
-
(2007)
J. Biol. Chem.
, vol.282
, Issue.18
, pp. 13833-13844
-
-
Nizzari, M.1
Venezia, V.2
Repetto, E.3
-
61
-
-
40849102705
-
Association study of the GAB2 gene with the risk of developing Alzheimer's disease
-
Chapuis J, Hannequin D, Pasquier F et al. Association study of the GAB2 gene with the risk of developing Alzheimer's disease. Neurobiol. Dis. 30, 103-106 (2008).
-
(2008)
Neurobiol. Dis.
, vol.30
, pp. 103-106
-
-
Chapuis, J.1
Hannequin, D.2
Pasquier, F.3
-
62
-
-
64049116471
-
Common variation in GRB-associated binding protein 2 (GAB2) and increased risk for Alzheimer dementia
-
Sleegers K, Bettens K, Brouwers N et al. Common variation in GRB-associated binding protein 2 (GAB2) and increased risk for Alzheimer dementia. Hum. Mutat. 30, E338-E344 (2009).
-
(2009)
Hum. Mutat.
, vol.30
-
-
Sleegers, K.1
Bettens, K.2
Brouwers, N.3
-
63
-
-
67349266214
-
GAB2 is not associated with late-onset Alzheimer's disease in Japanese
-
Miyashita A, Arai H, Asada T et al. GAB2 is not associated with late-onset Alzheimer's disease in Japanese. Eur. J. Hum. Genet. 17(5), 682-686 (2009).
-
(2009)
Eur. J. Hum. Genet.
, vol.17
, Issue.5
, pp. 682-686
-
-
Miyashita, A.1
Arai, H.2
Asada, T.3
-
64
-
-
67349256894
-
The GAB2 gene and the risk of Alzheimer's disease: Replication and meta-analysis
-
Ikram MA, Liu F, Oostra BA, Hofman A, van Duijn CM, Breteler MM. The GAB2 gene and the risk of Alzheimer's disease: replication and meta-analysis. Biol. Psychiatry 65(11), 995-999 (2009).
-
(2009)
Biol. Psychiatry
, vol.65
, Issue.11
, pp. 995-999
-
-
Ikram, M.A.1
Liu, F.2
Oostra, B.A.3
Hofman, A.4
Van Duijn, C.M.5
Breteler, M.M.6
-
65
-
-
33846613222
-
The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease
-
Rogaeva E, Meng Y, Lee JH et al. The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease. Nat. Genet. 39(2), 168-177 (2007).
-
(2007)
Nat. Genet.
, vol.39
, Issue.2
, pp. 168-177
-
-
Rogaeva, E.1
Meng, Y.2
Lee, J.H.3
-
66
-
-
0029962505
-
Molecular characterization of a novel human hybrid-type receptor that binds the a2-macroglobulin receptor-associated protein
-
Jacobsen L, Madsen P, Moestrup SK et al. Molecular characterization of a novel human hybrid-type receptor that binds the a2-macroglobulin receptor-associated protein. J. Biol. Chem. 271(49), 31379-31383 (1996).
-
(1996)
J. Biol. Chem.
, vol.271
, Issue.49
, pp. 31379-31383
-
-
Jacobsen, L.1
Madsen, P.2
Moestrup, S.K.3
-
67
-
-
38149008770
-
SORL1 variants and risk of late-onset Alzheimer's disease
-
Li Y, Rowland C, Catanese J et al. SORL1 variants and risk of late-onset Alzheimer's disease. Neurobiol. Dis. 29(2), 293-296 (2008).
-
(2008)
Neurobiol. Dis.
, vol.29
, Issue.2
, pp. 293-296
-
-
Li, Y.1
Rowland, C.2
Catanese, J.3
-
68
-
-
34247177933
-
The association between genetic variants in SORL1 and Alzheimer disease in an urban, multiethnic, community-based cohort
-
Lee JH, Cheng R, Schupf N et al. The association between genetic variants in SORL1 and Alzheimer disease in an urban, multiethnic, community-based cohort. Arch. Neurol. 64(4), 501-506 (2007).
-
(2007)
Arch. Neurol.
, vol.64
, Issue.4
, pp. 501-506
-
-
Lee, J.H.1
Cheng, R.2
Schupf, N.3
-
69
-
-
49849086825
-
SORL1 is genetically associated with increased risk for late-onset Alzheimer disease in the Belgian population
-
Bettens K, Brouwers N, Engelborghs S, De Deyn PP, Van Broeckhoven C, Sleegers K. SORL1 is genetically associated with increased risk for late-onset Alzheimer disease in the Belgian population. Hum. Mutat. 29(5), 769-770 (2008).
-
(2008)
Hum. Mutat.
, vol.29
, Issue.5
, pp. 769-770
-
-
Bettens, K.1
Brouwers, N.2
Engelborghs, S.3
De Deyn, P.P.4
Van Broeckhoven, C.5
Sleegers, K.6
-
70
-
-
45449085214
-
No association of SORL1 SNPs with Alzheimer's disease
-
Minster RL, DeKosky ST, Kamboh MI. No association of SORL1 SNPs with Alzheimer's disease. Neurosci. Lett. 440(2), 190-192 (2008).
-
(2008)
Neurosci. Lett.
, vol.440
, Issue.2
, pp. 190-192
-
-
Minster, R.L.1
Dekosky, S.T.2
Kamboh, M.I.3
-
71
-
-
48649109424
-
Genetic association between SORL1 polymorphisms and Alzheimer's disease in a Japanese population
-
Shibata N, Ohnuma T, Baba H, Higashi S, Nishioka K, Arai H. Genetic association between SORL1 polymorphisms and Alzheimer's disease in a Japanese population. Dement. Geriatr. Cogn. Disord. 26(2), 161-164 (2008).
-
(2008)
Dement. Geriatr. Cogn. Disord.
, vol.26
, Issue.2
, pp. 161-164
-
-
Shibata, N.1
Ohnuma, T.2
Baba, H.3
Higashi, S.4
Nishioka, K.5
Arai, H.6
-
72
-
-
37849034999
-
Sorl1 as an Alzheimer's disease predisposition gene?
-
Webster JA, Myers AJ, Pearson JV et al. Sorl1 as an Alzheimer's disease predisposition gene? Neurodegener. Dis. 5(2), 60-64 (2008).
-
(2008)
Neurodegener. Dis.
, vol.5
, Issue.2
, pp. 60-64
-
-
Webster, J.A.1
Myers, A.J.2
Pearson, J.V.3
-
73
-
-
37149030873
-
Alzheimer's disease: Advances in trafficking
-
Mayeux R, Hyslop PS. Alzheimer's disease: advances in trafficking. Lancet Neurol. 7(1), 2-3 (2008).
-
(2008)
Lancet Neurol
, vol.7
, Issue.1
, pp. 2-3
-
-
Mayeux, R.1
Hyslop, P.S.2
-
74
-
-
34250876949
-
Reduction of sortilin-1 in Alzheimer hippocampus and in cytokine-stressed human brain cells
-
Zhao Y, Cui JG, Lukiw WJ. Reduction of sortilin-1 in Alzheimer hippocampus and in cytokine-stressed human brain cells. Neuroreport 18(11), 1187-1191 (2007).
-
(2007)
Neuroreport
, vol.18
, Issue.11
, pp. 1187-1191
-
-
Zhao, Y.1
Cui, J.G.2
Lukiw, W.J.3
-
75
-
-
37149049553
-
Neuronal LR11/sorLA expression is reduced in mild cognitive impairment
-
Sager KL, Wuu J, Leurgans SE et al. Neuronal LR11/sorLA expression is reduced in mild cognitive impairment. Ann. Neurol. 62(6), 640-647 (2007).
-
(2007)
Ann. Neurol.
, vol.62
, Issue.6
, pp. 640-647
-
-
Sager, K.L.1
Wuu, J.2
Leurgans, S.E.3
-
76
-
-
34447255940
-
The galanin peptide family: Receptor pharmacology, pleiotropic biological actions, and implications in health and disease
-
Lang R, Gundlach AL, Kofler B. The galanin peptide family: receptor pharmacology, pleiotropic biological actions, and implications in health and disease. Pharmacol. Ther. 115(2), 177-207 (2007).
-
(2007)
Pharmacol. Ther.
, vol.115
, Issue.2
, pp. 177-207
-
-
Lang, R.1
Gundlach, A.L.2
Kofler, B.3
-
77
-
-
0023728879
-
Galanin hyperinnervates surviving neurons of the human basal nucleus of meynert in dementias of Alzheimer's and Parkinson's disease: A hypothesis for the role of galanin in accentuating cholinergic dysfunction in dementia
-
Chan-Palay V. Galanin hyperinnervates surviving neurons of the human basal nucleus of meynert in dementias of Alzheimer's and Parkinson's disease: a hypothesis for the role of galanin in accentuating cholinergic dysfunction in dementia. J. Comp. Neurol. 273(4), 543-557 (1988).
-
(1988)
J. Comp. Neurol.
, vol.273
, Issue.4
, pp. 543-557
-
-
Chan-Palay, V.1
-
78
-
-
0027324260
-
Galaninergic innervation of the cholinergic vertical limb of the diagonal band (Ch2) and bed nucleus of the stria terminalis in aging. Alzheimer's disease and Down's syndrome
-
Mufson EJ, Cochran E, Benzing W, Kordower JH. Galaninergic innervation of the cholinergic vertical limb of the diagonal band (Ch2) and bed nucleus of the stria terminalis in aging, Alzheimer's disease and Down's syndrome. Dementia 4(5), 237-250 (1993).
-
(1993)
Dementia
, vol.4
, Issue.5
, pp. 237-250
-
-
Mufson, E.J.1
Cochran, E.2
Benzing, W.3
Kordower, J.H.4
-
79
-
-
0142250857
-
Functional g-secretase complex assembly in Golgi/trans-Golgi network: Interactions among presenilin, nicastrin, Aph1, Pen-2, and g-secretase substrates
-
Baulac S, LaVoie MJ, Kimberly WT et al. Functional g-secretase complex assembly in Golgi/trans-Golgi network: interactions among presenilin, nicastrin, Aph1, Pen-2, and g-secretase substrates. Neurobiol. Dis. 14(2), 194-204 (2003).
-
(2003)
Neurobiol. Dis.
, vol.14
, Issue.2
, pp. 194-204
-
-
Baulac, S.1
Lavoie, M.J.2
Kimberly, W.T.3
-
80
-
-
33750530367
-
Retinoid receptors, transporters, and metabolizers as therapeutic targets in late onset Alzheimer disease
-
Goodman AB. Retinoid receptors, transporters, and metabolizers as therapeutic targets in late onset Alzheimer disease. J. Cell Physiol. 209(3), 598-603 (2006).
-
(2006)
J. Cell Physiol.
, vol.209
, Issue.3
, pp. 598-603
-
-
Goodman, A.B.1
-
81
-
-
0033808650
-
Conservation of PCDHX in mammals; Expression of human X/Y genes predominantly in brain
-
Blanco P, Sargent CA, Boucher CA, Mitchell M, Affara NA. Conservation of PCDHX in mammals; expression of human X/Y genes predominantly in brain. Mamm. Genome 11, 906-914 (2000).
-
(2000)
Mamm. Genome
, vol.11
, pp. 906-914
-
-
Blanco, P.1
Sargent, C.A.2
Boucher, C.A.3
Mitchell, M.4
Affara, N.A.5
-
82
-
-
0034709566
-
Characterization of the tyrosine kinase Tnk1 and its binding with phospholipase C-g1
-
Felschow DM, Civin CI, Hoehn GT. Characterization of the tyrosine kinase Tnk1 and its binding with phospholipase C-g1. Biochem. Biophy. Res. Commun. 273(1), 294-301 (2000).
-
(2000)
Biochem. Biophy. Res. Commun.
, vol.273
, Issue.1
, pp. 294-301
-
-
Felschow, D.M.1
Civin, C.I.2
Hoehn, G.T.3
-
83
-
-
0026069474
-
Oncogenes and signal transduction
-
Cantley LC, Auger KR, Carpenter C et al. Oncogenes and signal transduction. Cell 64(2), 281-302 (1991).
-
(1991)
Cell
, vol.64
, Issue.2
, pp. 281-302
-
-
Cantley, L.C.1
Auger, K.R.2
Carpenter, C.3
-
84
-
-
0344653108
-
Activation of phospholipase C-g by phosphatidylinositol 3,4,5-trisphosphate
-
Bae YS, Cantley LG, Chen C-S, Kim S-R, Kwon K-S, Rhee SG. Activation of phospholipase C-g by phosphatidylinositol 3,4,5-trisphosphate. J. Biol. Chem. 273(8), 4465-4469 (1998).
-
(1998)
J. Biol. Chem.
, vol.273
, Issue.8
, pp. 4465-4469
-
-
Bae, Y.S.1
Cantley, L.G.2
Chen, C.-S.3
Kim, S.-R.4
Kwon, K.-S.5
Rhee, S.G.6
-
85
-
-
0020590006
-
Ram rete testis fluid contains a protein (clusterin) which influences cell-cell interactions in vitro
-
Fritz IB, Burdzy K, Setchell B, Blaschuk O. Ram rete testis fluid contains a protein (clusterin) which influences cell-cell interactions in vitro. Biol. Reprod. 28(5), 1173-1188 (1983).
-
(1983)
Biol. Reprod.
, vol.28
, Issue.5
, pp. 1173-1188
-
-
Fritz, I.B.1
Burdzy, K.2
Setchell, B.3
Blaschuk, O.4
-
86
-
-
0025642562
-
Dynamics of gene expression for a hippocampal glycoprotein elevated in Alzheimer's disease and in response to experimental lesions in rat
-
May PC, Lampert-Etchells M, Johnson SA, Poirier J, Masters JN, Finch CE. Dynamics of gene expression for a hippocampal glycoprotein elevated in Alzheimer's disease and in response to experimental lesions in rat. Neuron 5(6), 831-839 (1990).
-
(1990)
Neuron
, vol.5
, Issue.6
, pp. 831-839
-
-
May, P.C.1
Lampert-Etchells, M.2
Johnson, S.A.3
Poirier, J.4
Masters, J.N.5
Finch, C.E.6
-
87
-
-
70349557788
-
Clusterin: A forgotten player in Alzheimer's disease
-
Nuutinen T, Suuronen T, Kauppinen A, Salminen A. Clusterin: a forgotten player in Alzheimer's disease. Brain Res. Rev. 61(2), 89-104 (2009).
-
(2009)
Brain Res. Rev.
, vol.61
, Issue.2
, pp. 89-104
-
-
Nuutinen, T.1
Suuronen, T.2
Kauppinen, A.3
Salminen, A.4
-
88
-
-
67349127527
-
Meta-analysis of linkage studies for Alzheimer's disease - A web resource
-
Butler AW, Ng MY, Hamshere ML et al. Meta-analysis of linkage studies for Alzheimer's disease - a web resource. Neurobiol. Aging 30(7), 1037-1047 (2009).
-
(2009)
Neurobiol. Aging
, vol.30
, Issue.7
, pp. 1037-1047
-
-
Butler, A.W.1
Ng, M.Y.2
Hamshere, M.L.3
-
89
-
-
0020003845
-
Complement receptor (CR1) deficiency in erythrocytes from patients with systemic lupus erythematosus
-
Iida K, Mornaghi R, Nussenzweig V. Complement receptor (CR1) deficiency in erythrocytes from patients with systemic lupus erythematosus. J. Exp. Med. 155(5), 1427-1438 (1982).
-
(1982)
J. Exp. Med.
, vol.155
, Issue.5
, pp. 1427-1438
-
-
Iida, K.1
Mornaghi, R.2
Nussenzweig, V.3
-
90
-
-
0036679142
-
Prominent neurodegeneration and increased plaque formation in complement-inhibited Alzheimer's mice
-
Wyss-Coray T, Yan F, Lin AH-T et al. Prominent neurodegeneration and increased plaque formation in complement-inhibited Alzheimer's mice. Proc. Natl Acad. Sci. USA 99(16), 10837-10842 (2002).
-
(2002)
Proc. Natl Acad. Sci. USA
, vol.99
, Issue.16
, pp. 10837-10842
-
-
Wyss-Coray, T.1
Yan, F.2
Ah-T, L.3
-
91
-
-
32244435907
-
Role of genes and environments for explaining Alzheimer disease
-
Gatz M, Reynolds CA, Fratiglioni L et al. Role of genes and environments for explaining Alzheimer disease. Arch. Gen. Psychiatry 63, 168-174 (2006).
-
(2006)
Arch. Gen. Psychiatry
, vol.63
, pp. 168-174
-
-
Gatz, M.1
Reynolds, C.A.2
Fratiglioni, L.3
-
92
-
-
32344450824
-
Genomic DNA methylation: The mark and its mediators
-
Klose RJ, Bird AP. Genomic DNA methylation: the mark and its mediators. Trends Biochem. Sci. 31(2), 89-97 (2006).
-
(2006)
Trends Biochem. Sci.
, vol.31
, Issue.2
, pp. 89-97
-
-
Klose, R.J.1
Bird, A.P.2
-
93
-
-
33847076849
-
Chromatin modifications and their function
-
Kouzarides T. Chromatin modifications and their function. Cell 128(4), 693-705 (2007).
-
(2007)
Cell
, vol.128
, Issue.4
, pp. 693-705
-
-
Kouzarides, T.1
-
94
-
-
33847070442
-
The role of chromatin during transcription
-
Li B, Carey M, Workman JL. The role of chromatin during transcription. Cell 128(4), 707-719 (2007).
-
(2007)
Cell
, vol.128
, Issue.4
, pp. 707-719
-
-
Li, B.1
Carey, M.2
Workman, J.L.3
-
95
-
-
4444261409
-
Maternal nutrition and fetal development
-
Wu G, Bazer FW, Cudd TA, Meininger CJ, Spencer TE. Maternal nutrition and fetal development. J. Nutr. 134(9), 2169-2172 (2004).
-
(2004)
J. Nutr.
, vol.134
, Issue.9
, pp. 2169-2172
-
-
Wu, G.1
Bazer, F.W.2
Cudd, T.A.3
Meininger, C.J.4
Spencer, T.E.5
-
96
-
-
63349085390
-
Epigenetics, oxidative stress, and Alzheimer disease
-
Zawia NH, Lahiri DK, Cardozo-Pelaez F. Epigenetics, oxidative stress, and Alzheimer disease. Free Radic. Biol. Med. 46(9), 1241-1249 (2009).
-
(2009)
Free Radic. Biol. Med.
, vol.46
, Issue.9
, pp. 1241-1249
-
-
Zawia, N.H.1
Lahiri, D.K.2
Cardozo-Pelaez, F.3
-
97
-
-
0036145567
-
Dynamic reprogramming of DNA methylation in the early mouse embryo
-
Santos F, Hendrich B, Reik W, Dean W. Dynamic reprogramming of DNA methylation in the early mouse embryo. Dev. Biol. 241(1), 172-182 (2002).
-
(2002)
Dev. Biol.
, vol.241
, Issue.1
, pp. 172-182
-
-
Santos, F.1
Hendrich, B.2
Reik, W.3
Dean, W.4
-
98
-
-
3042747515
-
Early environmental regulation of hippocampal glucocorticoid receptor gene expression: Characterization of intracellular mediators and potential genomic target sites
-
Weaver IC, Diorio J, Seckl JR, Szyf M, Meaney MJ. Early environmental regulation of hippocampal glucocorticoid receptor gene expression: characterization of intracellular mediators and potential genomic target sites. Ann. NY Acad. Sci. 1024, 182-212 (2004).
-
(2004)
Ann. NY Acad. Sci.
, vol.1024
, pp. 182-212
-
-
Weaver, I.C.1
Diorio, J.2
Seckl, J.R.3
Szyf, M.4
Meaney, M.J.5
-
99
-
-
20444411948
-
Dietary protein restriction of pregnant rats induces and folic acid supplementation prevents epigenetic modification of hepatic gene expression in the offspring
-
Lillycrop KA, Phillips ES, Jackson AA, Hanson MA, Burdge GC. Dietary protein restriction of pregnant rats induces and folic acid supplementation prevents epigenetic modification of hepatic gene expression in the offspring. J. Nutr. 135(6), 1382-1386 (2005).
-
(2005)
J. Nutr.
, vol.135
, Issue.6
, pp. 1382-1386
-
-
Lillycrop, K.A.1
Phillips, E.S.2
Jackson, A.A.3
Hanson, M.A.4
Burdge, G.C.5
-
100
-
-
67649867069
-
Epigenetic dysregulation in cognitive disorders
-
Gräff J, Mansuy IM. Epigenetic dysregulation in cognitive disorders. Eur. J. Neurosci. 30(1), 1-8 (2009).
-
(2009)
Eur. J. Neurosci.
, vol.30
, Issue.1
, pp. 1-8
-
-
Gräff, J.1
Mansuy, I.M.2
-
101
-
-
0035816661
-
A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60
-
Cao X, Südhof TC. A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60. Science 293(5527), 115-120 (2001).
-
(2001)
Science
, vol.293
, Issue.5527
, pp. 115-120
-
-
Cao, X.1
Südhof, T.C.2
-
102
-
-
0141429160
-
A CBP binding transcriptional repressor produced by the PS1/e-cleavage of N-cadherin is inhibited by PS1 FAD mutations
-
Marambaud P, Wen PH, Dutt A et al. A CBP binding transcriptional repressor produced by the PS1/e-cleavage of N-cadherin is inhibited by PS1 FAD mutations. Cell 114(5), 635-645 (2003).
-
(2003)
Cell
, vol.114
, Issue.5
, pp. 635-645
-
-
Marambaud, P.1
Wen, P.H.2
Dutt, A.3
-
103
-
-
0347624644
-
Critical loss of CBP/p300 histone acetylase activity by caspase-6 during neurodegeneration
-
Rouaux C, Jokic N, Mbebi C, Boutillier S, Loeffler JP, Boutillier AL. Critical loss of CBP/p300 histone acetylase activity by caspase-6 during neurodegeneration. EMBO J. 22(24), 6537-6549 (2003).
-
(2003)
EMBO J
, vol.22
, Issue.24
, pp. 6537-6549
-
-
Rouaux, C.1
Jokic, N.2
Mbebi, C.3
Boutillier, S.4
Loeffler, J.P.5
Boutillier, A.L.6
-
104
-
-
11144354609
-
Loss of presenilin function causes impairments of memory and synaptic plasticity followed by age-dependent neurodegeneration
-
Saura CA, Choi SY, Beglopoulos V et al. Loss of presenilin function causes impairments of memory and synaptic plasticity followed by age-dependent neurodegeneration. Neuron 42(1), 23-36 (2004).
-
(2004)
Neuron
, vol.42
, Issue.1
, pp. 23-36
-
-
Saura, C.A.1
Choi, S.Y.2
Beglopoulos, V.3
-
105
-
-
34248523169
-
Recovery of learning and memory is associated with chromatin remodelling
-
Fischer A, Sananbenesi F, Wang X, Dobbin M, Tsai LH. Recovery of learning and memory is associated with chromatin remodelling. Nature 447(7141), 178-182 (2007).
-
(2007)
Nature
, vol.447
, Issue.7141
, pp. 178-182
-
-
Fischer, A.1
Sananbenesi, F.2
Wang, X.3
Dobbin, M.4
Tsai, L.H.5
-
106
-
-
0037464488
-
Presenilin 1 gene silencing by S-adenosylmethionine: A treatment for Alzheimer disease?
-
Scarpa S, Fuso A, D'Anselmi F, Cavallaro RA. Presenilin 1 gene silencing by S-adenosylmethionine: a treatment for Alzheimer disease? FEBS Lett. 541(1-3), 145-148 (2003).
-
(2003)
FEBS Lett
, vol.541
, Issue.1-3
, pp. 145-148
-
-
Scarpa, S.1
Fuso, A.2
D'Anselmi, F.3
Cavallaro, R.A.4
-
107
-
-
33747449599
-
Gene silencing through methylation: An epigenetic intervention on Alzheimer disease
-
Scarpa S, Cavallaro RA, D'Anselmi F, Fuso A. Gene silencing through methylation: an epigenetic intervention on Alzheimer disease. J. Alzheimers Dis. 9(4), 407-414 (2006).
-
(2006)
J. Alzheimers Dis.
, vol.9
, Issue.4
, pp. 407-414
-
-
Scarpa, S.1
Cavallaro, R.A.2
D'Anselmi, F.3
Fuso, A.4
-
108
-
-
38149024924
-
Alzheimer's disease (AD)-like pathology in aged monkeys after infantile exposure to environmental metal lead (Pb): Evidence for a developmental origin and environmental link for AD
-
Wu J, Basha MR, Brock B et al. Alzheimer's disease (AD)-like pathology in aged monkeys after infantile exposure to environmental metal lead (Pb): evidence for a developmental origin and environmental link for AD. J. Neurosci. 28(1), 3-9 (2008).
-
(2008)
J. Neurosci.
, vol.28
, Issue.1
, pp. 3-9
-
-
Wu, J.1
Basha, M.R.2
Brock, B.3
-
109
-
-
49949108971
-
Age-specific epigenetic drift in late-onset Alzheimer's disease
-
Wang SC, Oelze B, Schumacher A. Age-specific epigenetic drift in late-onset Alzheimer's disease. PLoS ONE 3(7), e2698 (2008).
-
(2008)
PLoS ONE
, vol.3
, Issue.7
-
-
Wang, S.C.1
Oelze, B.2
Schumacher, A.3
-
110
-
-
0033052929
-
Reduction with age in methylcytosine in the promoter region -224 approximately -101 of the amyloid precursor protein gene in autopsy human cortex
-
Tohgi H, Utsugisawa K, Nagane Y, Yoshimura M, Genda Y, Ukitsu M. Reduction with age in methylcytosine in the promoter region -224 approximately -101 of the amyloid precursor protein gene in autopsy human cortex. Brain Res. Mol. Brain Res. 70(2), 288-292 (1999).
-
(1999)
Brain Res. Mol. Brain Res.
, vol.70
, Issue.2
, pp. 288-292
-
-
Tohgi, H.1
Utsugisawa, K.2
Nagane, Y.3
Yoshimura, M.4
Genda, Y.5
Ukitsu, M.6
-
111
-
-
0034093102
-
PCR amplification in bisulfite methylcytosine mapping in the GC-rich promoter region of amyloid precursor protein gene in autopsy human brain
-
Nagane Y, Utsugisawa K, Tohgi H. PCR amplification in bisulfite methylcytosine mapping in the GC-rich promoter region of amyloid precursor protein gene in autopsy human brain. Brain Res. Brain Res. Protoc. 5(2), 167-171 (2000).
-
(2000)
Brain Res. Brain Res. Protoc.
, vol.5
, Issue.2
, pp. 167-171
-
-
Nagane, Y.1
Utsugisawa, K.2
Tohgi, H.3
-
112
-
-
10644237168
-
S-adenosylmethionine/homocysteine cycle alterations modify DNA methylation status with consequent deregulation of PS1 and BACE and b-amyloid production
-
erratum in: Mol. Cell. Neurosci. 32(4), 419 (2006)
-
Fuso A, Seminara L, Cavallaro RA, D'Anselmi F, Scarpa S. S-adenosylmethionine/homocysteine cycle alterations modify DNA methylation status with consequent deregulation of PS1 and BACE and b-amyloid production. Mol Cell. Neurosci. 28(1), 195-204 (2005); erratum in: Mol. Cell. Neurosci. 32(4), 419 (2006).
-
(2005)
Mol Cell. Neurosci.
, vol.28
, Issue.1
, pp. 195-204
-
-
Fuso, A.1
Seminara, L.2
Cavallaro, R.A.3
D'Anselmi, F.4
Scarpa, S.5
-
113
-
-
70449372172
-
Use of genetic variation as biomarkers for Alzheimer's disease
-
Reitz C, Mayeux R. Use of genetic variation as biomarkers for Alzheimer's disease. Ann. NY Acad. Sci. 1180, 75-96 (2009).
-
(2009)
Ann. NY Acad. Sci.
, vol.1180
, pp. 75-96
-
-
Reitz, C.1
Mayeux, R.2
-
114
-
-
0032492161
-
Multiple threshold model for the onset of Alzheimer's disease in the NAS-NRC twin panel
-
Meyer JM, Breitner JC. Multiple threshold model for the onset of Alzheimer's disease in the NAS-NRC twin panel. Am J. Med. Genet. 81(1), 92-97 (1998).
-
(1998)
Am J. Med. Genet.
, vol.81
, Issue.1
, pp. 92-97
-
-
Meyer, J.M.1
Breitner, J.C.2
-
115
-
-
0038823525
-
The endophenotype concept in psychiatry: Etymology and strategic intentions
-
Gottesman II, Gould TD. The endophenotype concept in psychiatry: etymology and strategic intentions. Am. J. Psychiatry 160(4), 636-645 (2003).
-
(2003)
Am. J. Psychiatry
, vol.160
, Issue.4
, pp. 636-645
-
-
Gottesman, I.I.1
Gould, T.D.2
-
116
-
-
0015541474
-
Genetic theorizing and schizophrenia
-
Gottesman I, Shields J. Genetic theorizing and schizophrenia. Br. J. Psychiatry 122(566), 15-30 (1973).
-
(1973)
Br. J. Psychiatry
, vol.122
, Issue.566
, pp. 15-30
-
-
Gottesman, I.1
Shields, J.2
-
117
-
-
0033595026
-
APOE-e4 count predicts age when prevalence of AD increases, then declines: The Cache County Study
-
erratum in: Neurology 55(1), 161-162 (2000)
-
Breitner JC, Wyse BW, Anthony JC et al. APOE-e4 count predicts age when prevalence of AD increases, then declines: the Cache County Study. Neurology 53(2), 321-331 (1999); erratum in: Neurology 55(1), 161-162 (2000).
-
(1999)
Neurology 53
, vol.2
, pp. 321-331
-
-
Breitner, J.C.1
Wyse, B.W.2
Anthony, J.C.3
-
118
-
-
0030050286
-
Clinical and pathological correlates of apolipoprotein e e4 in Alzheimer's disease
-
Gomez-Isla T, West HL, Rebeck GW et al. Clinical and pathological correlates of apolipoprotein E e4 in Alzheimer's disease. Ann. Neurol. 39(1), 62-70 (1996).
-
(1996)
Ann. Neurol.
, vol.39
, Issue.1
, pp. 62-70
-
-
Gomez-Isla, T.1
West, H.L.2
Rebeck, G.W.3
-
119
-
-
0030462762
-
Apolipoprotein E: Non-cognitive symptoms and cognitive decline in late onset Alzheimer's disease
-
Holmes C, Levy R, McLoughlin DM, Powell JF, Lovestone S. Apolipoprotein E: non-cognitive symptoms and cognitive decline in late onset Alzheimer's disease. J. Neurol. Neurosurg. Psychiatry 61(6), 580-583 (1996).
-
(1996)
J. Neurol. Neurosurg. Psychiatry
, vol.61
, Issue.6
, pp. 580-583
-
-
Holmes, C.1
Levy, R.2
McLoughlin, D.M.3
Powell, J.F.4
Lovestone, S.5
-
120
-
-
8044230698
-
Epidemiological, clinical, and neuropathological study of apolipoprotein E genotype in Alzheimer's disease
-
DOI 10.1111/j.1749-6632.1996.tb32592.x
-
Hyman BT, Gomez-Isla T, Rebeck G et al. Epidemiological, clinical, and neuropathological study of apolipoprotein E genotype in Alzheimer's disease. Ann. NY Acad. Sci. 802, 1-5 (1996). (Pubitemid 27055493)
-
(1996)
Annals of the New York Academy of Sciences
, vol.802
, pp. 1-5
-
-
Hyman, B.T.1
Gomez-Isla, T.2
Rebeck, G.W.3
Briggs, M.4
Chung, H.5
West, H.L.6
Greenberg, S.7
Mui, S.8
Nichols, S.9
Wallace, R.10
Growdon, J.H.11
-
121
-
-
0029893288
-
Apolipoprotein e type 4 allele and Alzheimer's disease: Effect on age at onset and relative risk in different age groups
-
Kurz A, Altland K, Lautenschlager N et al. Apolipoprotein E type 4 allele and Alzheimer's disease: effect on age at onset and relative risk in different age groups. J. Neurol. 243(6), 452-456 (1996).
-
(1996)
J. Neurol.
, vol.243
, Issue.6
, pp. 452-456
-
-
Kurz, A.1
Altland, K.2
Lautenschlager, N.3
-
122
-
-
0029781636
-
Apolipoprotein e and Alzheimer's disease: Strength of association is related to age at onset
-
Murman DL, Foster NL, Kilgore SP, McDonagh CA, Fink JK. Apolipoprotein E and Alzheimer's disease: strength of association is related to age at onset. Dementia 7(5), 251-255 (1996).
-
(1996)
Dementia
, vol.7
, Issue.5
, pp. 251-255
-
-
Murman, D.L.1
Foster, N.L.2
Kilgore, S.P.3
McDonagh, C.A.4
Fink, J.K.5
-
123
-
-
0027282035
-
Apolipoprotein e polymorphism and Alzheimer's disease
-
Poirier J, Davignon J, Bouthillier D, Kogan S, Bertrand P, Gauthier S. Apolipoprotein E polymorphism and Alzheimer's disease. Lancet 342(8873), 697-699 (1993).
-
(1993)
Lancet
, vol.342
, Issue.8873
, pp. 697-699
-
-
Poirier, J.1
Davignon, J.2
Bouthillier, D.3
Kogan, S.4
Bertrand, P.5
Gauthier, S.6
-
124
-
-
0030747771
-
Alzheimer's disease: The genetics of risk
-
58-63, 67-69
-
Roses AD. Alzheimer's disease: the genetics of risk. Hosp. Pract. (Minneap.) 32(7), 51-55, 58-63, 67-69 (1997).
-
(1997)
Hosp. Pract. (Minneap.)
, vol.32
, Issue.7
, pp. 51-55
-
-
Roses, A.D.1
-
125
-
-
19144373595
-
Relative risk of Alzheimer disease and age-at-onset distributions, based on APOE genotypes among elderly African Americans, Caucasians, and Hispanics in New York City
-
Tang MX, Maestre G, Tsai WY et al. Relative risk of Alzheimer disease and age-at-onset distributions, based on APOE genotypes among elderly African Americans, Caucasians, and Hispanics in New York City. Am. J. Hum. Genet. 58(3), 574-584 (1996).
-
(1996)
Am. J. Hum. Genet.
, vol.58
, Issue.3
, pp. 574-584
-
-
Tang, M.X.1
Maestre, G.2
Tsai, W.Y.3
-
126
-
-
0028305380
-
Protective effect of apolipoprotein e type 2 allele for late onset Alzheimer disease
-
Corder E, Saunders A, Risch N et al. Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease. Nat. Genet. 7, 180-184 (1994).
-
(1994)
Nat. Genet.
, vol.7
, pp. 180-184
-
-
Corder, E.1
Saunders, A.2
Risch, N.3
-
127
-
-
63249106838
-
Association of SORL1 gene variants with Alzheimer's disease
-
Kölsch H, Jessen F, Wiltfang J et al. Association of SORL1 gene variants with Alzheimer's disease. Brain Res. 1264, 1-6 (2009).
-
(2009)
Brain Res
, vol.1264
, pp. 1-6
-
-
Kölsch, H.1
Jessen, F.2
Wiltfang, J.3
-
128
-
-
76549113301
-
Sequence variation in SORL1 and dementia risk in Swedes
-
Reynolds C, Hong M-G, Eriksson U et al. Sequence variation in SORL1 and dementia risk in Swedes. Neurogenetics 11(1), 139-142 (2010).
-
(2010)
Neurogenetics
, vol.11
, Issue.1
, pp. 139-142
-
-
Reynolds, C.1
Hong, M.-G.2
Eriksson, U.3
-
129
-
-
58149125252
-
Neuropsychological performance in advanced age: Influences of demographic factors and apolipoprotein E: Findings from the Cache County Memory Study
-
Welsh-Bohmer KA, Ostbye T, Sanders L et al. Neuropsychological performance in advanced age: influences of demographic factors and apolipoprotein E: findings from the Cache County Memory Study. Clin. Neuropsychol. 23(1), 77-99 (2009).
-
(2009)
Clin. Neuropsychol.
, vol.23
, Issue.1
, pp. 77-99
-
-
Welsh-Bohmer, K.A.1
Ostbye, T.2
Sanders, L.3
-
130
-
-
18344371417
-
Does apolipoprotein e influence learning and memory in the nondemented oldest old?
-
Salo A, Ylikoski R, Verkkoniemi A et al. Does apolipoprotein E influence learning and memory in the nondemented oldest old? Int. Psychogeriatr. 13(4), 451-459 (2001).
-
(2001)
Int. Psychogeriatr.
, vol.13
, Issue.4
, pp. 451-459
-
-
Salo, A.1
Ylikoski, R.2
Verkkoniemi, A.3
-
131
-
-
1842298766
-
No association between Apolipoprotein E ε4 allele and rate of decline in Alzheimer's disease
-
Murphy GMJ, Taylor J, Kraemer HC, Yesavage J, Tinklenberg JR. No association between apolipoprotein E e 4 allele and rate of decline in Alzheimer's disease. Am. J. Psychiatry 154(5), 603-608 (1997). (Pubitemid 27197591)
-
(1997)
American Journal of Psychiatry
, vol.154
, Issue.5
, pp. 603-608
-
-
Murphy Jr., G.M.1
Taylor, J.2
Kraemer, H.C.3
Yesavage, J.4
Tinklenberg, J.R.5
-
132
-
-
43249124446
-
APOE e 4 allele predicts faster cognitive decline in mild Alzheimer disease
-
Cosentino S, Scarmeas N, Helzner E et al. APOE e 4 allele predicts faster cognitive decline in mild Alzheimer disease. Neurology 70(19 Pt 2), 1842-1849 (2008).
-
(2008)
Neurology
, vol.70
, Issue.19 PART 2
, pp. 1842-1849
-
-
Cosentino, S.1
Scarmeas, N.2
Helzner, E.3
-
133
-
-
38049143662
-
APOE status and its association to learning and memory performance in middle aged and older Norwegians seeking assessment for memory deficits
-
Wehling E, Lundervold AJ, Standnes B, Gjerstad L, Reinvang I. APOE status and its association to learning and memory performance in middle aged and older Norwegians seeking assessment for memory deficits. Behav. Brain Funct. 3, 57 (2007).
-
(2007)
Behav. Brain Funct.
, vol.3
, pp. 57
-
-
Wehling, E.1
Lundervold, A.J.2
Standnes, B.3
Gjerstad, L.4
Reinvang, I.5
-
134
-
-
0041660781
-
Accelerated memory decline in Alzheimer's disease with apolipoprotein e4 allele
-
Hirono N, Hashimoto M, Yasuda M, Kazui H, Mori E. Accelerated memory decline in Alzheimer's disease with apolipoprotein e4 allele. J. Neuropsychiatry Clin. Neurosci. 15(3), 354-358 (2003).
-
(2003)
J. Neuropsychiatry Clin. Neurosci.
, vol.15
, Issue.3
, pp. 354-358
-
-
Hirono, N.1
Hashimoto, M.2
Yasuda, M.3
Kazui, H.4
Mori, E.5
-
135
-
-
65549141230
-
Gene expression as peripheral biomarkers for sporadic Alzheimer's disease
-
Grünblatt E, Bartl J, Zehetmayer S et al. Gene expression as peripheral biomarkers for sporadic Alzheimer's disease. Alzheimers Dis. 16(3), 627-634 (2009).
-
(2009)
Alzheimers Dis
, vol.16
, Issue.3
, pp. 627-634
-
-
Grünblatt, E.1
Bartl, J.2
Zehetmayer, S.3
-
136
-
-
0031596301
-
5-HT2A and 5-HT2C receptor polymorphisms and psychopathology in late onset Alzheimer's disease
-
Holmes C, Arranz MJ, Powell JF, Collier DA, Lovestone S. 5-HT2A and 5-HT2C receptor polymorphisms and psychopathology in late onset Alzheimer's disease. Hum. Mol. Genet. 7(9), 1507-1509 (1998).
-
(1998)
Hum. Mol. Genet.
, vol.7
, Issue.9
, pp. 1507-1509
-
-
Holmes, C.1
Arranz, M.J.2
Powell, J.F.3
Collier, D.A.4
Lovestone, S.5
-
137
-
-
4043174258
-
Association of the serotonin transporter and receptor gene polymorphisms in neuropsychiatric symptoms in Alzheimer disease
-
Assal F, Alarcon M, Solomon EC, Masterman D, Geschwind DH, Cummings JL. Association of the serotonin transporter and receptor gene polymorphisms in neuropsychiatric symptoms in Alzheimer disease. Arch. Neurol. 61(8), 1249-1253 (2004).
-
(2004)
Arch. Neurol.
, vol.61
, Issue.8
, pp. 1249-1253
-
-
Assal, F.1
Alarcon, M.2
Solomon, E.C.3
Masterman, D.4
Geschwind, D.H.5
Cummings, J.L.6
-
138
-
-
4444287079
-
Psychotic symptoms in Alzheimer's disease are not influenced by polymorphic variation at the dopamine receptor DRD3 gene
-
Craig D, Hart DJ, Carson R, McIlroy SP, Passmore AP. Psychotic symptoms in Alzheimer's disease are not influenced by polymorphic variation at the dopamine receptor DRD3 gene. Neurosci. Lett. 368(1), 33-36 (2004).
-
(2004)
Neurosci. Lett.
, vol.368
, Issue.1
, pp. 33-36
-
-
Craig, D.1
Hart, D.J.2
Carson, R.3
McIlroy, S.P.4
Passmore, A.P.5
-
139
-
-
31544457597
-
Neurotransmitter deficits in behavioural and psychological symptoms of Alzheimer's disease
-
Lanari A, Amenta F, Silvestrelli G, Tomassoni D, Parnetti L. Neurotransmitter deficits in behavioural and psychological symptoms of Alzheimer's disease. Mech. Ageing Dev. 127(2), 158-165 (2006).
-
(2006)
Mech. Ageing Dev.
, vol.127
, Issue.2
, pp. 158-165
-
-
Lanari, A.1
Amenta, F.2
Silvestrelli, G.3
Tomassoni, D.4
Parnetti, L.5
-
140
-
-
34548149724
-
Role of serotonin transporter polymorphisms in the behavioural and psychological symptoms in probable Alzheimer disease patients
-
DOI 10.1159/000107081
-
Pritchard AL, Pritchard CW, Bentham P, Lendon CL. Role of serotonin transporter polymorphisms in the behavioural and psychological symptoms in probable Alzheimer disease patients. Dement. Geriatr. Cogn. Disord. 24(3), 201-206 (2007). (Pubitemid 47312670)
-
(2007)
Dementia and Geriatric Cognitive Disorders
, vol.24
, Issue.3
, pp. 201-206
-
-
Pritchard, A.L.1
Pritchard, C.W.2
Bentham, P.3
Lendon, C.L.4
-
141
-
-
38949161478
-
Role of 5HT 2A and 5HT 2C polymorphisms in behavioural and psychological symptoms of Alzheimer's disease
-
Pritchard AL, Harris J, Pritchard CW et al. Role of 5HT 2A and 5HT 2C polymorphisms in behavioural and psychological symptoms of Alzheimer's disease. Neurobiol. Aging 29(3), 341-347 (2008).
-
(2008)
Neurobiol. Aging
, vol.29
, Issue.3
, pp. 341-347
-
-
Pritchard, A.L.1
Harris, J.2
Pritchard, C.W.3
-
142
-
-
67849133731
-
Dopamine D3 receptor gene polymorphism influences on behavioral and psychological symptoms of dementia (BPSD) in mild dementia of Alzheimer's type
-
Sato N, Ueki A, Ueno H, Shinjo H, Morita Y. Dopamine D3 receptor gene polymorphism influences on behavioral and psychological symptoms of dementia (BPSD) in mild dementia of Alzheimer's type. J. Alzheimers Dis. 17(2), 441-448 (2009).
-
(2009)
J. Alzheimers Dis.
, vol.17
, Issue.2
, pp. 441-448
-
-
Sato, N.1
Ueki, A.2
Ueno, H.3
Shinjo, H.4
Morita, Y.5
-
143
-
-
2942626764
-
Apolipoprotein e e4 allele influences aggressive behaviour in Alzheimer's disease
-
Craig D, Hart DJ, McCool K, McIlroy SP, Passmore AP. Apolipoprotein E e4 allele influences aggressive behaviour in Alzheimer's disease. J. Neurol. Neurosurg. Psychiatry 75(9), 1327-1330 (2004).
-
(2004)
J. Neurol. Neurosurg. Psychiatry
, vol.75
, Issue.9
, pp. 1327-1330
-
-
Craig, D.1
Hart, D.J.2
McCool, K.3
McIlroy, S.P.4
Passmore, A.P.5
-
144
-
-
33846886920
-
The effect of the apolipoprotein e gene polymorphisms and haplotypes on behavioural and psychological symptoms in probable Alzheimer's disease
-
Pritchard AL, Harris J, Pritchard CW et al. The effect of the apolipoprotein E gene polymorphisms and haplotypes on behavioural and psychological symptoms in probable Alzheimer's disease. J. Neurol. Neurosurg. Psychiatry 78(2), 123-126 (2007).
-
(2007)
J. Neurol. Neurosurg. Psychiatry
, vol.78
, Issue.2
, pp. 123-126
-
-
Pritchard, A.L.1
Harris, J.2
Pritchard, C.W.3
-
145
-
-
0032891328
-
Apolipoprotein-E (APO-E) genotype and symptoms of psychosis in Alzheimer's disease
-
Harwood DG, Barker WW, Ownby RL, St George-Hyslop P, Duara R. Apolipoprotein-E (APO-E) genotype and symptoms of psychosis in Alzheimer's disease. Am. J. Geriatr. Psychiatry 7(2), 119-123 (1999).
-
(1999)
Am. J. Geriatr. Psychiatry
, vol.7
, Issue.2
, pp. 119-123
-
-
Harwood, D.G.1
Barker, W.W.2
Ownby, R.L.3
St George-Hyslop, P.4
Duara, R.5
-
146
-
-
0032907475
-
Lack of effect of apolipoprotein e E4 allele on neuropsychiatric manifestations in Alzheimer's disease
-
Hirono N, Mori E, Yasuda M et al. Lack of effect of apolipoprotein E E4 allele on neuropsychiatric manifestations in Alzheimer's disease. J. Neuropsychiatry Clin. Neurosci. 11(1), 66-70 (1999).
-
(1999)
J. Neuropsychiatry Clin. Neurosci.
, vol.11
, Issue.1
, pp. 66-70
-
-
Hirono, N.1
Mori, E.2
Yasuda, M.3
-
147
-
-
0036160489
-
Genotype and phenotype in Alzheimer's disease
-
Holmes C. Genotype and phenotype in Alzheimer's disease. Br. J. Psychiatry 180(2), 131-134 (2002).
-
(2002)
Br. J. Psychiatry
, vol.180
, Issue.2
, pp. 131-134
-
-
Holmes, C.1
-
148
-
-
8644245985
-
Neurobiology and genetics of behavioural syndromes of Alzheimer's disease
-
McIlroy S, Craig D. Neurobiology and genetics of behavioural syndromes of Alzheimer's disease. Curr. Alzheimer Res. 1(2), 135-142 (2004).
-
(2004)
Curr. Alzheimer Res.
, vol.1
, Issue.2
, pp. 135-142
-
-
McIlroy, S.1
Craig, D.2
-
149
-
-
70350765290
-
Investigation of dopamine receptors in susceptibility to behavioural and psychological symptoms in Alzheimer's disease
-
Pritchard AL, Ratcliffe L, Sorour E et al. Investigation of dopamine receptors in susceptibility to behavioural and psychological symptoms in Alzheimer's disease. Int. J. Geriatr. Psychiatry 24(9), 1020-1025 (2009).
-
(2009)
Int. J. Geriatr. Psychiatry
, vol.24
, Issue.9
, pp. 1020-1025
-
-
Pritchard, A.L.1
Ratcliffe, L.2
Sorour, E.3
-
150
-
-
34548555711
-
Genetics of Alzheimer's disease. A rapidly evolving field
-
Serretti A, Olgiati P, De Ronchi D. Genetics of Alzheimer's disease. A rapidly evolving field. J. Alzheimers Dis. 12(1), 73-92 (2007).
-
(2007)
J. Alzheimers Dis.
, vol.12
, Issue.1
, pp. 73-92
-
-
Serretti, A.1
Olgiati, P.2
De Ronchi, D.3
-
151
-
-
0035884059
-
Association between 5-HT(2A) receptor polymorphism and psychotic symptoms in Alzheimer's disease
-
Nacmias B, Tedde A, Forleo P et al. Association between 5-HT(2A) receptor polymorphism and psychotic symptoms in Alzheimer's disease. Biol. Psychiatry 50(6), 472-475 (2001).
-
(2001)
Biol. Psychiatry
, vol.50
, Issue.6
, pp. 472-475
-
-
Nacmias, B.1
Tedde, A.2
Forleo, P.3
-
152
-
-
1042289665
-
Serotoninergic polymorphisms (5-HTTLPR and 5-HT2A): Association studies with psychosis in Alzheimer disease
-
Rocchi A, Micheli D, Ceravolo R et al. Serotoninergic polymorphisms (5-HTTLPR and 5-HT2A): association studies with psychosis in Alzheimer disease. Genet. Test. 7(4), 309-314 (2003).
-
(2003)
Genet. Test.
, vol.7
, Issue.4
, pp. 309-314
-
-
Rocchi, A.1
Micheli, D.2
Ceravolo, R.3
-
153
-
-
3042855136
-
5-HT2A T102C receptor polymorphism and neuropsychiatric symptoms in Alzheimer's disease
-
Lam LCW, Tang NLS, Ma SL, Zhang W, Chiu HFK. 5-HT2A T102C receptor polymorphism and neuropsychiatric symptoms in Alzheimer's disease. Int. J. Geriatr. Psychiatry 19(6), 523-526 (2004).
-
(2004)
Int. J. Geriatr. Psychiatry
, vol.19
, Issue.6
, pp. 523-526
-
-
Lam, L.C.W.1
Tang, N.L.S.2
Ma, S.L.3
Zhang, W.4
Chiu, H.F.K.5
-
154
-
-
33846289947
-
Analysis of the 5HT-2A T102C receptor polymorphism and psychotic symptoms in Alzheimer's disease
-
Craig D, Donnelly C, Hart D, Carson R, Passmore P. Analysis of the 5HT-2A T102C receptor polymorphism and psychotic symptoms in Alzheimer's disease. Am. J. Med. Genet. B Neuropsychiatr. Genet. 144B(1), 126-128 (2007).
-
(2007)
Am. J. Med. Genet. B Neuropsychiatr. Genet.
, vol.144 B
, Issue.1
, pp. 126-128
-
-
Craig, D.1
Donnelly, C.2
Hart, D.3
Carson, R.4
Passmore, P.5
-
155
-
-
70349706063
-
Serotonergic system genes in psychosis of Alzheimer dementia: Meta-analysis
-
Ramanathan S, Glatt SJ. Serotonergic system genes in psychosis of Alzheimer dementia: meta-analysis. Am. J. Geriatr. Psychiatry 17(10), 839-846 (2009).
-
(2009)
Am. J. Geriatr. Psychiatry
, vol.17
, Issue.10
, pp. 839-846
-
-
Ramanathan, S.1
Glatt, S.J.2
-
156
-
-
0035212797
-
Psychosis and aggression in Alzheimer's disease: The effect of dopamine receptor gene variation
-
Holmes C, Smith H, Ganderton R et al. Psychosis and aggression in Alzheimer's disease: the effect of dopamine receptor gene variation. J. Neurol. Neurosurg. Psychiatry 71(6), 777-779 (2001).
-
(2001)
J. Neurol. Neurosurg. Psychiatry
, vol.71
, Issue.6
, pp. 777-779
-
-
Holmes, C.1
Smith, H.2
Ganderton, R.3
-
157
-
-
0031669450
-
Dopamine receptor genetic variation, psychosis, and aggression in Alzheimer disease
-
erratum in: Arch. Neurol. 1359(1336), 1042 (2002)
-
Sweet RA, Nimgaonkar VL, Kamboh MI, Lopez OL, Zhang F, DeKosky ST. Dopamine receptor genetic variation, psychosis, and aggression in Alzheimer disease. Arch. Neurol. 55(10), 1335-1340 (1998); erratum in: Arch. Neurol. 1359(1336), 1042 (2002).
-
(1998)
Arch. Neurol.
, vol.55
, Issue.10
, pp. 1335-1340
-
-
Sweet, R.A.1
Nimgaonkar, V.L.2
Kamboh, M.I.3
Lopez, O.L.4
Zhang, F.5
Dekosky, S.T.6
-
158
-
-
45549085789
-
Taking the next steps in the diagnosis of Alzheimer's disease: The use of biomarkers
-
DeKosky ST. Taking the next steps in the diagnosis of Alzheimer's disease: the use of biomarkers. CNS Spectr. 13(3 Suppl. 3), 7-10 (2008).
-
(2008)
CNS Spectr
, vol.13
, Issue.3 SUPPL. 3
, pp. 7-10
-
-
Dekosky, S.T.1
-
159
-
-
44949221768
-
Increased CSF-BACE 1 activity is associated with ApoE-e 4 genotype in subjects with mild cognitive impairment and Alzheimer's disease
-
Ewers M, Zhong Z, Bürger K et al. Increased CSF-BACE 1 activity is associated with ApoE-e 4 genotype in subjects with mild cognitive impairment and Alzheimer's disease. Brain 131(Pt 5), 1252-1258 (2008).
-
(2008)
Brain
, vol.131
, Issue.PART 5
, pp. 1252-1258
-
-
Ewers, M.1
Zhong, Z.2
Bürger, K.3
-
160
-
-
38049179307
-
Core candidate neurochemical and imaging biomarkers of Alzheimer's disease
-
Hampel H, Bürger K, Teipel SJ, Bokde AL, Zetterberg H, Blennow K. Core candidate neurochemical and imaging biomarkers of Alzheimer's disease. Alzheimers Dement. 4(1), 38-48 (2008).
-
(2008)
Alzheimers Dement
, vol.4
, Issue.1
, pp. 38-48
-
-
Hampel, H.1
Bürger, K.2
Teipel, S.J.3
Bokde, A.L.4
Zetterberg, H.5
Blennow, K.6
-
162
-
-
77949423619
-
Cerebrospinal fluid and plasma biomarkers in Alzheimer disease
-
Blennow K, Hampel H, Weiner DM, Zetterberg H. Cerebrospinal fluid and plasma biomarkers in Alzheimer disease. Nat. Rev. Neurol. 6(3), 131-144 (2010).
-
(2010)
Nat. Rev. Neurol.
, vol.6
, Issue.3
, pp. 131-144
-
-
Blennow, K.1
Hampel, H.2
Weiner, D.M.3
Zetterberg, H.4
-
163
-
-
45249114641
-
Influence of SORL1 gene variants: Association with CSF amyloid-b products in probable Alzheimer's disease
-
Kölsch H, Jessen F, Wiltfang J et al. Influence of SORL1 gene variants: association with CSF amyloid-b products in probable Alzheimer's disease. Neurosci. Lett. 440(1), 68-71 (2008).
-
(2008)
Neurosci. Lett.
, vol.440
, Issue.1
, pp. 68-71
-
-
Kölsch, H.1
Jessen, F.2
Wiltfang, J.3
-
164
-
-
77950545456
-
Effect of apolipoprotein e on biomarkers of amyloid load and neuronal pathology in Alzheimer disease
-
Vemuri P, Wiste HJ, Weigand SD et al. Effect of apolipoprotein E on biomarkers of amyloid load and neuronal pathology in Alzheimer disease. Ann. Neurol. 67(3), 308-316 (2010).
-
(2010)
Ann. Neurol.
, vol.67
, Issue.3
, pp. 308-316
-
-
Vemuri, P.1
Wiste, H.J.2
Weigand, S.D.3
-
165
-
-
77149159754
-
Cortical binding of Pittsburgh Compound B, an endophenotype for genetic studies of Alzheimer's disease
-
Hinrichs AL, Mintun MA, Head D et al. Cortical binding of Pittsburgh Compound B, an endophenotype for genetic studies of Alzheimer's disease. Biol. Psychiatry 67(6), 581-583 (2010).
-
(2010)
Biol. Psychiatry
, vol.67
, Issue.6
, pp. 581-583
-
-
Hinrichs, A.L.1
Mintun, M.A.2
Head, D.3
-
166
-
-
33847204043
-
CSF Ab42, tau and phosphorylated tau, APOE e 4 allele and MCI type in progressive MCI
-
Herukka SK, Helisalmi S, Hallikainen M, Tervo S, Soininen H, Pirttilae T. CSF Ab42, tau and phosphorylated tau, APOE e 4 allele and MCI type in progressive MCI. Neurobiol. Aging 28(4), 507-514 (2007).
-
(2007)
Neurobiol. Aging
, vol.28
, Issue.4
, pp. 507-514
-
-
Herukka, S.K.1
Helisalmi, S.2
Hallikainen, M.3
Tervo, S.4
Soininen, H.5
Pirttilae, T.6
-
167
-
-
62349135758
-
The effects of normal aging and ApoE genotype on the levels of CSF biomarkers for Alzheimer's disease
-
Glodzik-Sobanska L, Pirraglia E, Brys M et al. The effects of normal aging and ApoE genotype on the levels of CSF biomarkers for Alzheimer's disease. Neurobiol. Aging 30(5), 672-681 (2009).
-
(2009)
Neurobiol. Aging
, vol.30
, Issue.5
, pp. 672-681
-
-
Glodzik-Sobanska, L.1
Pirraglia, E.2
Brys, M.3
-
168
-
-
65549102191
-
CSF biomarkers in Alzheimer's disease and controls: Associations with APOE genotype are modified by age
-
Kester MI, Blankenstein MA, Bouwman FH, van Elk EJ, Scheltens P, van der Flier WM. CSF biomarkers in Alzheimer's disease and controls: associations with APOE genotype are modified by age. J. Alzheimers Dis. 16(3), 601-607 (2009).
-
(2009)
J. Alzheimers Dis.
, vol.16
, Issue.3
, pp. 601-607
-
-
Kester, M.I.1
Blankenstein, M.A.2
Bouwman, F.H.3
Van Elk, E.J.4
Scheltens, P.5
Van Der Flier, W.M.6
-
169
-
-
15644363081
-
High cerebrospinal fluid tau and low amyloid b42 levels in the clinical diagnosis of Alzheimer disease and relation to apolipoprotein e genotype
-
Galasko D, Chang L, Motter R et al. High cerebrospinal fluid tau and low amyloid b42 levels in the clinical diagnosis of Alzheimer disease and relation to apolipoprotein E genotype. Arch. Neurol. 55(7), 937-945 (1998).
-
(1998)
Arch. Neurol.
, vol.55
, Issue.7
, pp. 937-945
-
-
Galasko, D.1
Chang, L.2
Motter, R.3
-
170
-
-
0033549069
-
Improved discrimination of AD patients using b-amyloid(1-42) and tau levels in CSF
-
Hulstaert F, Blennow K, Ivanoiu A et al. Improved discrimination of AD patients using b-amyloid(1-42) and tau levels in CSF. Neurology 52(8), 1555-1562 (1999).
-
(1999)
Neurology
, vol.52
, Issue.8
, pp. 1555-1562
-
-
Hulstaert, F.1
Blennow, K.2
Ivanoiu, A.3
-
171
-
-
0034282184
-
Relationship between apoE genotype and CSF b-amyloid (1-42) and tau in patients with probable and definite Alzheimers disease
-
Tapiola T, Pirttilae T, Mehta PD, Alafuzoff I, Lehtovirta M, Soininen H. Relationship between apoE genotype and CSF b-amyloid (1-42) and tau in patients with probable and definite Alzheimers disease. Neurobiol. Aging 21(5), 735-740 (2000).
-
(2000)
Neurobiol. Aging
, vol.21
, Issue.5
, pp. 735-740
-
-
Tapiola, T.1
Pirttilae, T.2
Mehta, P.D.3
Alafuzoff, I.4
Lehtovirta, M.5
Soininen, H.6
-
172
-
-
2942557310
-
APOE e 4 allele is associated with reduced cerebrospinal fluid levels of Ab42
-
Prince JA, Zetterberg H, Andreasen N, Marcusson J, Blennow K. APOE e 4 allele is associated with reduced cerebrospinal fluid levels of Ab42. Neurology 62(11), 2116-2118 (2004).
-
(2004)
Neurology
, vol.62
, Issue.11
, pp. 2116-2118
-
-
Prince, J.A.1
Zetterberg, H.2
Andreasen, N.3
Marcusson, J.4
Blennow, K.5
-
173
-
-
7444271086
-
Cerebrospinal fluid b-amyloid1-42 and tau in control subjects at risk for Alzheimer's disease: The effect of APOE e4 allele
-
Sunderland T, Mirza N, Putnam KT et al. Cerebrospinal fluid b-amyloid1-42 and tau in control subjects at risk for Alzheimer's disease: the effect of APOE e4 allele. Biol. Psychiatry 56(9), 670-676 (2004).
-
(2004)
Biol. Psychiatry
, vol.56
, Issue.9
, pp. 670-676
-
-
Sunderland, T.1
Mirza, N.2
Putnam, K.T.3
-
174
-
-
0036172648
-
Association of CSF apolipoprotein e Ab42 and cognition in Alzheimers disease
-
Riemenschneider M, Schmolke M, Lautenschlager N et al. Association of CSF apolipoprotein E, Ab42 and cognition in Alzheimers disease. Neurobiol. Aging 23(2), 205-211 (2002).
-
(2002)
Neurobiol. Aging
, vol.23
, Issue.2
, pp. 205-211
-
-
Riemenschneider, M.1
Schmolke, M.2
Lautenschlager, N.3
-
175
-
-
27844561678
-
Increased levels of CSF phosphorylated tau in apolipoprotein e e4 carriers with mild cognitive impairment
-
Buerger K, Teipel S, Zinkowski R et al. Increased levels of CSF phosphorylated tau in apolipoprotein E e4 carriers with mild cognitive impairment. Neurosci. Lett. 391(1-2), 48-50 (2005).
-
(2005)
Neurosci. Lett.
, vol.391
, Issue.1-2
, pp. 48-50
-
-
Buerger, K.1
Teipel, S.2
Zinkowski, R.3
-
176
-
-
33846253970
-
Differential CSF biomarker levels in APOE- e4-positive and -negative patients with memory impairment
-
Andersson C, Blennow K, Johansson SE et al. Differential CSF biomarker levels in APOE- e4-positive and -negative patients with memory impairment. Dement. Geriatr. Cogn. Disord. 23(2), 87-95 (2007).
-
(2007)
Dement. Geriatr. Cogn. Disord.
, vol.23
, Issue.2
, pp. 87-95
-
-
Andersson, C.1
Blennow, K.2
Johansson, S.E.3
-
177
-
-
33745828142
-
Age and apolipoprotein E*4 allele effects on cerebrospinal fluid b-amyloid 42 in adults with normal cognition
-
Peskind ER, Li G, Shofer J et al. Age and apolipoprotein E*4 allele effects on cerebrospinal fluid b-amyloid 42 in adults with normal cognition. Arch. Neurol. 63(7), 936-939 (2006).
-
(2006)
Arch. Neurol.
, vol.63
, Issue.7
, pp. 936-939
-
-
Peskind, E.R.1
Li, G.2
Shofer, J.3
-
178
-
-
39449093420
-
Hypometabolism and altered cerebrospinal fluid markers in normal apolipoprotein e E4 carriers with subjective memory complaints
-
Mosconi L, De Santi S, Brys M et al. Hypometabolism and altered cerebrospinal fluid markers in normal apolipoprotein E E4 carriers with subjective memory complaints. Biol. Psychiatry 63(6), 609-618 (2008).
-
(2008)
Biol. Psychiatry
, vol.63
, Issue.6
, pp. 609-618
-
-
Mosconi, L.1
De Santi, S.2
Brys, M.3
-
179
-
-
77649314191
-
APOE predicts amyloid-b but not tau Alzheimer pathology in cognitively normal aging
-
Morris JC, Roe CM, Xiong C et al. APOE predicts amyloid-b but not tau Alzheimer pathology in cognitively normal aging. Ann. Neurol. 67(1), 122-131 (2010).
-
(2010)
Ann. Neurol.
, vol.67
, Issue.1
, pp. 122-131
-
-
Morris, J.C.1
Roe, C.M.2
Xiong, C.3
-
180
-
-
27844601188
-
Genetic association of CDC2 with cerebrospinal fluid tau in Alzheimers disease
-
Johansson A, Zetterberg H, Hampel H et al. Genetic association of CDC2 with cerebrospinal fluid tau in Alzheimers disease. Dement. Geriatr. Cogn. Disord. 20(6), 367-374 (2005).
-
(2005)
Dement. Geriatr. Cogn. Disord.
, vol.20
, Issue.6
, pp. 367-374
-
-
Johansson, A.1
Zetterberg, H.2
Hampel, H.3
-
181
-
-
58649091124
-
Alzheimer's disease risk variants show association with cerebrospinal fluid amyloid b
-
Kauwe J, Wang J, Mayo K et al. Alzheimer's disease risk variants show association with cerebrospinal fluid amyloid b. Neurogenetics 10(1), 13-17 (2009).
-
(2009)
Neurogenetics
, vol.10
, Issue.1
, pp. 13-17
-
-
Kauwe, J.1
Wang, J.2
Mayo, K.3
-
182
-
-
19444361938
-
ACE gene is associated with Alzheimer's disease and atrophy of hippocampus and amygdala
-
Sleegers K, den Heijer T, van Dijk EJ et al. ACE gene is associated with Alzheimer's disease and atrophy of hippocampus and amygdala. Neurobiol. Aging 26(8), 1153-1159 (2005).
-
(2005)
Neurobiol. Aging
, vol.26
, Issue.8
, pp. 1153-1159
-
-
Sleegers, K.1
Den Heijer, T.2
Van Dijk, E.J.3
-
183
-
-
0035824167
-
Positron emission tomography in evaluation of dementia: Regional brain metabolism and long-term outcome
-
Silverman DHS, Small GW, Chang CY et al. Positron emission tomography in evaluation of dementia: regional brain metabolism and long-term outcome. JAMA 286(17), 2120-2127 (2001).
-
(2001)
JAMA
, vol.286
, Issue.17
, pp. 2120-2127
-
-
Silverman, D.H.S.1
Small, G.W.2
Chang, C.Y.3
-
184
-
-
0028950856
-
Apolipoprotein e type 4 allele and cerebral glucose metabolism in relatives at risk for familial Alzheimer disease
-
Small GW, Mazziotta JC, Collins MT et al. Apolipoprotein E type 4 allele and cerebral glucose metabolism in relatives at risk for familial Alzheimer disease. JAMA 273(12), 942-947 (1995).
-
(1995)
JAMA
, vol.273
, Issue.12
, pp. 942-947
-
-
Small, G.W.1
Mazziotta, J.C.2
Collins, M.T.3
-
185
-
-
0029970342
-
Preclinical evidence of Alzheimer's disease in persons homozygous for the e 4 allele for apolipoprotein e
-
Reiman EM, Caselli RJ, Yun LS et al. Preclinical evidence of Alzheimer's disease in persons homozygous for the e 4 allele for apolipoprotein E. N. Engl. J. Med. 334(12), 752-758 (1996).
-
(1996)
N. Engl. J. Med.
, vol.334
, Issue.12
, pp. 752-758
-
-
Reiman, E.M.1
Caselli, R.J.2
Yun, L.S.3
-
186
-
-
12944259210
-
Cerebral metabolic and cognitive decline in persons at genetic risk for Alzheimer's disease
-
Small GW, Ercoli LM, Silverman DHS et al. Cerebral metabolic and cognitive decline in persons at genetic risk for Alzheimer's disease. Proc. Natl Acad. Sci. USA 97(11), 6037-6042 (2000).
-
(2000)
Proc. Natl Acad. Sci. USA
, vol.97
, Issue.11
, pp. 6037-6042
-
-
Small, G.W.1
Ercoli, L.M.2
Silverman, D.H.S.3
-
187
-
-
19944427952
-
Cerebral glucose metabolism in patients with AD and different APOE genotypes
-
Drzezga A, Riemenschneider M, Strassner B et al. Cerebral glucose metabolism in patients with AD and different APOE genotypes. Neurology 64(1), 102-107 (2005).
-
(2005)
Neurology
, vol.64
, Issue.1
, pp. 102-107
-
-
Drzezga, A.1
Riemenschneider, M.2
Strassner, B.3
-
188
-
-
0030907745
-
No difference in cerebral glucose metabolism in patients with Alzheimer disease and differing apolipoprotein e genotypes
-
Corder EH, Jelic V, Basun H et al. No difference in cerebral glucose metabolism in patients with Alzheimer disease and differing apolipoprotein E genotypes. Arch. Neurol. 54(3), 273-277 (1997).
-
(1997)
Arch. Neurol.
, vol.54
, Issue.3
, pp. 273-277
-
-
Corder, E.H.1
Jelic, V.2
Basun, H.3
-
189
-
-
0032458366
-
Lack of association of apolipoprotein e e4 allele dose with cerebral glucose metabolism in Alzheimer disease
-
Hirono N, Mori E, Yasuda M et al. Lack of association of apolipoprotein E e4 allele dose with cerebral glucose metabolism in Alzheimer disease. Alzheimer Dis. Assoc. Disord. 12(4), 362-367 (1998).
-
(1998)
Alzheimer Dis. Assoc. Disord.
, vol.12
, Issue.4
, pp. 362-367
-
-
Hirono, N.1
Mori, E.2
Yasuda, M.3
-
190
-
-
0037065999
-
The effect of APOE e4 allele on cerebral glucose metabolism in AD is a function of age at onset
-
Hirono N, Hashimoto M, Yasuda M et al. The effect of APOE e4 allele on cerebral glucose metabolism in AD is a function of age at onset. Neurology 58(5), 743-750 (2002).
-
(2002)
Neurology
, vol.58
, Issue.5
, pp. 743-750
-
-
Hirono, N.1
Hashimoto, M.2
Yasuda, M.3
-
191
-
-
74949100133
-
APOE e4 genotype and longitudinal changes in cerebral blood flow in normal aging
-
Thambisetty M, Beason-Held L, An Y, Kraut MA, Resnick SM. APOE e4 genotype and longitudinal changes in cerebral blood flow in normal aging. Arch. Neurol. 67(1), 93-98 (2010).
-
(2010)
Arch. Neurol.
, vol.67
, Issue.1
, pp. 93-98
-
-
Thambisetty, M.1
Beason-Held, L.2
An, Y.3
Kraut, M.A.4
Resnick, S.M.5
-
192
-
-
0035055902
-
Single photon emission computed tomography and apolipoprotein e in Alzheimer's disease: Impact of the e4 allele on regional cerebral blood flow
-
Hogh P, Knudsen GM, Kjaer KH, Jorgensen OS, Paulson OB, Waldemar G. Single photon emission computed tomography and apolipoprotein E in Alzheimer's disease: impact of the e4 allele on regional cerebral blood flow. J. Geriatr. Psychiatry Neurol. 14(1), 42-51 (2001).
-
(2001)
J. Geriatr. Psychiatry Neurol.
, vol.14
, Issue.1
, pp. 42-51
-
-
Hogh, P.1
Knudsen, G.M.2
Kjaer, K.H.3
Jorgensen, O.S.4
Paulson, O.B.5
Waldemar, G.6
-
193
-
-
67650175992
-
APOE-4 genotype and neurophysiological vulnerability to Alzheimer's and cognitive aging
-
Bookheimer S, Burggren A. APOE-4 genotype and neurophysiological vulnerability to Alzheimer's and cognitive aging. Annu. Rev. Clin. Psychol. 5(1), 343-362 (2009).
-
(2009)
Annu. Rev. Clin. Psychol.
, vol.5
, Issue.1
, pp. 343-362
-
-
Bookheimer, S.1
Burggren, A.2
-
194
-
-
0034680078
-
Patterns of brain activation in people at risk for Alzheimer's disease
-
Bookheimer SY, Strojwas MH, Cohen MS et al. Patterns of brain activation in people at risk for Alzheimer's disease. N. Engl. J. Med. 343(7), 450-456 (2000).
-
(2000)
N. Engl. J. Med.
, vol.343
, Issue.7
, pp. 450-456
-
-
Bookheimer, S.Y.1
Strojwas, M.H.2
Cohen, M.S.3
-
195
-
-
13244274910
-
FMRI evidence of compensatory mechanisms in older adults at genetic risk for Alzheimer disease
-
Bondi MW, Houston WS, Eyler LT, Brown GG. fMRI evidence of compensatory mechanisms in older adults at genetic risk for Alzheimer disease. Neurology 64(3), 501-508 (2005).
-
(2005)
Neurology
, vol.64
, Issue.3
, pp. 501-508
-
-
Bondi, M.W.1
Houston, W.S.2
Eyler, L.T.3
Brown, G.G.4
-
196
-
-
43849095304
-
Amyloid imaging in Alzheimer's disease
-
Nordberg A. Amyloid imaging in Alzheimer's disease. Neuropsychologia 46(6), 1636-1641 (2008).
-
(2008)
Neuropsychologia
, vol.46
, Issue.6
, pp. 1636-1641
-
-
Nordberg, A.1
-
197
-
-
33845707784
-
PET of brain amyloid and tau in mild cognitive impairment
-
Small GW, Kepe V, Ercoli LM et al. PET of brain amyloid and tau in mild cognitive impairment. N. Engl. J. Med. 355(25), 2652-2663 (2006).
-
(2006)
N. Engl. J. Med.
, vol.355
, Issue.25
, pp. 2652-2663
-
-
Small, G.W.1
Kepe, V.2
Ercoli, L.M.3
-
198
-
-
58149482094
-
Influence of cognitive status, age, and APOE-4 genetic risk on brain FDDNP positron-emission tomography imaging in persons without dementia
-
Small GW, Siddarth P, Burggren AC et al. Influence of cognitive status, age, and APOE-4 genetic risk on brain FDDNP positron-emission tomography imaging in persons without dementia. Arch. Gen. Psychiatry 66(1), 81-87 (2009).
-
(2009)
Arch. Gen. Psychiatry
, vol.66
, Issue.1
, pp. 81-87
-
-
Small, G.W.1
Siddarth, P.2
Burggren, A.C.3
-
199
-
-
67549147148
-
Effect of APOE genotype on amyloid plaque load and gray matter volume in Alzheimer disease
-
Drzezga A, Grimmer T, Henriksen G et al. Effect of APOE genotype on amyloid plaque load and gray matter volume in Alzheimer disease. Neurology 72(17), 1487-1494 (2009).
-
(2009)
Neurology
, vol.72
, Issue.17
, pp. 1487-1494
-
-
Drzezga, A.1
Grimmer, T.2
Henriksen, G.3
-
200
-
-
34248579291
-
Imaging b-amyloid burden in aging and dementia
-
Rowe CC, Ng S, Ackermann U et al. Imaging b-amyloid burden in aging and dementia. Neurology 68(20), 1718-1725 (2007).
-
(2007)
Neurology
, vol.68
, Issue.20
, pp. 1718-1725
-
-
Rowe, C.C.1
Ng, S.2
Ackermann, U.3
-
201
-
-
66149084048
-
Fibrillar amyloid-b burden in cognitively normal people at 3 levels of genetic risk for Alzheimer's disease
-
Reiman EM, Chen K, Liu X et al. Fibrillar amyloid-b burden in cognitively normal people at 3 levels of genetic risk for Alzheimer's disease. Proc. Natl Acad. Sci. USA 106(16), 6820-6825 (2009).
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, Issue.16
, pp. 6820-6825
-
-
Reiman, E.M.1
Chen, K.2
Liu, X.3
-
202
-
-
33750689880
-
Evidence-based evaluation of magnetic resonance imaging as a diagnostic tool in dementia workup
-
Wahlund LO, Almkvist O, Blennow K et al. Evidence-based evaluation of magnetic resonance imaging as a diagnostic tool in dementia workup. Top Magn. Reson. Imaging 16(6), 427-437 (2005).
-
(2005)
Top Magn. Reson. Imaging
, vol.16
, Issue.6
, pp. 427-437
-
-
Wahlund, L.O.1
Almkvist, O.2
Blennow, K.3
-
203
-
-
41149152904
-
Novel MRI techniques in the assessment of dementia
-
Teipel SJ, Meindl T, Grinberg L, Heinsen H, Hampel H. Novel MRI techniques in the assessment of dementia. Eur. J. Nucl. Med. Mol. Imaging 35(Suppl. 1), S58-69 (2008).
-
(2008)
Eur. J. Nucl. Med. Mol. Imaging
, vol.35
, Issue.SUPPL. 1
-
-
Teipel, S.J.1
Meindl, T.2
Grinberg, L.3
Heinsen, H.4
Hampel, H.5
-
204
-
-
0030612735
-
Apolipoprotein e e 4 allele and hippocampal volume in twins with normal cognition
-
Plassman BL, Welsh-Bohmer KA, Bigler ED et al. Apolipoprotein E e 4 allele and hippocampal volume in twins with normal cognition. Neurology 48(4), 985-989 (1997).
-
(1997)
Neurology
, vol.48
, Issue.4
, pp. 985-989
-
-
Plassman, B.L.1
Welsh-Bohmer, K.A.2
Bigler, E.D.3
-
205
-
-
32544448231
-
Reduced hippocampal volume in non-demented carriers of the apolipoprotein e e4: Relation to chronological age and recognition memory
-
Lind J, Larsson A, Persson J et al. Reduced hippocampal volume in non-demented carriers of the apolipoprotein E e4: relation to chronological age and recognition memory. Neurosci. Lett. 396(1), 23-27 (2006).
-
(2006)
Neurosci. Lett.
, vol.396
, Issue.1
, pp. 23-27
-
-
Lind, J.1
Larsson, A.2
Persson, J.3
-
206
-
-
0030473420
-
Apolipoprotein e e4 allele in the normal elderly: Neuropsychologic and brain MRI correlates
-
Schmidt H, Schmidt R, Fazekas F et al. Apolipoprotein E e4 allele in the normal elderly: neuropsychologic and brain MRI correlates. Clin. Genet. 50(5), 293-299 (1996).
-
(1996)
Clin. Genet.
, vol.50
, Issue.5
, pp. 293-299
-
-
Schmidt, H.1
Schmidt, R.2
Fazekas, F.3
-
207
-
-
47049087411
-
Total and regional gray matter volume is not related to APOE*E4 status in a community sample of middle-aged individuals
-
Cherbuin N, Anstey KJ, Sachdev PS et al. Total and regional gray matter volume is not related to APOE*E4 status in a community sample of middle-aged individuals. J. Gerontol. A Biol. Sci. Med. Sci. 63(5), 501-504 (2008).
-
(2008)
J. Gerontol. A Biol. Sci. Med. Sci.
, vol.63
, Issue.5
, pp. 501-504
-
-
Cherbuin, N.1
Anstey, K.J.2
Sachdev, P.S.3
-
208
-
-
70349873189
-
Hippocampal volumes are important predictors for memory function in elderly women
-
Ystad MA, Lundervold AJ, Wehling E et al. Hippocampal volumes are important predictors for memory function in elderly women. BMC Med. Imaging 9, 17 (2009).
-
(2009)
BMC Med. Imaging
, vol.9
, pp. 17
-
-
Ystad, M.A.1
Lundervold, A.J.2
Wehling, E.3
-
209
-
-
0034641255
-
Longitudinal change in hippocampal volume as a function of apolipoprotein e genotype
-
Moffat SD, Szekely CA, Zonderman AB, Kabani NJ, Resnick SM. Longitudinal change in hippocampal volume as a function of apolipoprotein E genotype. Neurology 55(1), 134-136 (2000).
-
(2000)
Neurology
, vol.55
, Issue.1
, pp. 134-136
-
-
Moffat, S.D.1
Szekely, C.A.2
Zonderman, A.B.3
Kabani, N.J.4
Resnick, S.M.5
-
210
-
-
0035956552
-
Effect of apolipoprotein e genotype on hippocampal volume loss in aging healthy women
-
Cohen RM, Small C, Lalonde F, Friz J, Sunderland T. Effect of apolipoprotein E genotype on hippocampal volume loss in aging healthy women. Neurology 57(12), 2223-2228 (2001).
-
(2001)
Neurology
, vol.57
, Issue.12
, pp. 2223-2228
-
-
Cohen, R.M.1
Small, C.2
Lalonde, F.3
Friz, J.4
Sunderland, T.5
-
211
-
-
34250163241
-
Differential cross-sectional and longitudinal impact of APOE genotype on hippocampal volumes in nondemented older adults
-
Jak AJ, Houston WS, Nagel BJ, Corey- Bloom J, Bondi MW. Differential cross-sectional and longitudinal impact of APOE genotype on hippocampal volumes in nondemented older adults. Dement. Geriatr. Cogn. Disord. 23(6), 382-389 (2007).
-
(2007)
Dement. Geriatr. Cogn. Disord.
, vol.23
, Issue.6
, pp. 382-389
-
-
Jak, A.J.1
Houston, W.S.2
Nagel, B.J.3
Corey- Bloom, J.4
Bondi, M.W.5
-
212
-
-
15444344926
-
Hippocampal volumes in cognitively normal persons at genetic risk for Alzheimer's disease
-
Reiman EM, Uecker A, Caselli RJ et al. Hippocampal volumes in cognitively normal persons at genetic risk for Alzheimer's disease. Ann. Neurol. 44(2), 288-291 (1998).
-
(1998)
Ann. Neurol.
, vol.44
, Issue.2
, pp. 288-291
-
-
Reiman, E.M.1
Uecker, A.2
Caselli, R.J.3
-
213
-
-
2642673613
-
Hippocampal atrophy and apolipoprotein e genotype are independently associated with Alzheimer's disease
-
Jack CRJ, Petersen RC, Xu YC et al. Hippocampal atrophy and apolipoprotein E genotype are independently associated with Alzheimer's disease. Ann. Neurol. 43(3), 303-310 (1998).
-
(1998)
Ann. Neurol.
, vol.43
, Issue.3
, pp. 303-310
-
-
Jack, C.R.J.1
Petersen, R.C.2
Xu, Y.C.3
-
214
-
-
0036152408
-
Accelerated hippocampal atrophy in Alzheimer's disease with apolipoprotein e e4 allele
-
Mori E, Lee K, Yasuda M et al. Accelerated hippocampal atrophy in Alzheimer's disease with apolipoprotein E e4 allele. Ann. Neurol. 51(2), 209-214 (2002).
-
(2002)
Ann. Neurol.
, vol.51
, Issue.2
, pp. 209-214
-
-
Mori, E.1
Lee, K.2
Yasuda, M.3
-
215
-
-
65249101314
-
MRI of hippocampal volume loss in early Alzheimer's disease in relation to ApoE genotype and biomarkers
-
Schuff N, Woerner N, Boreta L et al. MRI of hippocampal volume loss in early Alzheimer's disease in relation to ApoE genotype and biomarkers. Brain 132(Pt 4), 1067-1077 (2009).
-
(2009)
Brain
, vol.132
, Issue.PART 4
, pp. 1067-1077
-
-
Schuff, N.1
Woerner, N.2
Boreta, L.3
-
216
-
-
35148859365
-
Baseline predictors of rates of hippocampal atrophy in mild cognitive impairment
-
DOI 10.1212/01.wnl.0000277458.26846.96, PII 0000611420071009000005
-
van de Pol LA, van der Flier WM, Korf ES, Fox NC, Barkhof F, Scheltens P. Baseline predictors of rates of hippocampal atrophy in mild cognitive impairment. Neurology 69(15), 1491-1497 (2007). (Pubitemid 47537855)
-
(2007)
Neurology
, vol.69
, Issue.15
, pp. 1491-1497
-
-
Van De Pol, L.A.1
Van Der Flier, W.M.2
Korf, E.S.C.3
Fox, N.C.4
Barkhof, F.5
Scheltens, P.6
-
217
-
-
33645091234
-
Imaging studies and APOE genotype in persons at risk for Alzheimer's disease
-
Scarmeas N, Stern Y. Imaging studies and APOE genotype in persons at risk for Alzheimer's disease. Curr. Psychiatry Rep. 8(1), 11-17 (2006).
-
(2006)
Curr. Psychiatry Rep.
, vol.8
, Issue.1
, pp. 11-17
-
-
Scarmeas, N.1
Stern, Y.2
-
218
-
-
57649131090
-
The medical and economic roles of pipeline pharmacogenetics: Alzheimer's disease as a model of efficacy and HLA-B*5701 as a model of safety
-
Roses AD. The medical and economic roles of pipeline pharmacogenetics: Alzheimer's disease as a model of efficacy and HLA-B*5701 as a model of safety. Neuropsychopharmacology 34(1), 6-17 (2009).
-
(2009)
Neuropsychopharmacology
, vol.34
, Issue.1
, pp. 6-17
-
-
Roses, A.D.1
-
219
-
-
69949184308
-
A genomewide association study points to multiple loci that predict antidepressant drug treatment outcome in depression
-
Ising M, Lucae S, Binder EB et al. A genomewide association study points to multiple loci that predict antidepressant drug treatment outcome in depression. Arch. Gen. Psychiatry 66(9), 966-975 (2009).
-
(2009)
Arch. Gen. Psychiatry
, vol.66
, Issue.9
, pp. 966-975
-
-
Ising, M.1
Lucae, S.2
Binder, E.B.3
-
220
-
-
49949108534
-
Pharmacogenomics and treatment for dementia induced by Alzheimers disease
-
Gupta M, Kaur H, Grover S, Kukreti R. Pharmacogenomics and treatment for dementia induced by Alzheimers disease. Pharmacogenomics 9(7), 895-903 (2008).
-
(2008)
Pharmacogenomics
, vol.9
, Issue.7
, pp. 895-903
-
-
Gupta, M.1
Kaur, H.2
Grover, S.3
Kukreti, R.4
-
221
-
-
75149138378
-
The pursuit of susceptibility genes for Alzheimer's disease: Progress and prospects
-
Sleegers K, Lambert J-C, Bertram L, Cruts M, Amouyel P, Van Broeckhoven C. The pursuit of susceptibility genes for Alzheimer's disease: progress and prospects. Trends Genet. 26(2), 84-93 (2010).
-
(2010)
Trends Genet
, vol.26
, Issue.2
, pp. 84-93
-
-
Sleegers, K.1
Lambert, J.-C.2
Bertram, L.3
Cruts, M.4
Amouyel, P.5
Van Broeckhoven, C.6
-
222
-
-
0034737298
-
RNAi: Double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals
-
Zamore PD, Tuschl T, Sharp PA, Bartel DP. RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals. Cell 101(1), 25-33 (2000).
-
(2000)
Cell
, vol.101
, Issue.1
, pp. 25-33
-
-
Zamore, P.D.1
Tuschl, T.2
Sharp, P.A.3
Bartel, D.P.4
-
223
-
-
0034673638
-
An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells
-
Hammond SM, Bernstein E, Beach D, Hannon GJ. An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells. Nature 404, 293-296 (2000).
-
(2000)
Nature
, vol.404
, pp. 293-296
-
-
Hammond, S.M.1
Bernstein, E.2
Beach, D.3
Hannon, G.J.4
-
224
-
-
33646190173
-
Gene silencing through RNA interference (RNAi) in vivo: Strategies based on the direct application of siRNAs
-
Aigner A. Gene silencing through RNA interference (RNAi) in vivo: strategies based on the direct application of siRNAs. J. Biotechnology 124(1), 12-25 (2006).
-
(2006)
J. Biotechnology
, vol.124
, Issue.1
, pp. 12-25
-
-
Aigner, A.1
-
225
-
-
33745183812
-
Short interfering RNA (siRNA) as a novel therapeutic Clin
-
Pushparaj PN, Melendez AJ. Short interfering RNA (siRNA) as a novel therapeutic Clin. Exp. Pharmacol. Physiol. 33(5-6), 504-510 (2006).
-
(2006)
Exp. Pharmacol. Physiol.
, vol.33
, Issue.5-6
, pp. 504-510
-
-
Pushparaj, P.N.1
Melendez, A.J.2
-
226
-
-
0345826094
-
BACE1 suppression by RNA interference in primary cortical neurons
-
Kao SC, Krichevsky A, Kosik K, Tsai L-H. BACE1 suppression by RNA interference in primary cortical neurons. J. Biol. Chem. 279, 1942-1949 (2003).
-
(2003)
J. Biol. Chem.
, vol.279
, pp. 1942-1949
-
-
Kao, S.C.1
Krichevsky, A.2
Kosik, K.3
Tsai, L.-H.4
-
227
-
-
76749101192
-
High-content siRNA screening of the kinome identifies kinases involved in Alzheimer's disease-related tau hyperphosphorylation
-
Azorsa D, Robeson RH, Frost D et al. High-content siRNA screening of the kinome identifies kinases involved in Alzheimer's disease-related tau hyperphosphorylation. BMC Genomics 11(1), 25 (2010).
-
(2010)
BMC Genomics
, vol.11
, Issue.1
, pp. 25
-
-
Azorsa, D.1
Robeson, R.H.2
Frost, D.3
-
228
-
-
34147183745
-
RNAi silencing in mouse models of neurodegenerative diseases
-
Farah MH. RNAi silencing in mouse models of neurodegenerative diseases. Curr. Drug Deliv. 4(2), 161-167 (2007).
-
(2007)
Curr. Drug Deliv.
, vol.4
, Issue.2
, pp. 161-167
-
-
Farah, M.H.1
-
229
-
-
38449104482
-
The therapeutic potential of siRNA in gene therapy of neurodegenerative disorders
-
Koutsilieri E, Rethwilm A, Scheller C. The therapeutic potential of siRNA in gene therapy of neurodegenerative disorders. J. Neural Transm. Suppl. 72, 43-49 (2007).
-
(2007)
J. Neural Transm. Suppl.
, vol.72
, pp. 43-49
-
-
Koutsilieri, E.1
Rethwilm, A.2
Scheller, C.3
-
230
-
-
36749049934
-
RNA interference as a tool for Alzheimer's disease therapy
-
Orlacchio A, Bernardi G, Orlacchio A, Martino S. RNA interference as a tool for Alzheimer's disease therapy. Mini Rev. Med. Chem. 7(11), 1166-1176 (2007).
-
(2007)
Mini Rev. Med. Chem.
, vol.7
, Issue.11
, pp. 1166-1176
-
-
Orlacchio, A.1
Bernardi, G.2
Orlacchio, A.3
Martino, S.4
-
231
-
-
1242264290
-
The pharmacogenomics of Alzheimer's disease
-
Crentsil V. The pharmacogenomics of Alzheimer's disease. Ageing Res. Rev. 3(2), 153-169 (2004).
-
(2004)
Ageing Res. Rev.
, vol.3
, Issue.2
, pp. 153-169
-
-
Crentsil, V.1
-
232
-
-
38049115446
-
Apolipoprotein e represents a potent gene-based therapeutic target for the treatment of sporadic Alzheimer's disease
-
Poirier J. Apolipoprotein E represents a potent gene-based therapeutic target for the treatment of sporadic Alzheimer's disease. Alzheimers Dement. 4(1 Suppl. 1), S91-S97 (2008).
-
(2008)
Alzheimers Dement
, vol.4
, Issue.1 SUPPL. 1
-
-
Poirier, J.1
-
233
-
-
4143097904
-
Apolipoprotein e as a target for developing new therapeutics for Alzheimer's disease based on studies from protein. RNA, and regulatory region of the gene
-
Lahiri DK. Apolipoprotein E as a target for developing new therapeutics for Alzheimer's disease based on studies from protein, RNA, and regulatory region of the gene. J. Mol. Neurosci. 23(3), 225-233 (2004).
-
(2004)
J. Mol. Neurosci.
, vol.23
, Issue.3
, pp. 225-233
-
-
Lahiri, D.K.1
-
234
-
-
52449089987
-
Thirty years of Alzheimer's disease genetics: The implications of systematic meta-analyses
-
Bertram L, Tanzi RE. Thirty years of Alzheimer's disease genetics: the implications of systematic meta-analyses. Nat. Rev. Neurosci. 9(10), 768-778 (2008).
-
(2008)
Nat. Rev. Neurosci.
, vol.9
, Issue.10
, pp. 768-778
-
-
Bertram, L.1
Tanzi, R.E.2
-
235
-
-
66249145711
-
The molecular and cellular pathogenesis of dementia of the Alzheimer's type: An overview
-
Luque FA, Jaffe SL. The molecular and cellular pathogenesis of dementia of the Alzheimer's type: an overview. Int. Rev. Neurobiol. 84, 151-165 (2009).
-
(2009)
Int. Rev. Neurobiol.
, vol.84
, pp. 151-165
-
-
Luque, F.A.1
Jaffe, S.L.2
-
236
-
-
43549110738
-
Positron emission tomography imaging in dementia
-
Spec. No 2
-
Herholz K, Carter SF, Jones M. Positron emission tomography imaging in dementia. Br. J. Radiol. 80(Spec. No 2), S160-S167 (2007).
-
(2007)
Br. J. Radiol.
, vol.80
-
-
Herholz, K.1
Carter, S.F.2
Jones, M.3
-
237
-
-
77954239263
-
Biomarkers for Alzheimer's disease: Academic, industry and regulatory perspectives
-
In Press
-
Hampel H, Frank R, Broich K et al. Biomarkers for Alzheimer's disease: academic, industry and regulatory perspectives. Nat. Rev. Drug Discov. (2010) (In Press).
-
(2010)
Nat. Rev. Drug Discov.
-
-
Hampel, H.1
Frank, R.2
Broich, K.3
-
238
-
-
41149109089
-
Amyloid plaque imaging in vivo: Current achievement and future prospects
-
Nordberg A. Amyloid plaque imaging in vivo: current achievement and future prospects. Eur. J. Nucl. Med. Mol. Imaging 35(Suppl. 1), S46-S50 (2008).
-
(2008)
Eur. J. Nucl. Med. Mol. Imaging
, vol.35
, Issue.SUPPL. 1
-
-
Nordberg, A.1
-
239
-
-
70449434560
-
Biological marker candidates of Alzheimer's disease in blood, plasma, and serum
-
Schneider P, Hampel H, Buerger K. Biological marker candidates of Alzheimer's disease in blood, plasma, and serum. CNS Neurosci. Ther. 15(4), 358-374 (2009).
-
(2009)
CNS Neurosci. Ther.
, vol.15
, Issue.4
, pp. 358-374
-
-
Schneider, P.1
Hampel, H.2
Buerger, K.3
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