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Volumn 9, Issue 1, 2003, Pages 3-4

Elevated β-secretase expression and enzymatic activity detected in sporadic Alzheimer disease [1]

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; BETA SECRETASE; COMPLEMENTARY DNA;

EID: 0037236622     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/nm0103-3     Document Type: Letter
Times cited : (631)

References (10)
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    • A pathologic mutation for probable Alzheimer's disease in the APP gene at the N-terminus of β-amyloid
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  • 3
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    • Mutation of the β-amyloid precursor protein in familial Alzheimer's disease
    • Citron, M. et al. Mutation of the β-amyloid precursor protein in familial Alzheimer's disease. Nature 360, 372 (1992).
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    • Citron, M.1
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    • Membrane-anchored aspartyl protease with Alzheimer's disease β-secretase activity
    • Yan, R. et al. Membrane-anchored aspartyl protease with Alzheimer's disease β-secretase activity. Noture 402, 533-537 (1999).
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    • Yan, R.1
  • 5
    • 0033595706 scopus 로고    scopus 로고
    • β-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE
    • Vassar, R. et al. β-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE. Science 286, 735-741 (1999).
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    • Vassar, R.1
  • 6
    • 0035112647 scopus 로고    scopus 로고
    • BACE1 is the major β-secretase for generation of Aβ peptides by neurons
    • Cai, H. et al. BACE1 is the major β-secretase for generation of Aβ peptides by neurons. Noture Neurosci. 4, 233-234 (2001).
    • (2001) Noture Neurosci. , vol.4 , pp. 233-234
    • Cai, H.1
  • 7
    • 0037088652 scopus 로고    scopus 로고
    • Endosomal proteorysis of internalized insulin at the C-terminal region of the β chain by cathepsin D
    • Authier, I. et al. Endosomal proteorysis of internalized insulin at the C-terminal region of the β chain by cathepsin D. J. Biol. Chem. 277, 9437-9446 (2002).
    • (2002) J. Biol. Chem. , vol.277 , pp. 9437-9446
    • Authier, I.1
  • 8
    • 0033518251 scopus 로고    scopus 로고
    • Purification and cloning of amyloid precursor protein β-secretase from human brain
    • Sinha, S. et al. Purification and cloning of amyloid precursor protein β-secretase from human brain. Nature 402, 537-540 (1999).
    • (1999) Nature , vol.402 , pp. 537-540
    • Sinha, S.1
  • 9
    • 0038117796 scopus 로고    scopus 로고
    • Correlation between elevated levels of amyloid β-peptide in the brain and cognitive decline
    • Naslund, I. et al. Correlation between elevated levels of amyloid β-peptide in the brain and cognitive decline. JAMA 283, 1571-1577 (2000).
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    • Molecular isolation of living cortical neurons from rapidly autopsied human elderly brains using DNA-linker magnetic purification system
    • Konishi, Y., Lindholm, K., Yang, L.B., Li, R. & Shen, Y. Molecular isolation of living cortical neurons from rapidly autopsied human elderly brains using DNA-linker magnetic purification system. Am. J. Pathol. 161, 1567-1576 (2002).
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    • Konishi, Y.1    Lindholm, K.2    Yang, L.B.3    Li, R.4    Shen, Y.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.