A critical analysis of new molecular targets and strategies for drug developments in Alzheimer's disease

Current Drug Targets

Volumn 4, Issue 2, 2003, Pages 97-112

  Lahiri, Debomoy K ^a   Farlow, Martin R ^a   Sambamurti, Kumar ^b   Greig, Nigel H ^c   Giacobini, Ezio ^d   Schneider, Lon S ^e  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b MAYO CLINIC   (United States)

^c NATIONAL INSTITUTE ON AGING   (United States)

^d GENEVA UNIVERSITY HOSPITALS   (Switzerland)

^e UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Acetylcholine; Alzheimer's disease; Anticholinesterase; APP gene; Beta amyloid; Cholinergic agents; Cholinesterase; Cholinomimetic drugs; Dementia; NSAID; Oxidative stress; Phenserine; Tau protein

Indexed keywords

ALPHA 2 MACROGLOBULIN; ALPHA CATENIN; ALZHEIMER DISEASE VACCINE; AMYLOID; AMYLOID BETA PROTEIN; ANTIINFLAMMATORY AGENT; ANTIOXIDANT; APOLIPOPROTEIN E; BETA SECRETASE; CARBACHOL; CHOLINERGIC RECEPTOR; CHOLINESTERASE; CHOLINESTERASE INHIBITOR; DIPEPTIDYL CARBOXYPEPTIDASE; DONEPEZIL; ENZYME INHIBITOR; ESTROGEN; GALANTAMINE; GAMMA SECRETASE; HORMONE DERIVATIVE; HYPOCHOLESTEROLEMIC AGENT; INSULINASE; NOOTROPIC AGENT; PRESENILIN 1; PRESENILIN 2; PROTEIN PRECURSOR; RIVASTIGMINE; TACRINE; TAU PROTEIN; UNINDEXED DRUG;

ALZHEIMER DISEASE; BIOCHEMISTRY; BRAIN REGION; CHOLINERGIC SYSTEM; DEGENERATIVE DISEASE; DIAGNOSTIC PROCEDURE; DISEASE ASSOCIATION; DISEASE COURSE; DISEASE MARKER; DRUG ANALYSIS; DRUG EFFICACY; DRUG TARGETING; ELDERLY CARE; ENVIRONMENTAL FACTOR; ENZYME INHIBITION; FAMILIAL DISEASE; GENE MUTATION; HEREDITY; HUMAN; LEARNING; MEDICAL RESEARCH; MEMORY CONSOLIDATION; NEUROBIOLOGY; NEUROFIBRILLARY TANGLE; NUTRITIONAL STATUS; PATHOGENESIS; PATHOPHYSIOLOGY; PRESYNAPTIC NERVE; PROTEIN FUNCTION; QUANTITATIVE ANALYSIS; REVIEW; ANIMAL; DRUG DELIVERY SYSTEM; GENETICS; METABOLISM; METHODOLOGY; PHARMACEUTICS;

ALZHEIMER DISEASE; ANIMALS; DRUG DELIVERY SYSTEMS; HUMANS; TECHNOLOGY, PHARMACEUTICAL;

EID: 0037315878     PISSN: 13894501     EISSN: None     Source Type: Journal    
DOI: 10.2174/1389450033346957     Document Type: Review

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