Functional MRI studies of associative encoding in normal aging, mild cognitive impairment, and Alzheimer's disease

Annals of the New York Academy of Sciences

Volumn 1097, Issue , 2007, Pages 146-155

  Sperling, Reisa ^a,b,c,d  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d Memory Disorders Unit   (United States)

Author keywords

Aging; Alzheimer's disease; fMRI; Hippocampus; Memory

Indexed keywords

AGING; ALZHEIMER DISEASE; BRAIN REGION; CLINICAL ARTICLE; COGNITION; COGNITIVE DEFECT; COMPARATIVE STUDY; CONFERENCE PAPER; CONTROLLED STUDY; DISEASE SEVERITY; FUNCTIONAL MAGNETIC RESONANCE IMAGING; GENETIC RISK; GROUPS BY AGE; HIPPOCAMPUS; HUMAN; LONGITUDINAL STUDY; MEMORY; NEUROIMAGING; PATHOLOGY; PATHOPHYSIOLOGY; PREFRONTAL CORTEX; TEMPORAL LOBE; VALIDATION PROCESS; ANIMAL; BRAIN; GENETICS; GENOMICS; GROWTH, DEVELOPMENT AND AGING; NUCLEAR MAGNETIC RESONANCE IMAGING; POSITRON EMISSION TOMOGRAPHY; REVIEW; RISK FACTOR; SCINTISCANNING;

APOLIPOPROTEIN E;

AGING; ALZHEIMER DISEASE; ANIMALS; APOLIPOPROTEINS E; BRAIN; COGNITION DISORDERS; GENOMICS; HUMANS; MAGNETIC RESONANCE IMAGING; POSITRON-EMISSION TOMOGRAPHY; RISK FACTORS;

EID: 34247556163     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1196/annals.1379.009     Document Type: Conference Paper

References (49)

1. SQUIRE, L.R. & S. ZOLA-MORGAN. 1991. The medial temporal lobe memory system. Science 253: 1380-1386.
2. EICHENBAUM, H., G. SCHOENBAUM, B. YOUNG & M. BUNSEY. 1996. Functional organization of the hippocampal memory system. Proc. Natl. Acad. Sci. USA 93: 13500-13507.
3. ZELINSKI, E.M. & M.J. GILEWSKI. 1988. Assessment of memory complaints by rating scales and questionnaires. Psychopharmacol. Bull. 24: 523-529.
4. LEIRER, V.O., D.G. MORROW, J.I. SHEIKH & G.M. PARIANTE. 1990. Memory skills elders want to improve. Exp. Aging Res. 16: 155-158.
5. MORRIS, J.C., D.W. MCKEEL JR., M. STORANDT, et al. 1991. Very mild Alzheimer's disease: informant-based clinical, psychometric, and pathologic distinction from normal aging [see comments]. Neurology 41: 469-478.
6. FOWLER, K.S., M.M. SALING, E.L. CONWAY, et al. 2002. Paired associate performance in the early detection of DAT. J. Int. Neuropsychol. Soc. 8: 58-71.
7. GALLO, D.A., A.L. SULLIVAN, K.R. DAFFNER, et al. 2004. Associative recognition in Alzheimer's disease: evidence for impaired recall-to-reject. Neuropsychology 18: 556-563.
8. SMALL, S.A., A.S. NAVA, G.M. PERERA, et al. 2001. Circuit mechanisms underlying memory encoding and retrieval in the long axis of the hippocampal formation. Nat. Neurosci. 4: 442-449.
9. ZEINEH, M.M., S.A. ENGEL, P.M. THOMPSON & S.Y. BOOKHEIMER. 2003. Dynamics of the hippocampus during encoding and retrieval of face-name pairs. Science 299: 577-580.
10. KIRWAN, C.B. & C.E. STARK. 2004. Medial temporal lobe activation during encoding and retrieval of novel face-name pairs. Hippocampus 14: 919-930.
11. SPERLING, R.A., J. BATES, A. COCCHIARELLA, et al. 2001. Encoding novel face-name associations: a functional MRI study. Hum. Brain Mapp. 14: 129-139.
12. SPERLING, R.A., D. GREVE, A. DALE, et al. 2002. fMRI detection of pharmacologically induced memory impairment. Proc. Nat. Acad. Sci. 99: 455-460.
13. SPERLING, R., E. CHUA, A. COCCHIARELLA, et al. 2003. Putting names to faces: successful encoding of associative memories activates the anterior hippocampal formation. Neuroimage 20: 1400-1410.
14. SPERLING, R., J. BATES, E. CHUA, et al. 2003. fMRI studies of associative encoding in young and elderly controls and mild AD patients. J. Neurol. Neurosurg. Psychiatry 74: 44-50.
15. RAND-GIOVANNETTI, E., E.F. CHUA, A.E. DRISCOLL, et al. 2006. Hippocampal and neocortical activation during repetitive encoding in older persons. Neurobiol. Aging 27: 173-182.
16. MILLER, S., K. DEPEAU, E. DIAMOND, et al. 2006. fMRI activations and deactivations during successful associative encoding in normal aging. Ann. N. Y. Acad. Sci. This volume.
17. DASELAAR, S.M., S.E. PRINCE & R. CABEZA. 2004. When less means more: deactivations during encoding that predict subsequent memory. Neuroimage 23: 921-927.
18. SMALL, S.A., G.M. PERERA, R. DEL APAZ, et al. 1999. Differential regional dysfunction of the hippocampal formation among elderly with memory decline and Alzheimer's disease. Ann. Neurol. 45: 466-472.
19. ROMBOUTS, S.A., F. BARKHOF, D.J. VELTMAN, et al. 2000. Functional MR imaging in Alzheimer's disease during memory encoding. AJNR Am. J. Neuroradiol. 21: 1869-1875.
20. KATO, T., D. KNOPMAN & H. LIU. 2001. Dissociation of regional activation in mild AD during visual encoding: a functional MRI study. Neurology 57: 812-816.
21. GRON, G., D. BITTNER, B. SCHMITZ, et al. 2002. Subjective memory complaints: objective neural markers in patients with Alzheimer's disease and major depressive disorder. Ann. Neurol. 51: 491-498.
22. MACHULDA, M.M., H.A. WARD, B. BOROWSKI, et al. 2003. Comparison of memory fMRI response among normal, MCI, and Alzheimer's patients. Neurology 61: 500-506.
23. GOLBY, A., G. SILVERBERG, E. RACE, et al. 2005. Memory encoding in Alzheimer's disease: an fMRI study of explicit and implicit memory. Brain 128: 773-787.
24. PARIENTE, J., S. COLE, R. HENSON, et al. 2005. Alzheimer's patients engage an alternative network during a memory task. Ann. Neurol. 58: 870-879.
25. DICKERSON, B.C., D. SALAT, D. GREVE, et al. 2005. Increased hippocampal activation in mild cognitive impairment compared to normal aging and AD. Neurology 65: 404-411.
26. GRADY, C.L., A.R. MCINTOSH, S. BEIG, et al. 2003. Evidence from functional neuroimaging of a compensatory prefrontal network in Alzheimer's disease. J. Neurosci. 23: 986-993.
27. LUSTIG, C., A.Z. SNYDER, M. BHAKTA, et al. 2003. Functional deactivations: change with age and dementia of the Alzheimer type. Proc. Natl. Acad. Sci. USA 100: 14504-14509.
28. GREICIUS, M.D., G. SRIVASTAVA, A.L. REISS & V. MENON. 2004. Default-mode network activity distinguishes Alzheimer's disease from healthy aging: evidence from functional MRI. Proc. Natl. Acad. Sci. USA 101: 4637-4642.
29. ROMBOUTS, S.A., R. GOEKOOP, C.J. STAM, et al. 2005. Delayed rather than decreased BOLD response as a marker for early Alzheimer's disease. Neuroimage 26: 1078-1085.
30. BUCKNER, R.L., A.Z. SNYDER, B.J. SHANNON, et al. 2005. Molecular, structural, and functional characterization of Alzheimer's disease: evidence for a relationship between default activity, amyloid, and memory. J. Neurosci. 25: 7709-7717.
31. PETRELLA, J., S. KRISHNAN, M. SLAVIN, et al. 2006. Mild cognitive impairment: evaluation with 4-T functional MR imaging. Radiology 240: 177-186.
32. RAICHLE, M.E., A.M. MACLEOD, A.Z. SNYDER, et al. 2001. A default mode of brain function. Proc. Natl. Acad. Sci. USA 98: 676-682.
33. KLUNK, W.E., H. ENGLER, A. NORDBERG, et al. 2004. Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound-B. Ann. Neurol. 55: 306-319.
34. MELTZER, C.C., J.K. ZUBIETA, J. BRANDT, et al. 1996. Regional hypometabolism in Alzheimer's disease as measured by positron emission tomography after correction for effects of partial volume averaging. Neurology 47: 454-461.
35. SILVERMAN, D.H., G.W. SMALL, C.Y. CHANG, et al. 2001. Positron emission tomography in evaluation of dementia: regional brain metabolism and long-term outcome. JAMA 286: 2120-2127.
36. ALEXANDER, G.E., K. CHEN, P. PIETRINI, et al. 2002. Longitudinal PET evaluation of cerebral metabolic decline in dementia: a potential outcome measure in Alzheimer's disease treatment studies. Am. J. Psychiatry 159: 738-745.
37. REIMAN, E.M., K. CHEN, G.E. ALEXANDER, et al. 2004. Functional brain abnormalities in young adults at genetic risk for late-onset Alzheimer's dementia. Proc. Natl. Acad. Sci. USA 101: 284-289.
38. SMALL, G.W., L.M. ERCOLI, D.H. SILVERMAN, et al. 2000. Cerebral metabolic and cognitive decline in persons at genetic risk for Alzheimer's disease. Proc. Natl. Acad. Sci. USA 97: 6037-6042.
39. JAGUST, W., A. GITCHO, F. SUN, et al. 2006. Brain imaging evidence of preclinical Alzheimer's disease in normal aging. Ann. Neurol. 59: 673-681.
40. ALSOP, D.C., J.A. DETRE & M. GROSSMAN. 2000. Assessment of cerebral blood flow in Alzheimer's disease by spin-labeled magnetic resonance imaging. Ann. Neurol. 47: 93-100.
41. JOHNSON, N.A., G.H. JAHNG, M.W. WEINER, et al. 2005. Pattern of cerebral hypoperfusion in Alzheimer disease and mild cognitive impairment measured with arterial spin-labeling MR imaging: initial experience. Radiology 234: 851-859.
42. CELONE, K., V. CALHOUN, B. DICKERSON, et al. 2006. Alterations in memory networks in mild cognitive impairment and Alzheimer's disease: an independent component analysis. J. Neuroscience. 26(40): 10222-10231.
43. BOOKHEIMER, S.Y., M.H. STROJWAS, M.S. COHEN, et al. 2000. Patterns of brain activation in people at risk for Alzheimer's disease. N. Engl. J. Med. 343: 450-456.
44. SMITH, C.D., A.H. ANDERSEN, R.J. KRYSCIO, et al. 2002. Women at risk for AD show increased parietal activation during a fluency task. Neurology 58: 1197-1202.
45. DICKERSON, B.C., D.H. SALAT, J.F. BATES, et al. 2004. Medial temporal lobe function and structure in mild cognitive impairment. Ann. Neurol. 56: 27-35.
46. JOHNSON, S.C., L.C. BAXTER, L. SUSSKIND- WILDER, et al. 2004. Hippocampal adaptation to face repetition in healthy elderly and mild cognitive impairment. Neuropsychologia 42: 980-989.
47. JOHNSON, S.C., T.W. SCHMITZ, C.H. MORITZ, et al. 2005. Activation of brain regions vulnerable to Alzheimer's disease: the effect of mild cognitive impairment. Neurobiol. Aging 27(11): 1604-1612.
48. BASSETT, S.S., D.M. YOUSEM, C. CRISTINZIO, et al. 2006. Familial risk for Alzheimer's disease alters fMRI activation patterns. Brain 129: 1229-1239.
49. MORRIS, J.C. 1993. The Clinical Dementia Rating (CDR): current version and scoring rules. Neurology 43: 2412-2414.