The human colon cancer methylome shows similar hypo- and hypermethylation at conserved tissue-specific CpG island shores

Nature Genetics

Volumn 41, Issue 2, 2009, Pages 178-186

  Irizarry, Rafael A ^a,b   Ladd Acosta, Christine ^b   Wen, Bo ^b   Wu, Zhijin ^c   Montano, Carolina ^b   Onyango, Patrick ^b   Cui, Hengmi ^b   Gabo, Kevin ^b   Rongione, Michael ^b   Webster, Maree ^d   Ji, Hong ^b   Potash, James B ^b   Sabunciyan, Sarven ^b   Feinberg, Andrew P ^b  

^a JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c BROWN UNIVERSITY   (United States)

^d UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA;

ANIMAL TISSUE; ARTICLE; CANCER MODEL; COLON; COLON CANCER; CONTROLLED STUDY; CPG ISLAND; DNA METHYLATION; EPIGENETICS; GENE EXPRESSION; GENE MUTATION; GENE SEQUENCE; GENETIC CONSERVATION; GENETIC MODEL; HUMAN; HUMAN CELL; HUMAN TISSUE; MOLECULAR MECHANICS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; ONCOGENE; PRIORITY JOURNAL; PROMOTER REGION; STEM CELL; TISSUE DIFFERENTIATION; TISSUE SPECIFICITY; TISSUE TYPES; TUMOR SUPPRESSOR GENE;

CARCINOMA; CHROMOSOME MAPPING; COLONIC NEOPLASMS; CONSERVED SEQUENCE; CPG ISLANDS; DNA METHYLATION; DNA MODIFICATION METHYLASES; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE SILENCING; GENOME, HUMAN; HCT116 CELLS; HUMANS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; ORGAN SPECIFICITY;

EID: 59149084538     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng.298     Document Type: Article

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