Multiple aspects of homocysteine neurotoxicity: Glutamate excitotoxicity, kinase hyperactivation and DNA damage

Journal of Neuroscience Research

Volumn 70, Issue 5, 2002, Pages 694-702

  Ho, Pei I ^a   Ortiz, Daniela ^a   Rogers, Eugene ^a   Shea, Thomas B ^a,b  

^a UNIVERSITY OF MASSACHUSETTS LOWELL   (United States)

^b University of Massachusetts Lowell   (United States)

Author keywords

Alzheimer's disease; Calcium influx; Excitotoxicity; Homocysteine; Oxidative stress; Tau phosphorylation

Indexed keywords

3 AMINOBENZAMIDE; ADENOSINE TRIPHOSPHATE; CALCIUM; CELL DNA; DIZOCILPINE; GLUTAMATE RECEPTOR; GLUTAMIC ACID; HOMOCYSTEINE; METABOTROPIC RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE INHIBITOR; PHOSPHATIDYLSERINE; REACTIVE OXYGEN METABOLITE; S ADENOSYLMETHIONINE; TAU PROTEIN;

ALZHEIMER DISEASE; ANIMAL CELL; APOPTOSIS; ARTICLE; BRAIN CELL; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL CULTURE; CHANNEL GATING; CONTROLLED STUDY; CYTOTOXICITY; DNA DAMAGE; DNA STRAND BREAKAGE; EMBRYO; HOMEOSTASIS; IMMUNOREACTIVITY; MOUSE; NERVE CELL EXCITABILITY; NEUROPATHOLOGY; NEUROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION;

ANIMALS; CALCIUM; CELLS, CULTURED; CEREBRAL CORTEX; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; GLUTAMIC ACID; HOMOCYSTEINE; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; NEURONS; NEUROTOXINS; OXIDATIVE STRESS; PHOSPHORYLATION; PROTEIN KINASES; RECEPTORS, N-METHYL-D-ASPARTATE; S-ADENOSYLMETHIONINE; TAU PROTEINS;

EID: 0036892748     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/jnr.10416     Document Type: Article

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