Curcumin inhibits formation of amyloid β oligomers and fibrils, binds plaques, and reduces amyloid in vivo

Journal of Biological Chemistry

Volumn 280, Issue 7, 2005, Pages 5892-5901

  Yang, Fusheng ^a,b   Lim, Giselle P ^a,b   Begum, Aynun N ^a,b   Ubeda, Oliver J ^a,b   Simmons, Mychica R ^a,b   Ambegaokar, Surendra S ^a,b   Chen, Pingping ^a,b   Kayed, Rakez ^d   Glabe, Charles G ^d   Frautschy, Salley A ^a,b,c   Cole, Gregory M ^a,b,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANTS; DISEASES; ENZYME INHIBITION; MOLECULAR STRUCTURE; STOICHIOMETRY;

ALZHEIMER'S DISEASE (AD); ANTIINFLAMMATORY CONSUMPTION; COGNITIVE DEFICITS;

OLIGOMERS;

AMYLOID BETA PROTEIN; CURCUMIN; IBUPROFEN; NAPROXEN; OLIGOMER;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; BLOOD BRAIN BARRIER; BRAIN; INFLAMMATION; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; STOICHIOMETRY;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BENZOATES; BIPHENYL COMPOUNDS; BLOOD-BRAIN BARRIER; BRAIN; CELL LINE, TUMOR; CONGO RED; CURCUMIN; DIAMINES; HUMANS; IBUPROFEN; MICE; MICE, TRANSGENIC; NAPROXEN; PEPTIDE FRAGMENTS; PROTEIN BINDING; PROTEIN DENATURATION; PROTEIN STRUCTURE, QUATERNARY; PYRIDAZINES; SENILE PLAQUES; SOLUBILITY; THIAZOLES;

ANIMALIA;

EID: 20044370990     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M404751200     Document Type: Article

References (63)

1. Selkoe, D. J. (1997) Science 275, 630-631
2. Pike, C. J., Walencewicz, A. J., Glabe, C. G., and Cotman, C. W. (1991) Brain Res. 563, 311-314
3. Klein, W. L., Krafft, G. A., and Finch, C. E. (2001) Trends Neurosci. 24, 219-224
4. Cummings, J. L., Vinters, H. V., Cole, G. M., and Khachaturian, Z. S. (1998) Neurology 51, S2-S17, S65-S67
5. Harris, M. E., Hensley, K., Butterfield, D. A., Leedle, R. A., and Carney, J. M. (1995) Exp. Neurol. 131, 1-10
6. Puchtler, H., Sweat, F., and Levine, M. (1962) J. Histochem. Cytochem. 10, 355-364
7. Lorenzo, A., and Yankner, B. A. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 12243-12247
8. Abe, K., Kato, M., and Saito, H. (1997) Neurosci. Res. 29, 129-134
9. Podlisny, M. B., Walsh, D. M., Amarante, P., Ostaszewski, B. L., Stimson, E. R., Maggio, J. E., Teplow, D. B., and Selkoe, D. J. (1998) Biochemistry 37, 3602-3611
10. Klunk, W. E., Debnath, M. L., and Pettegrew, J. W. (1994) Neurobiol. Aging 15, 691-698
11. Kelloff, G. J., Crowell, J. A., Hawk, E. T., Steele, V. E., Lubet, R. A., Boone, C. W., Covey, J. M., Doody, L. A., Omenn, G. S., Greenwald, P., Hong, W. K., Parkinson, D. R., Bagheri, D., Baxter, G. T., Blunden, M., Doeltz, M. K., Eisenhauer, K. M., Johnson, K., Knapp, G. G., Longfellow, D. G., Malone, W. F., Nayfield, S. G., Seifried, H. E., Swall, L. M., and Sigman, C. C. (1996) J. Cell. Biochem. Suppl. 26, 72-85
12. Lim, G. P., Chu, T., Yang, F., Beech, W., Frautschy, S. A., and Cole, G. M. (2001) J. Neurosci. 21, 8370-8377
13. Klunk, W. E., Jacob, R. F., and Mason, R. P. (1999) Anal. Biochem. 266, 66-76
14. Nakagami, Y., Nishimura, S., Murasugi, T., Kaneko, I., Meguro, M., Marumoto, S. K., H., Koyama, K., and Oda, T. (2002) Br. J. Pharamacol. 137, 676-682
15. Lim, G. P., Yang, F., Chu, T., Chen, P., Beech, W., Teter, B., Tran, T., Ubeda, O., Hsiao Ashe, K., Frautschy, S. A., and Cole, G. M. (2000) J. Neurosci. 20, 5709-5714
16. Calon, F., Lim, G. P., Yang, F., Morihara, T., Teter, B., Ubeda, O., Rostaing, P., Triller, A., Salem, N., Jr., Ashe, K. H., Frautschy, S. A., and Cole, G. M. (2004) Neuron 43, 633-645
17. Howlett, D. R., Perry, A. E., Godfrey, F., Swatton, J. E., Jennings, K. H., Spitzfaden, C., Wadsworth, H., Wood, S. J., and Markwell, R. E. (1999) Biochem. J. 340, 283-289
18. Chromy, B. A., Nowak, R. J., Lambert, M. P., Viola, K. L., Chang, L., Velasco, P. T., Jones, B. W., Fernandez, S. J., Lacor, P. N., Horowitz, P., Finch, C. E., Krafft, G. A., and Hein, W. L. (2003) Biochemistry 42, 12749-12760
19. Kayed, R., Head, E., Thompson, J. L., McIntire, T. M., Milton, S. C., Cotman, C. W., and Glabe, C. G. (2003) Science 300, 486-489
20. Yang, F., Sun, X., Beech, W., Teter, B., Wu, S., Sigel, J., Vinters, H. V., Frautschy, S. A., and Cole, G. M. (1998) Am. J. Pathol. 152, 379-389
21. Mosmann, T. (1983) J. Immunol. Methods 65, 55-63
22. Walsh, D. M., Klyubin, I., Fadeeva, J. V., Cullen, W. K., Anwyl, R., Wolfe, M. S., Rowan, M. J., and Selkoe, D. J. (2002) Nature 416, 535-539
23. Selkoe, D. J. (2002) Science 298, 789-791
24. Gong, Y., Chang, L., Viola, K. L., Lacor, P. N., Lambert, M. P., Finch, C. E., Krafft, G. A., and Klein, W. L. (2003) Proc. Natl. Acad. Sci. U. S. A. 100, 10417-10422
25. Lambert, M. P., Barlow, A. K., Chromy, B. A., Edwards, C., Freed, R., Liosatos, M., Morgan, T. E., Rozovsky, I., Trommer, B., Viola, K. L., Wals, P., Zhang, C., Finch, C. E., Krafft, G. A., and Klein, W. L. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 6448-6453
26. Das, P., Murphy, M. P., Younkin, L. H., Younkin, S. G., and Golde, T. E. (2001) Neurobiol. Aging 22, 721-727
27. Kawarabayashi, T., Younkin, L. H., Saido, T. C., Shoji, M., Hsiao-Ashe, K., and Younkin, S. G. (2001) J. Neurosci. 21, 372-381
28. in't Veld, B. A., Ruitenberg, A., Hofman, A., Launer, L. J., van Duijn, C. M., Stijnen, T., Breteler, M. M., and Stricker, B. H. (2001) N. Engl. J. Med. 345, 1515-1521
29. Etminan, M., Gill, S., and Samii, A. (2003) Br. Med. J. 327, 128
30. Launer, L. J. (2003) J. Am. Med. Assoc. 289, 2865-2867; Correction (2003) J. Am. Med. Assoc. 290, 1154
31. Landi, F., Cesari, M., Onder, G., Russo, A., Torre, S., and Bernabei, R. (2003) Am. J. Geriatr. Psychiatry 11, 179-185
32. Anthony, J. C., Breitner, J. C., Zandi, P. P., Meyer, M. R., Jurasova, I., Norton, M. C., and Stone, S. V. (2000) Neurology 54, 2066-2071
33. In't Veld, B. A., Launer, L. J., Hoes, A. W., Ott, A., Hofman, A., Breteler, M. M., and Stricker, B. H. (1998) Neurobiol. Aging 19, 607-611
34. Zandi, P. P., Anthony, J. C., Hayden, K. M., Mehta, K., Mayer, L., and Breitner, J. C. (2002) Neurology 59, 880-886
35. Weggen, S., Eriksen, J. L., Das, P., Sagi, S. A., Wang, R., Pietrzik, C. U., Findlay, K. A., Smith, T. E., Murphy, M. P., Bulter, T., Kang, D. E., Marquez-Sterling, N., Golde, T. E., and Koo, E. H. (2001) Nature 414, 212-216
36. Gasparini, L., Rusconi, L., Xu, H., del Soldato, P., and Ongini, E. (2004) J. Neurochem. 88, 337-348
37. Chun, K. S., Keum, Y. S., Han, S. S., Song, Y. S., Kim, S. H., and Surh, Y. J. (2003) Carcinogenesis 24, 1515-1524
38. Surh, Y. J., Chun, K. S., Cha, H. H., Han, S. S., Keum, Y. S., Park, K. K., and Lee, S. S. (2001) Mutat. Res. 480, 243-268
39. Plummer, S. M., Holloway, K. A., Manson, M. M., Munks, R. J., Kaptein, A., Farrow, S., and Howells, L. (1999) Oncogene 18, 6013-6020
40. Sagi, S. A., Weggen, S., Eriksen, J., Golde, T. E., and Koo, E. H. (2003) J. Biol. Chem. 278, 31825-31830
41. Frautschy, S. A., Hu, W., Miller, S. A., Kim, P., Harris-White, M. E., and Cole, G. M. (2001) Neurobiol. Aging 22, 991-1003
42. Agdeppa, E. D., Kepe, V., Petri, A., Satyamurthy, N., Liu, J., Huang, S. C., Small, G. W., Cole, G. M., and Barrio, J. R. (2002) Neuroscience 117, 723-730
43. Thomas, T., Nadackal, T. G., and Thomas, K. (2001) Neuroreport 12, 3263-3267
44. Liu, R., McAllister, C., Lyubchenko, Y., and Sierks, M. R. (2004) J. Neurosci. Res. 75, 162-171
45. Legleiter, J., Czilli, D. L., Gitter, B., DeMattos, R. B., Holtzman, D. M., and Kowalewski, T. (2004) J. Mol. Biol. 335, 997-1006
46. Pike, C. J., Walencewicz-Wasserman, A. J., Kosmoski, J., Cribbs, D. H., Glabe, C. G., and Cotman, C. W. (1995) J. Neurochem. 64, 253-265
47. Wang, J., Asensio, V. C., and Campbell, I. L. (2002) Curr. Top. Microbiol. Immunol. 265, 23-48
48. Chainani-Wu, N. (2003) J. Altern. Complement Med. 9, 161-168
49. Han, Y. S., Zheng, H., W., Bastianetto, S., Chabot, J. G., and Quirion, R. (2004) Br. J. Pharmacol. 141, 997-1005
50. Ritchie, C. W., Bush, A. I., Mackinnon, A., Macfarlane, S., Mastwyk, M., MacGregor, L., Kiers, L., Cherny, R., Li, Q. X., Tammer, A., Carrington, D., Mavros, C., Volitakis, I., Xilinas, M., Ames, D., Davis, S., Beyreuther, K., Tanzi, R. E., and Masters, C. L. (2003) Arch. Neurol. 60, 1685-1691
51. Cherny, R. A., Atwood, C. S., Xilinas, M. E., Gray, D. N., Jones, W. D., McLean, C. A., Barnham, K. J., Volitakis, I., Fraser, F. W., Kim, Y., Huang, X., Goldstein, L. E., Moir, R. D., Lim, J. T., Beyreuther, K., Zheng, H., Tanzi, R. E., Masters, C. L., and Bush, A. I. (2001) Neuron 30, 665-676
52. Atwood, C. S., Scarpa, R. C., Huang, X., Moir, R. D., Jones, W. D., Fairlie, D. P., Tanzi, R. E., and Bush, A. I. (2000) J. Neurochem. 75, 1219-1233
53. Baum, L., and Ng, A. (2004) J. Alzheimers Dis. 6, 367-377, 443-449
54. Ono, K., Hasegawa, K., Naiki, H., and Yamada, M. (2004) J. Neurosci. Res. 75, 742-750
55. Cheng, A. L., Hu, C. H., Lin, J. K., Hsu, M. M., Ho, Y. F., Shen, T. S., Ko, J. Y., Lin, J. T., Lin, B. R., Ming-Shiang, W., Yu, H. S., Jee, S. H., Chen, G. S., Chen, T. M., Chen, C. A., Lai, M. K., Pu, Y. S., Pan, M. H., Wang, Y. J., Tsai, C. C., and Hsieh, C. Y. (2001) Anticancer Res. 21, 2895-2900
56. Pan, M. H., Huang, T. M., and Lin, J. K. (1999) Drug Metab. Dispos. 27, 486-494
57. Cole, G. M., Yang, F., Lim, G. P., Cummings, J. L., Masterman, D. L., and Frautschy, S. A. (2003) Curr. Med. Chem. 3, 15-25
58. Luo, Y., Hattori, A., Munoz, J., Qin, Z., and Roth, G. (1999) Mol. Pharmacol. 56, 254-264
59. Chan, M. M., Huang, H. I., Fenton, M. R., and Fong, D. (1998) Biochem. Pharmacol. 55, 1955-1962
60. Zhao, B. L., Li, X. J., He, R. G., Cheng, S. J., and Xin, W. J. (1989) Cell Biophys. 14, 175-185
61. Soudamini, K. K., Unnikrishnan, M. C., Soni, K. B., and Kuttan, R. (1992) (1992) Indian J. Physiol. Pharmacol. 36, 239-243
62. Sreejayan, and Rao, M. N. A. (1994) J. Pharm. Pharmacol. 46, 1013-1016
63. Frautschy, S. A., Hammer, H., Hu, S., Hu, W., Oh, M., Miller, S. A., Lim, G. P., Harris-White, M. E., and Tenner, A. J. (2003) Soc. Neurosci. Abstr. 667.12