White matter changes in mild cognitive impairment and AD: A diffusion tensor imaging study

Neurobiology of Aging

Volumn 27, Issue 5, 2006, Pages 663-672

  Medina, David ^a   deToledo Morrell, Leyla ^a   Urresta, Fabio ^a   Gabrieli, John D E ^a,c   Moseley, Michael ^c   Fleischman, Debra ^a,b   Bennett, David A ^a,b   Leurgans, Sue ^a   Turner, David A ^a   Stebbins, Glenn T ^a  

^a RUSH UNIVERSITY MEDICAL CENTER   (United States)

^b RUSH UNIVERSITY MEDICAL CENTER   (United States)

^c STANFORD UNIVERSITY   (United States)

Author keywords

Aging; Cognition; Dementia; Fractional anisotropy; MRI

Indexed keywords

ADULT; AGED; ALZHEIMER DISEASE; AMNESIA; ANISOTROPY; ARTICLE; CALCULATION; CLINICAL ARTICLE; COGNITIVE DEFECT; COMPARATIVE STUDY; CONTROLLED STUDY; DEMENTIA; DIFFUSION TENSOR IMAGING; FEMALE; HUMAN; MALE; PRIORITY JOURNAL; RISK ASSESSMENT; WHITE MATTER;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; ANISOTROPY; BRAIN; COGNITION DISORDERS; DATA INTERPRETATION, STATISTICAL; DIFFUSION MAGNETIC RESONANCE IMAGING; FEMALE; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; INFARCTION, MIDDLE CEREBRAL ARTERY; MALE; MIDDLE AGED; PSYCHIATRIC STATUS RATING SCALES;

EID: 33646488698     PISSN: 01974580     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2005.03.026     Document Type: Article

References (74)

1. Arnold S.E., Hyman B.T., Flory J., Damasio A.R., and Van Hoesen G.W. The topographical and neuroanatomical distribution of neurofibrillary tangles and neuritic plaques in the cerebral cortex of patients with Alzheimer's disease. Cereb Cortex 1 (1991) 103-116
2. Barber R., Scheltens P., Gholkar A., Ballard C., McKeith I., Ince P., et al. White matter lesions on magnetic resonance imaging in dementia with Lewy bodies, Alzheimer's disease, vascular dementia, and normal aging. J Neurol Neurosurg Psychiatr 67 (1999) 66-72
3. Baron J.C., Chetelat G., Desgranges B., Perchey G., Landeau B., de la Sayette V., et al. In vivo mapping of gray mater loss with voxel-based morphometry in mild Alzheimer's disease. Neuroimage 14 (2001) 298-309
4. Bartzokis G. Age-related myelin breakdown: a developmental model of cognitive decline and Alzheimer's disease. Neurobiol Aging 25 (2004) 5-18
5. Bartzokis G., Cummings J.L., Sultzer D., Henderson V.W., Nuechterlein K.H., and Mintz J. White matter structural integrity in healthy aging adults and patients with Alzheimer's disease. Arch Neurol 60 (2003) 393-398
6. Bartzokis G., Sultzer D., Lu P.H., Nuechterlein K.H., Mintz J., and Cummings J.L. Heterogenous age related breakdown of white matter structural integrity: implications for cortical "disconnection" in aging and Alzheimer's disease. Neurobiol Aging 25 (2004) 843-851
7. Basser P.J. Inferring microstructural features and the physiological state of tissues from diffusion-weighted images. NMR Biomed 8 (1995) 333-344
8. Basser P.J., Matiello J., and Le Bihan D. Estimation of the effective self-diffusion tensor from the NMR spin echo. J Magn Reson B 103 (1994) 247-254
9. Basser P.J., and Pierpaoli C. Microstructural and physiological features of tissues elucidated by quantitative-diffusion-tensor MRI. J Magn Reson B 111 (1996) 209-219
10. Bennett D.A. Mild cognitive impairment. Clin Geriatr Med 20 (2004) 15-25
11. Bennett D.A., Wilson R.S., Schneider J.A., Evans D.A., Mendes de Leon C.F., Arnold S.E., et al. Education modifies the relation of AD pathology to level of cognitive function in older persons. Neurology 60 (2003) 1909-1915
12. Bigler E.D., Kerr B., Victoroff J., Tate D.F., and Breitner JC.S. White matter lesions, quantitative magnetic resonance imaging, and dementia. Alzheimer Dis Assoc Disord 16 (2002) 161-170
13. Bobinski M., de Leon M.J., Convit A., De Santi S., Wegiel J., Tarshish C.Y., et al. MRI of entorhinal cortex in mild Alzheimer's disease. Lancet 353 (1999) 38-40
14. Bowen J., Teri L., Kukull W., McCormick W., Mc Curry S.M., and Larson E.B. Progression to dementia in patients with isolated memory loss. Lancet 349 (1997) 763-765
15. Bozzali M., Falini A., Franceschi M., Cercignani M., Zuffi M., Scotti G., et al. White matter damage in Alzheimer's disease assessed in vivo using diffusion tensor magnetic resonance imaging. J Neurol Neurosurg Psychiatr 72 (2002) 742-746
16. Bozzao A., Floris R., Baviera M.E., Apruzzese A., and Simoneti G. Diffusion and perfusion MR imaging in cases of Alzheimer's disease: correlations with cortical atrophy and lesion load. Am J Neuroradiol 22 (2001) 1030-1036
17. Braak H., and Braak E. Staging of Alzheimer's disease-related neurofibrillary changes. Neurobiol Aging 16 (1995) 271-278
18. Bronge L., Bogdanovic N., and Wahlund L.O. Postmortem MRI and histopathology of white matter changes in Alzheimer brains. Dement Geriatr Cogn Disord 13 (2002) 205-212
19. Brun A., and Englund E. A white matter disorder in dementia of the Alzheimer type: a pathoanatomical study. Ann Neurol 19 (1986) 253-262
20. Busatto G.F., Garrido G.E.J., Almeida O.P., Castro C.C., Camargo C.H.P., Cid C.G., et al. A voxel-based morphometry study of temporal lobe gray matter reductions in Alzheimer's disease. Neurobiol Aging 24 (2003) 221-231
21. Callen D.J.A., Black S.E., Gao F., Caldwel C.B., and Szalai J.P. Beyond the hippocampus. MRI volumetry confirms widespread limbic atrophy in AD. Neurology 57 (2001) 1669-1674
22. Convit A., de Leon M.J., Tarshish C., De Santi S., Tsui W., Rusinek H., et al. Specific hippocampal volume reductions in individuals at risk for Alzheimer's disease. Neurobiol Aging 18 (1997) 131-138
23. Daly E., Zaitchik D., Copeland M., Schmahmann J., Gunther J., and Albert M. Predicting conversion to Alzheimer's disease using standardized clinical information. Arch Neurol 57 (2000) 675-680
24. DeCarli C., Miller B.L., Swan G.E., Reed T., Wolf P.A., and Carmelli D. Cerebrovascular and brain morphologic correlates of mild cognitive impairment in the National Heart, Lung, and Blood Institute Twin Study. Arch Neurol 58 (2001) 643-647
25. de Crespigny A.J., and Moseley M.E. Eddy current induced image warping in diffusion weighted EPI. Proceedings of the ISMRM sixth meeting. Sydney (1998) 661
26. deToledo-Morrell L., Goncharova I., Dickerson B., Wilson R.S., and Bennett D.A. From healthy aging to early Alzheimer's disease: in vivo detection of entorhinal cortex atrophy. Ann NY Acad Sci 911 (2000) 240-753
27. deToledo-Morrell L., Stoub T.R., Bulgakova M., Wilson R.S., Bennett D.A., Leurgans S., et al. MRI-derived entorhinal volume is a good predictor of conversion from MCI to AD. Neurobiol Aging 25 (2004) 1197-1203
28. deToledo-Morrell L., Sullivan M.P., Morrell F., Wilson R.S., Bennett D.A., and Spencer S. Alzheimer's disease: In vivo detection of differential vulnerability of brain regions. Neurobiol Aging 18 (1997) 438-463
29. Dickerson B.C., Goncharova I., Sullivan M.P., Forchetti C., Wilson R.S., Bennett D.A., et al. MRI-derived entorhinal and hippocampal atrophy in incipient and very mild Alzheimer's disease. Neurobiol Aging 22 (2001) 747-754
30. Du A.T., Schuff N., Amend D., Laakso M.P., Hsu Y.Y., Jagust W.J., et al. MRI of entorhinal cortex and hippocampus in mild cognitive impairment and Alzheimer's disease. J Neurol Neurosurg Psychiatr 71 (2001) 441-447
31. Englund E. Neuropathology of white matter changes in Alzheimer's disease and vascular dementia. Dement Geriatr Cogn Disord 9 Suppl. 1 (1998) 6-12
32. Fazekas F., Kapeller P., Schmidt R., Offenbacher H., Payer F., and Fazekas G. The relation of cerebral magnetic resonance signal hyperintensities to Alzheimer's disease. J Neurol Sci 142 (1996) 121-125
33. Fellgiebel A., Wille P., Muller M.J., Winterer G., Scheurich A., Vucurevic G., et al. Ultrastructural hippocampal and white matter alterations in mild cognitive impairment: a diffusion tensor imaging study. Dement Geriatr Cogn Disord 18 (2004) 101-108
34. Folstein M.F., Folstein S.E., and McHugh P.R. "Mini-mental state". A practical method for grading the mental status of patients for the clinician. J Psychiatr Res 12 (1975) 189-192
35. Friston K.J., Holmes A.P., Worsley K.J., Poline J.B., Frith J.D., and Frackowiak R.S. Statistical parametric maps in functional imaging: a general linear approach. Human Brain Map. 2 (1995) 189-210
36. Hanyu H., Asano T., Sakurai H., Imon Y., Iwamoto T., Takasake M., et al. Diffusion-weighted and magnetization transfer imaging of the corpus callosum in Alzheimer's disease. J Neurol Sci 167 (1999) 37-44
37. Hanyu H., Sakurai H., Iwamoto T., Takasaki M., Shindo H., and Abe K. Diffusion weighted MR imaging of the hippocampus and temporal white matter in Alzheimer's disease. J Neurol Sci 156 (1998) 195-200
38. Haselgrove J.C., and Moore J.R. Correction for distortion of echo-planar images used to calculate the apparent diffusion coefficient. Magn Reson Med 36 (1996) 960-964
39. Head D., Buckner R.L., Shimony J.S., Williams L.E., Akbudak E., Conturo T.E., et al. Differential vulnerability of anterior white matter in nondemented aging with minimal acceleration in dementia of the Alzheimer type: evidence from diffusion tensor imaging. Cereb Cortex 4 (2004) 410-423
40. Hirono N., Kitagaki H., Kazui H., Hashimoto M., and Mori E. Impact of white matter changes on clinical manifestation of Alzheimer's disease. Stroke 31 (2000) 2181-2188
41. Jack C.R., Petersen R.C., O'Brien P.C., and Tangalos E.G. MR-based hippocampal volumetry in the diagnosis of Alzheimer's disease. Neurology 42 (1992) 183-188
42. Jack C.R., Petersen R.C., Xu Y.C., Waring S.C., O'Brien P.C., Tangalos E.G., et al. Medial temporal atrophy on MRI in normal aging and very mild Alzheimer's disease. Neurology 49 (1997) 786-794
43. Jack C.R., Shiung M.M., Gunter J.L., O'Brien P.C., Weigand S.D., Knopman D.S., et al. Comparison of different MRI brain atrophy rate measures with clinical disease progression in AD. Neurology 62 (2004) 591-600
44. Kalaria R.N. The role of cerebral ischemia in Alzheimer's disease. Neurobiol Aging 21 (2000) 321-330
45. Kalaria R.N. Small vessel disease and Alzheimer's dementia: Pathological considerations. Cerebrovasc Dis 13 Suppl 2 (2002) 48-52
46. Kantarci K., Jack C.R., Xu Y.C., Campeau N.G., O'Brian P.C., Smith G.E., et al. Mild cognitive impairment and Alzheimer's disease: Regional diffusivity of water. Radiology 219 (2001) 101-107
47. Killiany R.J., Gomez-Isla T., Moss M., Kikinis R., Sandor T., Jolesz F., et al. Use of structural magnetic resonance imaging to predict who will get Alzheimer's disease. Ann Neurol 47 (2000) 430-439
48. Killiany R.J., Hyman B.T., Gomez-Isla T., Moss M.B., Kikinis R., Jolesz F., et al. MRI measures of entorhinal cortex vs hippocampus in preclinical AD. Neurology 58 (2002) 1188-1196
49. Kordower J.H., Chu Y., Stebbins G.T., DeKosky S.T., Cochran E.J., Bennett D.A., et al. Loss and atrophy of layer II entorhinal cortex neurons in elderly people with mild cognitive impairment. Ann Neurol 49 (2001) 202-213
50. Lancaster J.L., Woldorff M.G., Parsons L.M., Liotti M., Freitas C.S., Rainey L., et al. Automated Talairach Atlas labels for functional brain mapping. Human Brain Map. 10 (2000) 120-131
51. Lopez O.L., Becker J.T., Rezek D., Wess J., Boller F., Reynolds C.F., et al. Neuropsychiatric correlates of cerebral white-matter radiolucencies in probable Alzheimer's disease. Arch Neurol 49 (1992) 828-834
52. Makris N., Worth A.J., Sorenson A.G., Papadimitriou G.M., Wu O., Reese T.G., et al. Morphometry of in vivo human white matter association pathways with diffusion-weighted magnetic resonance imaging. Ann Neurol 42 (1997) 951-962
53. McKhann G., Drachman D., Folstein M., Katzman R., Price D., and Stadlan E.M. Clinical diagnosis of Alzheimer's disease: report of the NINCDS/ADRDA work group under the auspices of the Department of Health and Human Services Task Force on Alzheimer's disease. Neurology 34 (1984) 939-944
54. Mesulam M.-M. The cholinergic innervation of the human cerebral cortex. Prog Brain Res 145 (2004) 67-78
55. Mesulam M.-M., and Geula C. Nucleus basalis (Ch4) and cortical cholinergic innervation in the human brain: Observations based on the distribution of acetylcholinesterase and choline acetyltransferase. J Comp Neurol 275 (1988) 216-240
56. Minoshima S., Giordani B., Berent S., Frey K.A., Foster N.L., and Kuhl D.E. Metabolic reduction in the posterior cingulate cortex in very early Alzheimer's disease. Ann Neurol 42 (1997) 85-94
57. Morris J.C., Heyman A., Mohs R.C., van Belle G., Fillenbaum G., Mellits E.D., et al. The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part 1. Clinical and neuropsychological assessment of Alzheimer's disease. Neurology 39 (1989) 1159-1165
58. Mufson E.J., Chin E.Y., Cochran E.J., Beckett L.A., Bennett D.A., and Kordower J.H. Entorhinal cortex beta amyloid load in individuals with mild cognitive impairment. Exp Neurol 158 (1999) 469-490
59. Petersen R.C. Aging, mild cognitive impairment and Alzheimer's disease. Neurol Clin 18 (2000) 789-806
60. Petersen R.C., Doody R., Kurz A., Mohs R.C., Morris J.C., Rabins P.V., et al. Current concepts in mild cognitive impairment. Arch Neurol 58 (2001) 1985-1992
61. Petersen R.C., Smith G.E., Waring S.C., Ivnik R.J., Tangalos E.G., and Kokmen E. Mild cognitive impairment: clinical characterization and outcome. Arch Neurol 56 (1999) 303-308
62. Reiman E.M., Caselli R.J., Chen K., Alexander G.E., Bandy D., and Frost J. Declining brain activity in cognitively normal apolipoprotein E ε4 heterozygotes: a foundation for using positron emission tomography to efficiently test treatments to prevent Alzheimer's disease. Proc Natl Acad Sci USA 98 (2001) 334-3339
63. Reiman E.M., Caselli R.J., Yun L.S., Chen K., Bandy D., Minoshima S., et al. Preclinical evidence of Alzheimer's disease in persons homozygous for the epsilon 4 allele for apolipoprotein E. N Engl J Med 334 (1996) 752-758
64. Rose S.E., Chen F., Chalk J.B., Zelaya F.O., Strugnell W.E., Benson M., et al. Loss of connectivity in Alzheimer's disease: an evaluation of white matter tract integrity with color coded MR diffusion tensor imaging. J Neurol Neurosurg Psychiatr 69 (2000) 528-530
65. Sandon T.A., Felician O., Edelman R.R., and Warach S. Diffusion weighted magnetic resonance imaging in Alzheimer's disease. Dementia 10 (1999) 166-171
66. Selden N.R., Gitelman D.R., Salamon-Murayama N., Parrish T.B., and Mesulam M.M. Trajectories of cholinergic pathways within the cerebral hemispheres of the human brain. Brain 121 (1998) 2249-2257
67. Swartz R.H., Sahlas D.J., and Black S.E. Strategic involvement of cholinergic pathways and executive dysfunction: Does location of white matter signal hyperintensities matter?. J Stroke Cerebrovasc Dis 12 (2003) 29-36
68. Takahashi S., Yonezawa H., Takahashi J., Kudo M., Inoue T., and Toghi H. Selective reduction of diffusion anisotropy in white matter of Alzheimer's disease brains measured by 3.0 Tesla magnetic resonance imaging. Neurosci Lett 332 (2002) 45-48
69. Talairach J., and Tournoux P. Co-planar stereotaxic atlas of the human brain (1988), Thieme Medical Publishers, New York
70. Ulug A., Moore D.F., Bojko A.S., and Zimmerman R.D. Clinical use of diffusion-tensor imaging for diseases causing neuronal and axonal damage. Am J Neuroradiol 20 (1999) 1044-1048
71. Valla J., Berndt J.D., and Gonzalez-Lima F. Energy hypometabolism in posterior cingulate cortex of Alzheimer's patients: superficial laminar cytochrome oxidase associated with disease duration. J. Neurosci 13 (2001) 4923-4930
72. Wilson R.S., Sullivan M.P., deToledo-Morrell L., Stebbins G.T., Bennett D.A., and Morrell F. Association of memory and cognition in Alzheimer's disease with volumetric estimates of temporal lobe structures. Neuropsychology 10 (1996) 459-463
73. Xu Y., Jack C.R., O'Brien P.C., Kokmen E., Smith G.E., Ivnik R.J., et al. Usefulness of MRI measures of entorhinal cortex versus hippocampus in AD. Neurology 54 (2000) 1760-1767
74. Yoshiura T., Mihara F., Ogomori K., Tanaka A., Kaneko K., and Masuda K. Diffusion tensor in posterior cingulate gyrus: correlation with cognitive decline in Alzheimer's disease. Neuroreport 13 (2002) 2299-2302