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Volumn 38, Issue 11-12, 2003, Pages 1299-1307

The emerging role of epigenetics in cellular and organismal aging

Author keywords

Chromatin; Chromatin modifiers; DNA methylation; Histone acetylation; Histone methylation

Indexed keywords

ADENOSINE TRIPHOSPHATE; BETA GALACTOSIDASE; DNA METHYLTRANSFERASE; GENOMIC DNA; HISTONE ACETYLTRANSFERASE PCAF; HISTONE H3; HISTONE H4; PROTEIN P21; SILENT INFORMATION REGULATOR PROTEIN 2; TRANSCRIPTION FACTOR E2F1; TRANSCRIPTION FACTOR E2F4;

EID: 0346786306     PISSN: 05315565     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exger.2003.09.009     Document Type: Article
Times cited : (76)

References (101)
  • 2
    • 0025900189 scopus 로고
    • Modifiers of position effect are shared between telomeric and silent mating-type loci in S. cerevisiae
    • Aparicio O.M., Billington B.L., Gottschling D.E. Modifiers of position effect are shared between telomeric and silent mating-type loci in S. cerevisiae. Cell. 66:1991;1279-1287.
    • (1991) Cell , vol.66 , pp. 1279-1287
    • Aparicio, O.M.1    Billington, B.L.2    Gottschling, D.E.3
  • 3
    • 0035943709 scopus 로고    scopus 로고
    • Dnmt3a and Dnmt3b are transcriptional repressors that exhibit unique localization properties to heterochromatin
    • Bachman K.E., Rountree M.R., Baylin S.B. Dnmt3a and Dnmt3b are transcriptional repressors that exhibit unique localization properties to heterochromatin. J. Biol. Chem. 276:2001;32282-32287.
    • (2001) J. Biol. Chem. , vol.276 , pp. 32282-32287
    • Bachman, K.E.1    Rountree, M.R.2    Baylin, S.B.3
  • 4
    • 0036829085 scopus 로고    scopus 로고
    • Down-regulation of p300/CBP histone acetyltransferase activates a senescence checkpoint in human melanocytes
    • Bandyopadhyay D., Okan N.A., Bales E., Nascimento L., Cole P.A., Medrano E.E. Down-regulation of p300/CBP histone acetyltransferase activates a senescence checkpoint in human melanocytes. Cancer Res. 62:2002;6231-6239.
    • (2002) Cancer Res. , vol.62 , pp. 6231-6239
    • Bandyopadhyay, D.1    Okan, N.A.2    Bales, E.3    Nascimento, L.4    Cole, P.A.5    Medrano, E.E.6
  • 6
    • 0035801499 scopus 로고    scopus 로고
    • The chromatin remodelling factor Brg-1 interacts with beta-catenin to promote target gene activation
    • Barker N., Hurlstone A., Musisi H., Miles A., Bienz M., Clevers H. The chromatin remodelling factor Brg-1 interacts with beta-catenin to promote target gene activation. EMBO J. 20:2001;4935-4943.
    • (2001) EMBO J. , vol.20 , pp. 4935-4943
    • Barker, N.1    Hurlstone, A.2    Musisi, H.3    Miles, A.4    Bienz, M.5    Clevers, H.6
  • 8
    • 0034176798 scopus 로고    scopus 로고
    • DNA hypermethylation in tumorigenesis: Epigenetics joins genetics
    • Baylin S.B., Herman J.G. DNA hypermethylation in tumorigenesis: epigenetics joins genetics. Trends Genet. 16:2000;168-174.
    • (2000) Trends Genet. , vol.16 , pp. 168-174
    • Baylin, S.B.1    Herman, J.G.2
  • 9
    • 0036923370 scopus 로고    scopus 로고
    • Damage recovery pathways in Saccharomyces cerevisiae revealed by genomic phenotyping and interactome mapping
    • Begley T.J., Rosenbach A.S., Ideker T., Samson L.D. Damage recovery pathways in Saccharomyces cerevisiae revealed by genomic phenotyping and interactome mapping. Mol. Cancer Res. 1:2002;103-112.
    • (2002) Mol. Cancer Res. , vol.1 , pp. 103-112
    • Begley, T.J.1    Rosenbach, A.S.2    Ideker, T.3    Samson, L.D.4
  • 10
    • 0037129307 scopus 로고    scopus 로고
    • MeCP2 and MBD2 expression during normal and pathological growth of the human mammary gland
    • Billard L.M., Magdinier F., Lenoir G.M., Frappart L., Dante R. MeCP2 and MBD2 expression during normal and pathological growth of the human mammary gland. Oncogene. 21:2002;2704-2712.
    • (2002) Oncogene , vol.21 , pp. 2704-2712
    • Billard, L.M.1    Magdinier, F.2    Lenoir, G.M.3    Frappart, L.4    Dante, R.5
  • 11
    • 0034141972 scopus 로고    scopus 로고
    • CREB-binding protein and p300: Molecular integrators of hematopoietic transcription
    • Blobel G.A. CREB-binding protein and p300: molecular integrators of hematopoietic transcription. Blood. 95:2000;745-755.
    • (2000) Blood , vol.95 , pp. 745-755
    • Blobel, G.A.1
  • 12
    • 0036337759 scopus 로고    scopus 로고
    • Differentially methylated forms of histone H3 show unique association patterns with inactive human X chromosomes
    • Boggs B.A., Cheung P., Heard E., Spector D.L., Chinault A.C., Allis C.D. Differentially methylated forms of histone H3 show unique association patterns with inactive human X chromosomes. Nat. Genet. 30:2002;73-76.
    • (2002) Nat. Genet. , vol.30 , pp. 73-76
    • Boggs, B.A.1    Cheung, P.2    Heard, E.3    Spector, D.L.4    Chinault, A.C.5    Allis, C.D.6
  • 13
    • 0035059672 scopus 로고    scopus 로고
    • From cells to organisms: Can we learn about aging from cells in culture?
    • Campisi J. From cells to organisms: can we learn about aging from cells in culture? Exp. Gerontol. 36:2001;607-618.
    • (2001) Exp. Gerontol. , vol.36 , pp. 607-618
    • Campisi, J.1
  • 14
    • 0034916613 scopus 로고    scopus 로고
    • P300/CBP proteins: HATs for transcriptional bridges and scaffolds
    • Chan H.M., La Thangue N.B. p300/CBP proteins: HATs for transcriptional bridges and scaffolds. J. Cell Sci. 114:2001;2363-2373.
    • (2001) J. Cell Sci. , vol.114 , pp. 2363-2373
    • Chan, H.M.1    La Thangue, N.B.2
  • 15
    • 0036599352 scopus 로고    scopus 로고
    • Regulation of lifespan by histone deacetylase
    • Chang K.T., Min K.T. Regulation of lifespan by histone deacetylase. Ageing Res. Rev. 1:2002;313-326.
    • (2002) Ageing Res. Rev. , vol.1 , pp. 313-326
    • Chang, K.T.1    Min, K.T.2
  • 16
    • 0033636595 scopus 로고    scopus 로고
    • Synergistic coupling of histone H3 phosphorylation and acetylation in response to epidermal growth factor stimulation
    • Cheung P., Tanner K.G., Cheung W.L., Sassone-Corsi P., Denu J.M., Allis C.D. Synergistic coupling of histone H3 phosphorylation and acetylation in response to epidermal growth factor stimulation. Mol. Cell. 5:2000;905-915.
    • (2000) Mol. Cell , vol.5 , pp. 905-915
    • Cheung, P.1    Tanner, K.G.2    Cheung, W.L.3    Sassone-Corsi, P.4    Denu, J.M.5    Allis, C.D.6
  • 17
    • 0028239595 scopus 로고
    • Two human homologues of Saccharomyces cerevisiae SWI2/SNF2 and Drosophila brahma are transcriptional coactivators cooperating with the estrogen receptor and the retinoic acid receptor
    • Chiba H., Muramatsu M., Nomoto A., Kato H. Two human homologues of Saccharomyces cerevisiae SWI2/SNF2 and Drosophila brahma are transcriptional coactivators cooperating with the estrogen receptor and the retinoic acid receptor. Nucleic Acids Res. 22:1994;1815-1820.
    • (1994) Nucleic Acids Res. , vol.22 , pp. 1815-1820
    • Chiba, H.1    Muramatsu, M.2    Nomoto, A.3    Kato, H.4
  • 18
    • 0037221445 scopus 로고    scopus 로고
    • Linking chromatin function with metabolic networks: Sir2 family of NAD(+)-dependent deacetylases
    • Denu J.M. Linking chromatin function with metabolic networks: Sir2 family of NAD(+)-dependent deacetylases. Trends Biochem. Sci. 28:2003;41-48.
    • (2003) Trends Biochem. Sci. , vol.28 , pp. 41-48
    • Denu, J.M.1
  • 19
    • 0037405043 scopus 로고    scopus 로고
    • Role for human SIRT2 NAD-dependent deacetylase activity in control of mitotic exit in the cell cycle
    • Dryden S.C., Nahhas F.A., Nowak J.E., Goustin A.S., Tainsky M.A. Role for human SIRT2 NAD-dependent deacetylase activity in control of mitotic exit in the cell cycle. Mol. Cell Biol. 23:2003;3173-3185.
    • (2003) Mol. Cell Biol. , vol.23 , pp. 3173-3185
    • Dryden, S.C.1    Nahhas, F.A.2    Nowak, J.E.3    Goustin, A.S.4    Tainsky, M.A.5
  • 21
    • 0029157378 scopus 로고
    • Evolution of the SNF2 family of proteins: Subfamilies with distinct sequences and functions
    • Eisen J.A., Sweder K.S., Hanawalt P.C. Evolution of the SNF2 family of proteins: subfamilies with distinct sequences and functions. Nucleic Acids Res. 23:1995;2715-2723.
    • (1995) Nucleic Acids Res. , vol.23 , pp. 2715-2723
    • Eisen, J.A.1    Sweder, K.S.2    Hanawalt, P.C.3
  • 22
    • 0036182132 scopus 로고    scopus 로고
    • Precipitous release of methyl-CpG binding protein 2 and histone deacetylase 1 from the methylated human multidrug resistance gene (MDR1) on activation
    • El Osta A., Kantharidis P., Zalcberg J.R., Wolffe A.P. Precipitous release of methyl-CpG binding protein 2 and histone deacetylase 1 from the methylated human multidrug resistance gene (MDR1) on activation. Mol. Cell Biol. 22:2002;1844-1857.
    • (2002) Mol. Cell Biol. , vol.22 , pp. 1844-1857
    • El Osta, A.1    Kantharidis, P.2    Zalcberg, J.R.3    Wolffe, A.P.4
  • 23
    • 0023125009 scopus 로고
    • The in vitro lifespan of MRC-5 cells is shortened by 5-azacytidine- induced demethylation
    • Fairweather D.S., Fox M., Margison G.P. The in vitro lifespan of MRC-5 cells is shortened by 5-azacytidine-induced demethylation. Exp. Cell Res. 168:1987;153-159.
    • (1987) Exp. Cell Res. , vol.168 , pp. 153-159
    • Fairweather, D.S.1    Fox, M.2    Margison, G.P.3
  • 24
    • 0035312289 scopus 로고    scopus 로고
    • The MeCP1 complex represses transcription through preferential binding, remodeling, and deacetylating methylated nucleosomes
    • Feng Q., Zhang Y. The MeCP1 complex represses transcription through preferential binding, remodeling, and deacetylating methylated nucleosomes. Genes Dev. 15:2001;827-832.
    • (2001) Genes Dev. , vol.15 , pp. 827-832
    • Feng, Q.1    Zhang, Y.2
  • 25
    • 0030831573 scopus 로고    scopus 로고
    • Direct evidence for SIR2 modulation of chromatin structure in yeast rDNA
    • Fritze C.E., Verschueren K., Strich R., Easton E.R. Direct evidence for SIR2 modulation of chromatin structure in yeast rDNA. EMBO J. 16:1997;6495-6509.
    • (1997) EMBO J. , vol.16 , pp. 6495-6509
    • Fritze, C.E.1    Verschueren, K.2    Strich, R.3    Easton, E.R.4
  • 26
    • 0038412822 scopus 로고    scopus 로고
    • The DNA methyltransferases associate with HP1 and the SUV39H1 histone methyltransferase
    • Fuks F., Hurd P.J., Deplus R., Kouzarides T. The DNA methyltransferases associate with HP1 and the SUV39H1 histone methyltransferase. Nucleic Acids Res. 31:2003;2305-2312.
    • (2003) Nucleic Acids Res. , vol.31 , pp. 2305-2312
    • Fuks, F.1    Hurd, P.J.2    Deplus, R.3    Kouzarides, T.4
  • 28
    • 0034193776 scopus 로고    scopus 로고
    • Sir2 links chromatin silencing, metabolism, and aging
    • Guarente L. Sir2 links chromatin silencing, metabolism, and aging. Genes Dev. 14:2000;1021-1026.
    • (2000) Genes Dev. , vol.14 , pp. 1021-1026
    • Guarente, L.1
  • 30
    • 0037470539 scopus 로고    scopus 로고
    • Genetics and the specificity of the aging process
    • Hekimi S., Guarente L. Genetics and the specificity of the aging process. Science. 299:2003;1351-1354.
    • (2003) Science , vol.299 , pp. 1351-1354
    • Hekimi, S.1    Guarente, L.2
  • 31
    • 0024802174 scopus 로고
    • Age-related methylation changes in DNA may reflect the proliferative potential of organs
    • Hoal-van Helden E.G., van Helden P.D. Age-related methylation changes in DNA may reflect the proliferative potential of organs. Mutat. Res. 219:1989;263-266.
    • (1989) Mutat. Res. , vol.219 , pp. 263-266
    • Hoal-Van Helden, E.G.1    Van Helden, P.D.2
  • 32
    • 0026579251 scopus 로고
    • Demethylation of satellite I DNA during senescence of bovine adrenocortical cells in culture
    • Hornsby P.J., Yang L., Gunter L.E. Demethylation of satellite I DNA during senescence of bovine adrenocortical cells in culture. Mutat. Res. 275:1992;13-19.
    • (1992) Mutat. Res. , vol.275 , pp. 13-19
    • Hornsby, P.J.1    Yang, L.2    Gunter, L.E.3
  • 33
    • 0029935604 scopus 로고    scopus 로고
    • Replicative senescence: Considerations relating to the stability of heterochromatin domains
    • Howard B.H. Replicative senescence: considerations relating to the stability of heterochromatin domains. Exp. Gerontol. 31:1996;281-293.
    • (1996) Exp. Gerontol. , vol.31 , pp. 281-293
    • Howard, B.H.1
  • 34
    • 0038064220 scopus 로고    scopus 로고
    • Aging reduces proliferative capacities of liver by switching pathways of C/EBPalpha growth arrest
    • Iakova P., Awad S.S., Timchenko N.A. Aging reduces proliferative capacities of liver by switching pathways of C/EBPalpha growth arrest. Cell. 113:2003;495-506.
    • (2003) Cell , vol.113 , pp. 495-506
    • Iakova, P.1    Awad, S.S.2    Timchenko, N.A.3
  • 35
    • 0034677535 scopus 로고    scopus 로고
    • Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase
    • Imai S., Armstrong C.M., Kaeberlein M., Guarente L. Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase. Nature. 403:2000;795-800.
    • (2000) Nature , vol.403 , pp. 795-800
    • Imai, S.1    Armstrong, C.M.2    Kaeberlein, M.3    Guarente, L.4
  • 36
    • 0036324919 scopus 로고    scopus 로고
    • Epigenetic variation and human disease
    • Issa J.P. Epigenetic variation and human disease. J. Nutr. 132:2002;2388S-2392S.
    • (2002) J. Nutr. , vol.132
    • Issa, J.P.1
  • 37
    • 0037372003 scopus 로고    scopus 로고
    • Epigenetic regulation of gene expression: How the genome integrates intrinsic and environmental signals
    • Jaenisch R., Bird A. Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals. Nat. Genet. 33:(Suppl.):2003;245-254.
    • (2003) Nat. Genet. , vol.33 , Issue.SUPPL. , pp. 245-254
    • Jaenisch, R.1    Bird, A.2
  • 38
    • 0035839136 scopus 로고    scopus 로고
    • Translating the histone code
    • Jenuwein T., Allis C.D. Translating the histone code. Science. 293:2001;1074-1080.
    • (2001) Science , vol.293 , pp. 1074-1080
    • Jenuwein, T.1    Allis, C.D.2
  • 39
    • 0036274359 scopus 로고    scopus 로고
    • The fundamental role of epigenetic events in cancer
    • Jones P.A., Baylin S.B. The fundamental role of epigenetic events in cancer. Nat. Rev. Genet. 3:2002;415-428.
    • (2002) Nat. Rev. Genet. , vol.3 , pp. 415-428
    • Jones, P.A.1    Baylin, S.B.2
  • 40
    • 0032960181 scopus 로고    scopus 로고
    • Cancer epigenetics comes of age
    • Jones P.A., Laird P.W. Cancer epigenetics comes of age. Nat. Genet. 21:1999;163-167.
    • (1999) Nat. Genet. , vol.21 , pp. 163-167
    • Jones, P.A.1    Laird, P.W.2
  • 42
    • 0033214237 scopus 로고    scopus 로고
    • The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms
    • Kaeberlein M., McVey M., Guarente L. The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms. Genes Dev. 13:1999;2570-2580.
    • (1999) Genes Dev. , vol.13 , pp. 2570-2580
    • Kaeberlein, M.1    McVey, M.2    Guarente, L.3
  • 43
  • 44
    • 0027493251 scopus 로고
    • BRG1 contains a conserved domain of the SWI2/SNF2 family necessary for normal mitotic growth and transcription
    • Khavari P.A., Peterson C.L., Tamkun J.W., Mendel D.B., Crabtree G.R. BRG1 contains a conserved domain of the SWI2/SNF2 family necessary for normal mitotic growth and transcription. Nature. 366:1993;170-174.
    • (1993) Nature , vol.366 , pp. 170-174
    • Khavari, P.A.1    Peterson, C.L.2    Tamkun, J.W.3    Mendel, D.B.4    Crabtree, G.R.5
  • 45
    • 0035282573 scopus 로고    scopus 로고
    • Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins
    • Lachner M., O'Carroll D., Rea S., Mechtler K., Jenuwein T. Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins. Nature. 410:2001;116-120.
    • (2001) Nature , vol.410 , pp. 116-120
    • Lachner, M.1    O'Carroll, D.2    Rea, S.3    Mechtler, K.4    Jenuwein, T.5
  • 48
    • 0027465862 scopus 로고
    • A positive role for histone acetylation in transcription factor access to nucleosomal DNA
    • Lee D.Y., Hayes J.J., Pruss D., Wolffe A.P. A positive role for histone acetylation in transcription factor access to nucleosomal DNA. Cell. 72:1993;73-84.
    • (1993) Cell , vol.72 , pp. 73-84
    • Lee, D.Y.1    Hayes, J.J.2    Pruss, D.3    Wolffe, A.P.4
  • 49
    • 0037453509 scopus 로고    scopus 로고
    • Cancer. An unstable liaison
    • Lengauer C. Cancer. An unstable liaison. Science. 300:2003;442-443.
    • (2003) Science , vol.300 , pp. 442-443
    • Lengauer, C.1
  • 50
    • 0036194173 scopus 로고    scopus 로고
    • Histone acetyltransferase activities of cAMP regulated enhancer-binding protein and p300 in tissues of fetal, young, and old mice
    • Li Q., Xiao H., Isobe K. Histone acetyltransferase activities of cAMP regulated enhancer-binding protein and p300 in tissues of fetal, young, and old mice. J. Gerontol. A Biol. Sci. Med. Sci. 57:2002;B93-B98.
    • (2002) J. Gerontol. a Biol. Sci. Med. Sci. , vol.57
    • Li, Q.1    Xiao, H.2    Isobe, K.3
  • 51
    • 0037376665 scopus 로고    scopus 로고
    • Nicotinamide adenine dinucleotide, a metabolic regulator of transcription, longevity and disease
    • Lin S.J., Guarente L. Nicotinamide adenine dinucleotide, a metabolic regulator of transcription, longevity and disease. Curr. Opin. Cell Biol. 15:2003;241-246.
    • (2003) Curr. Opin. Cell Biol. , vol.15 , pp. 241-246
    • Lin, S.J.1    Guarente, L.2
  • 53
    • 0033638105 scopus 로고    scopus 로고
    • Phosphorylation of serine 10 in histone H3 is functionally linked in vitro and in vivo to Gcn5-mediated acetylation at lysine 14
    • Lo W.S., Trievel R.C., Rojas J.R., Duggan L., Hsu J.Y., Allis C.D., Marmorstein R., Berger S.L. Phosphorylation of serine 10 in histone H3 is functionally linked in vitro and in vivo to Gcn5-mediated acetylation at lysine 14. Mol. Cell. 5:2000;917-926.
    • (2000) Mol. Cell , vol.5 , pp. 917-926
    • Lo, W.S.1    Trievel, R.C.2    Rojas, J.R.3    Duggan, L.4    Hsu, J.Y.5    Allis, C.D.6    Marmorstein, R.7    Berger, S.L.8
  • 54
    • 1842411320 scopus 로고    scopus 로고
    • Crystal structure of the nucleosome core particle at 2.8 Å resolution
    • Luger K., Mader A.W., Richmond R.K., Sargent D.F., Richmond T.J. Crystal structure of the nucleosome core particle at 2.8 Å resolution. Nature. 389:1997;251-260.
    • (1997) Nature , vol.389 , pp. 251-260
    • Luger, K.1    Mader, A.W.2    Richmond, R.K.3    Sargent, D.F.4    Richmond, T.J.5
  • 55
    • 0032549001 scopus 로고    scopus 로고
    • Rb interacts with histone deacetylase to repress transcription
    • Luo R.X., Postigo A.A., Dean D.C. Rb interacts with histone deacetylase to repress transcription. Cell. 92:1998;463-473.
    • (1998) Cell , vol.92 , pp. 463-473
    • Luo, R.X.1    Postigo, A.A.2    Dean, D.C.3
  • 56
    • 0018858640 scopus 로고
    • Implications of the reorganization of the cell genome for aging or immortalization of dividing cells in vitro
    • Macieira-Coelho A. Implications of the reorganization of the cell genome for aging or immortalization of dividing cells in vitro. Gerontology. 26:1980;276-282.
    • (1980) Gerontology , vol.26 , pp. 276-282
    • MacIeira-Coelho, A.1
  • 58
    • 0033535957 scopus 로고    scopus 로고
    • The Rpd3 histone deacetylase is required for segmentation of the Drosophila embryo
    • Mannervik M., Levine M. The Rpd3 histone deacetylase is required for segmentation of the Drosophila embryo. Proc. Natl Acad. Sci. USA. 96:1999;6797-6801.
    • (1999) Proc. Natl Acad. Sci. USA , vol.96 , pp. 6797-6801
    • Mannervik, M.1    Levine, M.2
  • 61
    • 0037067798 scopus 로고    scopus 로고
    • Age-related changes in nuclear receptor coactivator immunoreactivity in motoneurons of the spinal nucleus of the bulbocavernosus of male rats
    • Matsumoto A. Age-related changes in nuclear receptor coactivator immunoreactivity in motoneurons of the spinal nucleus of the bulbocavernosus of male rats. Brain Res. 943:2002;202-205.
    • (2002) Brain Res. , vol.943 , pp. 202-205
    • Matsumoto, A.1
  • 62
    • 0037359584 scopus 로고    scopus 로고
    • The absence of SIR2alpha protein has no effect on global gene silencing in mouse embryonic stem cells
    • McBurney M.W., Yang X., Jardine K., Bieman M., Th'ng J., Lemieux M. The absence of SIR2alpha protein has no effect on global gene silencing in mouse embryonic stem cells. Mol. Cancer Res. 1:2003;402-409.
    • (2003) Mol. Cancer Res. , vol.1 , pp. 402-409
    • McBurney, M.W.1    Yang, X.2    Jardine, K.3    Bieman, M.4    Th'Ng, J.5    Lemieux, M.6
  • 63
    • 0027434083 scopus 로고
    • A human homologue of Saccharomyces cerevisiae SNF2/SWI2 and Drosophila brm genes potentiates transcriptional activation by the glucocorticoid receptor
    • Muchardt C., Yaniv M. A human homologue of Saccharomyces cerevisiae SNF2/SWI2 and Drosophila brm genes potentiates transcriptional activation by the glucocorticoid receptor. EMBO J. 12:1993;4279-4290.
    • (1993) EMBO J. , vol.12 , pp. 4279-4290
    • Muchardt, C.1    Yaniv, M.2
  • 64
    • 0032574977 scopus 로고    scopus 로고
    • Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex
    • Nan X., Ng H.H., Johnson C.A., Laherty C.D., Turner B.M., Eisenman R.N., Bird A. Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex. Nature. 393:1998;386-389.
    • (1998) Nature , vol.393 , pp. 386-389
    • Nan, X.1    Ng, H.H.2    Johnson, C.A.3    Laherty, C.D.4    Turner, B.M.5    Eisenman, R.N.6    Bird, A.7
  • 69
    • 0029778901 scopus 로고    scopus 로고
    • Human fibroblast commitment to a senescence-like state in response to histone deacetylase inhibitors is cell cycle dependent
    • Ogryzko V.V., Hirai T.H., Russanova V.R., Barbie D.A., Howard B.H. Human fibroblast commitment to a senescence-like state in response to histone deacetylase inhibitors is cell cycle dependent. Mol. Cell Biol. 16:1996;5210-5218.
    • (1996) Mol. Cell Biol. , vol.16 , pp. 5210-5218
    • Ogryzko, V.V.1    Hirai, T.H.2    Russanova, V.R.3    Barbie, D.A.4    Howard, B.H.5
  • 72
    • 0032403109 scopus 로고    scopus 로고
    • Altered control of cellular proliferation in the absence of mammalian brahma (SNF2alpha)
    • Reyes J.C., Barra J., Muchardt C., Camus A., Babinet C., Yaniv M. Altered control of cellular proliferation in the absence of mammalian brahma (SNF2alpha). EMBO J. 17:1998;6979-6991.
    • (1998) EMBO J. , vol.17 , pp. 6979-6991
    • Reyes, J.C.1    Barra, J.2    Muchardt, C.3    Camus, A.4    Babinet, C.5    Yaniv, M.6
  • 73
    • 0037086656 scopus 로고    scopus 로고
    • In vivo repression of an erythroid-specific gene by distinct corepressor complexes
    • Rietveld L.E., Caldenhoven E., Stunnenberg H.G. In vivo repression of an erythroid-specific gene by distinct corepressor complexes. EMBO J. 21:2002;1389-1397.
    • (2002) EMBO J. , vol.21 , pp. 1389-1397
    • Rietveld, L.E.1    Caldenhoven, E.2    Stunnenberg, H.G.3
  • 74
    • 18744416824 scopus 로고    scopus 로고
    • Longevity regulation by Drosophila Rpd3 deacetylase and caloric restriction
    • Rogina B., Helfand S.L., Frankel S. Longevity regulation by Drosophila Rpd3 deacetylase and caloric restriction. Science. 298:2002;1745-1745.
    • (2002) Science , vol.298 , pp. 1745-1745
    • Rogina, B.1    Helfand, S.L.2    Frankel, S.3
  • 75
    • 0037131426 scopus 로고    scopus 로고
    • Postsynthetic trimethylation of histone H4 at lysine 20 in mammalian tissues is associated with aging
    • Sarg B., Koutzamani E., Helliger W., Rundquist I., Lindner H.H. Postsynthetic trimethylation of histone H4 at lysine 20 in mammalian tissues is associated with aging. J. Biol. Chem. 277:2002;39195-39201.
    • (2002) J. Biol. Chem. , vol.277 , pp. 39195-39201
    • Sarg, B.1    Koutzamani, E.2    Helliger, W.3    Rundquist, I.4    Lindner, H.H.5
  • 76
    • 0032929628 scopus 로고    scopus 로고
    • Cyclin e associates with BAF155 and BRG1, components of the mammalian SWI-SNF complex, and alters the ability of BRG1 to induce growth arrest
    • Shanahan F., Seghezzi W., Parry D., Mahony D., Lees E. Cyclin E associates with BAF155 and BRG1, components of the mammalian SWI-SNF complex, and alters the ability of BRG1 to induce growth arrest. Mol. Cell Biol. 19:1999;1460-1469.
    • (1999) Mol. Cell Biol. , vol.19 , pp. 1460-1469
    • Shanahan, F.1    Seghezzi, W.2    Parry, D.3    Mahony, D.4    Lees, E.5
  • 77
    • 0037198057 scopus 로고    scopus 로고
    • Paradigms and pitfalls of yeast longevity research
    • Sinclair D.A. Paradigms and pitfalls of yeast longevity research. Mech. Ageing Dev. 123:2002;857-867.
    • (2002) Mech. Ageing Dev. , vol.123 , pp. 857-867
    • Sinclair, D.A.1
  • 78
    • 0028986413 scopus 로고
    • A role for retinoblastoma protein in potentiating transcriptional activation by the glucocorticoid receptor
    • Singh P., Coe J., Hong W. A role for retinoblastoma protein in potentiating transcriptional activation by the glucocorticoid receptor. Nature. 374:1995;562-565.
    • (1995) Nature , vol.374 , pp. 562-565
    • Singh, P.1    Coe, J.2    Hong, W.3
  • 80
    • 0031172243 scopus 로고    scopus 로고
    • Cell growth inhibition by the Mad/Max complex through recruitment of histone deacetylase activity
    • Sommer A., Hilfenhaus S., Menkel A., Kremmer E., Seiser C., Loidl P., Luscher B. Cell growth inhibition by the Mad/Max complex through recruitment of histone deacetylase activity. Curr. Biol. 7:1997;357-365.
    • (1997) Curr. Biol. , vol.7 , pp. 357-365
    • Sommer, A.1    Hilfenhaus, S.2    Menkel, A.3    Kremmer, E.4    Seiser, C.5    Loidl, P.6    Luscher, B.7
  • 81
    • 0031027431 scopus 로고    scopus 로고
    • SIR2 and SIR4 interactions differ in core and extended telomeric heterochromatin in yeast
    • Strahl-Bolsinger S., Hecht A., Luo K., Grunstein M. SIR2 and SIR4 interactions differ in core and extended telomeric heterochromatin in yeast. Genes Dev. 11:1997;83-93.
    • (1997) Genes Dev. , vol.11 , pp. 83-93
    • Strahl-Bolsinger, S.1    Hecht, A.2    Luo, K.3    Grunstein, M.4
  • 84
    • 0032578762 scopus 로고    scopus 로고
    • Chromatin deacetylation by an ATP-dependent nucleosome remodelling complex
    • Tong J.K., Hassig C.A., Schnitzler G.R., Kingston R.E., Schreiber S.L. Chromatin deacetylation by an ATP-dependent nucleosome remodelling complex. Nature. 395:1998;917-921.
    • (1998) Nature , vol.395 , pp. 917-921
    • Tong, J.K.1    Hassig, C.A.2    Schnitzler, G.R.3    Kingston, R.E.4    Schreiber, S.L.5
  • 86
    • 0032514742 scopus 로고    scopus 로고
    • Enhanced transcription factor access to arrays of histone H3/H4 tetramer DNA complexes in vitro: Implications for replication and transcription
    • Tse C., Fletcher T.M., Hansen J.C. Enhanced transcription factor access to arrays of histone H3/H4 tetramer DNA complexes in vitro: implications for replication and transcription. Proc. Natl Acad. Sci. USA. 95:1998;12169-12173.
    • (1998) Proc. Natl Acad. Sci. USA , vol.95 , pp. 12169-12173
    • Tse, C.1    Fletcher, T.M.2    Hansen, J.C.3
  • 87
    • 0025779831 scopus 로고
    • Histone acetylation and control of gene expression
    • Turner B.M. Histone acetylation and control of gene expression. J. Cell Sci. 99:(Pt 1):1991;13-20.
    • (1991) J. Cell Sci. , vol.99 , Issue.PT 1 , pp. 13-20
    • Turner, B.M.1
  • 88
    • 0030998534 scopus 로고    scopus 로고
    • Histone acetylation: Influence on transcription, nucleosome mobility and positioning, and linker histone-dependent transcriptional repression
    • Ura K., Kurumizaka H., Dimitrov S., Almouzni G., Wolffe A.P. Histone acetylation: influence on transcription, nucleosome mobility and positioning, and linker histone-dependent transcriptional repression. EMBO J. 16:1997;2096-2107.
    • (1997) EMBO J. , vol.16 , pp. 2096-2107
    • Ura, K.1    Kurumizaka, H.2    Dimitrov, S.3    Almouzni, G.4    Wolffe, A.P.5
  • 89
    • 0037354608 scopus 로고    scopus 로고
    • Chromatin as a tool for the study of genome function in cancer
    • Urnov F.D. Chromatin as a tool for the study of genome function in cancer. Ann. N.Y. Acad. Sci. 983:2003;5-21.
    • (2003) Ann. N.Y. Acad. Sci. , vol.983 , pp. 5-21
    • Urnov, F.D.1
  • 91
    • 0028080422 scopus 로고
    • Stabilization of DNA methyltransferase levels and CpG island hypermethylation precede SV40-induced immortalization of human fibroblasts
    • Vertino P.M., Issa J.P., Pereira-Smith O.M., Baylin S.B. Stabilization of DNA methyltransferase levels and CpG island hypermethylation precede SV40-induced immortalization of human fibroblasts. Cell Growth Differ. 5:1994;1395-1402.
    • (1994) Cell Growth Differ. , vol.5 , pp. 1395-1402
    • Vertino, P.M.1    Issa, J.P.2    Pereira-Smith, O.M.3    Baylin, S.B.4
  • 94
    • 0020638422 scopus 로고
    • DNA methylation decreases in aging but not in immortal cells
    • Wilson V.L., Jones P.A. DNA methylation decreases in aging but not in immortal cells. Science. 220:1983;1055-1057.
    • (1983) Science , vol.220 , pp. 1055-1057
    • Wilson, V.L.1    Jones, P.A.2
  • 95
    • 0031577480 scopus 로고    scopus 로고
    • Sodium butyrate induces NIH3T3 cells to senescence-like state and enhances promoter activity of p21WAF/CIP1 in p53-independent manner
    • Xiao H., Hasegawa T., Miyaishi O., Ohkusu K., Isobe K. Sodium butyrate induces NIH3T3 cells to senescence-like state and enhances promoter activity of p21WAF/CIP1 in p53-independent manner. Biochem. Biophys. Res. Commun. 237:1997;457-460.
    • (1997) Biochem. Biophys. Res. Commun. , vol.237 , pp. 457-460
    • Xiao, H.1    Hasegawa, T.2    Miyaishi, O.3    Ohkusu, K.4    Isobe, K.5
  • 96
    • 0032252209 scopus 로고    scopus 로고
    • NURD, a novel complex with both ATP-dependent chromatin-remodeling and histone deacetylase activities
    • Xue Y., Wong J., Moreno G.T., Young M.K., Cote J., Wang W. NURD, a novel complex with both ATP-dependent chromatin-remodeling and histone deacetylase activities. Mol. Cell. 2:1998;851-861.
    • (1998) Mol. Cell , vol.2 , pp. 851-861
    • Xue, Y.1    Wong, J.2    Moreno, G.T.3    Young, M.K.4    Cote, J.5    Wang, W.6
  • 97
    • 17644445419 scopus 로고    scopus 로고
    • Gene dosage-dependent embryonic development and proliferation defects in mice lacking the transcriptional integrator p300
    • Yao T.P., Oh S.P., Fuchs M., Zhou N.D., Ch'ng L.E., Newsome D., Bronson R.T., Li E., Livingston D.M., Eckner R. Gene dosage-dependent embryonic development and proliferation defects in mice lacking the transcriptional integrator p300. Cell. 93:1998;361-372.
    • (1998) Cell , vol.93 , pp. 361-372
    • Yao, T.P.1    Oh, S.P.2    Fuchs, M.3    Zhou, N.D.4    Ch'Ng, L.E.5    Newsome, D.6    Bronson, R.T.7    Li, E.8    Livingston, D.M.9    Eckner, R.10
  • 98
    • 0035374458 scopus 로고
    • DNA methyltransferase inhibition in normal human fibroblasts induces a p21-dependent cell cycle withdrawal
    • Young J.I., Smith J.R. DNA methyltransferase inhibition in normal human fibroblasts induces a p21-dependent cell cycle withdrawal. J. Biol. Chem. 276:1961;19610-19616.
    • (1961) J. Biol. Chem. , vol.276 , pp. 19610-19616
    • Young, J.I.1    Smith, J.R.2
  • 99
    • 0032538293 scopus 로고    scopus 로고
    • The dermatomyositis-specific autoantigen Mi2 is a component of a complex containing histone deacetylase and nucleosome remodeling activities
    • Zhang Y., LeRoy G., Seelig H.P., Lane W.S., Reinberg D. The dermatomyositis-specific autoantigen Mi2 is a component of a complex containing histone deacetylase and nucleosome remodeling activities. Cell. 95:1998;279-289.
    • (1998) Cell , vol.95 , pp. 279-289
    • Zhang, Y.1    Leroy, G.2    Seelig, H.P.3    Lane, W.S.4    Reinberg, D.5
  • 100
    • 0034737290 scopus 로고    scopus 로고
    • Exit from G1 and S phase of the cell cycle is regulated by repressor complexes containing HDAC-Rb-hSWI/SNF and Rb-hSWI/SNF
    • Zhang H.S., Gavin M., Dahiya A., Postigo A.A., Ma D., Luo R.X., Harbour J.W., Dean D.C. Exit from G1 and S phase of the cell cycle is regulated by repressor complexes containing HDAC-Rb-hSWI/SNF and Rb-hSWI/SNF. Cell. 101:2000;79-89.
    • (2000) Cell , vol.101 , pp. 79-89
    • Zhang, H.S.1    Gavin, M.2    Dahiya, A.3    Postigo, A.A.4    Ma, D.5    Luo, R.X.6    Harbour, J.W.7    Dean, D.C.8
  • 101
    • 0037452888 scopus 로고    scopus 로고
    • Senescence-specific gene expression fingerprints reveal cell-type-dependent physical clustering of up-regulated chromosomal loci
    • Zhang H., Pan K.H., Cohen S.N. Senescence-specific gene expression fingerprints reveal cell-type-dependent physical clustering of up-regulated chromosomal loci. Proc. Natl Acad. Sci. USA. 100:2003;3251-3256.
    • (2003) Proc. Natl Acad. Sci. USA , vol.100 , pp. 3251-3256
    • Zhang, H.1    Pan, K.H.2    Cohen, S.N.3


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