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Volumn 249, Issue , 2000, Pages 135-164

DNA methylation inhibitors in the treatment of leukemias, myelodysplastic syndromes and hemoglobinopathies: Clinical results and possible mechanisms of action

Author keywords

[No Author keywords available]

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; AZACITIDINE;

EID: 0034105545     PISSN: 0070217X     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-3-642-59696-4_9     Document Type: Review
Times cited : (165)

References (8)
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    • Abele R, Clavel M, Dodion P, Bruntsch U, Gundersen S, Smyth J, Renard J, Van Glabbeke M, Pinedo HM (1987) The EORTC early clinical trials cooperative group experience with azacitidine-2′-deoxycytidine (NSC 127716) in patients with colo-rectal, head and neck, renal carcinomas and malignant melanomas. Eur J Cancer Clin Oncol 23:1921-1924
    • (1987) Eur J Cancer Clin Oncol , vol.23 , pp. 1921-1924
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  • 2
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    • Extensive intra- and interindividual heterogeneity of p15/INK4B methylation in acute myeloid leukemia
    • Aggerholm A, Guldberg P, Hokland M, Hokland P (1999) Extensive intra- and interindividual heterogeneity of p15/INK4B methylation in acute myeloid leukemia. Cancer Res 59:436-441
    • (1999) Cancer Res , vol.59 , pp. 436-441
    • Aggerholm, A.1    Guldberg, P.2    Hokland, M.3    Hokland, P.4
  • 3
    • 0024382309 scopus 로고
    • Effect of 5-Azacytidine on gene expression in marrow stromal cells
    • Andrews F, Nemunaitis J, Tompkins CH, Singer JW (1989) Effect of 5-Azacytidine on gene expression in marrow stromal cells. Mol Cell Biol 9:2748-2751
    • (1989) Mol Cell Biol , vol.9 , pp. 2748-2751
    • Andrews, F.1    Nemunaitis, J.2    Tompkins, C.H.3    Singer, J.W.4
  • 4
    • 0026623298 scopus 로고
    • Synergistic cytotoxicity with 2′-deoxy-5-azacytidine and topotecan in vitro and in vivo
    • Anzai H, Frost P, Abruzzese JL (1992) Synergistic cytotoxicity with 2′-deoxy-5-azacytidine and topotecan in vitro and in vivo. Cancer Res 52:2180-2185
    • (1992) Cancer Res , vol.52 , pp. 2180-2185
    • Anzai, H.1    Frost, P.2    Abruzzese, J.L.3
  • 5
    • 0026688084 scopus 로고
    • Age-related incidence and other epidemiological aspects of myelodysplastic syndromes
    • Aul C, Gattermann N, Schneider W (1992) Age-related incidence and other epidemiological aspects of myelodysplastic syndromes. Br J Haematol 82:358-367
    • (1992) Br J Haematol , vol.82 , pp. 358-367
    • Aul, C.1    Gattermann, N.2    Schneider, W.3
  • 6
    • 0024355064 scopus 로고
    • Pharmacodynamic and DNA methylation studies of high-dose-1-β-D-arabinofuranosyl cytosine before and after in vivo 5-azacytidine treatment in pediatric patients with refractory acute lymphocytic leukemia
    • Avramis VI, Mecum RA, Nyce J, Steele DA, Holcenberg JS (1989) Pharmacodynamic and DNA methylation studies of high-dose-1-β-D-arabinofuranosyl cytosine before and after in vivo 5-azacytidine treatment in pediatric patients with refractory acute lymphocytic leukemia. Cancer Chemother Pharmacol 24:203-210
    • (1989) Cancer Chemother Pharmacol , vol.24 , pp. 203-210
    • Avramis, V.I.1    Mecum, R.A.2    Nyce, J.3    Steele, D.A.4    Holcenberg, J.S.5
  • 7
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    • Improved remission induction rate with D-ZAPO but unimproved remission duration with addition of immunotherapy to chemotherapy in previously untreated children with ANLL
    • Baehner RL, Bernstein ID, Sather H, Higgins G, McCreadie S, Chard RL, Hammond D (1979) Improved remission induction rate with D-ZAPO but unimproved remission duration with addition of immunotherapy to chemotherapy in previously untreated children with ANLL. Med Pediatric Oncol 7:127-139
    • (1979) Med Pediatric Oncol , vol.7 , pp. 127-139
    • Baehner, R.L.1    Bernstein, I.D.2    Sather, H.3    Higgins, G.4    McCreadie, S.5    Chard, R.L.6    Hammond, D.7
  • 8
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    • Alterations in DNA methylation: A fundamental aspect of neoplasia
    • Baylin SB, Herman JG, Vertino PM, Issa JP (1998) Alterations in DNA methylation: a fundamental aspect of neoplasia. Cancer Res 72:141-196
    • (1998) Cancer Res , vol.72 , pp. 141-196
    • Baylin, S.B.1    Herman, J.G.2    Vertino, P.M.3    Issa, J.P.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.