The therapeutic journey of benzimidazoles: A review

Bioorganic and Medicinal Chemistry

Volumn 20, Issue 21, 2012, Pages 6208-6236

  Bansal, Yogita ^a   Silakari, Om ^a  

^a PUNJABI UNIVERSITY   (India)

Author keywords

Anti inflammatory; Anticancer; Anticoagulants; Antihypertensives; Antimicrobials; Antioxidants; Antiparasites; Antivirals; Benzimidazole; CNS stimulants and depressants

Indexed keywords

1 (5 CHLORO 2 BENZIMIDAZOLYLCARBONYL) 4 METHYLPIPERAZINE; 1 CYCLOPROPYL 1,3 DIHYDRO 3 [[1 (4 HYDROXYBUTYL) 1H BENZIMIDAZOL 2 YL]METHYL] 2H IMIDAZO[4,5 C]PYRIDIN 2 ONE; 1,3 DIARYLPYRAZINOL[1,2 A]BENZIMIDAZOLE; 2 (5 ETHYL 2 PYRIDYL)BENZIMIDAZOLE; 2 BUTYL 4 CHLORO 1 [[2' (1H TETRAZOL 5 YL) 4 BIPHENYLYL]METHYL] 5 IMIDAZOLECARBOXYLIC ACID; 4 HALO 6 [2 (4 ARYLPIPERAZIN 1 YL)ETHYL] 1H BENZIMIDAZOLE DERIVATIVE; 5 HYDROXY 2 METHYLBENZIMIDAZOLE; 5 HYDROXYBENZIMIDAZOLE; ALPHA INTERFERON; BENZIMIDAZOLE DERIVATIVE; CANDESARTAN; CANDESARTAN HEXETIL; DABIGATRAN; ENVIROXIME; IBUPROFEN; INDOMETACIN; LOSARTAN; N [2 AMINO 1 (ISOPROPYLSULFONYL) 1H BENZO[D]IMIDAZOL 6 YL] 3 (TRIFLUOROMETHYL)BENZENESULFONAMIDE; OMEPRAZOLE; PHENYLBUTAZONE; PYRAZOLINE DERIVATIVE; PYRIMIDINE DERIVATIVE; PYRIMIDO[1,2 A]BENZIMIDAZOLE 3(4H)ONE; PYRROLO[1,2 A]BENZIMIDAZOLE DERIVATIVE; SNS 314; TELMISARTAN; THIAZOLE DERIVATIVE; TIARAMIDE; TIMEGADINE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANALGESIC ACTIVITY; ANTHELMINTIC ACTIVITY; ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; ANTIHYPERTENSIVE ACTIVITY; ANTIINFLAMMATORY ACTIVITY; ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; ANTIPYRETIC ACTIVITY; ANTIVIRAL ACTIVITY; ANTIVIRAL RESISTANCE; ARTHRITIS; BACTERICIDAL ACTIVITY; DOSE RESPONSE; DRUG BIOAVAILABILITY; DRUG CYTOTOXICITY; DRUG DESIGN; DRUG EFFICACY; DRUG IDENTIFICATION; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SAFETY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; GASTROINTESTINAL IRRITATION; HUMAN; HYPERALGESIA; HYPERTENSION; IC 50; NONHUMAN; OBESITY; PAIN; PAW EDEMA; QUANTITATIVE STRUCTURE ACTIVITY RELATION; REVIEW; STRUCTURE ACTIVITY RELATION; SUBSTITUTION REACTION;

ANIMALS; BENZIMIDAZOLES; CHEMISTRY, PHARMACEUTICAL; DRUG DESIGN; HUMANS; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84867581119     PISSN: 09680896     EISSN: 14643391     Source Type: Journal    
DOI: 10.1016/j.bmc.2012.09.013     Document Type: Review

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