Anti-inflammatory, analgesic and antiamoebic activity evaluation of pyrimido[1,6-a]benzimidazole derivatives synthesized by the reaction of ketoisothiocyanates with mono and diamines

European Journal of Medicinal Chemistry

Volumn 37, Issue 10, 2002, Pages 835-843

  Sondhi, Sham M ^a   Rajvanshi, Shefali ^a   Johar, Monika ^a   Bharti, Neelam ^b   Azam, Amir ^b   Singh, Ashok Kumar ^c  

^a INDIAN INSTITUTE OF TECHNOLOGY ROORKEE   (India)

^b JAMIA MILLIA ISLAMIA CENTRAL UNIVERSITY   (India)

^c LLRM MEDICAL COLLEGE   (India)

Author keywords

Analgesic; Anti inflammatory; Antiamoebic; Pyrimido 1,6 a benzimidazoles

Indexed keywords

2 NITROANILINE; 2,3 DIAMINOPURIDINE 1,4 DIAMINOBUTANE; 3 ISOTHIOCYANATOBUTANAL; 4,5 DIMETHYL 1,2 PHENYLENEDIAMINE; ANALGESIC AGENT; ANILINE DERIVATIVE; ANTIAMEBIC AGENT; ANTIINFLAMMATORY AGENT; BENZIMIDAZOLE DERIVATIVE; BUTYRALDEHYDE; DIAMINE DERIVATIVE; IBUPROFEN; MONOAMINE DERIVATIVE; THIOCYANIC ACID DERIVATIVE; UNCLASSIFIED DRUG; CARRAGEENAN; NONSTEROID ANTIINFLAMMATORY AGENT; PYRIDINE DERIVATIVE;

AMEBIASIS; ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG SYNTHESIS; ENTAMOEBA HISTOLYTICA; FEMALE; IN VITRO STUDY; IN VIVO STUDY; METHYLATION; MOUSE; NONHUMAN; PAW EDEMA; POLYMERIZATION; RAT; TREATMENT OUTCOME; ANIMAL; CHEMICALLY INDUCED DISORDER; CHEMISTRY; EDEMA; IC 50; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PAIN ASSESSMENT; PATHOLOGY; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

AMEBICIDES; ANALGESICS; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BENZIMIDAZOLES; CARRAGEENAN; EDEMA; ENTAMOEBA HISTOLYTICA; INHIBITORY CONCENTRATION 50; MAGNETIC RESONANCE SPECTROSCOPY; MICE; PAIN MEASUREMENT; PYRIDINES; RATS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0036809043     PISSN: 02235234     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0223-5234(02)01403-4     Document Type: Article

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