Synthesis and in vitro activity of dicationic bis-benzimidazoles as a new class of anti-MRSA and anti-VRE agents

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 5, 2009, Pages 1292-1295

  Hu, Laixing ^a   Kully, Maureen L ^b   Boykin, David W ^a   Abood, Norman ^c  

^a GEORGIA STATE UNIVERSITY   (United States)

^b NAEJA Pharmaceutical Inc   (Canada)

^c Immtech Pharmaceuticals Inc   (United States)

Author keywords

Antibacterials; Benzimidazoles; Diamidines

Indexed keywords

BENZIMIDAZOLE DERIVATIVE; CIPROFLOXACIN; DB 325; PENICILLIN G; UNCLASSIFIED DRUG; VANCOMYCIN;

ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL STRAIN; DRUG ACTIVITY; DRUG MECHANISM; DRUG STRUCTURE; DRUG SYNTHESIS; IN VITRO STUDY; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; VANCOMYCIN RESISTANT ENTEROCOCCUS;

ANTI-BACTERIAL AGENTS; BENZIMIDAZOLES; DRUG RESISTANCE, MULTIPLE, BACTERIAL; ENTEROCOCCUS FAECIUM; METHICILLIN RESISTANCE; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; STRUCTURE-ACTIVITY RELATIONSHIP; VANCOMYCIN RESISTANCE;

BACTERIA (MICROORGANISMS); METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS;

EID: 60449094774     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.01.075     Document Type: Article

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