Angiotensin II receptor type 1 (AT1) selective nonpeptidic antagonists - A perspective

Bioorganic and Medicinal Chemistry

Volumn 18, Issue 24, 2010, Pages 8418-8456

  Naik, Prashant ^a   Murumkar, Prashant ^a   Giridhar, Rajani ^a   Yadav, Mange Ram ^a  

^a M S UNIVERSITY OF BARODA   (India)

Author keywords

Angiotensin receptor blocker; Antihypertensive; AT1 receptor; Molecular modeling; Renin angiotensin system

Indexed keywords

2 BUTYL 4 CHLORO 1 [[2' (1H TETRAZOL 5 YL) 4 BIPHENYLYL]METHYL] 5 IMIDAZOLECARBOXYLIC ACID; 3 TERT BUTYL 1 PROPYL 5 [[2' (1H TETRAZOL 5 YL) 1,1' BIPHENYL 4 YL]METHYL] 1H PYRAZOLE 4 CARBOXYLIC ACID; ANGIOTENSIN 1 RECEPTOR ANTAGONIST; ANGIOTENSIN II; BMS 180560; CANDESARTAN; CI 996; DMP 811; ELISARTAN; EPROSARTAN; FORASARTAN; IRBESARTAN; L 158854; LOSARTAN; LOSARTAN POTASSIUM; N (HETEROBIARYL)METHYLIMIDAZOLE DERIVATIVE; OLMESARTAN; RU 65868; SC 50560; SC 51316; SC 51757; SC 51895; SC 52892; SC 54629; TELMISARTAN; UNCLASSIFIED DRUG; UNINDEXED DRUG; VALSARTAN; XH 148; XR 510; ZOLASARTAN;

DRUG MECHANISM; HUMAN; HYPERTENSION; NONHUMAN; PROTEIN FUNCTION; PROTEIN STRUCTURE; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; REVIEW; STRUCTURE ACTIVITY RELATION;

ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; ANGIOTENSIN RECEPTOR ANTAGONISTS; ANTIHYPERTENSIVE AGENTS; HUMANS; LOSARTAN;

EID: 78649449966     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2010.10.043     Document Type: Review

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