SAR studies of 6-aryl-1,3-dihydrobenzimidazol-2-ones as progesterone receptor antagonists

Bioorganic and Medicinal Chemistry Letters

Volumn 15, Issue 15, 2005, Pages 3600-3603

  Terefenko, Eugene A ^a   Kern, Jeffrey ^a   Fensome, Andrew ^a   Wrobel, Jay ^a   Zhu, Yuan ^a   Cohen, Jeffrey ^a   Winneker, Richard ^a   Zhang, Zhiming ^a   Zhang, Puwen ^a  

^a PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5 (3 CYCLOPENTYL 2 OXO 2,3 DIHYDRO 1H BENZIMIDAZOL 5 YL) 1 METHYL 1H PYRROLE 2 CARBONITRILE; 5 (3 ISOPROPYL 2 OXO 2,3 DIHYDRO 1H BENZIMIDAZOL 5 YL) 1 METHYL 1H PYRROLE 2 CARBONITRILE; ANTIGESTAGEN; BENZIMIDAZOLE DERIVATIVE; BENZOXAZINONE DERIVATIVE; OXINDOLE; PYRROLE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL PROCEDURES; CONTROLLED STUDY; DRUG ACTIVITY; DRUG POTENCY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; STRUCTURE ACTIVITY RELATION;

BENZIMIDAZOLES; BENZOXAZINES; BINDING SITES; BREAST NEOPLASMS; CELL LINE, TUMOR; FEMALE; HORMONE ANTAGONISTS; HUMANS; INDOLES; PYRROLES; RECEPTORS, PROGESTERONE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 21744452625     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2005.05.082     Document Type: Article

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