Design; Synthesis and Antihypertensive activity of 4'-(2-{2-[(2-chloro-benzylidene)-amino]-phenyl}-5-nitro-benzoimidazol-1-ylmethyl)] biphenyl-2-carboxylic acid

International Journal of Advances in Pharmaceutical Sciences

Volumn 1, Issue 3, 2010, Pages 249-262

  Sharma, M C ^a   Kohli, D V ^a   Sharma, Smita ^b  

^a DR H S GOUR UNIVERSITY   (India)

^b Department of Chemistry Yadhunath Mahavidyalya Bhind ^*  (India)

Author keywords

Angiotensin ii; Benzimidazoles; Biphenyl 2 carboxylic acid; Hypertension

Indexed keywords

2 (2 AMINOPHENYL) BENZIMIDAZOLE; 2 (5 NITRO 1H BENZIMIDAZOLE 2 YL) PHENYLAMINE; 4' [2 [2 [(2 CHLORO BENZYLIDENE) AMINO] PHENYL] 5 NITRO BENZOIMIDAZOL 1 YLMETHYL]BIPHENYL 2 CARBOXYLIC ACID; 4' [2 [2 [(2 HYDROXY 3 METHOXY BENZYLIDENE) AMINO] PHENYL] 5 NITRO BENZOIMIDAZOL 1 YLMETHYL]BIPHENYL 2 CARBOXYLIC ACID; 4' [2 [2 [(2 HYDROXY 4 METHOXY BENZYLIDENE) AMINO] PHENYL] 5 NITRO BENZOIMIDAZOL 1 YLMETHYL]BIPHENYL 2 CARBOXYLIC ACID; 4' [2 [2 [(2 HYDROXY BENZYLIDENE) AMINO] PHENYL] 5 NITRO BENZOIMIDAZOL 1 YLMETHYL]BIPHENYL 2 CARBOXYLIC ACID; 4' [2 [2 [(2 METHOXY BENZYLIDENE) AMINO] PHENYL] 5 NITRO BENZOIMIDAZOL 1 YLMETHYL]BIPHENYL 2 CARBOXYLIC ACID; 4' [2 [2 [(2,3 DICHLORO BENZYLIDENE) AMINO] PHENYL] 5 NITRO BENZOIMIDAZOL 1 YLMETHYL]BIPHENYL 2 CARBOXYLIC ACID; 4' [2 [2 [(2,5 DICHLORO BENZYLIDENE) AMINO] PHENYL] 5 NITRO BENZOIMIDAZOL 1 YLMETHYL]BIPHENYL 2 CARBOXYLIC ACID; 4' [2 [2 [(2,5 DIMETHOXY BENZYLIDENE) AMINO] PHENYL] 5 NITRO BENZOIMIDAZOL 1 YLMETHYL]BIPHENYL 2 CARBOXYLIC ACID; 4' [2 [2 [(3 CHLORO BENZYLIDENE) AMINO] PHENYL] 5 NITRO BENZOIMIDAZOL 1 YLMETHYL]BIPHENYL 2 CARBOXYLIC ACID; 4' [2 [2 [(3 HYDROXY BENZYLIDENE) AMINO] PHENYL] 5 NITRO BENZOIMIDAZOL 1 YLMETHYL]BIPHENYL 2 CARBOXYLIC ACID; 4' [2 [2 [(3 METHOXY BENZYLIDENE) AMINO] PHENYL] 5 NITRO BENZOIMIDAZOL 1 YLMETHYL]BIPHENYL 2 CARBOXYLIC ACID; 4' [2 [2 [(4 CHLORO BENZYLIDENE) AMINO] PHENYL] 5 NITRO BENZOIMIDAZOL 1 YLMETHYL]BIPHENYL 2 CARBOXYLIC ACID; 4' [2 [2 [(4 DIMETHYLAMINO BENZYLIDENE) AMINO] PHENYL] 5 NITRO BENZOIMIDAZOL 1 YLMETHYL]BIPHENYL 2 CARBOXYLIC ACID; 4' [2 [2 [(4 HYDROXY BENZYLIDENE) AMINO] PHENYL] 5 NITRO BENZOIMIDAZOL 1 YLMETHYL]BIPHENYL 2 CARBOXYLIC ACID; 4' [2 [2 [(4 METHOXY BENZYLIDENE) AMINO] PHENYL] 5 NITRO BENZOIMIDAZOL 1 YLMETHYL]BIPHENYL 2 CARBOXYLIC ACID; 4' [2 [2 [(BENZYLIDENE) AMINO] PHENYL] 5 NITRO BENZOIMIDAZOL 1 YLMETHYL]BIPHENYL 2 CARBOXYLIC ACID; 4' [5 NITRO 2 [2 [(2 NITRO BENZYLIDENE) AMINO] PHENYL] 5 NITRO BENZOIMIDAZOL 1 YLMETHYL]BIPHENYL 2 CARBOXYLIC ACID; 4' [5 NITRO 2 [2 [(3 NITRO BENZYLIDENE) AMINO] PHENYL] 5 NITRO BENZOIMIDAZOL 1 YLMETHYL]BIPHENYL 2 CARBOXYLIC ACID; 4' [5 NITRO 2 [2 [(3,4,5 TRIMETHOXY BENZYLIDENE) AMINO] PHENYL] 5 NITRO BENZOIMIDAZOL 1 YLMETHYL]BIPHENYL 2 CARBOXYLIC ACID; 4' [5 NITRO 2 [2 [(4 NITRO BENZYLIDENE) AMINO] PHENYL] 5 NITRO BENZOIMIDAZOL 1 YLMETHYL]BIPHENYL 2 CARBOXYLIC ACID; 4' ACETYLAMINO METHYLBIPHENYL 2 CARBOXYLIC ACID; 4' BROMOMETHYLBIPHENYL 2 CARBOXYLIC ACID; BENZIMIDAZOLE DERIVATIVE; BIPHENYL CARBOXYLIC ACID; LOSARTAN; LOSARTAN POTASSIUM; MILFASARTAN; TASOSARTAN; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIHYPERTENSIVE ACTIVITY; ARTICLE; BLOOD PRESSURE MEASUREMENT; CHEMICAL STRUCTURE; CONTROLLED STUDY; DOSE RESPONSE; DRUG DESIGN; DRUG SYNTHESIS; HYPERTENSION; MALE; MEAN ARTERIAL PRESSURE; MELTING POINT; NONHUMAN; RAT; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM;

EID: 79953305891     PISSN: None     EISSN: 09761055     Source Type: Journal    
DOI: 10.5138/ijaps.2010.0976.1055.01029     Document Type: Article

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