2-Alkyl-1-(2-aryl-1,1-difluoro-2-hydroxyethyl)benzimidazoles: Potential angiotensin II receptor antagonists

Tetrahedron Letters

Volumn 41, Issue 13, 2000, Pages 2265-2267

  Yagupolskii, Lev M ^a   Fedyuk, Dmitrij V ^a  

^a INSTITUTE OF ORGANIC CHEMISTRY   (Ukraine)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN 2 RECEPTOR ANTAGONIST; BENZIMIDAZOLE DERIVATIVE;

ARTICLE; CHEMICAL REACTION; DRUG STRUCTURE; DRUG SYNTHESIS; REACTION ANALYSIS;

EID: 0034719929     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(00)00148-9     Document Type: Article

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2. Thomas, A. P.; Allott, C. P.; Gibson, K. H.; Major, J. S.; Masek, B. B.; Oldham, A. A.; Ratcliffe, A. H.; Roberts, D. A.; Russell, S. T.; Thomason, D. A. J. Med. Chem. 1992, 35, 877.
3. Burkholder, C.; Dolbier Jr.,W. R.; Medebielle, M. J. Org. Chem. 1998, 63, 5385.
4. 2Br).
5. F-F=231 Hz).
6. Larsen, R. D.; King, A. O.; Chen, C. Y.; Corley, E. G.; Foster, B. S.; Roberts, F. E.; Yang, C.; Lieberman, D. R.; Reamer, R. A.; Tschaen, D. M.; Verhoeven, T. R.; Reider, P. J.; Lo, Y. S.; Rossano, L. T.; Brookes, A. S.; Meloni, D.; Moore, J. R.; Arnett, J. F. J. Org. Chem. 1994, 59, 6391.
7. F-F=218 Hz).