Identification of 1-isopropylsulfonyl-2-amine benzimidazoles as a new class of inhibitors of hepatitis B virus

European Journal of Medicinal Chemistry

Volumn 42, Issue 11-12, 2007, Pages 1358-1364

  Li, Yun Fei ^b   Wang, Gui Feng ^b   Luo, Yu ^a,b   Huang, Wei Gang ^b   Tang, Wei ^b   Feng, Chun Lan ^b   Shi, Li Ping ^b   Ren, Yu Dan ^b   Zuo, Jian Ping ^b   Lu, Wei ^a  

^a EAST CHINA NORMAL UNIVERSITY   (China)

^b SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

Anti HBV activity; Benzimidazoles; Synthesis

Indexed keywords

1 (ISOPROPYLSULFONYL) 1H BENZO[D]IMIDAZOLE 2,5 DIAMINE; 1 (ISOPROPYLSULFONYL) 1H BENZO[D]IMIDAZOLE 2,6 DIAMINE; 1 (ISOPROPYLSULFONYL) 5 NITRO 1H BENZO[D]IMIDAZOL 2 AMINE; 1 (ISOPROPYLSULFONYL) 6 NITRO 1H BENZO[D]IMIDAZOL 2 AMINE; 1 ISOPROPYLSULFONYL 2 AMINE BENZIMIDAZOLE; 6 NITRO 1H BENZO[D]IMIDAZOL 2 AMINE; BENZIMIDAZOLE DERIVATIVE; N (2 AMINO 1 (ISOPROPYLSULFONYL) 1H BENZO[D]IMIDAZOL 6 YL) 4 FLUOROBENZAMIDE; N [2 AMINO 1 (ISOPROPYLSULFONYL) 1H BENZO[D] IMIDAZOL 5 YL]BENZAMIDE; N [2 AMINO 1 (ISOPROPYLSULFONYL) 1H BENZO[D]IMIDAZOL 5 YL] 4 FLUOROBENZAMIDE; N [2 AMINO 1 (ISOPROPYLSULFONYL) 1H BENZO[D]IMIDAZOL 5 YL] 4 METHYLBENZENESULFONAMIDE; N [2 AMINO 1 (ISOPROPYLSULFONYL) 1H BENZO[D]IMIDAZOL 5 YL]BENZAMIDE; N [2 AMINO 1 (ISOPROPYLSULFONYL) 1H BENZO[D]IMIDAZOL 6 YL)]2 CHLOROBENZAMIDE; N [2 AMINO 1 (ISOPROPYLSULFONYL) 1H BENZO[D]IMIDAZOL 6 YL] 2 FLUOROBENZAMIDE; N [2 AMINO 1 (ISOPROPYLSULFONYL) 1H BENZO[D]IMIDAZOL 6 YL] 2,6 DIFLUOROBENZAMIDE; N [2 AMINO 1 (ISOPROPYLSULFONYL) 1H BENZO[D]IMIDAZOL 6 YL] 3 NITROBENZENESULFONAMIDE; N [2 AMINO 1 (ISOPROPYLSULFONYL) 1H BENZO[D]IMIDAZOL 6 YL] 4 METHYLBENZAMIDE; N [2 AMINO 1 (ISOPROPYLSULFONYL) 1H BENZO[D]IMIDAZOL 6 YL] 4 METHYLBENZENESULFONAMIDE; N [2 AMINO 1 (ISOPROPYLSULFONYL) 1H BENZO[D]IMIDAZOL 6 YL]BENZAMIDE; N [2 AMINO 1 (ISOPROPYLSULFONYL) 1H BENZO[D]IMIDAZOL 6 YL]BENZENESULFONAMIDE; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG IDENTIFICATION; DRUG MECHANISM; DRUG SAFETY; DRUG SELECTIVITY; DRUG SYNTHESIS; HEPATITIS B VIRUS; HUMAN; HUMAN CELL; VIRUS INHIBITION;

ANIMALS; BENZIMIDAZOLES; CATTLE; CELL DEATH; CELL LINE, TUMOR; DNA, VIRAL; HEPATITIS B VIRUS; HUMANS; INHIBITORY CONCENTRATION 50;

EID: 36248956157     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2007.03.005     Document Type: Article

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