Antiinflammatory and antinociceptive effects of the selective histamine H4-receptor antagonists JNJ7777120 and VUF6002 in a rat model of carrageenan-induced acute inflammation

European Journal of Pharmacology

Volumn 563, Issue 1-3, 2007, Pages 240-244

  Coruzzi, Gabriella ^a   Adami, Maristella ^a   Guaita, Elena ^a   de Esch, Iwan J P ^b   Leurs, Rob ^b  

^a UNIVERSITY OF PARMA   (Italy)

^b VU UNIVERSITY AMSTERDAM   (Netherlands)

Author keywords

Carrageenan; Histamine H4 receptor antagonists; JNJ7777120; Paw edema; Thermal hyperalgesia; VUF6002

Indexed keywords

ANTIHISTAMINIC AGENT; CARRAGEENAN; JNJ 7777120; UNCLASSIFIED DRUG; VUF 6002; VUF 6007;

ANALYTICAL ERROR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DISEASE COURSE; HYPERALGESIA; INFLAMMATION; MALE; NONHUMAN; PAW EDEMA; PRIORITY JOURNAL; RAT;

ANALGESICS; ANIMALS; ANTI-INFLAMMATORY AGENTS; BENZIMIDAZOLES; CARRAGEENAN; DISEASE MODELS, ANIMAL; EDEMA; HEAT; HISTAMINE ANTAGONISTS; HYPERALGESIA; INDOLES; INFLAMMATION; MALE; PAIN MEASUREMENT; PIPERAZINES; RATS; RATS, WISTAR; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, HISTAMINE; TIME FACTORS;

EID: 34247137952     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2007.02.026     Document Type: Article

References (30)

1. 1 receptors in scratching induced by histamine receptor agonists in Balb C mice. Br. J. Pharmacol. 142 (2004) 374-380
2. 4 receptor. Br. J. Pharmacol. 140 (2003) 1117-1127
3. 3 receptors. J. Pain 6 (2005) 193-200
4. Damas J., and Remacle-Volon G. Mast cell amines and the oedema induced by zymosan and carrageenans in rats. Eur. J. Pharmacol. 121 (1986) 367-376
5. 4 receptor as a new therapeutic target for inflammation. Trends Pharmacol. Sci. 26 (2005) 462-469
6. Di Rosa M., Giroud J.P., and Willoughby D.A. Studies on the mediators of the acute inflammatory response induced in rats in different sites by carrageenan and turpentine. J. Pathol. 104 (1971) 15
7. + T cells. J. Immunol. 176 (2006) 7062-7070
8. Farzin D., and Norsati F. Modification of formalin-induced nociception by different histamine receptor agonists and antagonists. Eur. Neuropsychoparmacol. 17 (2007) 122-128
9. + T cells. J. Pharmacol. Exp. Ther. 303 (2002) 300-307
10. Girard P., Pansart Y., Coppè M.C., Verniers D., and Gillardin J.M. Role of the histamine system in nefopam-induced antinociception in mice. Eur. J. Pharmacol. 503 (2004) 63-69
11. 4 receptor mediates chemotaxis and calcium mobilization of mast cells. J. Pharmacol. Exp. Ther. 305 (2003) 1212-1221
12. Hough L.B. Genomics meets histamine receptors: new subtypes, new receptors. Mol. Pharmacol. 59 (2001) 415-419
13. 4 ligands. Mini-Rev. Med. Chem. 4 (2004) 993-1000
14. Jett M.F., Ramesha C.S., Brown C.D., Chiu S., Emmett C., Voronin T., Sun T., O'Yang C., Hunter J.C., Eglen R.M., and Johnson R.M. Characterization of the analgesic and anti-inflammatory activities of ketorolac and its enantiomers in the rat. J. Pharmacol. Exp. Ther. 288 (1999) 1288-1297
15. Kulkarni S.K., Mehta A.K., and Kunchandy J. Anti-inflammatory actions of clonidine, guanfacine and B-HT 920 against various inflammagen-induced acute paw oedema in rats. Arch. Int. Pharmacodyn. Ther. 279 (1986) 324-334
16. Lim H.D., Smits R.A., Leurs R., and de Esch I.J. The emerging role of the histamine H4 receptor in anti-inflammatory therapy. Curr. Top. Med. Chem. 6 (2006) 1365-1373
17. 4 receptor mediates eosinophil chemotaxis with cell shape change and adhesion molecule up-regulation. Br. J. Pharmacol. 142 (2004) 161-171
18. 4 receptor during rat development. XXX EHRS meeting, Dusseldorf/Köln, Germany; 28 April-2 May (2004)
19. 1 receptor activation in rodents. Life Sci. 63 (1998) 463-476
20. 4 receptor on human eosinophils-role in eosinophil chemotaxis. J. Recept. Sign. Transduct. Res. 22 (2002) 433-450
21. Parada C.A., Tambeli C.H., Cunha F.Q., and Ferreira S.H. The major role of peripheral release of histamine and 5-hydroxytryptamine in formalin-induced nociception. Neuroscience 102 (2001) 937-944
22. Seibert K., Zhang Y., Leahy K., Hauser S., Masferrer J., Perkins W., Lee L., and Isakson P. Pharmacological and biochemical demonstration of the role of cyclooxygenase 2 in inflammation and pain. Proc. Natl. Acad. Sci. USA 91 (1994) 12013-12017
23. 4 production and mast cell-dependent neutrophil recruitment induced by zymosan in vivo. J. Pharmacol. Exp. Ther. 307 (2003) 1072-1078
24. 4 receptor in zymosan-induced neutrophil recruitment from the bone marrow: comparison with carrageenan. J. Pharmacol. Exp. Ther. 310 (2004) 272-280
25. 4 receptor antagonists. Bioorg. Med. Chem. Lett. 14 (2004) 5251-5256
26. Thoburn K.K., Hough L.B., Nalwalk J.W., and Mischler S.A. Histamine-induced modulation of nociceptive responses. Pain 58 (1994) 29-37
27. 4 receptor antagonist with anti-inflammatory properties. J. Pharmacol. Exp. Ther. 309 (2004) 404-413
28. 4 receptor antagonists on experimental colitis in the rat. Eur. J. Pharmacol. 522 (2005) 130-138
29. Vinegar R., Schreiber W., and Hugo R. Biphasic development of carrageenan oedema in rat. J. Pharmacol. Exp. Ther. 166 (1969) 96-103
30. Winter C.A., Risley E.A., and Nuss G.W. Carrageenan-induced oedema in hind paw of the rat as an assay for anti-inflammatory drugs. Proc. Soc. Exp. Biol. Med. 111 (1962) 544-547