Anthelmintic activity of benzimidazole derivatives against Toxocara canis second-stage larvae and Hymenolepis nana adults

Acta Tropica

Volumn 109, Issue 3, 2009, Pages 232-235

  Márquez Navarro, Adrián ^a   Nogueda Torres, Benjamín ^a   Hernández Campos, Alicia ^b   Soria Arteche, Olivia ^c   Castillo, Rafael ^b   Rodríguez Morales, Sergio ^b   Yépez Mulia, Lilián ^d   Hernández Luis, Francisco ^b  

^a INSTITUTO POLITÉCNICO NACIONAL   (Mexico)

^b UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

^c DEPARTAMENTO DE SISTEMAS BIOLÓGICOS   (Mexico)

^d INSTITUTO MEXICANO DEL SEGURO SOCIAL   (Mexico)

Author keywords

Benzimidazole analogues; Hymenolepis nana; Prodrugs; Toxocara canis

Indexed keywords

BENZIMIDAZOLE DERIVATIVE;

ADULT; DRUG; FLATWORM; LARVA; NEMATODE;

ANTHELMINTIC ACTIVITY; ARTICLE; CESTODE; DRUG EFFICACY; DRUG SCREENING; DRUG STRUCTURE; FASCIOLA HEPATICA; HYMENOLEPIS NANA; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; TOXOCARA CANIS;

ALBENDAZOLE; ANIMALS; ANTHELMINTICS; BENZIMIDAZOLES; FEMALE; HYMENOLEPIASIS; HYMENOLEPIS NANA; LARVA; MICE; PARASITIC SENSITIVITY TESTS; TOXOCARA CANIS;

CESTODA; FASCIOLA HEPATICA; HYMENOLEPIS NANA; TOXOCARA CANIS;

EID: 59049097857     PISSN: 0001706X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.actatropica.2008.11.014     Document Type: Article

References (16)

1. Amato N.V., Moreira A.A., Ferreira G.M., do Nascimento S.A., Matsubara L., Campos R., and Pinto P.L. Evaluation of the therapeutic effect of albendazole on experimental and human infections by Hymenolepis nana. Rev. Inst. Med. Trop. Sao Paulo 32 (1990) 185-188
2. Beaver P.C. The nature of visceral larva migrans. J. Parasitol. 55 (1969) 3-12
3. Despommier D. Toxocariasis: clinical aspects, epidemiology, medical ecology, and molecular aspects. Clin. Microbiol. Rev. 16 (2003) 265-272
4. Di Lernia V., Ricci C., and Albertini G. Skin eruption associated with Hymenolepis nana infection. Int. J. Dermatol. 43 (2004) 357-359
5. Dixon J.B., and Arai P. Anthelmintic-induced destrobilation and its influence on calculated drug efficacy in Hymenolepis diminuta infections in rats. J. Parasitol. 77 (1991) 769-774
6. Hernández-Campos A., Ibarra V.F., Vera M.Y., Rivera F.N., and Castillo R. Synthesis and fasciolicidal activity of 5-chloro-2-methylthio-6-(1-naphthyloxy)-1H-benzimidazole. Chem. Pharm. Bull. 50 (2002) 649-652
7. Hernández-Luis F., Castillo R., Yépez-Mulia L., Cedillo R., Martínez V.G., Morales H.R., Jung H., Sánchez M., Hernández-Campos A., Viveros N., and Muñoz O. Preparation of N-methoxycarbonyl-N′-[2-nitro-4(5)-propylthiophenyl]thiourea as prodrugs of albendazole. Bioorg. Med. Chem. Lett. 6 (1996) 2231-2236
8. Hernández-Luis F., Hernández-Campos A., Yépez-Mulia L., Cedillo R., and Castillo R. Synthesis and hydrolytic stability studies of albendazole carrier prodrugs. Bioorg. Med. Chem. Lett. 11 (2001) 1359-1362
9. Kiuchi F., Miyashita N., Tsuda Y., Kondo K., and Yoshimura H. Studies on crude drugs effective on visceral larva migrans. I. Identification of larvicidal principles in betel nuts. Chem. Pharm. Bull. 35 (1987) 2880-2886
10. Köhler P. The biochemical basis of anthelmintic action and resistance. Int. J. Parasitol. 31 (2001) 336-345
11. Oaks J., and Kayes S. Artificial hatching and culture of Toxocara canis second stage larvae. J. Parasitol. 65 (1979) 969-970
12. Raether W., and Hänel H. Epidemiology, clinical manifestations and diagnosis of zoonotic cestode infections: an update. Parasitol. Res. 91 (2003) 412-438
13. Rivera J.C., Yépez-Mulia L., Hernández-Campos A., Moreno E.R., Castillo R., Navarrete-Vazquez G., Fuentes N.I., and Jung C.H. Biopharmaceutic evaluation of novel anthelmintic (1H-benzimidazol-5(6)-yl)carboxamide derivatives. Int. J. Pharm. 343 (2007) 159-165
14. Silverman R.B. The Organic Chemistry of Drug Design and Drug Action. second edition (2004), Elsevier Academic Press, USA p. 500
15. Waller P. Global perspectives on nematode parasite control in ruminant livestock: the need to adopt alternatives to chemotherapy, with emphasis on biological control. Anim. Health Res. Rev. 4 (2003) 35-43
16. Wermuth C.G. Similarity in drugs: reflections on analogue design. Drug Discov. Today 11 (2006) 348-354