2-Aryl benzimidazoles: Human SCD1-specific stearoyl coenzyme-A desaturase inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 22, 2010, Pages 6366-6369

  Powell, David A ^a   Ramtohul, Yeeman ^a   Lebrun, Marie Eve ^a   Oballa, Renata ^a   Bhat, Sathesh ^a   Falgueyret, Jean Pierre ^a   Guiral, Sebastien ^a   Huang, Zheng ^a   Skorey, Kathryn ^a   Tawa, Paul ^a   Zhang, Lei ^a  

^a MERCK FROSST CENTRE FOR THERAPEUTIC RESEARCH   (Canada)

Author keywords

Desaturase; SCD; Stearoyl CoA

Indexed keywords

2 ARYL BENZIMIDAZOLE; ACYL COENZYME A DESATURASE 1; BENZIMIDAZOLE DERIVATIVE; OXYGENASE INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL ACTIVITY; CONTROLLED STUDY; DRUG SELECTIVITY; ENZYME ACTIVITY; ENZYME INHIBITION; MOUSE; NONHUMAN;

ANIMALS; BENZIMIDAZOLES; ENZYME INHIBITORS; LIVER; MICE; STEAROYL-COA DESATURASE;

EID: 77958034431     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.09.094     Document Type: Article

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