Synthesis and antiviral activity against Coxsackie virus B3 of some novel benzimidazole derivatives

Bioorganic and Medicinal Chemistry Letters

Volumn 15, Issue 2, 2005, Pages 267-269

  Cheng, Jun ^a   Xie, Jiangtao ^a   Luo, Xianjin ^a  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

Antiviral; Benzimidazole; Coxsackie virus B3

Indexed keywords

ANTIVIRUS AGENT; BENZIMIDAZOLE DERIVATIVE;

ANIMAL CELL; ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; COXSACKIE VIRUS B3; DRUG POTENCY; DRUG SCREENING; DRUG SYNTHESIS; NONHUMAN; RNA VIRUS; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTIVIRAL AGENTS; BENZIMIDAZOLES; CERCOPITHECUS AETHIOPS; ENTEROVIRUS B, HUMAN; MICROBIAL SENSITIVITY TESTS; STRUCTURE-ACTIVITY RELATIONSHIP; VERO CELLS; VIRUS REPLICATION;

COXSACKIEVIRUS;

EID: 10644297155     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2004.10.087     Document Type: Article

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8. 1H NMR (400 MHz, DMSO) δ: 3.52-3.57 (q, 2H), 3.63-3.67 (q, 2H), 4.98-5.00 (t, 1H), 7.34-7.38 (t, 1H), 7.56-7.59 (m, 1H), 7.69-7.72 (d, 1H), 7.87-7.90 (d, 1H), 8.02-8.06 (m, 1H), 8.45-8.47 (d, 1H), 8.76-8.77 (m, 1H), 10.14-10.16 (t, 1H), 13.62 (s, 1H)