Relaxant activity of 2-(substituted phenyl)-1H-benzimidazoles on isolated rat aortic rings. Design and synthesis of 5-nitro derivatives

Life Sciences

Volumn 79, Issue 5, 2006, Pages 430-435

  Estrada Soto, Samuel ^a   Villalobos Molina, Rafael ^b   Aguirre Crespo, Francisco ^a   Vergara Galicia, Jorge ^a   Moreno Díaz, Hermenegilda ^a   Torres Piedra, Mariana ^a   Navarrete Vázquez, Gabriel ^a  

^a UNIVERSIDAD AUTÓNOMA DEL ESTADO DE MORELOS   (Mexico)

^b UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

Author keywords

Benzimidazole; Endothelium; Rat aorta; Vascular relaxation

Indexed keywords

2 (4 METHOXYPHENYL) 5 NITRO 1H BENZIMIDAZOLE; 2 (5 NITRO 1H BENZIMIDAZOL 2 YL)PHENOL; BENZIMIDAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG DESIGN; DRUG POTENCY; DRUG SYNTHESIS; ENDOTHELIUM; HYPERTENSION; IC 50; IN VITRO STUDY; MALE; NONHUMAN; RAT; RAT STRAIN; STRUCTURE ACTIVITY RELATION; SUBSTITUTION REACTION; VASCULAR RING; VASODILATATION;

ANIMALS; AORTA; BENZIMIDAZOLES; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIUM-DEPENDENT RELAXING FACTORS; MALE; RATS; RATS, WISTAR;

EID: 33745038028     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2006.01.019     Document Type: Article

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