Synthesis and structure-activity relationship of dicationic diaryl ethers as novel potent anti-MRSA and anti-VRE agents

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 16, 2009, Pages 4626-4629

  Hu, Laixing ^a   Kully, Maureen L ^b   Boykin, David W ^a   Abood, Norman ^c  

^a GEORGIA STATE UNIVERSITY   (United States)

^b NAEJA Pharmaceutical Inc   (Canada)

^c Immtech Pharmaceuticals Inc   (United States)

Author keywords

Antibacterials; Benzimidazoles; Diamidines; Indoles

Indexed keywords

ANTIINFECTIVE AGENT; PIPERIDINE DERIVATIVE; THIOMORPHOLINE DERIVATIVE;

ANTIBACTERIAL ACTIVITY; ARTICLE; DRUG ACTIVITY; DRUG POTENCY; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; NONHUMAN; STRUCTURE ACTIVITY RELATION; VANCOMYCIN RESISTANT ENTEROCOCCUS;

ANTI-BACTERIAL AGENTS; BENZIMIDAZOLES; ENTEROCOCCUS; ETHERS; INDOLES; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; MICROBIAL SENSITIVITY TESTS; PENTAMIDINE; PHENYL ETHERS; STRUCTURE-ACTIVITY RELATIONSHIP; VANCOMYCIN RESISTANCE;

BACTERIA (MICROORGANISMS); METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS;

EID: 67651094077     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.06.077     Document Type: Article

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