Synthesis, antiviral and antitumor activity of 2-substituted-5-amidino-benzimidazoles

Bioorganic and Medicinal Chemistry

Volumn 15, Issue 13, 2007, Pages 4419-4426

  Starčević, Kristina ^a   Kralj, Marijeta ^b   Ester, Katja ^b   Sabol, Ivan ^b   Grce, Magdalena ^b   Pavelić, Krešimir ^b   Karminski Zamola, Grace ^a  

^a UNIVERSITY OF ZAGREB   (Croatia)

^b RUDER BO KOVI INSTITUTE   (Croatia)

Author keywords

Amidines; Antitumor activity; Antiviral activity; Benzimidazoles; Imidazole; N Methyl pyrrole; Pyridine

Indexed keywords

1 METHYLPYRROLE; 2 (1 METHYL 1H PYRROL 2 YL) 1H BENZIMIDAZOLE 5 CARBOXAMIDINE; 2,5 BENZIMIDAZOLE; 5 (4,5 DIHYDRO 1H IMIDAZOL 2YL) 2 (1METHYL 1H PYRROL 2 YL) 1H BENZIMIDAZOLE 5 CARBOXAMIDINE; 5 (4,5 DIHYDRO 1H IMIDAZOL 2YL) 2 PYRIDIN 2 YL 1H BENZIMIDAZOLE 5 CARBOXAMIDINE; BENZIMIDAZOLE; BENZIMIDAZOLE DERIVATIVE; HETEROCYCLIC COMPOUND; IMIDAZOLE; IMIDAZOLINYLAMIDINO; N ISOPROPYL 2 PYRIDIN 2 YL 1H BENZIMIDAZOLE 5 CARBOXAMIDINE; PYRIDINE; UNCLASSIFIED DRUG;

ADENOVIRUS; ANTINEOPLASTIC ACTIVITY; ANTIVIRAL ACTIVITY; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CONTROLLED STUDY; COXSACKIE VIRUS; DOSE RESPONSE; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; ECHO VIRUS; HUMAN; HUMAN CELL; SUSTAINED RELEASE PREPARATION; VIRUS REPLICATION;

ADENOVIRIDAE; ANTINEOPLASTIC AGENTS; ANTIVIRAL AGENTS; BENZIMIDAZOLES; CELL LINE, TUMOR; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; ENTEROVIRUS; FIBROBLASTS; HELA CELLS; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; SPECTROPHOTOMETRY, INFRARED; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 34248647896     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2007.04.032     Document Type: Article

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