Synthesis and pharmacological activity of aroylmethyl derivatives of tricyclic benzimidazole systems containing hydroxy groups in aroyl radicals

Pharmaceutical Chemistry Journal

Volumn 41, Issue 3, 2007, Pages 126-130

  Anisimova, V A ^a   Tolpygin, I E ^a   Spasov, A A ^b   Kosolapov, V A ^b   Stepanov, A V ^b   Orlova, A A ^b   Naumenko, L V ^b  

^a SOUTHERN FEDERAL UNIVERSITY   (Russian Federation)

^b VOLGOGRAD STATE MEDICAL UNIVERSITY   (Russian Federation)

Author keywords

[No Author keywords available]

Indexed keywords

10 (3,4 DIMETHOXYPHENACYL) 2,3,4,10 TETRAHYDROPYRIMIDO[1,2 A]BENZIMIDAZOLE HYDROBROMIDE; 10 (3,5 DI TERT BUTYL 4 HYDROXYPHENACYL) 2,3,4,10 TETRAHYDROPYRIMIDO[1,2A]BENZIMIDAZOLE HYDROBROMIDE; 10 (4 HYDROXYPHENACYL) 2,3,4,10 TETRAHYDROPYRIMIDO[1,2 A]BENZIMIDAZOLE HYDROCHLORIDE; 9 (3,4 DIMETHOXYPHENACYL) 2,3 DIHYDROIMIDAZO[1,2 A]BENZIMIDAZOLE HYDROBROMIDE; 9 (3,5 DI TERT BUTYL 4 HYDROXYPHENACYL) 2,3 DIHYDROIMIDAZO[1,2 A]BENZIMIDAZOLE HYDROBROMIDE; 9 (4 HYDROXYPHENACYL) 2,3 DIHYDROIMIDAZO[1,2 A]BENZIMIDAZOLE HYDROBROMIDE; BENZIMIDAZOLE DERIVATIVE; CHLORPROPAMIDE; GLUCOSE; HYDROXYL GROUP; RADICAL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTIOXIDANT ACTIVITY; ARTICLE; BLOOD RHEOLOGY; CONTROLLED STUDY; DRUG ACTIVITY; DRUG SYNTHESIS; GLUCOSE BLOOD LEVEL; NONHUMAN; RAT;

EID: 35148872225     PISSN: 0091150X     EISSN: 15739031     Source Type: Journal    
DOI: 10.1007/s11094-007-0028-z     Document Type: Article

References (19)

1. Yu. P. Kozlov, Free Radicals and Their Role in Normal and Pathological Processes [in Russian], Moscow State University, Moscow (1973).
2. L. K. Obukhova and N. M. Emmanuel', Usp. Khim., 52(3), 353-372 (1983).
3. I. B. Afanas'ev, Khim.-Farm. Zh., 19(1), 11-23 (1985).
4. M. D. Mashkovskii, Drugs [in Russian], Novaya Volna, Moscow (2000), pp. 291-299, 363-371.
5. I. A. Degterev and G. E. Zaikov, Khim.-Farm. Zh., 22(8), 910-919 (1988).
6. A. D. Durnev and S. B. Serfedenin, Khim.-Farm. Zh., 24(2), 92-100 (1990).
7. V. A. Anisimova, I. E. Tolpygun, A. A. Spasov, et al., Khim.-Farm. Zh., 40(9), 23-26 (2006).
8. L. C. King and G. K. Ostrum, J. Org. Chem., 29, 3459 (1964).
9. C. J. Sharpe and R. S. Shadbolt, J. Med. Chem., 14(10), 977-982 (1971).
10. V. A. Anisimova, A. A. Spasov, V. A. Kosolapov, et al., Khim.-Farm. Zh., 39(9), 26-32 (2005).
11. N. V. Portnykh, A. A. Volod'kin, and V. V. Ershov, Izv. Akad. Nauk SSSR, Ser. Khim., No. 12, 2243-2244 (1966).
12. A. A. Volod'kin, V. V. Ershov, and N. V. Portnykh, Izv. Akad. Nauk SSSR, Ser. Khim., No. 3, 752 (1966).
13. V. V. Ershov, G. A. Nikiforov, and A. A. Volod'kin, Spatially-Constrained Phenols [in Russian], Khimiya, Moscow (1972), pp. 290-296.
14. A. F. Pozharskii, V. A. Anisimova, and E. B. Tsupak, Practical Works on the Chemistry of Heterocycles [in Russian], Rostov University, Rostov-on-Don (1988), pp. 124-125.
15. G. Holland, D. Jaeger, R. Wagner, et al., J. Med. Pharm. Chem., 3, 99 (1961).
16. M. B. Plotnikov, A. A. Koltunov, and O. I. Aliev, Eksp. Klin. Farmakol., 59(6), 54-55 (1996).
17. N. A. Dobrovol'skii, Yu. M. Lopukhin, A. S. Parfenov, et al., in: Rheological Investigations in Medicine (A Collection of Papers) [in Russian], Moscow (1998), pp. 45-51.
18. A. D. Vikulov and I. A. Osetrov, Fiziol. Chel., No. 5, 24-132 (2001).
19. A. I. Venchikov and V. A. Venchikov, The Main Methods of Statistical Data Processing in Physiology [in Russian], Meditsina, Moscow (1974), p. 152.