Synthesis and anticancer activity of some novel 2-substituted benzimidazole derivatives

European Journal of Medicinal Chemistry

Volumn 45, Issue 7, 2010, Pages 2949-2956

  Refaat, Hanan M ^a  

^a CAIRO UNIVERSITY   (Egypt)

Author keywords

Anticancer; Cycloalkylidenecyanomethylbenzimidazoles; Fluorobenzylidenecyanomethylbenzimidazoles; Oxothiazolidinylidenecyanomethyl benzimidazoles; Oxothiazolidinylidenemethylbenzimidazole; Thiazinylidenecyanomethylbenzimidazoles; Thiazolylidenecyanomethyl benzimidazoles; Thioxothiazolylbenzimidazoles

Indexed keywords

2 (4 AMINO 3 BENZYL 2 THIOXO 2,3 DIHYDROTHIAZOL 5 YL)BENZIMIDAZOLE 5 CARBOXYLIC ACID; 2 (4 AMINO 3 PHENYL 2 THIOXO 2,3 DIHYDROTHIAZOL 5 YL)BENZIMIDAZOLE 5 CARBOXYLIC ACID; 2 (4 OXOTHIAZOLIDIN 2 YLIDENE)METHYLBENZIMIDAZOLE 5 CARBOXYLIC ACID; 2 [(3 CYCLOHEXYL 4 OXOTHIAZOLIDIN 2 YLIDENE)CYANOMETHYL]BENZIMIDAZOLE 5 CARBOXYLIC ACID; 2 [(3 PHENYL 5 OXOTHIAZOLIDIN 2 YLIDENE)CYANOMETHYL]BENZIMIDAZOLE 5 CARBOXYLIC ACID; 2 [(3 PHENYL[1,3]THIAZIN 2 YLIDENE)CYANOMETHYL]BENZIMIDAZOLE 5 CARBOXYLIC ACID; 2 [(4 (4 BROMOPHENYL) 3 CYCLOHEXYLTHIAZOL 2 YLIDENE)CYANOMETHYL METHYL]BENZAMIDAZOLE 5 CARBOXYLIC ACID; 2 [(4 FLUOROBENZYLIDENE)CYANOMETHYL]BENZIMIDAZOLE 5 CARBOXYLIC ACID; 2 [(CYCLOHEXYLIDENE)CYANOMETHYL]BENZIMIDAZOLE 5 CARBOXYLIC ACID; 2 [3 (4 BROMOPHENYL) 4 (2 METHOXYPHENYLTHIAZOL 2 YLIDENE)CYANOMETHYL]BENZIMIDAZOLE 5 CARBOXYLIC ACID; 5 CHLORO 2 [(3 PHENYL 4 (4 CHLOROPHENYL)THIAZOL 2 YLIDENE)CYANOMETHYL]BENZIMIDAZOLE; 5 CHLORO 2 [(3 PHENYL 4 OXOTHIAZOLIDIN 2 YLIDENE)CYANOMETHYL]BENZIMIDAZOLE; 5 CHLORO 2 [(3 PHENYL[1,3]THIAZIN 2 YLIDENE)CYANOMETHYL]BENZIMIDAZOLE; 5 CHLORO 2 [(4 FLUOROBENZYLIDENE)CYANOMETHYL]BENZIMIDAZOLE; 5 CHLORO 2 [(CYCLOPENTYLIDENE)CYANOMETHYL]BENZIMIDAZOLE; BENZIMIDAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL STRAIN HCT116; CELL STRAIN HEPG2; CELL STRAIN MCF 7; DRUG SCREENING; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IN VITRO STUDY;

ANTINEOPLASTIC AGENTS; BENZIMIDAZOLES; CELL LINE, TUMOR; HUMANS; INHIBITORY CONCENTRATION 50;

EID: 77954349595     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2010.03.022     Document Type: Article

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