cGAS-cGAMP-STING: The three musketeers of cytosolic DNA sensing and signaling

IUBMB Life

Volumn 68, Issue 11, 2016, Pages 858-870

  Tao, Jianli ^a,b,c   Zhou, Xiang ^a,b,c   Jiang, Zhengfan ^a,b,c  

^a PEKING UNIVERSITY   (China)

^b Peking University   (China)

^c Tsinghua University   (China)

Author keywords

cancer; cGAMP; cGAS; infection; inflammation; STING; type I IFNs

Indexed keywords

ADENOSINE PHOSPHATE; AMP SYNTHASE; CYCLIC GMP; DNA; MEMBRANE PROTEIN; STIMULATOR OF INTERFERON GENE PROTEIN; SYNTHETASE; UNCLASSIFIED DRUG; CYCLIC GUANOSINE MONOPHOSPHATE-ADENOSINE MONOPHOSPHATE; CYCLIC NUCLEOTIDE; MB21D1 PROTEIN, HUMAN; MPYS PROTEIN, HUMAN; NUCLEOTIDYLTRANSFERASE;

DNA VIRUS INFECTION; GRAM NEGATIVE INFECTION; GRAM POSITIVE INFECTION; HOST PATHOGEN INTERACTION; HUMAN; INFLAMMATION; INNATE IMMUNITY; INTERACTIONS WITH DNA; NEOPLASM; NONHUMAN; PROTEIN FUNCTION; REVIEW; SECOND MESSENGER; SIGNAL TRANSDUCTION; ANIMAL; GENE EXPRESSION REGULATION; IMMUNOLOGY; PHYSIOLOGY;

ANIMALS; GENE EXPRESSION REGULATION; HUMANS; IMMUNITY, INNATE; MEMBRANE PROTEINS; NUCLEOTIDES, CYCLIC; NUCLEOTIDYLTRANSFERASES; SIGNAL TRANSDUCTION;

EID: 84992580431     PISSN: 15216543     EISSN: 15216551     Source Type: Journal    
DOI: 10.1002/iub.1566     Document Type: Review

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