Crosstalk between the cGAS DNA sensor and beclin-1 autophagy protein shapes innate antimicrobial immune responses

Cell Host and Microbe

Volumn 15, Issue 2, 2014, Pages 228-238

  Liang, Qiming ^a   Seo, Gil Ju ^a   Choi, Youn Jung ^a   Kwak, Mi Jeong ^b   Ge, Jianning ^a   Rodgers, Mary A ^a   Shi, Mude ^a   Leslie, Benjamin J ^c,d   Hopfner, Karl Peter ^e   Ha, Taekjip ^c,d   Oh, Byung Ha ^b   Jung, Jae U ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

^c University of Illinois at Urbana Champaign   (United States)

^d HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^e UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BECLIN 1; CYCLIC AMP; CYCLIC GMP; CYCLIC GMP AMP SYNTHETASE; DNA; DOUBLE STRANDED DNA; INTERFERON; PHOSPHATIDYLINOSITOL 3 KINASE; STIMULATOR OF INTERFERON GENE; SYNTHETASE; UNCLASSIFIED DRUG; BETA INTERFERON; MESSENGER RNA; SINGLE STRANDED DNA;

ANIMAL CELL; ARTICLE; AUTOPHAGY; CONTROLLED STUDY; DNA DEGRADATION; ENZYME ACTIVITY; HERPES SIMPLEX; HERPES SIMPLEX VIRUS 1; HUMAN; HUMAN CELL; IMMUNOSTIMULATION; INNATE IMMUNITY; INTERFERON PRODUCTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; ANTIMICROBIAL ACTIVITY; AUTOPHAGOSOME; BINDING AFFINITY; BIOSENSOR; BIOSYNTHESIS; BONE MARROW DERIVED MACROPHAGE; ENDOCYTOSIS; GEL FILTRATION CHROMATOGRAPHY; L929 CELL LINE; PROTEIN DNA BINDING; VIRUS MUTANT; VIRUS REPLICATION;

ANIMALS; APOPTOSIS REGULATORY PROTEINS; AUTOPHAGY; CELL LINE; DNA; HERPESVIRUS 1, HUMAN; HUMANS; IMMUNITY, INNATE; INTERFERONS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MEMBRANE PROTEINS; MICE; NUCLEOTIDES, CYCLIC; NUCLEOTIDYLTRANSFERASES; PHOSPHATIDYLINOSITOL 3-KINASE;

HUMAN HERPESVIRUS 1;

EID: 84893912159     PISSN: 19313128     EISSN: 19346069     Source Type: Journal    
DOI: 10.1016/j.chom.2014.01.009     Document Type: Article

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