cGAS Senses Human Cytomegalovirus and Induces Type I Interferon Responses in Human Monocyte-Derived Cells

PLoS Pathogens

Volumn 12, Issue 4, 2016, Pages

  Paijo, Jennifer ^a   Döring, Marius ^a   Spanier, Julia ^a   Grabski, Elena ^a   Nooruzzaman, Mohammed ^a   Schmidt, Tobias ^b   Witte, Gregor ^c   Messerle, Martin ^d   Hornung, Veit ^b,c   Kaever, Volkhard ^d   Kalinke, Ulrich ^a  

^a INSTITUTE OF INFECTION IMMUNOLOGY   (Germany)

^b UNIVERSITY HOSPITAL BONN   (Germany)

^c UNIVERSITY OF MUNICH   (Germany)

^d HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; ALPHA INTERFERON; ALPHA2B INTERFERON; CRISPR ASSOCIATED PROTEIN; CYCLIC AMP SYNTHASE; CYCLIC GMP DERIVATIVE; CYCLIC GMP SYNTHASE; HUMAN INTERFERON; MESSENGER RNA; TOLL LIKE RECEPTOR 9; TYPE I INTERFERON; UNCLASSIFIED DRUG; VIRUS DNA; INTERFERON; MB21D1 PROTEIN, HUMAN; NUCLEOTIDYLTRANSFERASE; SMALL INTERFERING RNA;

ARTICLE; CELL DIFFERENTIATION; CELL ISOLATION; CELL STIMULATION; COMPARATIVE STUDY; CONTROLLED STUDY; CYTOMEGALOVIRUS INFECTION; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; GENE; GENE EXPRESSION; GENETIC TRANSFECTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; HUMAN CYTOMEGALOVIRUS; IMMUNE RESPONSE; MACROPHAGE; MASS SPECTROMETRY; MONOCYTE CULTURE; MRNA EXPRESSION ASSAY; PLASMACYTOID DENDRITIC CELL; POLYMERASE CHAIN REACTION; STIMULATOR OF INTERFERON GENE; WESTERN BLOTTING; BIOSYNTHESIS; IMMUNOBLOTTING; IMMUNOLOGY; MONOCYTE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TANDEM MASS SPECTROMETRY; VIROLOGY;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYTOMEGALOVIRUS INFECTIONS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; HUMANS; IMMUNOBLOTTING; INTERFERON TYPE I; MONOCYTES; NUCLEOTIDYLTRANSFERASES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING; TANDEM MASS SPECTROMETRY; TRANSFECTION;

EID: 84964850345     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1005546     Document Type: Article

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