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Volumn 112, Issue 42, 2015, Pages 12903-12904

CGMP-AMP synthase paves the way to autoimmunity

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; ADENOSINE MONOPHOSPHATE SYNTHASE; ADENOSINE PHOSPHATE; CELL NUCLEUS DNA; CYCLIC GMP; DNA; DNA TOPOISOMERASE; ENDONUCLEASE; EXTRACHROMOSOMAL DNA; INTERFERON; INTERFERON REGULATORY FACTOR 3; NUCLEIC ACID; SYNTHETASE; TOLL LIKE RECEPTOR; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; VIRUS DNA; NUCLEOTIDYLTRANSFERASE;

EID: 84947241868     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1517578112     Document Type: Article
Times cited : (5)

References (20)
  • 1
    • 33748455338 scopus 로고    scopus 로고
    • Type i interferons in host defense
    • Stetson DB, Medzhitov R (2006) Type I interferons in host defense. Immunity 25(3):373-381.
    • (2006) Immunity , vol.25 , Issue.3 , pp. 373-381
    • Stetson, D.B.1    Medzhitov, R.2
  • 2
    • 27944453599 scopus 로고    scopus 로고
    • Toll-like receptor-independent gene induction program activated by mammalian DNA escaped from apoptotic DNA degradation
    • Okabe Y, Kawane K, Akira S, Taniguchi T, Nagata S (2005) Toll-like receptor-independent gene induction program activated by mammalian DNA escaped from apoptotic DNA degradation. J Exp Med 202(10):1333-1339.
    • (2005) J Exp Med , vol.202 , Issue.10 , pp. 1333-1339
    • Okabe, Y.1    Kawane, K.2    Akira, S.3    Taniguchi, T.4    Nagata, S.5
  • 3
    • 29244471275 scopus 로고    scopus 로고
    • A Toll-like receptor-independent antiviral response induced by double-stranded B-form DNA
    • Ishii KJ, et al. (2006) A Toll-like receptor-independent antiviral response induced by double-stranded B-form DNA. Nat Immunol 7(1):40-48.
    • (2006) Nat Immunol , vol.7 , Issue.1 , pp. 40-48
    • Ishii, K.J.1
  • 5
    • 84873724533 scopus 로고    scopus 로고
    • Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA
    • Wu J, et al. (2013) Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA. Science 339(6121):826-830.
    • (2013) Science , vol.339 , Issue.6121 , pp. 826-830
    • Wu, J.1
  • 6
    • 84873711885 scopus 로고    scopus 로고
    • Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type i interferon pathway
    • Sun L, Wu J, Du F, Chen X, Chen ZJ (2013) Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway. Science 339(6121):786-791.
    • (2013) Science , vol.339 , Issue.6121 , pp. 786-791
    • Sun, L.1    Wu, J.2    Du, F.3    Chen, X.4    Chen, Z.J.5
  • 7
    • 0014690918 scopus 로고
    • Properties of deoxyribonuclease 3 from mammalian tissues
    • Lindahl T, Gally JA, Edelman GM (1969) Properties of deoxyribonuclease 3 from mammalian tissues. J Biol Chem 244(18): 5014-5019.
    • (1969) J Biol Chem , vol.244 , Issue.18 , pp. 5014-5019
    • Lindahl, T.1    Gally, J.A.2    Edelman, G.M.3
  • 8
    • 84925501444 scopus 로고    scopus 로고
    • Human disease phenotypes associated with mutations in TREX1
    • Rice GI, Rodero MP, Crow YJ (2015) Human disease phenotypes associated with mutations in TREX1. J Clin Immunol 35(3):235-243.
    • (2015) J Clin Immunol , vol.35 , Issue.3 , pp. 235-243
    • Rice, G.I.1    Rodero, M.P.2    Crow, Y.J.3
  • 9
    • 49549100511 scopus 로고    scopus 로고
    • Trex1 prevents cell-intrinsic initiation of autoimmunity
    • Stetson DB, Ko JS, Heidmann T, Medzhitov R (2008) Trex1 prevents cell-intrinsic initiation of autoimmunity. Cell 134(4):587-598.
    • (2008) Cell , vol.134 , Issue.4 , pp. 587-598
    • Stetson, D.B.1    Ko, J.S.2    Heidmann, T.3    Medzhitov, R.4
  • 10
    • 43249122205 scopus 로고    scopus 로고
    • The functions of Deoxyribonuclease II in immunity and development
    • Liu MF, et al. (2008) The functions of Deoxyribonuclease II in immunity and development. DNA Cell Biol 27(5):223-228.
    • (2008) DNA Cell Biol , vol.27 , Issue.5 , pp. 223-228
    • Liu, M.F.1
  • 11
    • 12344290452 scopus 로고    scopus 로고
    • Lethal anemia caused by interferon-beta produced in mouse embryos carrying undigested DNA
    • Yoshida H, Okabe Y, Kawane K, Fukuyama H, Nagata S (2005) Lethal anemia caused by interferon-beta produced in mouse embryos carrying undigested DNA. Nat Immunol 6(1):49-56.
    • (2005) Nat Immunol , vol.6 , Issue.1 , pp. 49-56
    • Yoshida, H.1    Okabe, Y.2    Kawane, K.3    Fukuyama, H.4    Nagata, S.5
  • 12
    • 33750465224 scopus 로고    scopus 로고
    • Chronic polyarthritis caused by mammalian DNA that escapes from degradation in macrophages
    • Kawane K, et al. (2006) Chronic polyarthritis caused by mammalian DNA that escapes from degradation in macrophages. Nature 443(7114):998-1002.
    • (2006) Nature , vol.443 , Issue.7114 , pp. 998-1002
    • Kawane, K.1
  • 13
    • 84947245185 scopus 로고    scopus 로고
    • Activation of cyclic GMP-AMP synthase by self-DNA causes autoimmune diseases
    • Gao D, et al. (2015) Activation of cyclic GMP-AMP synthase by self-DNA causes autoimmune diseases. Proc Natl Acad Sci USA 112:E5699-E5705.
    • (2015) Proc Natl Acad Sci USA , vol.112 , pp. E5699-E5705
    • Gao, D.1
  • 14
    • 84856301080 scopus 로고    scopus 로고
    • Autoimmunity initiates in nonhematopoietic cells and progresses via lymphocytes in an interferon-dependent autoimmune disease
    • Gall A, et al. (2012) Autoimmunity initiates in nonhematopoietic cells and progresses via lymphocytes in an interferon-dependent autoimmune disease. Immunity 36(1):120-131.
    • (2012) Immunity , vol.36 , Issue.1 , pp. 120-131
    • Gall, A.1
  • 15
    • 84869794842 scopus 로고    scopus 로고
    • STING manifests self DNA-dependent inflammatory disease
    • Ahn J, Gutman D, Saijo S, Barber GN (2012) STING manifests self DNA-dependent inflammatory disease. Proc Natl Acad Sci USA 109(47):19386-19391.
    • (2012) Proc Natl Acad Sci USA , vol.109 , Issue.47 , pp. 19386-19391
    • Ahn, J.1    Gutman, D.2    Saijo, S.3    Barber, G.N.4
  • 16
    • 84908680759 scopus 로고    scopus 로고
    • Type i interferonopathies: Mendelian type i interferon up-regulation
    • Crow YJ (2015) Type I interferonopathies: Mendelian type I interferon up-regulation. Curr Opin Immunol 32:7-12.
    • (2015) Curr Opin Immunol , vol.32 , pp. 7-12
    • Crow, Y.J.1
  • 17
    • 34548327158 scopus 로고    scopus 로고
    • Mutations in the gene encoding the 3′-5′ DNA exonuclease TREX1 are associated with systemic lupus erythematosus
    • Lee-Kirsch MA, et al. (2007) Mutations in the gene encoding the 3′-5′ DNA exonuclease TREX1 are associated with systemic lupus erythematosus. Nat Genet 39(9):1065-1067.
    • (2007) Nat Genet , vol.39 , Issue.9 , pp. 1065-1067
    • Lee-Kirsch, M.A.1
  • 18
    • 79958015275 scopus 로고    scopus 로고
    • Evaluation of the TREX1 gene in a large multi-ancestral lupus cohort
    • Namjou B, et al. (2011) Evaluation of the TREX1 gene in a large multi-ancestral lupus cohort. Genes Immun 12(4):270-279.
    • (2011) Genes Immun , vol.12 , Issue.4 , pp. 270-279
    • Namjou, B.1
  • 19
    • 84910040154 scopus 로고    scopus 로고
    • Self-DNA, STING-dependent signaling and the origins of autoinflammatory disease
    • Ahn J, Barber GN (2014) Self-DNA, STING-dependent signaling and the origins of autoinflammatory disease. Curr Opin Immunol 31:121-126.
    • (2014) Curr Opin Immunol , vol.31 , pp. 121-126
    • Ahn, J.1    Barber, G.N.2
  • 20
    • 84940121945 scopus 로고    scopus 로고
    • Cutting edge: CGAS is required for lethal autoimmune disease in the Trex1-deficient mouse model of Aicardi-Goutières Syndrome
    • Gray EE, Treuting PM, Woodward JJ, Stetson DB (2015) Cutting edge: cGAS is required for lethal autoimmune disease in the Trex1-deficient mouse model of Aicardi-Goutières Syndrome. J Immunol 195(5):1939-1943.
    • (2015) J Immunol , vol.195 , Issue.5 , pp. 1939-1943
    • Gray, E.E.1    Treuting, P.M.2    Woodward, J.J.3    Stetson, D.B.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.