-
1
-
-
33748455338
-
Type i interferons in host defense
-
Stetson DB, Medzhitov R (2006) Type I interferons in host defense. Immunity 25(3):373-381.
-
(2006)
Immunity
, vol.25
, Issue.3
, pp. 373-381
-
-
Stetson, D.B.1
Medzhitov, R.2
-
2
-
-
27944453599
-
Toll-like receptor-independent gene induction program activated by mammalian DNA escaped from apoptotic DNA degradation
-
Okabe Y, Kawane K, Akira S, Taniguchi T, Nagata S (2005) Toll-like receptor-independent gene induction program activated by mammalian DNA escaped from apoptotic DNA degradation. J Exp Med 202(10):1333-1339.
-
(2005)
J Exp Med
, vol.202
, Issue.10
, pp. 1333-1339
-
-
Okabe, Y.1
Kawane, K.2
Akira, S.3
Taniguchi, T.4
Nagata, S.5
-
3
-
-
29244471275
-
A Toll-like receptor-independent antiviral response induced by double-stranded B-form DNA
-
Ishii KJ, et al. (2006) A Toll-like receptor-independent antiviral response induced by double-stranded B-form DNA. Nat Immunol 7(1):40-48.
-
(2006)
Nat Immunol
, vol.7
, Issue.1
, pp. 40-48
-
-
Ishii, K.J.1
-
5
-
-
84873724533
-
Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA
-
Wu J, et al. (2013) Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA. Science 339(6121):826-830.
-
(2013)
Science
, vol.339
, Issue.6121
, pp. 826-830
-
-
Wu, J.1
-
6
-
-
84873711885
-
Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type i interferon pathway
-
Sun L, Wu J, Du F, Chen X, Chen ZJ (2013) Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway. Science 339(6121):786-791.
-
(2013)
Science
, vol.339
, Issue.6121
, pp. 786-791
-
-
Sun, L.1
Wu, J.2
Du, F.3
Chen, X.4
Chen, Z.J.5
-
7
-
-
0014690918
-
Properties of deoxyribonuclease 3 from mammalian tissues
-
Lindahl T, Gally JA, Edelman GM (1969) Properties of deoxyribonuclease 3 from mammalian tissues. J Biol Chem 244(18): 5014-5019.
-
(1969)
J Biol Chem
, vol.244
, Issue.18
, pp. 5014-5019
-
-
Lindahl, T.1
Gally, J.A.2
Edelman, G.M.3
-
8
-
-
84925501444
-
Human disease phenotypes associated with mutations in TREX1
-
Rice GI, Rodero MP, Crow YJ (2015) Human disease phenotypes associated with mutations in TREX1. J Clin Immunol 35(3):235-243.
-
(2015)
J Clin Immunol
, vol.35
, Issue.3
, pp. 235-243
-
-
Rice, G.I.1
Rodero, M.P.2
Crow, Y.J.3
-
9
-
-
49549100511
-
Trex1 prevents cell-intrinsic initiation of autoimmunity
-
Stetson DB, Ko JS, Heidmann T, Medzhitov R (2008) Trex1 prevents cell-intrinsic initiation of autoimmunity. Cell 134(4):587-598.
-
(2008)
Cell
, vol.134
, Issue.4
, pp. 587-598
-
-
Stetson, D.B.1
Ko, J.S.2
Heidmann, T.3
Medzhitov, R.4
-
10
-
-
43249122205
-
The functions of Deoxyribonuclease II in immunity and development
-
Liu MF, et al. (2008) The functions of Deoxyribonuclease II in immunity and development. DNA Cell Biol 27(5):223-228.
-
(2008)
DNA Cell Biol
, vol.27
, Issue.5
, pp. 223-228
-
-
Liu, M.F.1
-
11
-
-
12344290452
-
Lethal anemia caused by interferon-beta produced in mouse embryos carrying undigested DNA
-
Yoshida H, Okabe Y, Kawane K, Fukuyama H, Nagata S (2005) Lethal anemia caused by interferon-beta produced in mouse embryos carrying undigested DNA. Nat Immunol 6(1):49-56.
-
(2005)
Nat Immunol
, vol.6
, Issue.1
, pp. 49-56
-
-
Yoshida, H.1
Okabe, Y.2
Kawane, K.3
Fukuyama, H.4
Nagata, S.5
-
12
-
-
33750465224
-
Chronic polyarthritis caused by mammalian DNA that escapes from degradation in macrophages
-
Kawane K, et al. (2006) Chronic polyarthritis caused by mammalian DNA that escapes from degradation in macrophages. Nature 443(7114):998-1002.
-
(2006)
Nature
, vol.443
, Issue.7114
, pp. 998-1002
-
-
Kawane, K.1
-
13
-
-
84947245185
-
Activation of cyclic GMP-AMP synthase by self-DNA causes autoimmune diseases
-
Gao D, et al. (2015) Activation of cyclic GMP-AMP synthase by self-DNA causes autoimmune diseases. Proc Natl Acad Sci USA 112:E5699-E5705.
-
(2015)
Proc Natl Acad Sci USA
, vol.112
, pp. E5699-E5705
-
-
Gao, D.1
-
14
-
-
84856301080
-
Autoimmunity initiates in nonhematopoietic cells and progresses via lymphocytes in an interferon-dependent autoimmune disease
-
Gall A, et al. (2012) Autoimmunity initiates in nonhematopoietic cells and progresses via lymphocytes in an interferon-dependent autoimmune disease. Immunity 36(1):120-131.
-
(2012)
Immunity
, vol.36
, Issue.1
, pp. 120-131
-
-
Gall, A.1
-
15
-
-
84869794842
-
STING manifests self DNA-dependent inflammatory disease
-
Ahn J, Gutman D, Saijo S, Barber GN (2012) STING manifests self DNA-dependent inflammatory disease. Proc Natl Acad Sci USA 109(47):19386-19391.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, Issue.47
, pp. 19386-19391
-
-
Ahn, J.1
Gutman, D.2
Saijo, S.3
Barber, G.N.4
-
16
-
-
84908680759
-
Type i interferonopathies: Mendelian type i interferon up-regulation
-
Crow YJ (2015) Type I interferonopathies: Mendelian type I interferon up-regulation. Curr Opin Immunol 32:7-12.
-
(2015)
Curr Opin Immunol
, vol.32
, pp. 7-12
-
-
Crow, Y.J.1
-
17
-
-
34548327158
-
Mutations in the gene encoding the 3′-5′ DNA exonuclease TREX1 are associated with systemic lupus erythematosus
-
Lee-Kirsch MA, et al. (2007) Mutations in the gene encoding the 3′-5′ DNA exonuclease TREX1 are associated with systemic lupus erythematosus. Nat Genet 39(9):1065-1067.
-
(2007)
Nat Genet
, vol.39
, Issue.9
, pp. 1065-1067
-
-
Lee-Kirsch, M.A.1
-
18
-
-
79958015275
-
Evaluation of the TREX1 gene in a large multi-ancestral lupus cohort
-
Namjou B, et al. (2011) Evaluation of the TREX1 gene in a large multi-ancestral lupus cohort. Genes Immun 12(4):270-279.
-
(2011)
Genes Immun
, vol.12
, Issue.4
, pp. 270-279
-
-
Namjou, B.1
-
19
-
-
84910040154
-
Self-DNA, STING-dependent signaling and the origins of autoinflammatory disease
-
Ahn J, Barber GN (2014) Self-DNA, STING-dependent signaling and the origins of autoinflammatory disease. Curr Opin Immunol 31:121-126.
-
(2014)
Curr Opin Immunol
, vol.31
, pp. 121-126
-
-
Ahn, J.1
Barber, G.N.2
-
20
-
-
84940121945
-
Cutting edge: CGAS is required for lethal autoimmune disease in the Trex1-deficient mouse model of Aicardi-Goutières Syndrome
-
Gray EE, Treuting PM, Woodward JJ, Stetson DB (2015) Cutting edge: cGAS is required for lethal autoimmune disease in the Trex1-deficient mouse model of Aicardi-Goutières Syndrome. J Immunol 195(5):1939-1943.
-
(2015)
J Immunol
, vol.195
, Issue.5
, pp. 1939-1943
-
-
Gray, E.E.1
Treuting, P.M.2
Woodward, J.J.3
Stetson, D.B.4
|