The DNA Structure-Specific Endonuclease MUS81 Mediates DNA Sensor STING-Dependent Host Rejection of Prostate Cancer Cells

Immunity

Volumn 44, Issue 5, 2016, Pages 1177-1189

  Ho, Samantha S W ^a   Zhang, Wendy Y L ^a   Tan, Nikki Yi Jie ^a   Khatoo, Muznah ^a   Suter, Manuel A ^a   Tripathi, Shubhita ^a   Cheung, Florence S G ^a   Lim, Weng Khong ^b,c   Tan, Puay Hoon ^a,d   Ngeow, Joanne ^a,b,c   Gasser, Stephan ^a,e  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b DIVISION OF MEDICAL ONCOLOGY   (Singapore)

^c DUKE NUS MEDICAL SCHOOL   (Singapore)

^d SINGAPORE GENERAL HOSPITAL   (Singapore)

^e NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Cytosolic DNA; DNA repair; Endonuclease; Innate immunity; Prostate cancer

Indexed keywords

ENDONUCLEASE; ENDONUCLEASE MUS81; GAMMA INTERFERON; GENOMIC DNA; UNCLASSIFIED DRUG; AUTOANTIGEN; DNA; DNA BINDING PROTEIN; INTERFERON; MEMBRANE PROTEIN; MPYS PROTEIN, MOUSE; MUS81 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; B CELL LYMPHOMA CELL; BREAST CANCER; CANCER CELL; CANCER GROWTH; CANCER STAGING; CANCER TISSUE; CRISPR CAS SYSTEM; CYTOSOL; DNA PROBE; DNA REPAIR; DNA STRUCTURE; HOST CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; MACROPHAGE; MALE; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; PROSTATE CANCER; SIGNAL TRANSDUCTION; T LYMPHOCYTE; TUMOR REJECTION; ANIMAL; C57BL MOUSE; EXPERIMENTAL NEOPLASM; IMMUNOLOGY; KNOCKOUT MOUSE; LYMPHOCYTE ACTIVATION; METABOLISM; MOUSE; PATHOLOGY; PROSTATE TUMOR; TUMOR CELL LINE;

ANIMALS; AUTOANTIGENS; CELL LINE, TUMOR; DNA; DNA-BINDING PROTEINS; ENDONUCLEASES; HUMANS; INTERFERON TYPE I; LYMPHOCYTE ACTIVATION; MALE; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEOPLASM STAGING; NEOPLASMS, EXPERIMENTAL; PHAGOCYTOSIS; PROSTATIC NEOPLASMS; T-LYMPHOCYTES;

EID: 84966929800     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2016.04.010     Document Type: Article

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