A bacterial cyclic dinucleotide activates the cytosolic surveillance pathway and mediates innate resistance to tuberculosis

Nature Medicine

Volumn 21, Issue 4, 2015, Pages 401-408

  Dey, Bappaditya ^a,b   Dey, Ruchi Jain ^a   Cheung, Laurene S ^a   Pokkali, Supriya ^a,c   Guo, Haidan ^a   Lee, Jong Hee ^a   Bishai, William R ^a,b  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; BETA INTERFERON; CYTOKINE; DINUCLEOSIDE PHOSPHATE; GAMMA INTERFERON; LYASE; MB21D1 PROTEIN, MOUSE; NUCLEOTIDYLTRANSFERASE;

ANIMAL; AUTOPHAGY; BAGG ALBINO MOUSE; C57BL MOUSE; CYTOSOL; FEMALE; GENETIC COMPLEMENTATION; MACROPHAGE; METABOLISM; MOUSE; MYCOBACTERIUM TUBERCULOSIS; SIGNAL TRANSDUCTION; TUBERCULOSIS; VIRULENCE;

ANIMALS; AUTOPHAGY; BACTERIAL PROTEINS; CYTOKINES; CYTOSOL; DINUCLEOSIDE PHOSPHATES; FEMALE; GENETIC COMPLEMENTATION TEST; INTERFERON-BETA; INTERFERON-GAMMA; MACROPHAGES; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MYCOBACTERIUM TUBERCULOSIS; NUCLEOTIDYLTRANSFERASES; PHOSPHORUS-OXYGEN LYASES; SIGNAL TRANSDUCTION; TUBERCULOSIS; VIRULENCE;

EID: 84940000532     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.3813     Document Type: Article

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