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Volumn 428, Issue 17, 2016, Pages 3372-3386

For Better or Worse: Cytosolic DNA Sensing during Intracellular Bacterial Infection Induces Potent Innate Immune Responses

Author keywords

cytosolic DNA sensing; host pathogen interactions; innate immunity; intracellular bacteria; type I interferon

Indexed keywords

AIM2 PROTEIN; BACTERIAL DNA; INFLAMMASOME; INTERFERON; UNCLASSIFIED DRUG; IMMUNOGLOBULIN RECEPTOR;

EID: 84965047199     PISSN: 00222836     EISSN: 10898638     Source Type: Journal    
DOI: 10.1016/j.jmb.2016.04.030     Document Type: Review
Times cited : (17)

References (121)
  • 1
    • 10944253145 scopus 로고    scopus 로고
    • Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages
    • [1] Gutierrez, M.G., Master, S.S., Singh, S.B., Taylor, G.A., Colombo, M.I., Deretic, V., Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages. Cell. 119 (2004), 753–766, 10.1016/j.cell.2004.11.038.
    • (2004) Cell. , vol.119 , pp. 753-766
    • Gutierrez, M.G.1    Master, S.S.2    Singh, S.B.3    Taylor, G.A.4    Colombo, M.I.5    Deretic, V.6
  • 2
    • 84865220380 scopus 로고    scopus 로고
    • Extracellular M. Tuberculosis DNA targets bacteria for autophagy by activating the host DNA-sensing pathway
    • [2] Watson, R.O., Manzanillo, P.S., Cox, J.S., Extracellular M. Tuberculosis DNA targets bacteria for autophagy by activating the host DNA-sensing pathway. Cell 150 (2012), 803–815, 10.1016/j.cell.2012.06.040.
    • (2012) Cell , vol.150 , pp. 803-815
    • Watson, R.O.1    Manzanillo, P.S.2    Cox, J.S.3
  • 3
    • 84906088413 scopus 로고    scopus 로고
    • Type I IFN signaling triggers immunopathology in tuberculosis-susceptible mice by modulating lung phagocyte dynamics
    • [3] Dorhoi, A., Yeremeev, V., Nouailles, G., Weiner, J., Jörg, S., Heinemann, E., et al., Type I IFN signaling triggers immunopathology in tuberculosis-susceptible mice by modulating lung phagocyte dynamics. Eur. J. Immunol. 44 (2014), 2380–2393, 10.1002/eji.201344219.
    • (2014) Eur. J. Immunol. , vol.44 , pp. 2380-2393
    • Dorhoi, A.1    Yeremeev, V.2    Nouailles, G.3    Weiner, J.4    Jörg, S.5    Heinemann, E.6
  • 4
    • 77955894773 scopus 로고    scopus 로고
    • An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis
    • [4] Berry, M.P.R., Graham, C.M., McNab, F.W., Xu, Z., Bloch, S.A.A., Oni, T., et al., An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis. Nature. 466 (2010), 973–977, 10.1038/nature09247.
    • (2010) Nature. , vol.466 , pp. 973-977
    • Berry, M.P.R.1    Graham, C.M.2    McNab, F.W.3    Xu, Z.4    Bloch, S.A.A.5    Oni, T.6
  • 5
    • 77951782290 scopus 로고    scopus 로고
    • Intranasal Poly-IC treatment exacerbates tuberculosis in mice through the pulmonary recruitment of a pathogen-permissive monocyte/macrophage population
    • [5] Antonelli, L.R.V., Gigliotti Rothfuchs, A., Gonçalves, R., Roffê, E., Cheever, A.W., Bafica, A., et al., Intranasal Poly-IC treatment exacerbates tuberculosis in mice through the pulmonary recruitment of a pathogen-permissive monocyte/macrophage population. J. Clin. Invest. 120 (2010), 1674–1682, 10.1172/JCI40817.
    • (2010) J. Clin. Invest. , vol.120 , pp. 1674-1682
    • Antonelli, L.R.V.1    Gigliotti Rothfuchs, A.2    Gonçalves, R.3    Roffê, E.4    Cheever, A.W.5    Bafica, A.6
  • 6
    • 0034619794 scopus 로고    scopus 로고
    • A Toll-like receptor recognizes bacterial DNA
    • [6] Hemmi, H., Takeuchi, O., Kawai, T., Kaisho, T., Sato, S., Sanjo, H., et al., A Toll-like receptor recognizes bacterial DNA. Nature. 408 (2000), 740–745, 10.1038/35047123.
    • (2000) Nature. , vol.408 , pp. 740-745
    • Hemmi, H.1    Takeuchi, O.2    Kawai, T.3    Kaisho, T.4    Sato, S.5    Sanjo, H.6
  • 7
    • 47249083830 scopus 로고    scopus 로고
    • Functional characterization of murine interferon regulatory factor 5 (IRF-5) and its role in the innate antiviral response
    • [7] Paun, A., Reinert, J.T., Jiang, Z., Medin, C., Balkhi, M.Y., Fitzgerald, K.A., et al., Functional characterization of murine interferon regulatory factor 5 (IRF-5) and its role in the innate antiviral response. J. Biol. Chem. 283 (2008), 14,295–14,308, 10.1074/jbc.M800501200.
    • (2008) J. Biol. Chem. , vol.283 , pp. 14295-14308
    • Paun, A.1    Reinert, J.T.2    Jiang, Z.3    Medin, C.4    Balkhi, M.Y.5    Fitzgerald, K.A.6
  • 8
    • 23944516870 scopus 로고    scopus 로고
    • The host type I interferon response to viral and bacterial infections
    • [8] Perry, A.K., Chen, G., Zheng, D., Tang, H., Cheng, G., The host type I interferon response to viral and bacterial infections. Cell Res. 15 (2005), 407–422, 10.1038/sj.cr.7290309.
    • (2005) Cell Res. , vol.15 , pp. 407-422
    • Perry, A.K.1    Chen, G.2    Zheng, D.3    Tang, H.4    Cheng, G.5
  • 9
    • 0036318851 scopus 로고    scopus 로고
    • Bacterial CpG-DNA and lipopolysaccharides activate toll-like receptors at distinct cellular compartments
    • [9] Ahmad-Nejad, P., Häcker, H., Rutz, M., Bauer, S., Vabulas, R.M., Wagner, H., Bacterial CpG-DNA and lipopolysaccharides activate toll-like receptors at distinct cellular compartments. Eur. J. Immunol. 32 (2002), 1958–1968, 10.1002/1521-4141(200207)32:7<1958::AID-IMMU1958>3.0.CO;2-U.
    • (2002) Eur. J. Immunol. , vol.32 , pp. 1958-1968
    • Ahmad-Nejad, P.1    Häcker, H.2    Rutz, M.3    Bauer, S.4    Vabulas, R.M.5    Wagner, H.6
  • 10
    • 10344252795 scopus 로고    scopus 로고
    • IFN regulatory factor 3-dependent induction of type I IFNs by intracellular bacteria is mediated by a TLR- and Nod2-independent mechanism
    • [10] Stockinger, S., Reutterer, B., Schaljo, B., Schellack, C., Brunner, S., Materna, T., et al., IFN regulatory factor 3-dependent induction of type I IFNs by intracellular bacteria is mediated by a TLR- and Nod2-independent mechanism. J. Immunol. 173 (2004), 7416–7425.
    • (2004) J. Immunol. , vol.173 , pp. 7416-7425
    • Stockinger, S.1    Reutterer, B.2    Schaljo, B.3    Schellack, C.4    Brunner, S.5    Materna, T.6
  • 11
    • 30444450839 scopus 로고    scopus 로고
    • Recognition of cytosolic DNA activates an IRF3-dependent innate immune response
    • [11] Stetson, D.B., Medzhitov, R., Recognition of cytosolic DNA activates an IRF3-dependent innate immune response. Immunity 24 (2006), 93–103, 10.1016/j.immuni.2005.12.003.
    • (2006) Immunity , vol.24 , pp. 93-103
    • Stetson, D.B.1    Medzhitov, R.2
  • 12
    • 0030829372 scopus 로고    scopus 로고
    • Listeria monocytogenes infection of P388D1 macrophages results in a biphasic NF-kappaB (RelA/p50) activation induced by lipoteichoic acid and bacterial phospholipases and mediated by IkappaBalpha and IkappaBbeta degradation
    • [12] Hauf, N., Goebel, W., Fiedler, F., Sokolovic, Z., Kuhn, M., Listeria monocytogenes infection of P388D1 macrophages results in a biphasic NF-kappaB (RelA/p50) activation induced by lipoteichoic acid and bacterial phospholipases and mediated by IkappaBalpha and IkappaBbeta degradation. Proc. Natl. Acad. Sci. U.S.A. 94 (1997), 9394–9399.
    • (1997) Proc. Natl. Acad. Sci. U.S.A. , vol.94 , pp. 9394-9399
    • Hauf, N.1    Goebel, W.2    Fiedler, F.3    Sokolovic, Z.4    Kuhn, M.5
  • 13
    • 0037108761 scopus 로고    scopus 로고
    • Innate recognition of bacteria by a macrophage cytosolic surveillance pathway
    • [13] O'Riordan, M., Yi, C.H., Gonzales, R., Lee, K.-D., Portnoy, D.A., Innate recognition of bacteria by a macrophage cytosolic surveillance pathway. Proc. Natl. Acad. Sci. U.S.A. 99 (2002), 13,861–13,866, 10.1073/pnas.202476699.
    • (2002) Proc. Natl. Acad. Sci. U.S.A. , vol.99 , pp. 13861-13866
    • O'Riordan, M.1    Yi, C.H.2    Gonzales, R.3    Lee, K.-D.4    Portnoy, D.A.5
  • 14
    • 53349178089 scopus 로고    scopus 로고
    • STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling
    • [14] Ishikawa, H., Barber, G.N., STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling. Nature. 455 (2008), 674–678, 10.1038/nature07317.
    • (2008) Nature. , vol.455 , pp. 674-678
    • Ishikawa, H.1    Barber, G.N.2
  • 15
    • 70349943834 scopus 로고    scopus 로고
    • STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity
    • [15] Ishikawa, H., Ma, Z., Barber, G.N., STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity. Nature. 461 (2009), 788–792, 10.1038/nature08476.
    • (2009) Nature. , vol.461 , pp. 788-792
    • Ishikawa, H.1    Ma, Z.2    Barber, G.N.3
  • 16
    • 84863726252 scopus 로고    scopus 로고
    • Structure of STING bound to cyclic di-GMP reveals the mechanism of cyclic dinucleotide recognition by the immune system
    • [16] Shu, C., Yi, G., Watts, T., Kao, C.C., Li, P., Structure of STING bound to cyclic di-GMP reveals the mechanism of cyclic dinucleotide recognition by the immune system. Nat. Struct. Mol. Biol. 19 (2012), 722–724, 10.1038/nsmb.2331.
    • (2012) Nat. Struct. Mol. Biol. , vol.19 , pp. 722-724
    • Shu, C.1    Yi, G.2    Watts, T.3    Kao, C.C.4    Li, P.5
  • 17
    • 0032481352 scopus 로고    scopus 로고
    • Direct triggering of the type I interferon system by virus infection: activation of a transcription factor complex containing IRF-3 and CBP/p300
    • [17] Yoneyama, M., Suhara, W., Fukuhara, Y., Fukuda, M., Nishida, E., Fujita, T., Direct triggering of the type I interferon system by virus infection: activation of a transcription factor complex containing IRF-3 and CBP/p300. EMBO J. 17 (1998), 1087–1095, 10.1093/emboj/17.4.1087.
    • (1998) EMBO J. , vol.17 , pp. 1087-1095
    • Yoneyama, M.1    Suhara, W.2    Fukuhara, Y.3    Fukuda, M.4    Nishida, E.5    Fujita, T.6
  • 18
    • 82955187705 scopus 로고    scopus 로고
    • Interferon-stimulated genes and their antiviral effector functions
    • [18] Schoggins, J.W., Rice, C.M., Interferon-stimulated genes and their antiviral effector functions. Curr. Opin. Virol. 1 (2011), 519–525, 10.1016/j.coviro.2011.10.008.
    • (2011) Curr. Opin. Virol. , vol.1 , pp. 519-525
    • Schoggins, J.W.1    Rice, C.M.2
  • 19
    • 34247341367 scopus 로고    scopus 로고
    • TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity
    • [19] Gack, M.U., Shin, Y.C., Joo, C.-H., Urano, T., Liang, C., Sun, L., et al., TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity. Nature. 446 (2007), 916–920, 10.1038/nature05732.
    • (2007) Nature. , vol.446 , pp. 916-920
    • Gack, M.U.1    Shin, Y.C.2    Joo, C.-H.3    Urano, T.4    Liang, C.5    Sun, L.6
  • 20
  • 21
    • 34547143110 scopus 로고    scopus 로고
    • DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response
    • [21] Takaoka, A., Wang, Z., Choi, M.K., Yanai, H., Negishi, H., Ban, T., et al., DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response. Nature. 448 (2007), 501–505, 10.1038/nature06013.
    • (2007) Nature. , vol.448 , pp. 501-505
    • Takaoka, A.1    Wang, Z.2    Choi, M.K.3    Yanai, H.4    Negishi, H.5    Ban, T.6
  • 22
    • 80052969639 scopus 로고    scopus 로고
    • The helicase DDX41 senses intracellular DNA mediated by the adaptor STING in dendritic cells
    • [22] Zhang, Z., Yuan, B., Bao, M., Lu, N., Kim, T., Liu, Y.-J., The helicase DDX41 senses intracellular DNA mediated by the adaptor STING in dendritic cells. Nat. Immunol. 12 (2011), 959–965, 10.1038/ni.2091.
    • (2011) Nat. Immunol. , vol.12 , pp. 959-965
    • Zhang, Z.1    Yuan, B.2    Bao, M.3    Lu, N.4    Kim, T.5    Liu, Y.-J.6
  • 23
    • 84870275730 scopus 로고    scopus 로고
    • Extensive evolutionary and functional diversity among mammalian AIM2-like receptors
    • [23] Brunette, R.L., Young, J.M., Whitley, D.G., Brodsky, I.E., Malik, H.S., Stetson, D.B., Extensive evolutionary and functional diversity among mammalian AIM2-like receptors. J. Exp. Med. 209 (2012), 1969–1983, 10.1084/jem.20121960.
    • (2012) J. Exp. Med. , vol.209 , pp. 1969-1983
    • Brunette, R.L.1    Young, J.M.2    Whitley, D.G.3    Brodsky, I.E.4    Malik, H.S.5    Stetson, D.B.6
  • 25
    • 68049092912 scopus 로고    scopus 로고
    • RNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathway
    • [25] Chiu, Y.-H., Macmillan, J.B., Chen, Z.J., RNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathway. Cell. 138 (2009), 576–591, 10.1016/j.cell.2009.06.015.
    • (2009) Cell. , vol.138 , pp. 576-591
    • Chiu, Y.-H.1    Macmillan, J.B.2    Chen, Z.J.3
  • 26
    • 38949093002 scopus 로고    scopus 로고
    • TANK-binding kinase-1 delineates innate and adaptive immune responses to DNA vaccines
    • [26] Ishii, K.J., Kawagoe, T., Koyama, S., Matsui, K., Kumar, H., Kawai, T., et al., TANK-binding kinase-1 delineates innate and adaptive immune responses to DNA vaccines. Nature. 451 (2008), 725–729, 10.1038/nature06537.
    • (2008) Nature. , vol.451 , pp. 725-729
    • Ishii, K.J.1    Kawagoe, T.2    Koyama, S.3    Matsui, K.4    Kumar, H.5    Kawai, T.6
  • 27
    • 84861373256 scopus 로고    scopus 로고
    • Sensing adenovirus infection: activation of interferon regulatory factor 3 in RAW 264.7 cells
    • [27] Stein, S.C., Falck-Pedersen, E., Sensing adenovirus infection: activation of interferon regulatory factor 3 in RAW 264.7 cells. J. Virol. 86 (2012), 4527–4537, 10.1128/JVI.07071-11.
    • (2012) J. Virol. , vol.86 , pp. 4527-4537
    • Stein, S.C.1    Falck-Pedersen, E.2
  • 28
    • 84873711885 scopus 로고    scopus 로고
    • Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway
    • [28] Sun, L., Wu, J., Du, F., Chen, X., Chen, Z.J., Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway. Science. 339 (2013), 786–791, 10.1126/science.1232458.
    • (2013) Science. , vol.339 , pp. 786-791
    • Sun, L.1    Wu, J.2    Du, F.3    Chen, X.4    Chen, Z.J.5
  • 29
    • 84884675857 scopus 로고    scopus 로고
    • Pivotal roles of cGAS-cGAMP signaling in antiviral defense and immune adjuvant effects
    • [29] Li, X.-D., Wu, J., Gao, D., Wang, H., Sun, L., Chen, Z.J., Pivotal roles of cGAS-cGAMP signaling in antiviral defense and immune adjuvant effects. Science. 341 (2013), 1390–1394, 10.1126/science.1244040.
    • (2013) Science. , vol.341 , pp. 1390-1394
    • Li, X.-D.1    Wu, J.2    Gao, D.3    Wang, H.4    Sun, L.5    Chen, Z.J.6
  • 30
    • 84895904323 scopus 로고    scopus 로고
    • Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity
    • [30] Schoggins, J.W., MacDuff, D.A., Imanaka, N., Gainey, M.D., Shrestha, B., Eitson, J.L., et al., Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity. Nature. 505 (2014), 691–695, 10.1038/nature12862.
    • (2014) Nature. , vol.505 , pp. 691-695
    • Schoggins, J.W.1    MacDuff, D.A.2    Imanaka, N.3    Gainey, M.D.4    Shrestha, B.5    Eitson, J.L.6
  • 31
    • 84925841637 scopus 로고    scopus 로고
    • cGAS and Ifi204 cooperate to produce type I IFNs in response to Francisella infection
    • [31] Storek, K.M., Gertsvolf, N.A., Ohlson, M.B., Monack, D.M., cGAS and Ifi204 cooperate to produce type I IFNs in response to Francisella infection. J. Immunol. 194 (2015), 3236–3245, 10.4049/jimmunol.1402764.
    • (2015) J. Immunol. , vol.194 , pp. 3236-3245
    • Storek, K.M.1    Gertsvolf, N.A.2    Ohlson, M.B.3    Monack, D.M.4
  • 32
    • 84930254935 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis differentially activates cGAS- and inflammasome-dependent intracellular immune responses through ESX-1
    • [32] Wassermann, R., Gulen, M.F., Sala, C., Perin, S.G., Lou, Y., Rybniker, J., et al., Mycobacterium tuberculosis differentially activates cGAS- and inflammasome-dependent intracellular immune responses through ESX-1. Cell Host Microbe. 17 (2015), 799–810, 10.1016/j.chom.2015.05.003.
    • (2015) Cell Host Microbe. , vol.17 , pp. 799-810
    • Wassermann, R.1    Gulen, M.F.2    Sala, C.3    Perin, S.G.4    Lou, Y.5    Rybniker, J.6
  • 33
    • 84930268104 scopus 로고    scopus 로고
    • The cytosolic sensor cGAS detects Mycobacterium tuberculosis DNA to induce type I interferons and activate autophagy
    • [33] Watson, R.O., Bell, S.L., MacDuff, D.A., Kimmey, J.M., Diner, E.J., Olivas, J., et al., The cytosolic sensor cGAS detects Mycobacterium tuberculosis DNA to induce type I interferons and activate autophagy. Cell Host Microbe. 17 (2015), 811–819, 10.1016/j.chom.2015.05.004.
    • (2015) Cell Host Microbe. , vol.17 , pp. 811-819
    • Watson, R.O.1    Bell, S.L.2    MacDuff, D.A.3    Kimmey, J.M.4    Diner, E.J.5    Olivas, J.6
  • 34
    • 84930260866 scopus 로고    scopus 로고
    • Cyclic GMP-AMP synthase is an innate immune DNA sensor for Mycobacterium tuberculosis
    • [34] Collins, A.C., Cai, H., Li, T., Franco, L.H., Li, X.-D., Nair, V.R., et al., Cyclic GMP-AMP synthase is an innate immune DNA sensor for Mycobacterium tuberculosis. Cell Host Microbe. 17 (2015), 820–828, 10.1016/j.chom.2015.05.005.
    • (2015) Cell Host Microbe. , vol.17 , pp. 820-828
    • Collins, A.C.1    Cai, H.2    Li, T.3    Franco, L.H.4    Li, X.-D.5    Nair, V.R.6
  • 35
    • 84975229736 scopus 로고    scopus 로고
    • Diminished antiviral innate response to adenovirus vectors in cGAS/STING deficient mice minimally impacts adaptive immunity
    • (JVI.00500–16)
    • [35] Anghelina, D., Lam, E., Falck-Pedersen, E., Diminished antiviral innate response to adenovirus vectors in cGAS/STING deficient mice minimally impacts adaptive immunity. J. Virol., 2016, 10.1128/JVI.00500-16 (JVI.00500–16).
    • (2016) J. Virol.
    • Anghelina, D.1    Lam, E.2    Falck-Pedersen, E.3
  • 36
    • 84861170022 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis activates the DNA-dependent cytosolic surveillance pathway within macrophages
    • [36] Manzanillo, P.S., Shiloh, M.U., Portnoy, D.A., Cox, J.S., Mycobacterium tuberculosis activates the DNA-dependent cytosolic surveillance pathway within macrophages. Cell Host Microbe 11 (2012), 469–480, 10.1016/j.chom.2012.03.007.
    • (2012) Cell Host Microbe , vol.11 , pp. 469-480
    • Manzanillo, P.S.1    Shiloh, M.U.2    Portnoy, D.A.3    Cox, J.S.4
  • 37
    • 38949091132 scopus 로고    scopus 로고
    • Distinct TLR- and NLR-mediated transcriptional responses to an intracellular pathogen
    • e6
    • [37] Leber, J.H., Crimmins, G.T., Raghavan, S., Meyer-Morse, N.P., Cox, J.S., Portnoy, D.A., Distinct TLR- and NLR-mediated transcriptional responses to an intracellular pathogen. PLoS Pathog., 4, 2008, e6, 10.1371/journal.ppat.0040006.
    • (2008) PLoS Pathog. , vol.4
    • Leber, J.H.1    Crimmins, G.T.2    Raghavan, S.3    Meyer-Morse, N.P.4    Cox, J.S.5    Portnoy, D.A.6
  • 38
    • 84907025040 scopus 로고    scopus 로고
    • The DNA sensor, cyclic GMP-AMP synthase, is essential for induction of IFN-β during Chlamydia trachomatis infection
    • [38] Zhang, Y., Yeruva, L., Marinov, A., Prantner, D., Wyrick, P.B., Lupashin, V., et al., The DNA sensor, cyclic GMP-AMP synthase, is essential for induction of IFN-β during Chlamydia trachomatis infection. J. Immunol. 193 (2014), 2394–2404, 10.4049/jimmunol.1302718.
    • (2014) J. Immunol. , vol.193 , pp. 2394-2404
    • Zhang, Y.1    Yeruva, L.2    Marinov, A.3    Prantner, D.4    Wyrick, P.B.5    Lupashin, V.6
  • 39
    • 24344478196 scopus 로고    scopus 로고
    • Type I interferons act directly on CD8 T cells to allow clonal expansion and memory formation in response to viral infection
    • [39] Kolumam, G.A., Thomas, S., Thompson, L.J., Sprent, J., Murali-Krishna, K., Type I interferons act directly on CD8 T cells to allow clonal expansion and memory formation in response to viral infection. J. Exp. Med. 202 (2005), 637–650, 10.1084/jem.20050821.
    • (2005) J. Exp. Med. , vol.202 , pp. 637-650
    • Kolumam, G.A.1    Thomas, S.2    Thompson, L.J.3    Sprent, J.4    Murali-Krishna, K.5
  • 40
    • 32044460431 scopus 로고    scopus 로고
    • Cutting edge: enhancement of antibody responses through direct stimulation of B and T cells by type I IFN
    • [40] Le Bon, A., Thompson, C., Kamphuis, E., Durand, V., Rossmann, C., Kalinke, U., et al., Cutting edge: enhancement of antibody responses through direct stimulation of B and T cells by type I IFN. J. Immunol. 176 (2006), 2074–2078.
    • (2006) J. Immunol. , vol.176 , pp. 2074-2078
    • Le Bon, A.1    Thompson, C.2    Kamphuis, E.3    Durand, V.4    Rossmann, C.5    Kalinke, U.6
  • 41
    • 63949083672 scopus 로고    scopus 로고
    • Interferon-gamma: a historical perspective
    • [41] Billiau, A., Matthys, P., Interferon-gamma: a historical perspective. Cytokine Growth Factor Rev. 20 (2009), 97–113, 10.1016/j.cytogfr.2009.02.004.
    • (2009) Cytokine Growth Factor Rev. , vol.20 , pp. 97-113
    • Billiau, A.1    Matthys, P.2
  • 43
    • 84923000335 scopus 로고    scopus 로고
    • Type I interferons in infectious disease
    • [43] McNab, F., Mayer-Barber, K., Sher, A., Wack, A., O'Garra, A., Type I interferons in infectious disease., 15, 2015, 87–103, 10.1038/nri3787.
    • (2015) , vol.15 , pp. 87-103
    • McNab, F.1    Mayer-Barber, K.2    Sher, A.3    Wack, A.4    O'Garra, A.5
  • 44
    • 34547766513 scopus 로고    scopus 로고
    • ESAT-6 from Mycobacterium tuberculosis dissociates from its putative chaperone CFP-10 under acidic conditions and exhibits membrane-lysing activity
    • [44] de Jonge, M.I., Pehau-Arnaudet, G., Fretz, M.M., Romain, F., Bottai, D., Brodin, P., et al., ESAT-6 from Mycobacterium tuberculosis dissociates from its putative chaperone CFP-10 under acidic conditions and exhibits membrane-lysing activity. J. Bacteriol. 189 (2007), 6028–6034, 10.1128/JB.00469-07.
    • (2007) J. Bacteriol. , vol.189 , pp. 6028-6034
    • de Jonge, M.I.1    Pehau-Arnaudet, G.2    Fretz, M.M.3    Romain, F.4    Bottai, D.5    Brodin, P.6
  • 45
    • 0142059794 scopus 로고    scopus 로고
    • The primary mechanism of attenuation of bacillus Calmette–Guerin is a loss of secreted lytic function required for invasion of lung interstitial tissue
    • [45] Hsu, T., Hingley-Wilson, S.M., Chen, B., Chen, M., Dai, A.Z., Morin, P.M., et al., The primary mechanism of attenuation of bacillus Calmette–Guerin is a loss of secreted lytic function required for invasion of lung interstitial tissue. Proc. Natl. Acad. Sci. U.S.A. 100 (2003), 12,420–12,425, 10.1073/pnas.1635213100.
    • (2003) Proc. Natl. Acad. Sci. U.S.A. , vol.100 , pp. 12420-12425
    • Hsu, T.1    Hingley-Wilson, S.M.2    Chen, B.3    Chen, M.4    Dai, A.Z.5    Morin, P.M.6
  • 46
    • 84886649579 scopus 로고    scopus 로고
    • Effector translocation by the legionella dot/Icm type IV secretion system
    • [46] Qiu, J., Luo, Z.-Q., Effector translocation by the legionella dot/Icm type IV secretion system. Curr. Top. Microbiol. Immunol. 376 (2013), 103–115, 10.1007/82_2013_345.
    • (2013) Curr. Top. Microbiol. Immunol. , vol.376 , pp. 103-115
    • Qiu, J.1    Luo, Z.-Q.2
  • 47
    • 73549090166 scopus 로고    scopus 로고
    • Identification of host cytosolic sensors and bacterial factors regulating the type I interferon response to Legionella pneumophila
    • e1000665
    • [47] Monroe, K.M., McWhirter, S.M., Vance, R.E., Identification of host cytosolic sensors and bacterial factors regulating the type I interferon response to Legionella pneumophila. PLoS Pathog., 5, 2009, e1000665, 10.1371/journal.ppat.1000665.
    • (2009) PLoS Pathog. , vol.5
    • Monroe, K.M.1    McWhirter, S.M.2    Vance, R.E.3
  • 48
    • 84859945146 scopus 로고    scopus 로고
    • Preventing bacterial DNA release and absent in melanoma 2 inflammasome activation by a Legionella effector functioning in membrane trafficking
    • [48] Ge, J., Gong, Y.-N., Xu, Y., Shao, F., Preventing bacterial DNA release and absent in melanoma 2 inflammasome activation by a Legionella effector functioning in membrane trafficking. Proc. Natl. Acad. Sci. U.S.A. 109 (2012), 6193–6198, 10.1073/pnas.1117490109.
    • (2012) Proc. Natl. Acad. Sci. U.S.A. , vol.109 , pp. 6193-6198
    • Ge, J.1    Gong, Y.-N.2    Xu, Y.3    Shao, F.4
  • 49
    • 84857752089 scopus 로고    scopus 로고
    • The protein SdhA maintains the integrity of the Legionella-containing vacuole
    • [49] Creasey, E.A., Isberg, R.R., The protein SdhA maintains the integrity of the Legionella-containing vacuole. Proc. Natl. Acad. Sci. U.S.A. 109 (2012), 3481–3486, 10.1073/pnas.1121286109.
    • (2012) Proc. Natl. Acad. Sci. U.S.A. , vol.109 , pp. 3481-3486
    • Creasey, E.A.1    Isberg, R.R.2
  • 50
    • 0343517154 scopus 로고    scopus 로고
    • Salmonella maintains the integrity of its intracellular vacuole through the action of SifA
    • [50] Beuzón, C.R., Méresse, S., Unsworth, K.E., Ruíz-Albert, J., Garvis, S., Waterman, S.R., et al., Salmonella maintains the integrity of its intracellular vacuole through the action of SifA. EMBO J. 19 (2000), 3235–3249, 10.1093/emboj/19.13.3235.
    • (2000) EMBO J. , vol.19 , pp. 3235-3249
    • Beuzón, C.R.1    Méresse, S.2    Unsworth, K.E.3    Ruíz-Albert, J.4    Garvis, S.5    Waterman, S.R.6
  • 51
    • 84855485784 scopus 로고    scopus 로고
    • Host innate recognition of an intestinal bacterial pathogen induces TRIF-dependent protective immunity
    • [51] Sotolongo, J., España, C., Echeverry, A., Siefker, D., Altman, N., Zaias, J., et al., Host innate recognition of an intestinal bacterial pathogen induces TRIF-dependent protective immunity. J. Exp. Med. 208 (2011), 2705–2716, 10.1084/jem.20110547.
    • (2011) J. Exp. Med. , vol.208 , pp. 2705-2716
    • Sotolongo, J.1    España, C.2    Echeverry, A.3    Siefker, D.4    Altman, N.5    Zaias, J.6
  • 52
    • 67651125824 scopus 로고    scopus 로고
    • A host type I interferon response is induced by cytosolic sensing of the bacterial second messenger cyclic-di-GMP
    • [52] McWhirter, S.M., Barbalat, R., Monroe, K.M., Fontana, M.F., Hyodo, M., Joncker, N.T., et al., A host type I interferon response is induced by cytosolic sensing of the bacterial second messenger cyclic-di-GMP. J. Exp. Med. 206 (2009), 1899–1911, 10.1084/jem.20082874.
    • (2009) J. Exp. Med. , vol.206 , pp. 1899-1911
    • McWhirter, S.M.1    Barbalat, R.2    Monroe, K.M.3    Fontana, M.F.4    Hyodo, M.5    Joncker, N.T.6
  • 53
    • 77954070545 scopus 로고    scopus 로고
    • c-di-AMP secreted by intracellular Listeria monocytogenes activates a host type I interferon response
    • [53] Woodward, J.J., Iavarone, A.T., Portnoy, D.A., c-di-AMP secreted by intracellular Listeria monocytogenes activates a host type I interferon response. Science 328 (2010), 1703–1705, 10.1126/science.1189801.
    • (2010) Science , vol.328 , pp. 1703-1705
    • Woodward, J.J.1    Iavarone, A.T.2    Portnoy, D.A.3
  • 54
    • 84863722786 scopus 로고    scopus 로고
    • The structural basis for the sensing and binding of cyclic di-GMP by STING
    • [54] Huang, Y.-H., Liu, X.-Y., Du, X.-X., Jiang, Z.-F., Su, X.-D., The structural basis for the sensing and binding of cyclic di-GMP by STING. Nat. Struct. Mol. Biol. 19 (2012), 728–730, 10.1038/nsmb.2333.
    • (2012) Nat. Struct. Mol. Biol. , vol.19 , pp. 728-730
    • Huang, Y.-H.1    Liu, X.-Y.2    Du, X.-X.3    Jiang, Z.-F.4    Su, X.-D.5
  • 55
    • 84878616469 scopus 로고    scopus 로고
    • STING-dependent recognition of cyclic di-AMP mediates type I interferon responses during Chlamydia trachomatis infection
    • e00018–13
    • [55] Barker, J.R., Koestler, B.J., Carpenter, V.K., Burdette, D.L., Waters, C.M., Vance, R.E., et al., STING-dependent recognition of cyclic di-AMP mediates type I interferon responses during Chlamydia trachomatis infection. MBio., 4, 2013, e00018–13, 10.1128/mBio.00018-13.
    • (2013) MBio. , vol.4
    • Barker, J.R.1    Koestler, B.J.2    Carpenter, V.K.3    Burdette, D.L.4    Waters, C.M.5    Vance, R.E.6
  • 56
    • 84940000532 scopus 로고    scopus 로고
    • A bacterial cyclic dinucleotide activates the cytosolic surveillance pathway and mediates innate resistance to tuberculosis
    • [56] Dey, B., Dey, R.J., Cheung, L.S., Pokkali, S., Guo, H., Lee, J.-H., et al., A bacterial cyclic dinucleotide activates the cytosolic surveillance pathway and mediates innate resistance to tuberculosis. Nat. Med. 21 (2015), 401–406, 10.1038/nm.3813.
    • (2015) Nat. Med. , vol.21 , pp. 401-406
    • Dey, B.1    Dey, R.J.2    Cheung, L.S.3    Pokkali, S.4    Guo, H.5    Lee, J.-H.6
  • 57
    • 84905375825 scopus 로고    scopus 로고
    • Listeria monocytogenes induces IFNβ expression through an IFI16-, cGAS-, and STING-dependent pathway
    • [57] Hansen, K., Prabakaran, T., Laustsen, A., Jørgensen, S.E., Rahbæk, S.H., Jensen, S.B., et al., Listeria monocytogenes induces IFNβ expression through an IFI16-, cGAS-, and STING-dependent pathway. EMBO J. 33 (2014), 1654–1666, 10.15252/embj.201488029.
    • (2014) EMBO J. , vol.33 , pp. 1654-1666
    • Hansen, K.1    Prabakaran, T.2    Laustsen, A.3    Jørgensen, S.E.4    Rahbæk, S.H.5    Jensen, S.B.6
  • 58
    • 84888637695 scopus 로고    scopus 로고
    • Cell intrinsic immunity spreads to bystander cells via the intercellular transfer of cGAMP
    • [58] Ablasser, A., Schmid-Burgk, J.L., Hemmerling, I., Horvath, G.L., Schmidt, T., Latz, E., et al., Cell intrinsic immunity spreads to bystander cells via the intercellular transfer of cGAMP. Nature. 503 (2013), 530–534, 10.1038/nature12640.
    • (2013) Nature. , vol.503 , pp. 530-534
    • Ablasser, A.1    Schmid-Burgk, J.L.2    Hemmerling, I.3    Horvath, G.L.4    Schmidt, T.5    Latz, E.6
  • 59
    • 84863993689 scopus 로고    scopus 로고
    • ESX-1-mediated translocation to the cytosol controls virulence of mycobacteria
    • [59] Houben, D., Demangel, C., van Ingen, J., Perez, J., Baldeón, L., Abdallah, A.M., et al., ESX-1-mediated translocation to the cytosol controls virulence of mycobacteria. Cell. Microbiol. 14 (2012), 1287–1298, 10.1111/j.1462-5822.2012.01799.x.
    • (2012) Cell. Microbiol. , vol.14 , pp. 1287-1298
    • Houben, D.1    Demangel, C.2    van Ingen, J.3    Perez, J.4    Baldeón, L.5    Abdallah, A.M.6
  • 60
    • 0028864798 scopus 로고
    • A null mutation in the gene encoding a type I interferon receptor component eliminates antiproliferative and antiviral responses to interferons alpha and beta and alters macrophage responses
    • [60] Hwang, S.Y., Hertzog, P.J., Holland, K.A., Sumarsono, S.H., Tymms, M.J., Hamilton, J.A., et al., A null mutation in the gene encoding a type I interferon receptor component eliminates antiproliferative and antiviral responses to interferons alpha and beta and alters macrophage responses. Proc. Natl. Acad. Sci. U.S.A. 92 (1995), 11,284–11,288.
    • (1995) Proc. Natl. Acad. Sci. U.S.A. , vol.92 , pp. 11284-11288
    • Hwang, S.Y.1    Hertzog, P.J.2    Holland, K.A.3    Sumarsono, S.H.4    Tymms, M.J.5    Hamilton, J.A.6
  • 61
    • 0028070714 scopus 로고
    • Functional role of type I and type II interferons in antiviral defense
    • [61] Müller, U., Steinhoff, U., Reis, L.F., Hemmi, S., Pavlovic, J., Zinkernagel, R.M., et al., Functional role of type I and type II interferons in antiviral defense. Science. 264 (1994), 1918–1921.
    • (1994) Science. , vol.264 , pp. 1918-1921
    • Müller, U.1    Steinhoff, U.2    Reis, L.F.3    Hemmi, S.4    Pavlovic, J.5    Zinkernagel, R.M.6
  • 62
    • 33847359299 scopus 로고    scopus 로고
    • The type I IFN response to infection with Mycobacterium tuberculosis requires ESX-1-mediated secretion and contributes to pathogenesis
    • [62] Stanley, S.A., Johndrow, J.E., Manzanillo, P., Cox, J.S., The type I IFN response to infection with Mycobacterium tuberculosis requires ESX-1-mediated secretion and contributes to pathogenesis. J. Immunol. 178 (2007), 3143–3152.
    • (2007) J. Immunol. , vol.178 , pp. 3143-3152
    • Stanley, S.A.1    Johndrow, J.E.2    Manzanillo, P.3    Cox, J.S.4
  • 63
    • 84903750131 scopus 로고    scopus 로고
    • Host-directed therapy of tuberculosis based on interleukin-1 and type I interferon crosstalk
    • [63] Mayer-Barber, K.D., Andrade, B.B., Oland, S.D., Amaral, E.P., Barber, D.L., Gonzales, J., et al., Host-directed therapy of tuberculosis based on interleukin-1 and type I interferon crosstalk. Nature. 511 (2014), 99–103, 10.1038/nature13489.
    • (2014) Nature. , vol.511 , pp. 99-103
    • Mayer-Barber, K.D.1    Andrade, B.B.2    Oland, S.D.3    Amaral, E.P.4    Barber, D.L.5    Gonzales, J.6
  • 64
    • 34250794992 scopus 로고    scopus 로고
    • The hypervirulent Mycobacterium tuberculosis strain HN878 induces a potent TH1 response followed by rapid down-regulation
    • [64] Ordway, D., Henao-Tamayo, M., Harton, M., Palanisamy, G., Troudt, J., Shanley, C., et al., The hypervirulent Mycobacterium tuberculosis strain HN878 induces a potent TH1 response followed by rapid down-regulation. J. Immunol. 179 (2007), 522–531.
    • (2007) J. Immunol. , vol.179 , pp. 522-531
    • Ordway, D.1    Henao-Tamayo, M.2    Harton, M.3    Palanisamy, G.4    Troudt, J.5    Shanley, C.6
  • 65
    • 0035826721 scopus 로고    scopus 로고
    • Virulence of a Mycobacterium tuberculosis clinical isolate in mice is determined by failure to induce Th1 type immunity and is associated with induction of IFN-alpha /beta
    • [65] Manca, C., Tsenova, L., Bergtold, A., Freeman, S., Tovey, M., Musser, J.M., et al., Virulence of a Mycobacterium tuberculosis clinical isolate in mice is determined by failure to induce Th1 type immunity and is associated with induction of IFN-alpha /beta. Proc. Natl. Acad. Sci. U.S.A. 98 (2001), 5752–5757, 10.1073/pnas.091096998.
    • (2001) Proc. Natl. Acad. Sci. U.S.A. , vol.98 , pp. 5752-5757
    • Manca, C.1    Tsenova, L.2    Bergtold, A.3    Freeman, S.4    Tovey, M.5    Musser, J.M.6
  • 66
    • 4344601300 scopus 로고    scopus 로고
    • Mice lacking the type I interferon receptor are resistant to Listeria monocytogenes
    • [66] Auerbuch, V., Brockstedt, D.G., Meyer-Morse, N., O'Riordan, M., Portnoy, D.A., Mice lacking the type I interferon receptor are resistant to Listeria monocytogenes. J. Exp. Med. 200 (2004), 527–533, 10.1084/jem.20040976.
    • (2004) J. Exp. Med. , vol.200 , pp. 527-533
    • Auerbuch, V.1    Brockstedt, D.G.2    Meyer-Morse, N.3    O'Riordan, M.4    Portnoy, D.A.5
  • 67
    • 4344627833 scopus 로고    scopus 로고
    • Type I interferon production enhances susceptibility to Listeria monocytogenes infection
    • [67] O'Connell, R.M., Saha, S.K., Vaidya, S.A., Bruhn, K.W., Miranda, G.A., Zarnegar, B., et al., Type I interferon production enhances susceptibility to Listeria monocytogenes infection. J. Exp. Med. 200 (2004), 437–445, 10.1084/jem.20040712.
    • (2004) J. Exp. Med. , vol.200 , pp. 437-445
    • O'Connell, R.M.1    Saha, S.K.2    Vaidya, S.A.3    Bruhn, K.W.4    Miranda, G.A.5    Zarnegar, B.6
  • 68
    • 29444432905 scopus 로고    scopus 로고
    • Hypervirulent M. Tuberculosis W/Beijing strains upregulate type I IFNs and increase expression of negative regulators of the Jak–Stat pathway
    • [68] Manca, C., Tsenova, L., Freeman, S., Barczak, A.K., Tovey, M., Murray, P.J., et al., Hypervirulent M. Tuberculosis W/Beijing strains upregulate type I IFNs and increase expression of negative regulators of the Jak–Stat pathway. J. Interf. Cytokine Res. 25 (2005), 694–701, 10.1089/jir.2005.25.694.
    • (2005) J. Interf. Cytokine Res. , vol.25 , pp. 694-701
    • Manca, C.1    Tsenova, L.2    Freeman, S.3    Barczak, A.K.4    Tovey, M.5    Murray, P.J.6
  • 69
    • 77149132187 scopus 로고    scopus 로고
    • Induction of IFN-alphabeta enables Listeria monocytogenes to suppress macrophage activation by IFN-gamma
    • [69] Rayamajhi, M., Humann, J., Penheiter, K., Andreasen, K., Lenz, L.L., Induction of IFN-alphabeta enables Listeria monocytogenes to suppress macrophage activation by IFN-gamma. J. Exp. Med. 207 (2010), 327–337, 10.1084/jem.20091746.
    • (2010) J. Exp. Med. , vol.207 , pp. 327-337
    • Rayamajhi, M.1    Humann, J.2    Penheiter, K.3    Andreasen, K.4    Lenz, L.L.5
  • 70
    • 34248395113 scopus 로고    scopus 로고
    • Modulation of gamma interferon receptor 1 by Mycobacterium tuberculosis: a potential immune response evasive mechanism
    • [70] Singhal, A., Jaiswal, A., Arora, V.K., Prasad, H.K., Modulation of gamma interferon receptor 1 by Mycobacterium tuberculosis: a potential immune response evasive mechanism. Infect. Immun. 75 (2007), 2500–2510, 10.1128/IAI.01743-06.
    • (2007) Infect. Immun. , vol.75 , pp. 2500-2510
    • Singhal, A.1    Jaiswal, A.2    Arora, V.K.3    Prasad, H.K.4
  • 71
    • 58049217443 scopus 로고    scopus 로고
    • Francisella inhibits STAT1-mediated signaling in macrophages and prevents activation of antigen-specific T cells
    • [71] Roth, K.M., Gunn, J.S., Lafuse, W., Satoskar, A.R., Francisella inhibits STAT1-mediated signaling in macrophages and prevents activation of antigen-specific T cells. Int. Immunol. 21 (2009), 19–28, 10.1093/intimm/dxn119.
    • (2009) Int. Immunol. , vol.21 , pp. 19-28
    • Roth, K.M.1    Gunn, J.S.2    Lafuse, W.3    Satoskar, A.R.4
  • 72
    • 84866686896 scopus 로고    scopus 로고
    • Genome-wide expression profiling identifies type 1 interferon response pathways in active tuberculosis
    • e45839
    • [72] Ottenhoff, T.H.M., Dass, R.H., Yang, N., Zhang, M.M., Wong, H.E.E., Sahiratmadja, E., et al., Genome-wide expression profiling identifies type 1 interferon response pathways in active tuberculosis. PLoS ONE., 7, 2012, e45839, 10.1371/journal.pone.0045839.
    • (2012) PLoS ONE. , vol.7
    • Ottenhoff, T.H.M.1    Dass, R.H.2    Yang, N.3    Zhang, M.M.4    Wong, H.E.E.5    Sahiratmadja, E.6
  • 73
    • 84951096740 scopus 로고    scopus 로고
    • A single bacterial immune evasion strategy dismantles both MyD88 and TRIF signaling pathways downstream of TLR4
    • [73] Rosadini, C.V., Zanoni, I., Odendall, C., Green, E.R., Paczosa, M.K., Philip, N.H., et al., A single bacterial immune evasion strategy dismantles both MyD88 and TRIF signaling pathways downstream of TLR4. Cell Host Microbe. 18 (2015), 682–693, 10.1016/j.chom.2015.11.006.
    • (2015) Cell Host Microbe. , vol.18 , pp. 682-693
    • Rosadini, C.V.1    Zanoni, I.2    Odendall, C.3    Green, E.R.4    Paczosa, M.K.5    Philip, N.H.6
  • 74
    • 84960156468 scopus 로고    scopus 로고
    • Salmonella suppresses the TRIF-dependent type I interferon response in macrophages
    • e02051–15
    • [74] Owen, K.A., Anderson, C.J., Casanova, J.E., Salmonella suppresses the TRIF-dependent type I interferon response in macrophages. MBio., 7, 2015, e02051–15, 10.1128/mBio.02051-15.
    • (2015) MBio. , vol.7
    • Owen, K.A.1    Anderson, C.J.2    Casanova, J.E.3
  • 75
    • 84926489965 scopus 로고    scopus 로고
    • Induction of interferon-stimulated genes by IRF3 promotes replication of Toxoplasma gondii
    • e1004779
    • [75] Majumdar, T., Chattopadhyay, S., Ozhegov, E., Dhar, J., Goswami, R., Sen, G.C., et al., Induction of interferon-stimulated genes by IRF3 promotes replication of Toxoplasma gondii. PLoS Pathog., 11, 2015, e1004779, 10.1371/journal.ppat.1004779.
    • (2015) PLoS Pathog. , vol.11
    • Majumdar, T.1    Chattopadhyay, S.2    Ozhegov, E.3    Dhar, J.4    Goswami, R.5    Sen, G.C.6
  • 76
    • 84879195120 scopus 로고    scopus 로고
    • Innate and adaptive effects of inflammasomes on T cell responses
    • [76] Dostert, C., Ludigs, K., Guarda, G., Innate and adaptive effects of inflammasomes on T cell responses. Curr. Opin. Immunol. 25 (2013), 359–365, 10.1016/j.coi.2013.02.008.
    • (2013) Curr. Opin. Immunol. , vol.25 , pp. 359-365
    • Dostert, C.1    Ludigs, K.2    Guarda, G.3
  • 77
    • 34548027736 scopus 로고    scopus 로고
    • Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration
    • [77] Pétrilli, V., Papin, S., Dostert, C., Mayor, A., Martinon, F., Tschopp, J., Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration. Cell Death Differ. 14 (2007), 1583–1589, 10.1038/sj.cdd.4402195.
    • (2007) Cell Death Differ. , vol.14 , pp. 1583-1589
    • Pétrilli, V.1    Papin, S.2    Dostert, C.3    Mayor, A.4    Martinon, F.5    Tschopp, J.6
  • 78
    • 31744441475 scopus 로고    scopus 로고
    • Nalp1b controls mouse macrophage susceptibility to anthrax lethal toxin
    • [78] Boyden, E.D., Dietrich, W.F., Nalp1b controls mouse macrophage susceptibility to anthrax lethal toxin. Nat. Genet. 38 (2006), 240–244, 10.1038/ng1724.
    • (2006) Nat. Genet. , vol.38 , pp. 240-244
    • Boyden, E.D.1    Dietrich, W.F.2
  • 79
    • 33744464740 scopus 로고    scopus 로고
    • Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta in salmonella-infected macrophages
    • [79] Franchi, L., Amer, A., Body-Malapel, M., Kanneganti, T.-D., Özören, N., Jagirdar, R., et al., Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta in salmonella-infected macrophages. Nat. Immunol. 7 (2006), 576–582, 10.1038/ni1346.
    • (2006) Nat. Immunol. , vol.7 , pp. 576-582
    • Franchi, L.1    Amer, A.2    Body-Malapel, M.3    Kanneganti, T.-D.4    Özören, N.5    Jagirdar, R.6
  • 80
    • 45549092412 scopus 로고    scopus 로고
    • NAIP and Ipaf control Legionella pneumophila replication in human cells
    • [80] Vinzing, M., Eitel, J., Lippmann, J., Hocke, A.C., Zahlten, J., Slevogt, H., et al., NAIP and Ipaf control Legionella pneumophila replication in human cells. J. Immunol. 180 (2008), 6808–6815.
    • (2008) J. Immunol. , vol.180 , pp. 6808-6815
    • Vinzing, M.1    Eitel, J.2    Lippmann, J.3    Hocke, A.C.4    Zahlten, J.5    Slevogt, H.6
  • 81
    • 84911192502 scopus 로고    scopus 로고
    • RNA viruses promote activation of the NLRP3 inflammasome through a RIP1-RIP3-DRP1 signaling pathway
    • [81] Wang, X., Jiang, W., Yan, Y., Gong, T., Han, J., Tian, Z., et al., RNA viruses promote activation of the NLRP3 inflammasome through a RIP1-RIP3-DRP1 signaling pathway. Nat. Immunol. 15 (2014), 1126–1133, 10.1038/ni.3015.
    • (2014) Nat. Immunol. , vol.15 , pp. 1126-1133
    • Wang, X.1    Jiang, W.2    Yan, Y.3    Gong, T.4    Han, J.5    Tian, Z.6
  • 82
    • 84927050914 scopus 로고    scopus 로고
    • RNase L activates the NLRP3 inflammasome during viral infections
    • [82] Chakrabarti, A., Banerjee, S., Franchi, L., Loo, Y.-M., Gale, M., Nuñez, G., et al., RNase L activates the NLRP3 inflammasome during viral infections. Cell Host Microbe. 17 (2015), 466–477, 10.1016/j.chom.2015.02.010.
    • (2015) Cell Host Microbe. , vol.17 , pp. 466-477
    • Chakrabarti, A.1    Banerjee, S.2    Franchi, L.3    Loo, Y.-M.4    Gale, M.5    Nuñez, G.6
  • 83
    • 64049111768 scopus 로고    scopus 로고
    • The NLRP3 inflammasome mediates in vivo innate immunity to influenza A virus through recognition of viral RNA
    • [83] Allen, I.C., Scull, M.A., Moore, C.B., Holl, E.K., McElvania-TeKippe, E., Taxman, D.J., et al., The NLRP3 inflammasome mediates in vivo innate immunity to influenza A virus through recognition of viral RNA. Immunity. 30 (2009), 556–565, 10.1016/j.immuni.2009.02.005.
    • (2009) Immunity. , vol.30 , pp. 556-565
    • Allen, I.C.1    Scull, M.A.2    Moore, C.B.3    Holl, E.K.4    McElvania-TeKippe, E.5    Taxman, D.J.6
  • 84
    • 32944468985 scopus 로고    scopus 로고
    • Gout-associated uric acid crystals activate the NALP3 inflammasome
    • [84] Martinon, F., Petrilli, V., Mayor, A., Tardivel, A., Tschopp, J., Gout-associated uric acid crystals activate the NALP3 inflammasome. Nature. 440 (2006), 237–241, 10.1038/nature04516.
    • (2006) Nature. , vol.440 , pp. 237-241
    • Martinon, F.1    Petrilli, V.2    Mayor, A.3    Tardivel, A.4    Tschopp, J.5
  • 85
    • 63649145255 scopus 로고    scopus 로고
    • AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
    • [85] Fernandes-Alnemri, T., Yu, J.-W., Datta, P., Wu, J., Alnemri, E.S., AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA. Nature. 458 (2009), 509–513, 10.1038/nature07710.
    • (2009) Nature. , vol.458 , pp. 509-513
    • Fernandes-Alnemri, T.1    Yu, J.-W.2    Datta, P.3    Wu, J.4    Alnemri, E.S.5
  • 86
    • 77951269392 scopus 로고    scopus 로고
    • The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses
    • [86] Rathinam, V.A.K., Jiang, Z., Waggoner, S.N., Sharma, S., Cole, L.E., Waggoner, L., et al., The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses. Nat. Immunol. 11 (2010), 395–402, 10.1038/ni.1864.
    • (2010) Nat. Immunol. , vol.11 , pp. 395-402
    • Rathinam, V.A.K.1    Jiang, Z.2    Waggoner, S.N.3    Sharma, S.4    Cole, L.E.5    Waggoner, L.6
  • 87
    • 84920377134 scopus 로고    scopus 로고
    • Interferon-induced guanylate-binding proteins promote cytosolic lipopolysaccharide detection by caspase-11
    • [87] Meunier, E., Broz, P., Interferon-induced guanylate-binding proteins promote cytosolic lipopolysaccharide detection by caspase-11. DNA Cell Biol. 34 (2015), 1–5, 10.1089/dna.2014.2701.
    • (2015) DNA Cell Biol. , vol.34 , pp. 1-5
    • Meunier, E.1    Broz, P.2
  • 88
    • 84928545520 scopus 로고    scopus 로고
    • The transcription factor IRF1 and guanylate-binding proteins target activation of the AIM2 inflammasome by Francisella infection
    • [88] Man, S.M., Karki, R., Malireddi, R.K.S., Neale, G., Vogel, P., Yamamoto, M., et al., The transcription factor IRF1 and guanylate-binding proteins target activation of the AIM2 inflammasome by Francisella infection. Nat. Immunol. 16 (2015), 467–475, 10.1038/ni.3118.
    • (2015) Nat. Immunol. , vol.16 , pp. 467-475
    • Man, S.M.1    Karki, R.2    Malireddi, R.K.S.3    Neale, G.4    Vogel, P.5    Yamamoto, M.6
  • 89
    • 84949652170 scopus 로고    scopus 로고
    • Guanylate binding proteins enable rapid activation of canonical and noncanonical inflammasomes in chlamydia-infected macrophages
    • [89] Finethy, R., Jorgensen, I., Haldar, A.K., de Zoete, M.R., Strowig, T., Flavell, R.A., et al., Guanylate binding proteins enable rapid activation of canonical and noncanonical inflammasomes in chlamydia-infected macrophages. Infect. Immun. 83 (2015), 4740–4749, 10.1128/IAI.00856-15.
    • (2015) Infect. Immun. , vol.83 , pp. 4740-4749
    • Finethy, R.1    Jorgensen, I.2    Haldar, A.K.3    de Zoete, M.R.4    Strowig, T.5    Flavell, R.A.6
  • 90
    • 77955294800 scopus 로고    scopus 로고
    • Listeria monocytogenes triggers AIM2-mediated pyroptosis upon infrequent bacteriolysis in the macrophage cytosol
    • [90] Sauer, J.-D., Witte, C.E., Zemansky, J., Hanson, B., Lauer, P., Portnoy, D.A., Listeria monocytogenes triggers AIM2-mediated pyroptosis upon infrequent bacteriolysis in the macrophage cytosol. Cell Host Microbe. 7 (2010), 412–419, 10.1016/j.chom.2010.04.004.
    • (2010) Cell Host Microbe. , vol.7 , pp. 412-419
    • Sauer, J.-D.1    Witte, C.E.2    Zemansky, J.3    Hanson, B.4    Lauer, P.5    Portnoy, D.A.6
  • 91
    • 84867136602 scopus 로고    scopus 로고
    • Critical role of AIM2 in Mycobacterium tuberculosis infection
    • [91] Saiga, H., Kitada, S., Shimada, Y., Kamiyama, N., Okuyama, M., Makino, M., et al., Critical role of AIM2 in Mycobacterium tuberculosis infection. Int. Immunol. 24 (2012), 637–644, 10.1093/intimm/dxs062.
    • (2012) Int. Immunol. , vol.24 , pp. 637-644
    • Saiga, H.1    Kitada, S.2    Shimada, Y.3    Kamiyama, N.4    Okuyama, M.5    Makino, M.6
  • 92
    • 84885093565 scopus 로고    scopus 로고
    • Cutting edge: Mycobacterium tuberculosis but not nonvirulent mycobacteria inhibits IFN-β and AIM2 inflammasome-dependent IL-1β production via its ESX-1 secretion system
    • [92] Shah, S., Bohsali, A., Ahlbrand, S.E., Srinivasan, L., Rathinam, V.A.K., Vogel, S.N., et al., Cutting edge: Mycobacterium tuberculosis but not nonvirulent mycobacteria inhibits IFN-β and AIM2 inflammasome-dependent IL-1β production via its ESX-1 secretion system. J. Immunol. 191 (2013), 3514–3518, 10.4049/jimmunol.1301331.
    • (2013) J. Immunol. , vol.191 , pp. 3514-3518
    • Shah, S.1    Bohsali, A.2    Ahlbrand, S.E.3    Srinivasan, L.4    Rathinam, V.A.K.5    Vogel, S.N.6
  • 93
    • 84857195479 scopus 로고    scopus 로고
    • Activation of autophagy by inflammatory signals limits IL-1β production by targeting ubiquitinated inflammasomes for destruction
    • [93] Shi, C.-S., Shenderov, K., Huang, N.-N., Kabat, J., Abu-Asab, M., Fitzgerald, K.A., et al., Activation of autophagy by inflammatory signals limits IL-1β production by targeting ubiquitinated inflammasomes for destruction. Nat. Immunol. 13 (2012), 255–263, 10.1038/ni.2215.
    • (2012) Nat. Immunol. , vol.13 , pp. 255-263
    • Shi, C.-S.1    Shenderov, K.2    Huang, N.-N.3    Kabat, J.4    Abu-Asab, M.5    Fitzgerald, K.A.6
  • 94
    • 77953116282 scopus 로고    scopus 로고
    • Absent in melanoma 2 is required for innate immune recognition of Francisella tularensis
    • [94] Jones, J.W., Kayagaki, N., Broz, P., Henry, T., Newton, K., O'Rourke, K., et al., Absent in melanoma 2 is required for innate immune recognition of Francisella tularensis. Proc. Natl. Acad. Sci. U.S.A. 107 (2010), 9771–9776, 10.1073/pnas.1003738107.
    • (2010) Proc. Natl. Acad. Sci. U.S.A. , vol.107 , pp. 9771-9776
    • Jones, J.W.1    Kayagaki, N.2    Broz, P.3    Henry, T.4    Newton, K.5    O'Rourke, K.6
  • 95
    • 34447643958 scopus 로고    scopus 로고
    • Toll-like receptor 4 is a sensor for autophagy associated with innate immunity
    • [95] Xu, Y., Jagannath, C., Liu, X.-D., Sharafkhaneh, A., Kolodziejska, K.E., Eissa, N.T., Toll-like receptor 4 is a sensor for autophagy associated with innate immunity. Immunity. 27 (2007), 135–144, 10.1016/j.immuni.2007.05.022.
    • (2007) Immunity. , vol.27 , pp. 135-144
    • Xu, Y.1    Jagannath, C.2    Liu, X.-D.3    Sharafkhaneh, A.4    Kolodziejska, K.E.5    Eissa, N.T.6
  • 96
    • 33947134377 scopus 로고    scopus 로고
    • Autophagy-dependent viral recognition by plasmacytoid dendritic cells
    • [96] Lee, H.K., Lund, J.M., Ramanathan, B., Mizushima, N., Iwasaki, A., Autophagy-dependent viral recognition by plasmacytoid dendritic cells. Science. 315 (2007), 1398–1401, 10.1126/science.1136880.
    • (2007) Science. , vol.315 , pp. 1398-1401
    • Lee, H.K.1    Lund, J.M.2    Ramanathan, B.3    Mizushima, N.4    Iwasaki, A.5
  • 97
    • 37549043217 scopus 로고    scopus 로고
    • Toll-like receptor signalling in macrophages links the autophagy pathway to phagocytosis
    • [97] Sanjuan, M.A., Dillon, C.P., Tait, S.W.G., Moshiach, S., Dorsey, F., Connell, S., et al., Toll-like receptor signalling in macrophages links the autophagy pathway to phagocytosis. Nature. 450 (2007), 1253–1257, 10.1038/nature06421.
    • (2007) Nature. , vol.450 , pp. 1253-1257
    • Sanjuan, M.A.1    Dillon, C.P.2    Tait, S.W.G.3    Moshiach, S.4    Dorsey, F.5    Connell, S.6
  • 98
    • 73849151394 scopus 로고    scopus 로고
    • NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation
    • [98] Cooney, R., Baker, J., Brain, O., Danis, B., Pichulik, T., Allan, P., et al., NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation. Nat. Med. 16 (2010), 90–97, 10.1038/nm.2069.
    • (2010) Nat. Med. , vol.16 , pp. 90-97
    • Cooney, R.1    Baker, J.2    Brain, O.3    Danis, B.4    Pichulik, T.5    Allan, P.6
  • 99
    • 84898624312 scopus 로고    scopus 로고
    • Self and nonself: how autophagy targets mitochondria and bacteria
    • [99] Randow, F., Youle, R.J., Self and nonself: how autophagy targets mitochondria and bacteria. Cell Host Microbe. 15 (2014), 403–411, 10.1016/j.chom.2014.03.012.
    • (2014) Cell Host Microbe. , vol.15 , pp. 403-411
    • Randow, F.1    Youle, R.J.2
  • 100
    • 84893912159 scopus 로고    scopus 로고
    • Crosstalk between the cGAS DNA sensor and Beclin-1 autophagy protein shapes innate antimicrobial immune responses
    • [100] Liang, Q., Seo, G.J., Choi, Y.J., Kwak, M.-J., Ge, J., Rodgers, M.A., et al., Crosstalk between the cGAS DNA sensor and Beclin-1 autophagy protein shapes innate antimicrobial immune responses. Cell Host Microbe. 15 (2014), 228–238, 10.1016/j.chom.2014.01.009.
    • (2014) Cell Host Microbe. , vol.15 , pp. 228-238
    • Liang, Q.1    Seo, G.J.2    Choi, Y.J.3    Kwak, M.-J.4    Ge, J.5    Rodgers, M.A.6
  • 101
    • 84879589271 scopus 로고    scopus 로고
    • Cyclic di-AMP is critical for Listeria monocytogenes growth, cell wall homeostasis, and establishment of infection
    • e00282–13
    • [101] Witte, C.E., Whiteley, A.T., Burke, T.P., Sauer, J.-D., Portnoy, D.A., Woodward, J.J., Cyclic di-AMP is critical for Listeria monocytogenes growth, cell wall homeostasis, and establishment of infection. MBio., 4, 2013, e00282–13, 10.1128/mBio.00282-13.
    • (2013) MBio. , vol.4
    • Witte, C.E.1    Whiteley, A.T.2    Burke, T.P.3    Sauer, J.-D.4    Portnoy, D.A.5    Woodward, J.J.6
  • 102
    • 77953496542 scopus 로고    scopus 로고
    • NDP52, a novel autophagy receptor for ubiquitin-decorated cytosolic bacteria
    • [102] von Muhlinen, N., Thurston, T., Ryzhakov, G., Bloor, S., Randow, F., NDP52, a novel autophagy receptor for ubiquitin-decorated cytosolic bacteria. Autophagy. 6 (2010), 288–289.
    • (2010) Autophagy. , vol.6 , pp. 288-289
    • von Muhlinen, N.1    Thurston, T.2    Ryzhakov, G.3    Bloor, S.4    Randow, F.5
  • 103
    • 70350450808 scopus 로고    scopus 로고
    • The TBK1 adaptor and autophagy receptor NDP52 restricts the proliferation of ubiquitin-coated bacteria
    • [103] Thurston, T.L.M., Ryzhakov, G., Bloor, S., von Muhlinen, N., Randow, F., The TBK1 adaptor and autophagy receptor NDP52 restricts the proliferation of ubiquitin-coated bacteria. Nat. Immunol. 10 (2009), 1215–1221, 10.1038/ni.1800.
    • (2009) Nat. Immunol. , vol.10 , pp. 1215-1221
    • Thurston, T.L.M.1    Ryzhakov, G.2    Bloor, S.3    von Muhlinen, N.4    Randow, F.5
  • 104
    • 84857071710 scopus 로고    scopus 로고
    • Galectin 8 targets damaged vesicles for autophagy to defend cells against bacterial invasion
    • [104] Thurston, T.L.M., Wandel, M.P., von Muhlinen, N., Foeglein, A., Randow, F., Galectin 8 targets damaged vesicles for autophagy to defend cells against bacterial invasion. Nature. 482 (2012), 414–418, 10.1038/nature10744.
    • (2012) Nature. , vol.482 , pp. 414-418
    • Thurston, T.L.M.1    Wandel, M.P.2    von Muhlinen, N.3    Foeglein, A.4    Randow, F.5
  • 105
    • 84879513881 scopus 로고    scopus 로고
    • Streptolysin O and its co-toxin NAD-glycohydrolase protect group A Streptococcus from Xenophagic killing
    • e1003394
    • [105] O'Seaghdha, M., Wessels, M.R., Streptolysin O and its co-toxin NAD-glycohydrolase protect group A Streptococcus from Xenophagic killing. PLoS Pathog., 9, 2013, e1003394, 10.1371/journal.ppat.1003394.
    • (2013) PLoS Pathog. , vol.9
    • O'Seaghdha, M.1    Wessels, M.R.2
  • 106
    • 0027360333 scopus 로고
    • An essential role for interferon gamma in resistance to Mycobacterium tuberculosis infection
    • [106] Flynn, J.L., Chan, J., Triebold, K.J., Dalton, D.K., Stewart, T.A., Bloom, B.R., An essential role for interferon gamma in resistance to Mycobacterium tuberculosis infection. J. Exp. Med. 178 (1993), 2249–2254.
    • (1993) J. Exp. Med. , vol.178 , pp. 2249-2254
    • Flynn, J.L.1    Chan, J.2    Triebold, K.J.3    Dalton, D.K.4    Stewart, T.A.5    Bloom, B.R.6
  • 107
    • 84951336143 scopus 로고    scopus 로고
    • Unique role for ATG5 in neutrophil-mediated immunopathology during M. Tuberculosis infection
    • [107] Kimmey, J.M., Huynh, J.P., Weiss, L.A., Park, S., Kambal, A., Debnath, J., et al., Unique role for ATG5 in neutrophil-mediated immunopathology during M. Tuberculosis infection. Nature 528 (2015), 565–569, 10.1038/nature16451.
    • (2015) Nature , vol.528 , pp. 565-569
    • Kimmey, J.M.1    Huynh, J.P.2    Weiss, L.A.3    Park, S.4    Kambal, A.5    Debnath, J.6
  • 108
    • 33749264796 scopus 로고    scopus 로고
    • Autophagy-mediated reentry of Francisella tularensis into the endocytic compartment after cytoplasmic replication
    • [108] Checroun, C., Wehrly, T.D., Fischer, E.R., Hayes, S.F., Celli, J., Autophagy-mediated reentry of Francisella tularensis into the endocytic compartment after cytoplasmic replication. Proc. Natl. Acad. Sci. U.S.A. 103 (2006), 14,578–14,583, 10.1073/pnas.0601838103.
    • (2006) Proc. Natl. Acad. Sci. U.S.A. , vol.103 , pp. 14578-14583
    • Checroun, C.1    Wehrly, T.D.2    Fischer, E.R.3    Hayes, S.F.4    Celli, J.5
  • 109
    • 84866559918 scopus 로고    scopus 로고
    • Cytosolic clearance of replication-deficient mutants reveals Francisella tularensis interactions with the autophagic pathway
    • [109] Chong, A., Wehrly, T.D., Child, R., Hansen, B., Hwang, S., Virgin, H.W., et al., Cytosolic clearance of replication-deficient mutants reveals Francisella tularensis interactions with the autophagic pathway. Autophagy. 8 (2012), 1342–1356, 10.4161/auto.20808.
    • (2012) Autophagy. , vol.8 , pp. 1342-1356
    • Chong, A.1    Wehrly, T.D.2    Child, R.3    Hansen, B.4    Hwang, S.5    Virgin, H.W.6
  • 110
    • 84898731112 scopus 로고    scopus 로고
    • The Francisella O-antigen mediates survival in the macrophage cytosol via autophagy avoidance
    • [110] Case, E.D.R., Chong, A., Wehrly, T.D., Hansen, B., Child, R., Hwang, S., et al., The Francisella O-antigen mediates survival in the macrophage cytosol via autophagy avoidance. Cell. Microbiol. 16 (2014), 862–877, 10.1111/cmi.12246.
    • (2014) Cell. Microbiol. , vol.16 , pp. 862-877
    • Case, E.D.R.1    Chong, A.2    Wehrly, T.D.3    Hansen, B.4    Child, R.5    Hwang, S.6
  • 111
    • 33947416152 scopus 로고    scopus 로고
    • Autophagy limits Listeria monocytogenes intracellular growth in the early phase of primary infection
    • [111] Py, B.F., Lipinski, M.M., Yuan, J., Autophagy limits Listeria monocytogenes intracellular growth in the early phase of primary infection. Autophagy. 3 (2007), 117–125.
    • (2007) Autophagy. , vol.3 , pp. 117-125
    • Py, B.F.1    Lipinski, M.M.2    Yuan, J.3
  • 112
    • 41449103163 scopus 로고    scopus 로고
    • Avoiding death by autophagy: interactions of Listeria monocytogenes with the macrophage autophagy system
    • [112] Birmingham, C.L., Higgins, D.E., Brumell, J.H., Avoiding death by autophagy: interactions of Listeria monocytogenes with the macrophage autophagy system. Autophagy. 4 (2008), 368–371.
    • (2008) Autophagy. , vol.4 , pp. 368-371
    • Birmingham, C.L.1    Higgins, D.E.2    Brumell, J.H.3
  • 113
    • 50249111985 scopus 로고    scopus 로고
    • Stimulation of autophagy suppresses the intracellular survival of Burkholderia pseudomallei in mammalian cell lines
    • [113] Cullinane, M., Gong, L., Li, X., Lazar-Adler, N., Tra, T., Wolvetang, E., et al., Stimulation of autophagy suppresses the intracellular survival of Burkholderia pseudomallei in mammalian cell lines. Autophagy. 4 (2008), 744–753.
    • (2008) Autophagy. , vol.4 , pp. 744-753
    • Cullinane, M.1    Gong, L.2    Li, X.3    Lazar-Adler, N.4    Tra, T.5    Wolvetang, E.6
  • 114
    • 77954154527 scopus 로고    scopus 로고
    • Beta1 integrin-dependent engulfment of Yersinia enterocolitica by macrophages is coupled to the activation of autophagy and suppressed by type III protein secretion
    • [114] Deuretzbacher, A., Czymmeck, N., Reimer, R., Trülzsch, K., Gaus, K., Hohenberg, H., et al., Beta1 integrin-dependent engulfment of Yersinia enterocolitica by macrophages is coupled to the activation of autophagy and suppressed by type III protein secretion. J. Immunol. 183 (2009), 5847–5860, 10.4049/jimmunol.0804242.
    • (2009) J. Immunol. , vol.183 , pp. 5847-5860
    • Deuretzbacher, A.1    Czymmeck, N.2    Reimer, R.3    Trülzsch, K.4    Gaus, K.5    Hohenberg, H.6
  • 115
    • 77958107375 scopus 로고    scopus 로고
    • Escape of intracellular Shigella from autophagy requires binding to cholesterol through the type III effector, IcsB
    • [115] Kayath, C.A., Hussey, S., El hajjami, N., Nagra, K., Philpott, D., Allaoui, A., Escape of intracellular Shigella from autophagy requires binding to cholesterol through the type III effector, IcsB. Microbes Infect. 12 (2010), 956–966, 10.1016/j.micinf.2010.06.006.
    • (2010) Microbes Infect. , vol.12 , pp. 956-966
    • Kayath, C.A.1    Hussey, S.2    El hajjami, N.3    Nagra, K.4    Philpott, D.5    Allaoui, A.6
  • 116
    • 84890305743 scopus 로고    scopus 로고
    • Streptococcus pyogenes escapes from autophagy
    • [116] Nakagawa, I., Streptococcus pyogenes escapes from autophagy. Cell Host Microbe. 14 (2013), 604–606, 10.1016/j.chom.2013.11.012.
    • (2013) Cell Host Microbe. , vol.14 , pp. 604-606
    • Nakagawa, I.1
  • 117
    • 84869886358 scopus 로고    scopus 로고
    • The Legionella effector RavZ inhibits host autophagy through irreversible Atg8 deconjugation
    • [117] Choy, A., Dancourt, J., Mugo, B., O'Connor, T.J., Isberg, R.R., Melia, T.J., et al., The Legionella effector RavZ inhibits host autophagy through irreversible Atg8 deconjugation. Science. 338 (2012), 1072–1076, 10.1126/science.1227026.
    • (2012) Science. , vol.338 , pp. 1072-1076
    • Choy, A.1    Dancourt, J.2    Mugo, B.3    O'Connor, T.J.4    Isberg, R.R.5    Melia, T.J.6
  • 118
    • 84946782287 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis inhibits RAB7 recruitment to selectively modulate autophagy flux in macrophages
    • [118] Chandra, P., Ghanwat, S., Matta, S.K., Yadav, S.S., Mehta, M., Siddiqui, Z., et al., Mycobacterium tuberculosis inhibits RAB7 recruitment to selectively modulate autophagy flux in macrophages. Sci. Rep., 5, 2015, 16,320, 10.1038/srep16320.
    • (2015) Sci. Rep. , vol.5 , pp. 16320
    • Chandra, P.1    Ghanwat, S.2    Matta, S.K.3    Yadav, S.S.4    Mehta, M.5    Siddiqui, Z.6
  • 119
    • 0036838699 scopus 로고    scopus 로고
    • Critical role of mitochondrial damage in determining outcome of macrophage infection with Mycobacterium tuberculosis
    • [119] Duan, L., Gan, H., Golan, D.E., Remold, H.G., Critical role of mitochondrial damage in determining outcome of macrophage infection with Mycobacterium tuberculosis. J. Immunol. 169 (2002), 5181–5187.
    • (2002) J. Immunol. , vol.169 , pp. 5181-5187
    • Duan, L.1    Gan, H.2    Golan, D.E.3    Remold, H.G.4
  • 120
    • 84928537166 scopus 로고    scopus 로고
    • Mitochondrial DNA stress primes the antiviral innate immune response
    • [120] West, A.P., Khoury-Hanold, W., Staron, M., Tal, M.C., Pineda, C.M., Lang, S.M., et al., Mitochondrial DNA stress primes the antiviral innate immune response. Nature. 520 (2015), 553–557, 10.1038/nature14156.
    • (2015) Nature. , vol.520 , pp. 553-557
    • West, A.P.1    Khoury-Hanold, W.2    Staron, M.3    Tal, M.C.4    Pineda, C.M.5    Lang, S.M.6
  • 121
    • 84885576570 scopus 로고    scopus 로고
    • The ubiquitin ligase parkin mediates resistance to intracellular pathogens
    • [121] Manzanillo, P.S., Ayres, J.S., Watson, R.O., Collins, A.C., Souza, G., Rae, C.S., et al., The ubiquitin ligase parkin mediates resistance to intracellular pathogens. Nature. 501 (2013), 512–516, 10.1038/nature12566.
    • (2013) Nature. , vol.501 , pp. 512-516
    • Manzanillo, P.S.1    Ayres, J.S.2    Watson, R.O.3    Collins, A.C.4    Souza, G.5    Rae, C.S.6


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