Structural Biochemistry of a Vibrio cholerae Dinucleotide Cyclase Reveals Cyclase Activity Regulation by Folates

Molecular Cell

Volumn 55, Issue 6, 2014, Pages 931-937

  Zhu, Deyu ^b   Wang, Lijun ^a,c   Shang, Guijun ^b   Liu, Xue ^a   Zhu, Jing ^b   Lu, Defen ^b   Wang, Lei ^a,c   Kan, Biao ^c,d   Zhang, Jing ren ^a   Xiang, Ye ^a,c  

^a Tsinghua University   (China)

^b SHANDONG UNIVERSITY   (China)

^c ZHEJIANG UNIVERSITY   (China)

^d National Institute for Communicable Disease Control and Prevention   (China)

Author keywords

[No Author keywords available]

Indexed keywords

5 METHYLTETRAHYDROFOLIC ACID; BACTERIAL ENZYME; DINUCLEOTIDE; DINUCLEOTIDE CYCLASE DNCV; FOLIC ACID; UNCLASSIFIED DRUG; 5 METHYLTETRAHYDROHOMOFOLIC ACID; 5-METHYLTETRAHYDROHOMOFOLIC ACID; BACTERIAL PROTEIN; CYCLIC AMP; CYCLIC GMP; DRUG DERIVATIVE;

ARTICLE; BACTERIAL METABOLISM; CRYSTAL STRUCTURE; CRYSTALLOGRAPHY; ENZYME ACTIVITY; ENZYME REGULATION; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; MUTAGENESIS; NONHUMAN; ORTHOLOGY; PROTEIN FUNCTION; SECOND MESSENGER; SEQUENCE ANALYSIS; VIBRIO CHOLERAE; AMINO ACID SEQUENCE; CHEMICAL STRUCTURE; CHEMISTRY; ENZYME ACTIVE SITE; ENZYMOLOGY; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PROTEIN TERTIARY STRUCTURE; SITE DIRECTED MUTAGENESIS; X RAY CRYSTALLOGRAPHY;

AMINO ACID SEQUENCE; BACTERIAL PROTEINS; CATALYTIC DOMAIN; CONSERVED SEQUENCE; CRYSTALLOGRAPHY, X-RAY; CYCLIC AMP; CYCLIC GMP; FOLIC ACID; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROTEIN STRUCTURE, TERTIARY; VIBRIO CHOLERAE;

EID: 84907964159     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2014.08.001     Document Type: Article

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