Sox2 functions as a sequence-specific DNA sensor in neutrophils to initiate innate immunity against microbial infection

Nature Immunology

Volumn 16, Issue 4, 2015, Pages 366-378

  Xia, Pengyan ^a   Wang, Shuo ^a   Ye, Buqing ^a   Du, Ying ^a   Huang, Guanling ^a   Zhu, Pingping ^a   Fan, Zusen ^a  

^a INSTITUTE OF BIOPHYSICS   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL DNA; BINDING PROTEIN; HIGH MOBILITY GROUP PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; TAB2 PROTEIN; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR SOX2; TRANSFORMING GROWTH FACTOR BETA ACTIVATED KINASE 1; UNCLASSIFIED DRUG; MAP KINASE KINASE KINASE 7; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE; SIGNAL TRANSDUCING ADAPTOR PROTEIN; SOX2 PROTEIN, MOUSE; TAB2 PROTEIN, MOUSE; TOLL LIKE RECEPTOR; TRANSCRIPTION FACTOR SOX;

ANIMAL CELL; ARTICLE; BACTERIAL IMMUNITY; BACTERIAL INFECTION; CELL SPECIFICITY; COMPLEX FORMATION; CONTROLLED STUDY; CYTOPLASM; DIMERIZATION; DNA SEQUENCE; HUMAN; HUMAN CELL; INNATE IMMUNITY; MOLECULAR SENSOR; MOUSE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; ANIMAL; DEFICIENCY; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; LISTERIA MONOCYTOGENES; LISTERIOSIS; MICROBIOLOGY; MORTALITY; PROTEIN MULTIMERIZATION; SIGNAL TRANSDUCTION; SURVIVAL;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CYTOPLASM; DNA, BACTERIAL; GENE EXPRESSION REGULATION; HUMANS; IMMUNITY, INNATE; LISTERIA MONOCYTOGENES; LISTERIOSIS; MAP KINASE KINASE KINASES; MICE; NEUTROPHILS; NF-KAPPA B; PROTEIN MULTIMERIZATION; SIGNAL TRANSDUCTION; SOXB1 TRANSCRIPTION FACTORS; SURVIVAL ANALYSIS; TOLL-LIKE RECEPTORS; TRANSCRIPTION FACTOR AP-1;

EID: 84925412026     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.3117     Document Type: Article

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