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Volumn 88, Issue 2, 2014, Pages 974-981

Adenovirus detection by the cGAS/STING/TBK1 DNA sensing cascade

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; ADENOSINE PHOSPHATE SYNTHASE; BETA INTERFERON; CELL PROTEIN; CYCLIC GMP; INTERFERON REGULATORY FACTOR 3; LENTIVIRUS VECTOR; LYASE; PROTEIN ISG15; PROTEIN ISG54; PROTEIN KINASE; PROTEIN STING; PROTEIN TBK1; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG; VIRUS DNA;

EID: 84891702580     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.02702-13     Document Type: Article
Times cited : (183)

References (49)
  • 2
    • 66149151694 scopus 로고    scopus 로고
    • Adenovirus induction of IRF3 occurs through a binary trigger targeting JNK and TBK-1 kinase cascades and type I IFN autocrine signaling
    • 11 February
    • Nociari M, Ocheretina O, Murphy M, Falck-Pedersen E. 11 February 2009. Adenovirus induction of IRF3 occurs through a binary trigger targeting JNK and TBK-1 kinase cascades and type I IFN autocrine signaling. J. Virol. http://dx.doi.org/10.1128/JVI.02591-08.
    • (2009) J. Virol
    • Nociari, M.1    Ocheretina, O.2    Murphy, M.3    Falck-Pedersen, E.4
  • 3
    • 34247116994 scopus 로고    scopus 로고
    • Sensing infection by adenovirus: Toll-like receptor-independent viral DNA recognition signals activation of the interferon regulatory factor 3 master regulator
    • Nociari M, Ocheretina O, Schoggins JW, Falck-Pedersen E. 2007. Sensing infection by adenovirus: Toll-like receptor-independent viral DNA recognition signals activation of the interferon regulatory factor 3 master regulator. J. Virol. 81:4145-4157. http://dx.doi.org/10.1128/JVI.02685-06.
    • (2007) J. Virol. , vol.81 , pp. 4145-4157
    • Nociari, M.1    Ocheretina, O.2    Schoggins, J.W.3    Falck-Pedersen, E.4
  • 4
    • 33947396347 scopus 로고    scopus 로고
    • Innate immune response to adenoviral vectors is mediated by both Toll-like receptor-dependent and -independent pathways
    • Zhu J, Huang X, Yang Y. 2007. Innate immune response to adenoviral vectors is mediated by both Toll-like receptor-dependent and -independent pathways. J. Virol. 81:3170-3180. http://dx.doi.org/10.1128/JVI.02192-06.
    • (2007) J. Virol. , vol.81 , pp. 3170-3180
    • Zhu, J.1    Huang, X.2    Yang, Y.3
  • 5
    • 84861373256 scopus 로고    scopus 로고
    • Sensing adenovirus infection: activation of interferon regulatory factor 3 in RAW 264.7 cells
    • Stein SC, Falck-Pedersen E. 2012. Sensing adenovirus infection: activation of interferon regulatory factor 3 in RAW 264.7 cells. J. Virol. 86:4527-4537. http://dx.doi.org/10.1128/JVI.07071-11.
    • (2012) J. Virol. , vol.86 , pp. 4527-4537
    • Stein, S.C.1    Falck-Pedersen, E.2
  • 6
    • 84870724934 scopus 로고    scopus 로고
    • Cell-specific regulation of nucleic acid sensor cascades: a controlling interest in the antiviral response
    • Stein SC, Lam E, Falck-Pedersen E. 2012. Cell-specific regulation of nucleic acid sensor cascades: a controlling interest in the antiviral response. J. Virol. 86:13303-13312. http://dx.doi.org/10.1128/JVI.02296-12.
    • (2012) J. Virol. , vol.86 , pp. 13303-13312
    • Stein, S.C.1    Lam, E.2    Falck-Pedersen, E.3
  • 7
    • 53349178089 scopus 로고    scopus 로고
    • STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling
    • Ishikawa H, Barber GN. 2008. STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling. Nature 455:674-678. http://dx.doi.org/10.1038/nature07317.
    • (2008) Nature , vol.455 , pp. 674-678
    • Ishikawa, H.1    Barber, G.N.2
  • 8
    • 70349943834 scopus 로고    scopus 로고
    • STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity
    • Ishikawa H, Ma Z, Barber GN. 2009. STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity. Nature 461:788-792. http://dx.doi.org/10.1038/nature08476.
    • (2009) Nature , vol.461 , pp. 788-792
    • Ishikawa, H.1    Ma, Z.2    Barber, G.N.3
  • 10
    • 0038660668 scopus 로고    scopus 로고
    • Identification of the minimal phosphoacceptor site required for in vivo activation of interferon regulatory factor 3 in response to virus and double-stranded RNA
    • Servant MJ, Grandvaux N, ten Oever BR, Duguay D, Lin R, Hiscott J. 2003. Identification of the minimal phosphoacceptor site required for in vivo activation of interferon regulatory factor 3 in response to virus and double-stranded RNA. J. Biol. Chem. 278:9441-9447. http://dx.doi.org/10.1074/jbc.M209851200.
    • (2003) J. Biol. Chem. , vol.278 , pp. 9441-9447
    • Servant, M.J.1    Grandvaux, N.2    ten Oever, B.R.3    Duguay, D.4    Lin, R.5    Hiscott, J.6
  • 11
    • 41949092999 scopus 로고    scopus 로고
    • Phosphorylation of IRF-3 on Ser 339 generates a hyperactive form of IRF-3 through regulation of dimerization and CBP association
    • Clément JF, Bibeau-Poirier A, Gravel SP, Grandvaux N, Bonneil E, Thibault P, Meloche S, Servant MJ. 2008. Phosphorylation of IRF-3 on Ser 339 generates a hyperactive form of IRF-3 through regulation of dimerization and CBP association. J. Virol. 82:3984-3996. http://dx.doi.org/10.1128/JVI.02526-07.
    • (2008) J. Virol. , vol.82 , pp. 3984-3996
    • Clément, J.F.1    Bibeau-Poirier, A.2    Gravel, S.P.3    Grandvaux, N.4    Bonneil, E.5    Thibault, P.6    Meloche, S.7    Servant, M.J.8
  • 12
    • 34250017968 scopus 로고    scopus 로고
    • An atomic model of the interferon-beta enhanceosome
    • Panne D, Maniatis T, Harrison SC. 2007. An atomic model of the interferon-beta enhanceosome. Cell 129:1111-1123. http://dx.doi.org/10.1016/j.cell.2007.05.019.
    • (2007) Cell , vol.129 , pp. 1111-1123
    • Panne, D.1    Maniatis, T.2    Harrison, S.C.3
  • 13
    • 84875254887 scopus 로고    scopus 로고
    • DNA recognition in immunity and disease
    • Holm CK, Paludan SR, Fitzgerald KA. 2013. DNA recognition in immunity and disease. Curr. Opin. Immunol. 25:13-18. http://dx.doi.org/10.1016/j.coi.2012.12.006.
    • (2013) Curr. Opin. Immunol. , vol.25 , pp. 13-18
    • Holm, C.K.1    Paludan, S.R.2    Fitzgerald, K.A.3
  • 15
    • 79251506939 scopus 로고    scopus 로고
    • The N-ethyl-N-nitrosourea-induced Goldenticket mouse mutant reveals an essential function of Sting in the in vivo interferon response to Listeria monocytogenes and cyclic dinucleotides
    • Sauer JD, Sotelo-Troha K, von Moltke J, Monroe KM, Rae CS, Brubaker SW, Hyodo M, Hayakawa Y, Woodward JJ, Portnoy DA, Vance RE. 2011. The N-ethyl-N-nitrosourea-induced Goldenticket mouse mutant reveals an essential function of Sting in the in vivo interferon response to Listeria monocytogenes and cyclic dinucleotides. Infect. Immun. 79:688-694. http://dx.doi.org/10.1128/IAI.00999-10.
    • (2011) Infect. Immun. , vol.79 , pp. 688-694
    • Sauer, J.D.1    Sotelo-Troha, K.2    von Moltke, J.3    Monroe, K.M.4    Rae, C.S.5    Brubaker, S.W.6    Hyodo, M.7    Hayakawa, Y.8    Woodward, J.J.9    Portnoy, D.A.10    Vance, R.E.11
  • 16
    • 84863722786 scopus 로고    scopus 로고
    • The structural basis for the sensing and binding of cyclic di-GMP by STING
    • Huang YH, Liu XY, Du XX, Jiang ZF, Su XD. 2012. The structural basis for the sensing and binding of cyclic di-GMP by STING. Nat. Struct. Mol. Biol. 19:728-730. http://dx.doi.org/10.1038/nsmb.2333.
    • (2012) Nat. Struct. Mol. Biol. , vol.19 , pp. 728-730
    • Huang, Y.H.1    Liu, X.Y.2    Du, X.X.3    Jiang, Z.F.4    Su, X.D.5
  • 17
    • 84869208004 scopus 로고    scopus 로고
    • 5,6-Dimethylxanthenone-4-acetic acid (DMXAA) activates stimulator of interferon gene (STING)-dependent innate immune pathways and is regulated by mitochondrial membrane potential
    • Prantner D, Perkins DJ, Lai W, Williams MS, Sharma S, Fitzgerald KA, Vogel SN. 2012. 5,6-Dimethylxanthenone-4-acetic acid (DMXAA) activates stimulator of interferon gene (STING)-dependent innate immune pathways and is regulated by mitochondrial membrane potential. J. Biol. Chem. 287:39776-39788. http://dx.doi.org/10.1074/jbc.M112.382986.
    • (2012) J. Biol. Chem. 287:39776-39788
    • Prantner, D.1    Perkins, D.J.2    Lai, W.3    Williams, M.S.4    Sharma, S.5    Fitzgerald, K.A.6    Vogel, S.N.7
  • 18
    • 84863726252 scopus 로고    scopus 로고
    • Structure of STING bound to cyclic di-GMP reveals the mechanism of cyclic dinucleotide recognition by the immune system
    • Shu C, Yi G, Watts T, Kao CC, Li P. 2012. Structure of STING bound to cyclic di-GMP reveals the mechanism of cyclic dinucleotide recognition by the immune system. Nat. Struct. Mol. Biol. 19:722-724. http://dx.doi.org/10.1038/nsmb.2331.
    • (2012) Nat. Struct. Mol. Biol. , vol.19 , pp. 722-724
    • Shu, C.1    Yi, G.2    Watts, T.3    Kao, C.C.4    Li, P.5
  • 19
    • 84873711885 scopus 로고    scopus 로고
    • Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway
    • Sun L, Wu J, Du F, Chen X, Chen ZJ. 2013. Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway. Science 339:786-791. http://dx.doi.org/10.1126/science.1232458.
    • (2013) Science , vol.339 , pp. 786-791
    • Sun, L.1    Wu, J.2    Du, F.3    Chen, X.4    Chen, Z.J.5
  • 20
    • 84873724533 scopus 로고    scopus 로고
    • Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA
    • Wu J, Sun L, Chen X, Du F, Shi H, Chen C, Chen ZJ. 2013. Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA. Science 339:826-830. http://dx.doi.org/10.1126/science.1229963.
    • (2013) Science , vol.339 , pp. 826-830
    • Wu, J.1    Sun, L.2    Chen, X.3    Du, F.4    Shi, H.5    Chen, C.6    Chen, Z.J.7
  • 23
    • 84878592773 scopus 로고    scopus 로고
    • Structure of human cGAS reveals a conserved family of second-messenger enzymes in innate immunity
    • Kranzusch PJ, Lee AS, Berger JM, Doudna JA. 2013. Structure of human cGAS reveals a conserved family of second-messenger enzymes in innate immunity. Cell Rep. 3:1362-1368. http://dx.doi.org/10.1016/j.celrep.2013.05.008.
    • (2013) Cell Rep. , vol.3 , pp. 1362-1368
    • Kranzusch, P.J.1    Lee, A.S.2    Berger, J.M.3    Doudna, J.A.4
  • 26
    • 84880508067 scopus 로고    scopus 로고
    • Cyclic GMP-AMP containing mixed phosphodiester linkages is an endogenous high-affinity ligand for STING
    • Zhang X, Shi H, Wu J, Zhang X, Sun L, Chen C, Chen ZJ. 2013. Cyclic GMP-AMP containing mixed phosphodiester linkages is an endogenous high-affinity ligand for STING. Mol. Cell 51:226-235. http://dx.doi.org/10.1016/j.molcel.2013.05.022.
    • (2013) Mol. Cell , vol.51 , pp. 226-235
    • Zhang, X.1    Shi, H.2    Wu, J.3    Zhang, X.4    Sun, L.5    Chen, C.6    Chen, Z.J.7
  • 28
    • 33750307313 scopus 로고    scopus 로고
    • Fiber and penton base capsid modifications yield diminished Ad5 transduction and proinflammatory gene expression with retention of antigen specific humoral immunity
    • Schoggins JW, Falck-Pedersen E. 2006. Fiber and penton base capsid modifications yield diminished Ad5 transduction and proinflammatory gene expression with retention of antigen specific humoral immunity. J. Virol. 80:10634-10644. http://dx.doi.org/10.1128/JVI.01359-06.
    • (2006) J. Virol. , vol.80 , pp. 10634-10644
    • Schoggins, J.W.1    Falck-Pedersen, E.2
  • 29
    • 3242890471 scopus 로고    scopus 로고
    • siRNA Selection Server: an automated siRNA oligonucleotide prediction server
    • Yuan B, Latek R, Hossbach M, Tuschl T, Lewitter F. 2004. siRNA Selection Server: an automated siRNA oligonucleotide prediction server. Nucleic Acids Res. 32:W130-W134. http://dx.doi.org/10.1093/nar/gkh366.
    • (2004) Nucleic Acids Res , vol.32
    • Yuan, B.1    Latek, R.2    Hossbach, M.3    Tuschl, T.4    Lewitter, F.5
  • 30
    • 44949231424 scopus 로고    scopus 로고
    • Analyzing real-time PCR data by the comparative C(T) method
    • Schmittgen TD, Livak KJ. 2008. Analyzing real-time PCR data by the comparative C(T) method. Nat. Protoc. 3:1101-1108. http://dx.doi.org/10.1038/nprot.2008.73.
    • (2008) Nat. Protoc. , vol.3 , pp. 1101-1108
    • Schmittgen, T.D.1    Livak, K.J.2
  • 31
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-delta delta C(T)) method
    • Livak KJ, Schmittgen TD. 2001. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-delta delta C(T)) method. Methods 25:402-408. http://dx.doi.org/10.1006/meth.2001.1262.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 34
    • 80052152283 scopus 로고    scopus 로고
    • The PYHIN protein family as mediators of host defenses
    • Schattgen SA, Fitzgerald KA. 2011. The PYHIN protein family as mediators of host defenses. Immunol. Rev. 243:109-118. http://dx.doi.org/10.1111/j.1600-065X.2011.01053.x.
    • (2011) Immunol. Rev. , vol.243 , pp. 109-118
    • Schattgen, S.A.1    Fitzgerald, K.A.2
  • 38
    • 40449097257 scopus 로고    scopus 로고
    • The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response
    • Muruve DA, Petrilli V, Zaiss AK, White LR, Clark SA, Ross PJ, Parks RJ, Tschopp J. 2008. The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response. Nature 452:103-107. http://dx.doi.org/10.1038/nature06664.
    • (2008) Nature , vol.452 , pp. 103-107
    • Muruve, D.A.1    Petrilli, V.2    Zaiss, A.K.3    White, L.R.4    Clark, S.A.5    Ross, P.J.6    Parks, R.J.7    Tschopp, J.8
  • 40
    • 58749100879 scopus 로고    scopus 로고
    • Receptor-interacting protein homotypic interaction motif-dependent control of NF-kappa B activation via the DNA-dependent activator of IFN regulatory factors
    • Kaiser WJ, Upton JW, Mocarski ES. 2008. Receptor-interacting protein homotypic interaction motif-dependent control of NF-kappa B activation via the DNA-dependent activator of IFN regulatory factors. J. Immunol. 181:6427-6434.
    • (2008) J. Immunol. , vol.181 , pp. 6427-6434
    • Kaiser, W.J.1    Upton, J.W.2    Mocarski, E.S.3
  • 42
    • 84858420051 scopus 로고    scopus 로고
    • DAI/ZBP1/DLM-1 complexes with RIP3 to mediate virus-induced programmed necrosis that is targeted by murine cytomegalovirus vIRA
    • Upton JW, Kaiser WJ, Mocarski ES. 2012. DAI/ZBP1/DLM-1 complexes with RIP3 to mediate virus-induced programmed necrosis that is targeted by murine cytomegalovirus vIRA. Cell Host Microbe 11:290-297. http://dx.doi.org/10.1016/j.chom.2012.01.016.
    • (2012) Cell Host Microbe , vol.11 , pp. 290-297
    • Upton, J.W.1    Kaiser, W.J.2    Mocarski, E.S.3
  • 43
    • 84856431819 scopus 로고    scopus 로고
    • RNA therapeutics: beyond RNA interference and antisense oligonucleotides
    • Kole R, Krainer AR, Altman S. 2012. RNA therapeutics: beyond RNA interference and antisense oligonucleotides. Nat. Rev. Drug Discov. 11:125-140. http://dx.doi.org/10.1038/nrd3625.
    • (2012) Nat. Rev. Drug Discov. , vol.11 , pp. 125-140
    • Kole, R.1    Krainer, A.R.2    Altman, S.3
  • 44
    • 84875792696 scopus 로고    scopus 로고
    • RNA-based mechanisms regulating host-virus interactions
    • Zhou R, Rana TM. 2013. RNA-based mechanisms regulating host-virus interactions. Immunol. Rev. 253:97-111. http://dx.doi.org/10.1111/imr.12053.
    • (2013) Immunol. Rev. , vol.253 , pp. 97-111
    • Zhou, R.1    Rana, T.M.2
  • 45
    • 77957785465 scopus 로고    scopus 로고
    • Emerging role of ISG15 in antiviral immunity
    • Skaug B, Chen ZJ. 2010. Emerging role of ISG15 in antiviral immunity. Cell 143:187-190. http://dx.doi.org/10.1016/j.cell.2010.09.033.
    • (2010) Cell , vol.143 , pp. 187-190
    • Skaug, B.1    Chen, Z.J.2
  • 46
    • 84884134473 scopus 로고    scopus 로고
    • Extensive cooperation of immune master regulators IRF3 and NFkappaB in RNA Pol II recruitment and pause release in human innate antiviral transcription
    • Freaney JE, Kim R, Mandhana R, Horvath CM. 2013. Extensive cooperation of immune master regulators IRF3 and NFkappaB in RNA Pol II recruitment and pause release in human innate antiviral transcription. Cell Rep. 4:959-973. http://dx.doi.org/10.1016/j.celrep.2013.07.043.
    • (2013) Cell Rep. , vol.4 , pp. 959-973
    • Freaney, J.E.1    Kim, R.2    Mandhana, R.3    Horvath, C.M.4
  • 48
    • 70349736116 scopus 로고    scopus 로고
    • Cross-regulation of signaling pathways by interferon-gamma: implications for immune responses and autoimmune diseases
    • Hu X, Ivashkiv LB. 2009. Cross-regulation of signaling pathways by interferon-gamma: implications for immune responses and autoimmune diseases. Immunity 31:539-550. http://dx.doi.org/10.1016/j.immuni.2009.09.002.
    • (2009) Immunity , vol.31 , pp. 539-550
    • Hu, X.1    Ivashkiv, L.B.2
  • 49
    • 33846532947 scopus 로고    scopus 로고
    • Preferential activation of Toll-like receptor nine by CD46-utilizing adenoviruses
    • Iacobelli-Martinez M, Nemerow GR. 2007. Preferential activation of Toll-like receptor nine by CD46-utilizing adenoviruses. J. Virol. 81:1305-1312. http://dx.doi.org/10.1128/JVI.01926-06.
    • (2007) J. Virol. , vol.81 , pp. 1305-1312
    • Iacobelli-Martinez, M.1    Nemerow, G.R.2


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